Emulating the MERINO trial analysis dataset

This dataset contains data on the 121 participants who met the eligibility criteria and were included in the analysis of the emulation of the MERINO trial (Evans et al.). Patients were included if they had a BSI with E. coli or Klebsiella spp. that was resistant to Ceftriaxone and/or Cefotaxime and susceptible to both meropenem and piperacillin-tazobactam and treatment was started within 72 hours of blood culture. Patients that would have otherwise been eligible but did not start any of the study drugs (meropenem or piperacillin-tazobactam) within the 72 hours window were considered ineligible and excluded from the emulated trial population. All participants were aged 18 years and over. Polymicrobial infections and repeat episodes were excluded.