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2020

Abnormal scaffold attachment factor 1 expression and localisation in spinocerebellar ataxias and huntington’s chorea

Buckner, N., Kemp, K. C., Scott, H. L., Shi, G., Rivers, C. A., Gialeli, A., Wong, L-F., Cordero Llana, O., Allen, N., Wilkins, A. & Uney, J. B., 24 Jun 2020, In : Brain Pathology. 15 p.

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A board level intervention to develop organisation-wide quality improvement strategies: cost-consequences analysis in 15 healthcare organisations

Capelas Barbosa, E., Jones, L., Pomeroy, L., Robert, G., Burnett, S., Anderson, J., Morris, S. & Fulop, N., 3 Jun 2020, (Accepted/In press) In : Internacional Journal of Health Policy and Management.

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Accuracy of clinical coding of pleural empyema: A validation study

Hamilton, F. & Arnold, D., 1 Feb 2020, In : Journal of Evaluation in Clinical Practice. 26, 1, p. 79-80 2 p.

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ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

Evans, C., Miners, J. S., Piva, G., Willis, C. L., Heard, D. M., Kidd, E. J., Good, M. & Kehoe, P. G., 25 Jan 2020, In : Acta Neuropathologica. 18 p.

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A Critical Role for Perivascular Cells in Amplifying Vascular Leakage Induced by Dengue Virus Non-Structural Protein 1

Cheung, Y. P., Mastrullo, V., Maselli, D., Butsabong, T., Madeddu, P. R., Maringer, K. & Campagnolo, P., 5 Aug 2020, In : mSphere. 5, 4, 11 p., e00258-20.

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Activation of bone marrow adaptive immunity in type 2 diabetes: rescue by co-stimulation modulator Abatacept

Santopaolo, M., Sullivan, N., Thomas, A. C., Alvino, V. V., Nicholson, L. B., Gu, Y., Spinetti, G., Kallikourdis, M., Blom, A. W. & Madeddu, P. R., 3 Jul 2020, (Submitted) In : Diabetologia.

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Activation of C-Reactive Protein Proinflammatory Phenotype in the blood retinal barrier in vitro: Implications for Age-related Macular Degeneration

Romero-Vázquez, S., Adán, A., Figueras-Roca, M., Llorenç, V., Slevin, M., Vilahur, G., Badimon, L., Dick, A. D. & Molins, B., 16 Jul 2020, In : Aging. 12, 19 p.

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Agreement was moderate between data-based and opinion-based predictions of biases affecting randomized trials within meta-analyses

Turner, R. M., Rhodes, K. M., Jones, H. E., Higgins, J. P. T., Haskins, J., Whiting, P. F., Hróbjartsson, A., Caldwell, D. M., Morris, R. W., Reeves, B. C., Worthington, H., Boutron, I. & Savović, J., 13 May 2020, In : Journal of Clinical Epidemiology. 125, p. 16-25 10 p.

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Agrin-mediated cardiac regeneration: some open questions

Bigotti, M. G., Skeffington, K. L., Jones, F. P., Caputo, M. & Brancaccio, A., 16 Jun 2020, In : Frontiers in Bioengineering and Biotechnology. 8, 8 p., 594.

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A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly

Anton, Z., Betin, V. M. S., Simonetti, B., Traer, C. J., Attar, N., Cullen, P. J. & Lane, J. D., 15 Jul 2020, In : Journal of Cell Science. 133, 14, 38 p., jcs246306.

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Airway management for dental clearance in a preschool child: A UK survey

Shrimpton, A. J. & Gill, H., 16 Apr 2020, (Accepted/In press) In : Paediatric Anaesthesia.

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Alemtuzumab-related eosinophilic central nervous system vasculitis

Leach, O. A., Hilton, D. A., Adams, W., Love, S. & Straukiene, A., 21 Feb 2020, In : Multiple Sclerosis Journal. 4 p.

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Alendronate use and bone mineral density gains in women with moderate-severe (stages 3B-5) chronic kidney disease: an open cohort multivariable and propensity score analysis from Funen, Denmark

Ali, M. S., Ernst, M., Robinson, D. E., Caskey, F., Arden, N. K., Ben-Shlomo, Y., Nybo, M., Rubin, K. H., Judge, A., Cooper, C., Javaid, M. K., Hermann, A. P. & Prieto-Alhambra, D., 1 Jun 2020, In : Archives of Osteoporosis. 15, 1, 12 p., 81 (2020) .

