Research Output

1972

REORGANISATION OF THE NATIONAL HEALTH SERVICE

Kirwan, J., 4 Nov 1972, In : Lancet. 300, 7784, 1 p.

Research output: Contribution to journalLetter (Academic Journal)

Some effects of dietary B6 deficiency and 4-deoxypyridoxine on gamma-aminobutyric acid metabolism in rat brain.

Bayoumi RA, RA., Kirwan, J. R. & Smith, WRD., 1972, In : Journal of Neurochemistry. 19, p. 569-576

Research output: Contribution to journalArticle (Academic Journal)

1973

ECONOMY IN THE BRAIN

Kirwan, J., 19 May 1973, In : Lancet. 301, 7812, 1 p.

Research output: Contribution to journalLetter (Academic Journal)

Hypoglycaemia and the regulation of fasting glucose metabolism in malnutrition

Stevens, MCG., Kerr, DS., Picou, DIM. & Robinson, HM., 1973, Endocrine Aspects of Malnutrition. Kroc Foundation, p. 313 - 341 28 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

1974

Utilisation of energy reserves in malnourished children

Stevens, MCG., Kerr, DS., Picou, DIM. & Robinson, HM., 1974, In : Proceedings of the XIV International Congress on Paediatrics. 10, p. 80 - 83 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Proceedings: The oxygen affinity of horse and human myoglobins

Boulton, F. E. & Holly, J. M., 1975, In : Journal of Physiology. 248, 1, p. 32P-33P

Research output: Contribution to journalArticle (Academic Journal)

Protein conservation without decreased gluconeogenesis in malnourished infants

Stevens, MCG., Kerr, DS., Picou, DIM. & Robinson, HM., 1975, In : Pediatric Research. 9, p. 351 1 p.

Research output: Contribution to journalArticle (Academic Journal)

1976

Absorption of large oral doses of 5-formyltetrahydrofolate in man

Kirwan, J. R. & Narebor, E. M., 1 Jan 1976, In : British Journal of Cancer. 34, 6, p. 671-673 3 p.

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)
1977

ELECTROCARDIOGRAPHIC ABNORMALITIES IN WOMEN TAKING ORAL CONTRACEPTIVES

Kirwan, J., Mcsorley, D. & Wynn, V., 10 Sep 1977, In : Lancet. 310, 8037, 1 p.

Research output: Contribution to journalLetter (Academic Journal)

3 Citations (Scopus)
1978

Fasting Metabolism in Infants, I: Effect of severe undernutrition on energy and protein utilisation

Stevens, MCG., Kerr, DS. & Robinson, HM., 1978, In : Metabolism. 27, p. 411 - 435 25 p.

Research output: Contribution to journalArticle (Academic Journal)

Fasting Metabolism in Infants, II: Effect of severe undernutrition and infusions of alanine on glucose production estimated with U-13C-glucose

Stevens, MCG., Kerr, DS. & Picou, DIM., 1978, In : Metabolism. 27, p. 831 - 847

Research output: Contribution to journalArticle (Academic Journal)

Preliminary investigation into a new method of assessing the quality of anaesthesia: the cardiovascular response to a measured noxious stimulus

Savege, T. M., Dubois, M., Frank, M. & Holly, J. M., 1978, In : British Journal of Anaesthesia. 50, 5, p. 481-488 8 p.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)
1980

Plasma concentrations of alphaxalone by gas chromatography: comparison with other gas chromatographic methods and gas chromatography-mass spectrometry

Sear, J. W., Holly, J. M., Trafford, D. J. & Makin, H. L., 1980, In : Journal of Pharmacy and Pharmacology. 32, 5, p. 349-52 4 p.

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)
1981

Acute splenic sequestration and hypersplenism in the first five years in homozygous Sickly Cell Disease

Stevens, MCG., Rogers, DW., Sergeant, GR. & Topley, JM., 1981, In : Archives of Disease in Childhood. 56, p. 765 - 770 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Blood pressure and hormonal changes following alteration in dietary sodium and potassium in mild essential hypertension

Parfrey, P. S., Vandenburg, M. J., Wright, P., Holly, J. M., Goodwin, F. J., Evans, S. J. & Ledingham, J. M., 1981, In : Lancet. 1, 8211, p. 59-63 5 p.

Research output: Contribution to journalArticle (Academic Journal)

55 Citations (Scopus)

Blood pressure and hormonal changes following alteration in dietary sodium and potassium in young men with and without a familial predisposition to hypertension

Parfrey, P. S., Condon, K., Wright, P., Vandenburg, M. J., Holly, J. M., Goodwin, F. J., Evans, S. J. & Ledingham, J. M., 1981, In : Lancet. 1, 8212, p. 113-7 5 p.

