Research Output

2020

Association of combination statin and antihypertensive therapy with reduced Alzheimer’s disease and related dementia risk

Barthold, D., Joyce, G., Diaz Brinton, R., Wharton, W., Kehoe, P. G. & Zissimopoulos, J., 4 Mar 2020, In : PLoS ONE. 15, 3, 15 p., e0229541.

Research output: Contribution to journalArticle (Academic Journal)

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Association of radial artery graft vs saphenous vein graft with long-term cardiovascular outcomes among patients undergoing coronary artery bypass grafting: a systematic review and meta-analysis

Gaudino, M., Benedetto, U., Fremes, S. E., Ballman, K., Biondi-Zoccai, G., Sedrakyan, A., Nasso, G., Raman, J., Buxton, B., Hayward, P., Moat, N., Collins, P., Webb, C. A., Peric, M., Petrovic, I., Yoo, K. J., Hameed, I., Di Franco, A., Moscarelli, M., Speziale, G. & 4 others, Puskas, J. D., Girardi, L., Hare, D. & Taggart, D., 14 Jul 2020, In : JAMA - Journal of the American Medical Association. p. 179-187 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Associations between prenatal indicators of mechanical loading and proximal femur shape: findings from a population-based study in ALSPAC offspring

Frysz, M., Tobias, J. H., Lawlor, D. A., Aspden, R. M., Gregory, J. & Ireland, A., 30 Mar 2020, (Accepted/In press) In : Journal of Musculoskeletal and Neuronal Interactions.

Research output: Contribution to journalArticle (Academic Journal)

1 Downloads (Pure)

A systematic review of intervention studies demonstrates the need to develop a minimum set of indicators to report the presence of burn wound infection.

Davies, A. K., Spickett-Jones, F., Jenkins, A. T. A. & Young, A., 24 Apr 2020, In : Burns. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Attitudes to palliative care in patients with Neck-of-Femur fracture: A multi-centre survey

Harries, L., Moore, A., Kendall, C., Stanger, S., Stringfellow, T., Davies, A. & Kelly, M., 16 Apr 2020, In : Geriatric Orthopaedic Surgery & Rehabilitation. 11, 7 p.

Research output: Contribution to journalArticle (Academic Journal)

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A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

Szemes, M., Bellamy, J., Melegh, Z., Greenhough, A., Kollareddy, M., Catchpoole, D. & Malik, K., 23 Mar 2020, In : Cells. 9, 3, 18 p., 783.

Research output: Contribution to journalArticle (Academic Journal)

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Baseline Results: The Association between Cardiovascular Risk and Preclinical Alzheimer's Disease Pathology (ASCEND) Study

Kumar, V. V., Huang, H., Zhao, L., Verble, D. D., Nutaitis, A., Tharwani, S. D., Brown, A. L., Zetterberg, H., Hu, W., Shin, R., Kehoe, P. G., Quyyumi, A., Nocera, J., Kippels, A. & Wharton, W., 3 Apr 2020, In : Journal of Alzheimer's Disease. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

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Baseline self-report 'central mechanisms' trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort

Akin-Akinyosoye, K., Sarmanova, A., Fernandes, G. S., Frowd, N., Swaithes, L., Stocks, J., Valdes, A., McWilliams, D. F., Zhang, W., Doherty, M., Ferguson, E. & Walsh, D. A., 1 Feb 2020, In : Osteoarthritis and Cartilage. 28, 2, p. 173-181 9 p.

Research output: Contribution to journalArticle (Academic Journal)

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Baseline Serum HE4 But Not Tissue HE4 Expression Predicts Response to the Levonorgestrel-Releasing Intrauterine System in Atypical Hyperplasia and Early Stage Endometrial Cancer

Behrouzi, R., Ryan, N. A. J., Barr, C. E., Derbyshire, A. E., Wan, Y. L., Maskell, Z., Stocking, K., Pemberton, P. W., Bolton, J., McVey, R. J. & Crosbie, E. J., 23 Jan 2020, In : Cancers. 12, 2

Research output: Contribution to journalArticle (Academic Journal)

BCATC modulates crosstalk between the PIK/AKT and the RAS/ERK pathway regulating proliferation in triple negative breast cancer

Shafei, M., Forshaw, T., Davis, J., Flemban, A., Qualtrough, J. D., Dean, S., Perks, C. M., Dong, M., Newman, R. & Conway, M., 14 Apr 2020, (Accepted/In press) In : Oncotarget.