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A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

Stathakos, P., Jiménez Moreno, N., Crompton, L. A., Nistor, P. A., Badger, J. L., Barbuti, P. A., Kerrigan, T. L., Randall, A. D., Caldwell, M. A. & Lane, J. D., 14 Apr 2020, In : Autophagy. 17 p.

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Analysing Neat Biofluids Obtained During Cardiac Surgery Using Nanoparticle Tracking Analysis: Methodological Considerations

Shearn, A. I. U., Aday, S., Ben-Aicha, S., Carnell-Morris, P., Siupa, A., Angelini, G. D., Clayton, A., Boulanger, C. M., Punjabi, P., Emanueli, C. & Biglino, G., 24 Apr 2020, (Accepted/In press) In : Frontiers in Cell and Developmental Biology. 8, 14 p., 367.

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A Nationwide Survey of UK cardiac surgeons’ view on clinical decision making during the COVID-19 pandemic

Benedetto, U., Goodwin, A., Kendall, S., Uppal, R. & Akowuah, E., 20 May 2020, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

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A new pedigree with thrombomodulin-associated coagulopathy in which delayed fibrinolysis is partially attenuated by co-inherited TAFI deficiency

Westbury, S. K., Whyte, C. S., Stephens, J., Downes, K., Turro, E., Claesen, K., Mertens, J., Hendriks, D., Latif, A-L., Leishman, E., NIHR BioResource, Mutch, N. J., Tait, C. R. & Mumford, A. D., 7 Jul 2020, In : Journal of Thrombosis and Haemostasis. 6 p.

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An information theoretic approach to insulin sensing by human kidney podocytes

Pope, R. JP., Garner, K. L., Voliotis, M., Lay, A. C., Betin, V. MS., Tsaneva-Atanasova, K., Welsh, G. I., Coward, R. JM. & McArdle, C. A., 1 Aug 2020, In : Molecular and Cellular Endocrinology. 110976.

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Anomalous Left Atrial Drainage of the Vena Cava in an Adult French Bulldog

Borgeat, K., Lyraki, M., Keyte, S., Roper, D., Caputo, M. & Chanoit, G., 16 Apr 2020, In : CASE: Cardiovascular Imaging Case Reports. 6 p.

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AntiThrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC): study design and methodology for an international, adaptive Bayesian randomized controlled trial

Houston, B. L., Lawler, P. R., Goligher, EC., Farkouh, M. E., Bradbury, C. A., Carrier, M., Dzavik, V., Fergusson, D., Fowler, R. A., Galanaud, J. P., Gross, P., McDonald, E. G., Husain, M., Khan, S. R., Kumar, A., Marshall, J., Murthy, S., Slutsky, A., Turgeon, A. F., Berry, S. & 4 others, Rosenson, R. S., Escobedo, G., Nicolau, J. C. & Zarychanski, R., 20 Jun 2020, (Accepted/In press) In : Clinical Trials.

Research output: Contribution to journalArticle (Academic Journal)

An unusual case of Mycobacterium chelonae infection

Shorrocks, R., Hayward, S. J. L. & Moran, E., 28 Feb 2020, In : Access Microbiology.

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A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling

Rodriguez, B. A. T., Bhan, A., Beswick, A., Elwood, P. C., Niiranen, T. J., Salomaa, V., Trégouët, D-A., Morange, P-E., Civelek, M., Ben-Shlomo, Y., Schlaeger, T., Chen, M-H. & Johnson, A. D., 9 Jul 2020, In : American Journal of Human Genetics.

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APOL1 kidney-risk variants induce mitochondrial fission

Ma, L., Saleem, M. & al., E., 8 Feb 2020, (Accepted/In press) In : Kidney International.

Research output: Contribution to journalArticle (Academic Journal)

A Rapid Robust Method for Subgrouping Non-NF2 Meningiomas According to Genotype and Detection of Lower Levels of M2 Macrophages in AKT1 E17K Mutated Tumours

Adams, C. L., Ercolano, E., Ferluga, S., Sofela, A., Dave, F., Negroni, C., Kurian, K. M., Hilton, D. A. & Hanemann, C. O., 13 Feb 2020, In : International Journal of Molecular Sciences. 21, 4

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A real-time electronic symptom monitoring system for patients after discharge following surgery: a pilot study in cancer-related surgery

Richards, H. S., Blazeby, J. M., Portal, A., Harding, R., Reed, T., Lander, T., Chalmers, K. A., Carter, R., Absolom, K., Singhal, R., Velikova, G. & Avery, K. N. L., 10 Jun 2020, In : BMC Cancer. 20, 17 p., 543 (2020).

