Cytokines GWAS results



This dataset contains the meta-analysis summary statistics for a genome-wide association study (GWAS) of inflammatory cytokines, conducted within three Finnish cohorts (YFS and FINRISK 1997 and 2002).

This analysis represents a re-run of a published GWAS that is reported in Ahola-Olli et al. (2017) Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors, American Journal of Human Genetics 100,40-50. DOI: 10.1016/j.ajhg.2016.11.007.

The results reported here are the meta-analysis summary statistics for the 41 inflammatory cytokines without fitting BMI as a covariate in the model (as was done in the previously published GWAS). Results are filtered such that only SNPs with results for 2 or more of the 3 cohorts remain.

This dataset is published in support of the article Kalaoja, M., Corbin, L.J. et al., "The Role of Inflammatory Cytokines as Intermediates in the Pathway From Increased Adiposity to Disease", Obesity, DOI: 10.1002/oby23060
Date made available31 Oct 2020
PublisherUniversity of Bristol
  • The role of inflammatory cytokines as intermediates in the pathway from increased adiposity to disease

    Kalaoja, M., Corbin, L. J., Tan, Y., Ahola-Olli, A. V., Havulinna, A. S., Santalahti, K., Pitkänen, N., Lehtimäki, T., Lyytikäinen, L. P., Raitoharju, E., Seppala, I., Kahonen, M., Ripatti, S., Palotie, A., Perola, M., Viikari, J., Jalkanen, S., Maksimow, M., Salomaa, V., Salmi, M. & 3 others, Raitakari, O. T., Kettunen, J. & Timpson, N. J., 1 Feb 2021, In: Obesity. 29, 2, p. 428-437 10 p.

    Research output: Contribution to journalArticle (Academic Journal)peer-review

    Open Access
    2 Citations (Scopus)
    32 Downloads (Pure)

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