Research output: Contribution to journalArticle (Academic Journal)

BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease

Harris, M., El Hindy, M., Usmari-Moraes, M., Hudd, F., Shafei, M., Dong, M., Hezwani, M., Clark, P., House, M., Forshaw, T., Kehoe, P. & Conway, M. E., 23 Jan 2020, In : Free Radical Biology and Medicine.

Research output: Contribution to journalArticle (Academic Journal)

Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death

Hughes, C., Choi, M. L., Yi, J. H., Kim, S. C., Drews, A., George-Hyslop, P. S., Bryant, C., Gandhi, S., Cho, K. & Klenerman, D., 18 Feb 2020, In : Communications Biology. 3, 7 p., 79 (2020).

Research output: Contribution to journalArticle (Academic Journal)

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3 Citations (Scopus)
45 Downloads (Pure)

Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA.

Pooley, J., Rivers, C. A., Kilcooley, M., Paul, S. N., Cavga, A. D., Kershaw, Y. M., Muratcioglu, S., Gursoy, A., Keskin, O. & Lightman, S. L., 10 Jan 2020, In : PLoS ONE. 15, 1, 35 p., e0227520.

Research output: Contribution to journalArticle (Academic Journal)

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Bicuspid aortic valve repair with hemi-remodeling technique and external ring annuloplasty

Carlotta, B., Zakkar, M., Zacek, P., Palladino, M. & Lansac, E., 3 Jan 2020, In : Journal of Cardiac Surgery. 35, 1, p. 146-150 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Bilateral Acetabular Fractures: Mechanism, Fracture Patterns and Associated Injuries

Stevens, J. M., Shiels, S., Whitehouse, M. R., Ward, A. J., Chesser, T. J. & Acharya, M., Mar 2020, In : Journal of Orthopaedics. 18, p. 28-31 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Blood parameters measured on admission as predictors of outcome for COVID-19; a prospective UK cohort study

Arnold, D. T., Attwood, M., Barratt, S., Elvers, K., Morley, A., McKernon, J., Oates, A., Donald, C., Noel, A., MacGowan, A., Maskell, N. A. & Hamilton, F., 29 Jun 2020

Research output: Other contribution

Body composition after allogeneic hematopoietic cell transplantation / total body irradiation in children and young people: a restricted systematic review

Lorenc, A., Shield, J. P. H., Perry, R. E., Stevens, M. & CTYA HSCT Adipose and Muscle late effects working group, 18 Jul 2020, In : Journal of Cancer Survivorship. 19 p.

Research output: Contribution to journalArticle (Academic Journal)

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Bone Marrow as a Target and Accomplice of Vascular Complications in Diabetes

Santopaolo, M., Sambataro, M., Spinetti, G. & Madeddu, P., Mar 2020, In : Diabetes/Metabolism Research and Reviews. 36, S1, 6 p., e3240.

Research output: Contribution to journalReview article (Academic Journal)

Bone marrow fat: friend or foe in people with diabetes mellitus?

Santopaolo, M., Gu, Y., Spinetti, G. & Madeddu, P. R., 27 Apr 2020, In : Clinical Science. 134, 8, p. 1031 – 1048 18 p.

Research output: Contribution to journalReview article (Academic Journal)

Brain biopsy before or after treatment with corticosteroids

Rice, C. M., Renowden, S. A., Urankar, K., Love, S. & Scolding, N. J., 28 Apr 2020, In : Neuroradiology. 2 p.

Research output: Contribution to journalLetter (Academic Journal)

BRCA1 and BRCA2 pathogenic variant carriers and endometrial cancer risk: A cohort study

Kitson, S. J., Bafligil, C., Ryan, N. A. J., Lalloo, F., Woodward, E. R., Clayton, R. D., Edmondson, R. J., Bolton, J., Crosbie, E. J. & Evans, D. G., Sep 2020, In : European Journal of Cancer.

Research output: Contribution to journalArticle (Academic Journal)

Capturing remote disease activity – results of a 12-month clinical pilot of a smartphone app in NHS rheumatology clinics in Bristol

Hamann, P. D. H., Minaur, N., Tobias, J. H. & Clark, E. M., 7 Feb 2020, In : Rheumatology. 3 p., eaa015.

Research output: Contribution to journalLetter (Academic Journal)

Cardiorespiratory fitness is not associated with fracture risk in middle-aged men

Kunutsor, S. K., Mäkikallio, T. H., Voutilainen, A., Blom, A. W., Savonen, K. & Laukkanen, J. A., 23 Jul 2020, In : European Journal of Clinical Investigation. 5 p., e13360.