Research output: Contribution to journalArticle (Academic Journal)

44 Citations (Scopus)

Fetal haemoglobin in clinical severity of homozygous Sickle Cell Disease in early childhood

Stevens, MCG., Hayes, RJ., Serjeant, GR. & Vaidya, S., 1981, In : Journal of Pediatrics. 98, p. 37 - 41

Research output: Contribution to journalArticle (Academic Journal)

Impaired response of plasma renin activity to tilting after renal transplantation

Cunningham, J., Vandenburg, M. J., Holly, J. M. & Goodwin, F. J., 1981, In : Clinical Science. 61, 1, p. 69-73 5 p.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)

Observations on the natural history of dactylitis in homozygous Sickle Cell Disease

Stevens, MCG., Padwick, M. & Sergeant, GR., 1981, In : Clinical Paediatrics. 20, p. 311 - 317 7 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

Prolonged reduction in polymorphonuclear adhesion following oral colchicine

Kirwan, J., Cason, J. & Currey, H. L. F., 1 Jan 1981, In : Annals of the Rheumatic Diseases. 40, 6, p. 605-608 4 p.

Research output: Contribution to journalArticle (Academic Journal)

29 Citations (Scopus)

Re-analysis of data in two Lancet papers on the effect of dietary sodium and potassium on blood pressure

Holly, J. M., Goodwin, F. J., Evans, S. J., VandenBurg, M. J. & Ledingham, J. M., 1981, In : Lancet. 2, 8260-61, p. 1384-7 4 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

The effect of harmaline and related beta-carbolines on the acetylcholine-stimulated contractions of guinea-pig ileum

Hider, R. C., Smart, L. & Suleiman, M. S., 9 Apr 1981, In : European Journal of Pharmacology. 70, 4, p. 429-36 8 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)

The effect of harmaline and related harmala alkaloids on ouabain-stimulated contractions of the guinea-pig ileum

Hider, R. C., Smart, L. & Suleiman, M. S., 24 Apr 1981, In : European Journal of Pharmacology. 71, 1, p. 87-92 6 p.

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)

The in vivo metabolism of Althesin (alphaxalone + alphadolone acetate) in man

Holly, J. M., Trafford, D. J., Sear, J. W. & Makin, H. L., 1981, In : Journal of Pharmacy and Pharmacology. 33, 7, p. 427-33 7 p.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)
1982

Allopurinol effect on renal function in gout

Kirwan, J. R., 1 Jan 1982, In : Annals of the Rheumatic Diseases. 41, 4, p. 435-436 2 p.

Research output: Contribution to journalLetter (Academic Journal)

Clinical trials: Why not do them properly?

Kirwan, J. R., 1 Jan 1982, In : Annals of the Rheumatic Diseases. 41, 5, p. 551-552 2 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

Comparison of the cerebral function monitor and plasma concentrations of thiopentone and alphaxalone during total i.v. anaesthesia with repeated bolus doses of thiopentone and althesin

Frank, M., Savege, T. M., Leigh, M., Greenwood, J. & Holly, J. M., 1982, In : British Journal of Anaesthesia. 54, 6, p. 609-16 8 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

Modulation of adenylate cyclase by protein phosphorylation: effects of ACTH

Wiegant, V. M., Reul, J. M. & Gispen, W. H., 1982, In : Progress in Brain Research. 56, p. 397-404 8 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Sideroblastic anaemia with iron overload presenting as an arthropathy

Fitzcharles, M. A., Kirwan, J. R., Colvin, B. T. & Currey, H. L. F., 1 Jan 1982, In : Annals of the Rheumatic Diseases. 41, 1, p. 97-99 3 p.

Research output: Contribution to journalArticle (Academic Journal)

8 Citations (Scopus)
1983

Clinical judgement analysis. Practical application in rheumatoid arthritis

Kirwan, J. R., Chaput De Saintonge, D. M., Joyce, C. R. B. & Currey, H. L. F., 1 Jan 1983, In : British Journal of Rheumatology. 22, Suppl. 3, p. 18-23 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Clinical judgement analysis—practical application in rheumatoid arthritis

Kirwan, J. R., De Saintonge, D. M. C., Joyce, C. R. B. & Currey, H. L. F., 1 Jan 1983, In : Rheumatology. 22, p. 18-23 6 p.

Research output: Contribution to journalArticle (Academic Journal)

29 Citations (Scopus)

Clinical judgment in rheumatoid arthritis. I. Rheumatologists' opinions and the development of 'paper patients'

Kirwan, J. R., Chaput de Saintonge, D. M., Joyce, C. R. B. & Currey, H. L. F., 1 Jan 1983, In : Annals of the Rheumatic Diseases. 42, 6, p. 644-647 4 p.

Research output: Contribution to journalArticle (Academic Journal)

90 Citations (Scopus)

Clinical judgment in rheumatoid arthritis. II. Judging 'current disease activity' in clinical practice

Kirwan, J. R., Chaput de Saintonge, D. M., Joyce, C. R. B. & Currey, H. L. F., 1 Jan 1983, In : Annals of the Rheumatic Diseases. 42, 6, p. 648-651 4 p.

