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Ancestry Anomaly Scores for UK Biobank painting of from Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations

    Dataset

    Description

    This is data generated from the paper " Elevated genetic risk for multiple sclerosis emerged in steppe pastoralist populations " by Barrie et al. Nature 2024 (https://www.nature.com/articles/s41586-023\
    -06618-z#Sec3).

    This describes the results from the github https://github.com/danjlawson/ms_paper that generates "Ancestry Anomaly Scores" or AAS.

    This is summary-level data.

    Inventory:
    aas_scores/meanpainting.csv.gz: Average Painting for each reference population for each SNP.
    aas_scores/joint_whitenened_anamaly_pvals.csv.gz: p-values for the existence of a local ancestry anomaly at a given SNP, "Whitened" as described in the paper.
    aas_scores/XXX_allchr.csv.gz: raw p-values for each ancestry XXX.

    The seven populations are:

    Yamnaya
    EastAsian
    WHG
    EHG
    Farmer
    African
    CHG
    Date made available24 Jun 2025
    PublisherUniversity of Bristol

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