Research output: Contribution to journalLetter (Academic Journal)

Cardiovascular complications in COVID-19: A systematic review and meta-analysis

Kunutsor, S. K. & Laukkanen, J. A., 1 Aug 2020, In : Journal of Infection. 81, 2, p. e139-e141 3 p.

Research output: Contribution to journalLetter (Academic Journal)

Cathepsin C is a novel mediator of podocyte and renal injury induced by hyperglycemia

Audzeyenka, I., Rachubik, P., Rogacka, D., Typiak, M., Kulesza, T., Angielski, S., Rychłowski, M., Wysocka, M., Gruba, N., Lesner, A., Saleem, M. A. & Piwkowska, A., 1 Aug 2020, In : Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1867, 8, 118723.

Research output: Contribution to journalArticle (Academic Journal)

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Cementless unicompartmental knee replacement achieves better ten year clinical outcomes than Cemented: A systematic review

Mohammad, H. R., Bullock, G., Kennedy, J., Mellon, S., Murray, D. W. & Judge, A., 1 Jul 2020, In : Knee Surgery, Sports Traumatology, Arthroscopy. (2020), 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Cerebral venous sinus thrombosis associated with COVID-19

Thompson, A., Morgan, C. A. M., Smith, P., Jones, C., Ball, H. A., Coulthard, E. J., Moran, E., Szewczyk-Krolikowski, K. & Rice, C. M., 15 Sep 2020, (Accepted/In press) In : Practical Neurology.

Research output: Contribution to journalLetter (Academic Journal)

Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice

Pavlidis, I., Spiller, O. B., Sammut Demarco, G., MacPherson, H., Howie, S. E. M., Norman, J. E. & Stock, S. J., 10 Jan 2020, In : Nature Communications. 11, 12 p., 199 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
65 Downloads (Pure)

Characteristics of early Paget's disease in SQSTMI mutation carriers: baseline analysis of the ZIPP study cohort

Cronin, O., Subedi, D., Forsyth, L., Goodman, K., Lewis, S. C., Keerie, C., Walker, A., Porteous, M., Cetnarskyj, R., Ranganath, L. R., Selby, P., Hampson, G., Chandra, R., Ho, S., Tobias, J. H., Young-Min, S., McKenna, M. J., Crowley, R. K., Fraser, W. D., Tang, J. & 19 others, Gennari, L., Nuti, R., Brandi, M. L., Del Pino-Montes, J., Devogelaer, J-P., Durnez, A., Isaia, G. C., Di Stefano, M., Rubio, J. B., Guañabens, N., Seibel, M. J., Walsh, J. P., Kotowicz, M. A., Nicholson, G. C., Duncan, E. L., Major, G., Horne, A., Gilchrist, N. L. & Ralston, S. H., 16 Mar 2020, In : Journal of Bone and Mineral Research. 7 p.

Research output: Contribution to journalArticle (Academic Journal)

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Chronic comorbidities in children and adolescents with perinatally acquired HIV infection in sub-Saharan Africa in the era of antiretroviral therapy

Frigati, L., Ameyan, W., Cotton, M. F., Gregson, C. L., Hoare, J., Jao, J., Majonga, E., Myer, L., Penazzato, M., Rukuni, R., Rowland-Jones, S., Zar, H. J. & Ferrand, R. A., 30 Apr 2020, In : Lancet Child and Adolescent Health.

Research output: Contribution to journalArticle (Academic Journal)

Circulating BPIFB4 levels associate with and influence the abundance of reparative monocytes and macrophages in long living individuals

Ciaglia, E., Montella, F., Lopardo, V., Scala, P., Ferrario, A., Cattaneo, M., Carrizzo, A., Malovini, A., Madeddu, P. R., Vecchione, C. & Puca, A. A., 29 May 2020, In : Frontiers in Immunology. 11, 8 p., 1034.