Research output: Contribution to journalArticle (Academic Journal)

61 Citations (Scopus)

Conclusion: A review of the symposium/workshop

Kirwan, J. R., De Saintonge, D. M. C., Joyce, C. R. B. & Currey, H. L. F., 1 Jan 1983, In : Rheumatology. 22, p. 95-97 3 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Crisis in rheumatology manpower

Kirwan, J. R., 1 Jan 1983, In : BMJ. 586

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)

Crisis in rheumatology manpower

Kirwan, J. R., 19 Feb 1983, In : BMJ (Clinical Research ed.). 286, 6365, 1 p.

Research output: Contribution to journalEditorial (Academic Journal)

4 Citations (Scopus)

Factors involved in the selective inhibition of monoamine oxidase

Tipton, K. F., O'Carroll, A. M., Mantle, T. J. & Fowler, C. J., 1983, In : Modern problems of pharmacopsychiatry. 19, p. 15-30 16 p.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)

Judging 'current disease activity' in rheumatoid arthritis. An international comparison

Kirwan, J. R., Bellamy, N., Condon, H., Buchanan, W. W. & Barnes, C. G., 1 Dec 1983, In : Journal of Rheumatology. 10, 6, p. 901-905 5 p.

Research output: Contribution to journalArticle (Academic Journal)

30 Citations (Scopus)

Plus ça change: predictors of birthweight in two national studies

Peters, TJ., Golding, J., Butler, NR., Fryer, JG., Lawrence, CJ. & Chamberlain, GVP., Nov 1983, In : BJOG: An International Journal of Obstetrics and Gynaecology. 90 (11), p. 1040 - 1045 6 p.

Research output: Contribution to journalArticle (Academic Journal)

46 Citations (Scopus)

Rheumatoid arthritis: Disease-modifying antirheumatic drugs

Kirwan, J. R. & Currey, H. L. F., 1 Dec 1983, In : Clinics in Rheumatic Diseases. 9, 3, p. 581-599 19 p.

Research output: Contribution to journalArticle (Academic Journal)

38 Citations (Scopus)

The deamination of dopamine by human brain monoamine oxidase. Specificity for the two enzyme forms in seven brain regions

O'Carroll, A. M., Fowler, C. J., Phillips, J. P., Tobbia, I. & Tipton, K. F., Apr 1983, In : Naunyn-Schmiedeberg's Archives in Pharmacology. 322, 3, p. 198-202 5 p.

Research output: Contribution to journalArticle (Academic Journal)

179 Citations (Scopus)

The effect of captopril and propranolol on the responses to posture and isometric exercise in patients with essential hypertension

Vandenburg, M. J., Holly, J. M., Goodwin, F. J., Sharman, V. L. & Marsh, F. P., 1983, In : European Journal of Clinical Pharmacology. 25, 6, p. 721-8 8 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)

The estimation of catecholamines in human plasma

Holly, J. M. & Makin, H. L., 1983, In : Analytical Biochemistry. 128, 2, p. 257-74 18 p.

Research output: Contribution to journalArticle (Academic Journal)

67 Citations (Scopus)

What makes a clinical trial report helpful? a preliminary analysis of rheumatologists' judgements

De Saintonge, D. M. C., Hattersley, L. A. & Kirwan, J. R., 1 Jan 1983, In : Rheumatology. 22, p. 59-66 8 p.

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)
1984

Clinical judgment in rheumatoid arthritis. III. British rheumatologists' judgments of 'change in response to therapy'

Kirwan, J. R., Chaput de Saintonge, D. M., Joyce, C. R. B. & Currey, H. L. F., 1 Jan 1984, In : Annals of the Rheumatic Diseases. 43, 5, p. 686-694 9 p.

Research output: Contribution to journalArticle (Academic Journal)

34 Citations (Scopus)

Clinical judgment in rheumatoid arthritis. IV Rheumatologists' assessments of disease remain stable over long periods

Kirwan, J. R. & Currey, H. L. F., 1 Jan 1984, In : Annals of the Rheumatic Diseases. 43, 5, p. 695-697 3 p.

Research output: Contribution to journalArticle (Academic Journal)

11 Citations (Scopus)

Delayed onset of regular respiration and subsequent development

Peters, TJ., Golding, J., Lawrence, CJ., Fryer, JG., Chamberlain, GVP. & Butler, NR., Apr 1984, In : Early Human Development. 9 (3), p. 225 - 239 15 p.

Research output: Contribution to journalArticle (Academic Journal)

10 Citations (Scopus)

Detection and enhancement of the hypnotic state in susceptible and resistant subjects

Griffiths, MJ. & Preece, AW., 1984, In : Journal of the Forensic Science Society. 24; 4, p. 359 - 359 1 p.

Research output: Contribution to journalArticle (Academic Journal)

Dielectric permittivity measurements of t-butyl compoundsa critical comparison with incoherent quasielastic neutronscattering results

Richardson, R. M. & Taylor, P., 1 Jan 1984, In : Molecular Physics. 52, 3, p. 525-540 16 p.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)