Description
The Cross-Attention conditional generative adversarial networks (XAcGAN) model is a proposed system to provide an alternative to fluorescent staining protocols. Focussing on the morphology of the nuclei during the process of apoptosis, the XAcGAN model generates images illustrating the apoptopic nuclei derived from only bright field images. The uploaded images were the ground truth used to train the model. They represent CHO-K1 cells with the nuclei, mitochondria and actin filaments stained with hoechst, mitospy and phalloidin respectively. These cells were induced to undergo apoptosis via exposure to 1 µM of staurosporine. The image sets consist of z-stacks, 7.2 µm in length and consisting of 24 slices spaced 0.3 µm apart.
Date made available | 2 Nov 2022 |
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Publisher | University of Bristol |
Student theses
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Deep Learning Methods for Biological Image Translation and Registration
Wang, R. (Author), Achim, A. (Supervisor), Cross, S. (Supervisor) & Jepson, M. (Supervisor), 18 Jun 2024Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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