Research output: Contribution to journalArticle (Academic Journal)

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Circulating MicroRNA-15a Associates With Retinal Damage in Patients With Early Stage Type 2 Diabetes

Sangalli, E., Tagliabue, E., La Sala, L., Pratichizzo, F., Uccellatore, A., Spada, D., Lorino, F., de Candia, P., Lupini, S., Cantone, L., Favero, C., Madeddu, P. R., Bollati, V., Genovese, S. & Spinetti, G., 23 Apr 2020, In : Frontiers in Endocrinology. 11, 8 p., 254.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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Clinical and Genetic Features in a Series of Eight Unrelated Patients with Neuropathy Due to Glycyl-tRNA Synthetase (GARS) Variants

Forrester, N., Rattihalli, R., Horvath, R., Maggi, L., Manzur, A., Fuller, G., Gutowski, N., Rankin, J., Dick, D., Buxton, C., Greenslade, M. & Majumdar, A., 20 Mar 2020, In : Journal of neuromuscular diseases. 7, 2, p. 137-143 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Clinical and laboratory characteristics in juvenile-onset Systemic Lupus Erythematosus across age groups

Massias, J. S., Smith, E. M. D., Ramanan, A. V. & al., E., 1 Apr 2020, In : Lupus. 29, 5, p. 474-481 8 p.

Research output: Contribution to journalArticle (Academic Journal)

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Clinical efficacy and mechanistic evaluation of Eplerenone for central serous chorio-retinopathy – the VICI randomised trial

Lotery, A., Sivaprasad, S., O'Connell, A. J., Harris, R. A., Culliford, L. A., Cree, A., Madhusudhan, S., Griffiths, H., Ellis, L. A., Chakravarthy, U., Peto, T., Rogers, C. A. & Reeves, B. C., 8 Jun 2020, (Accepted/In press) In : Health Technology Assessment.

Research output: Contribution to journalArticle (Academic Journal)

Clinical presentation and proteomic signature of patients with TANGO2 mutations

Mingirulli, N., Pyle, A., Hathazi, D., Alston, C. L., Kohlschmidt, N., O'Grady, G., Waddell, L., Evesson, F., Cooper, S. B. T., Turner, C., Duff, J., Topf, A., Yubero, D., Jou, C., Nascimento, A., Ortez, C., García-Cazorla, A., Gross, C., O'Callaghan, M., Santra, S. & 23 others, Preece, M. A., Champion, M., Korenev, S., Chronopoulou, E., Anirban, M., Pierre, G., McArthur, D., Thompson, K., Navas, P., Ribes, A., Tort, F., Schlüter, A., Pujol, A., Montero, R., Sarquella, G., Lochmüller, H., Jiménez-Mallebrera, C., Taylor, R. W., Artuch, R., Kirschner, J., Grünert, S. C., Roos, A. & Horvath, R., 3 Mar 2020, In : Journal of Inherited Metabolic Disease. 43, 2, p. 297-308 12 p.

Research output: Contribution to journalArticle (Academic Journal)

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Closed-circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects

Dingley, J., Okano, S., Lee-Kelland, R., Scull-Brown, E., Thoresen, M. & Chakkarapani, E., 21 Jan 2020, In : PLoS ONE. 15, 1, 18 p.

Research output: Contribution to journalArticle (Academic Journal)

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CNS demyelination associated with immune dysregulation and a novel CLTA-4 variant

Kaninia, S., Grammatikos, A., Urankar, K., Renowden, S., Patel, N., Gompels, M. & Rice, C. M., 14 Sep 2020, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalLetter (Academic Journal)

Cognitive impairment in COPD: an often overlooked co-morbidity

Higbee, D. H. & Dodd, J. W., 26 Aug 2020, In : Expert Review of Respiratory Medicine. 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Cohort profile: the Oxford Parkinson's Disease Centre Discovery Cohort MRI substudy (OPDC-MRI)

Griffanti, L., Klein, J. C., Szewczyk-Krolikowski, K., Menke, R. A. L., Rolinski, M., Barber, T. R., Lawton, M., Evetts, S. G., Begeti, F., Crabbe, M., Rumbold, J., Wade-Martins, R., Hu, M. T. & Mackay, C., 13 Aug 2020, In : BMJ Open. 10, 8, p. e034110

Research output: Contribution to journalArticle (Academic Journal)

Combined degenerative mitral valve and coronary surgery: early outcomes and 10- year survival

Bruno, V. D., Zakkar, M., Guida, G., Rapetto, F., Rathore, A. & Ascione, R., 8 Apr 2020, In : Annals of Thoracic Surgery.

Research output: Contribution to journalArticle (Academic Journal)

Commentary: To underfit and to overfit the data. This is the dilemma

Benedetto, U. & Dimagli, A., 11 Jan 2020, In : Journal of Thoracic and Cardiovascular Surgery. 2 p.

Research output: Contribution to journalEditorial (Academic Journal)