Data from 72hXeHT therapy after HIE (03-2019)



This project is aimed at investiagting the feasibility of administration of 72-78 hours of xenon with hypothermia after global hypoxic-ischemic insult or sham insult with or without hypothermia in newborn pigs. The study had four piglets that received 78 hours of xenon following hypoxic-ischaemic insult and three piglets that received 72 hours of xenon following sham insult under normothermia. Data deposited include the technical feasibility data of administering xenon and oxygen at a constant concentration using an automated controller in a closed loop system. Data pertaining to the lung function and gas exchange also included.
Date made available21 Mar 2019
PublisherUniversity of Bristol

Research Output

  • 1 Article (Academic Journal)

Closed-circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects

Dingley, J., Okano, S., Lee-Kelland, R., Scull-Brown, E., Thoresen, M. & Chakkarapani, E., 21 Jan 2020, In : PLoS ONE. 15, 1, 18 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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    Cite this

    Chakkarapani, E. (Creator), Thoresen, M. (Creator), Jary, S. (Creator) (21 Mar 2019). Data from 72hXeHT therapy after HIE (03-2019). University of Bristol. 10.5523/bris.1oj2xiwbpcoi12n4b5wba28lqi