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Areas of agreement in the management of childhood non-infectious chronic anterior uveitis in the UK

POIG Uveitis Delphi Group, 1 Jan 2020, In : British Journal of Ophthalmology. 104, 1, p. 11-16 6 p.

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A review of registry research from 2019

Evans, J. T. & Whitehouse, M. R., 1 Apr 2020, In : BJ360. 9, 2

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A role for NPY-NPY2R signaling in albuminuric kidney disease

Lay, A. C., Barrington, A. F., Hurcombe, J. A., Ramnath, R. D., Graham, M., Lewis, P. A., Wilson, M. C., Heesom, K. J., Butler, M. J., Perrett, R. M., Neal, C. R., Herbert, E., Mountjoy, E., Atan, D., Nair, V., Ju, W., Nelson, R. G., Kretzler, M., Satchell, S. C., McArdle, C. A. & 2 others, Welsh, G. I. & Coward, R. J. M., 19 Jun 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 12 p., 202004651.

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Assessing the construct validity and responsiveness of Preference Based Measures (PBMs) in cataract surgery patients

Breheny, K., Hollingworth, W., Kandiyali, R., Dixon, P., Loose, A., Craggs, P., Grzeda, M. & Sparrow, J., 20 Feb 2020, In : Quality of Life Research. 12 p.

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Assessment of patients with lower urinary tract symptoms where an undiagnosed neurological disease is suspected: report from an International Continence Society consensus working group

Roy, H. A., Nettleton, J., Blain, C., Dalton, C., Farhan, B., Fernandes, A., Georgopoulos, P., Klepsch, S., Lavelle, J., Martinelli, E., Panicker, J. N., Radoja, I., Rapidi, C-A., Silva, R. P. E., Tudor, K., Wagg, A. S. & Drake, M. J., 16 Jul 2020, (Accepted/In press) In : Neurourology and Urodynamics.

Research output: Contribution to journalArticle (Academic Journal)

Assessment of the most impactful combination of factors associated with nocturia and to define nocturnal polyuria by multivariate modelling

Olesen, T., Paul, J., Gramme, P., Drake, M. J., Vande Walle, J. & Everaert, K., 16 Jul 2020, In : Journal of Clinical Medicine. 9, 7, 10 p., 2262.

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Association between estimated pulse wave velocity and the risk of stroke in middle-aged men

Jae, S. Y., Heffernan, K., Kurl, S., Kunutsor, S. K. & Laukkanen, J. A., 6 Aug 2020, (Accepted/In press) In : International Journal of Stroke.

Research output: Contribution to journalArticle (Academic Journal)

Association between genetic polymorphisms and endometrial cancer risk: a systematic review

Bafligil, C., Thompson, D. J., Lophatananon, A., Smith, M. J., Ryan, N. A., Naqvi, A., Evans, D. G. & Crosbie, E. J., 17 Feb 2020, In : Journal of Medical Genetics.

Research output: Contribution to journalArticle (Academic Journal)

Association of combination statin and antihypertensive therapy with reduced Alzheimer’s disease and related dementia risk

Barthold, D., Joyce, G., Diaz Brinton, R., Wharton, W., Kehoe, P. G. & Zissimopoulos, J., 4 Mar 2020, In : PLoS ONE. 15, 3, 15 p., e0229541.

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Association of radial artery graft vs saphenous vein graft with long-term cardiovascular outcomes among patients undergoing coronary artery bypass grafting: a systematic review and meta-analysis

Gaudino, M., Benedetto, U., Fremes, S. E., Ballman, K., Biondi-Zoccai, G., Sedrakyan, A., Nasso, G., Raman, J., Buxton, B., Hayward, P., Moat, N., Collins, P., Webb, C. A., Peric, M., Petrovic, I., Yoo, K. J., Hameed, I., Di Franco, A., Moscarelli, M., Speziale, G. & 4 others, Puskas, J. D., Girardi, L., Hare, D. & Taggart, D., 14 Jul 2020, In : JAMA - Journal of the American Medical Association. p. 179-187 9 p.

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Associations between prenatal indicators of mechanical loading and proximal femur shape: findings from a population-based study in ALSPAC offspring

Frysz, M., Tobias, J. H., Lawlor, D. A., Aspden, R. M., Gregory, J. & Ireland, A., 30 Mar 2020, (Accepted/In press) In : Journal of Musculoskeletal and Neuronal Interactions.

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A systematic review of intervention studies demonstrates the need to develop a minimum set of indicators to report the presence of burn wound infection.

Davies, A. K., Spickett-Jones, F., Jenkins, A. T. A. & Young, A., 24 Apr 2020, In : Burns. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Attitudes to palliative care in patients with Neck-of-Femur fracture: A multi-centre survey

Harries, L., Moore, A., Kendall, C., Stanger, S., Stringfellow, T., Davies, A. & Kelly, M., 16 Apr 2020, In : Geriatric Orthopaedic Surgery & Rehabilitation. 11, 7 p.

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A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma

Szemes, M., Bellamy, J., Melegh, Z., Greenhough, A., Kollareddy, M., Catchpoole, D. & Malik, K., 23 Mar 2020, In : Cells. 9, 3, 18 p., 783.

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Baseline Results: The Association between Cardiovascular Risk and Preclinical Alzheimer's Disease Pathology (ASCEND) Study

Kumar, V. V., Huang, H., Zhao, L., Verble, D. D., Nutaitis, A., Tharwani, S. D., Brown, A. L., Zetterberg, H., Hu, W., Shin, R., Kehoe, P. G., Quyyumi, A., Nocera, J., Kippels, A. & Wharton, W., 3 Apr 2020, In : Journal of Alzheimer's Disease. 9 p.

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Baseline self-report 'central mechanisms' trait predicts persistent knee pain in the Knee Pain in the Community (KPIC) cohort

Akin-Akinyosoye, K., Sarmanova, A., Fernandes, G. S., Frowd, N., Swaithes, L., Stocks, J., Valdes, A., McWilliams, D. F., Zhang, W., Doherty, M., Ferguson, E. & Walsh, D. A., 1 Feb 2020, In : Osteoarthritis and Cartilage. 28, 2, p. 173-181 9 p.

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Baseline Serum HE4 But Not Tissue HE4 Expression Predicts Response to the Levonorgestrel-Releasing Intrauterine System in Atypical Hyperplasia and Early Stage Endometrial Cancer

Behrouzi, R., Ryan, N. A. J., Barr, C. E., Derbyshire, A. E., Wan, Y. L., Maskell, Z., Stocking, K., Pemberton, P. W., Bolton, J., McVey, R. J. & Crosbie, E. J., 23 Jan 2020, In : Cancers. 12, 2

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BCATC modulates crosstalk between the PIK/AKT and the RAS/ERK pathway regulating proliferation in triple negative breast cancer

Shafei, M., Forshaw, T., Davis, J., Flemban, A., Qualtrough, J. D., Dean, S., Perks, C. M., Dong, M., Newman, R. & Conway, M., 14 Apr 2020, (Accepted/In press) In : Oncotarget.

Research output: Contribution to journalArticle (Academic Journal)

BCAT-induced autophagy regulates Aβ load through an interdependence of redox state and PKC phosphorylation-implications in Alzheimer's disease

Harris, M., El Hindy, M., Usmari-Moraes, M., Hudd, F., Shafei, M., Dong, M., Hezwani, M., Clark, P., House, M., Forshaw, T., Kehoe, P. & Conway, M. E., 23 Jan 2020, In : Free Radical Biology and Medicine.

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Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death

Hughes, C., Choi, M. L., Yi, J. H., Kim, S. C., Drews, A., George-Hyslop, P. S., Bryant, C., Gandhi, S., Cho, K. & Klenerman, D., 18 Feb 2020, In : Communications Biology. 3, 7 p., 79 (2020).

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Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA.

Pooley, J., Rivers, C. A., Kilcooley, M., Paul, S. N., Cavga, A. D., Kershaw, Y. M., Muratcioglu, S., Gursoy, A., Keskin, O. & Lightman, S. L., 10 Jan 2020, In : PLoS ONE. 15, 1, 35 p., e0227520.

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Bicuspid aortic valve repair with hemi-remodeling technique and external ring annuloplasty

Carlotta, B., Zakkar, M., Zacek, P., Palladino, M. & Lansac, E., 3 Jan 2020, In : Journal of Cardiac Surgery. 35, 1, p. 146-150 5 p.

Research output: Contribution to journalArticle (Academic Journal)