Bristol Medical School

2024

AlcoWatch - Exploring the feasibility of using smartwatch-based Ecological Momentary Assessment for high temporal density longitudinal measurement of alcohol use

Stone, C. J., Adams, S., Wootton, R. E. & Skinner, A. L., 12 Jun 2024, (Submitted) JMIR Preprints.

Research output: Working paper › Preprint

Direct and indirect genetic pathways between parental neuroticism and offspring emotional problems across development: evidence from 7 cohorts across 5 European nations

Sallis, H. M., Costantini, I., Chuong, M., Kantojärvi, K., Wootton, R. E., Jones, H. J., Sirignano, L., Frank, J., Streit, F., Witt, S. H., Zillich, L., Gilles, M., Ask, H., Kwong, A. S. F., Adams, M. J., Tilling, K. M., Lawlor, D. A., Timpson, N. J., Paunio, T. & Havdahl, K. A. & 4 others, McIntosh, A. M., Stein, A., James, D. & Pearson, R. M., 2024, (Submitted).

Research output: Working paper › Preprint

Empirically assessing the plausibility of unconfoundedness in observational studies

Hartwig, F. P., Tilling, K. & Smith, G. D., 15 Feb 2024, 35 p.

Research output: Working paper › Preprint

Open Access

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Evaluating the feasibility and acceptability of a smartwatch-based smoking relapse intervention ('StopWatch')

Stone, C. J., Essery, R., Matthews, J., Naughton, F., Munafo, M. R., Attwood, A. S. & Skinner, A. L., 1 Feb 2024, (Submitted) JMIR Preprints.

Research output: Working paper › Preprint

Role of Inflammation in Depressive and Anxiety Disorders, Affect, and Cognition: Genetic and Non-Genetic Findings in the Lifelines Cohort Study.

Giollabhui, N. M., Slaney, C., Hemani, G., Foley, E. M., Most, P. J. V. D., Nolte, I. M., Snieder, H., Smith, G. D., Khandaker, G. & Hartman, C., 19 Apr 2024, medRxiv.

Research output: Working paper › Preprint

Valid Conformal Prediction for Dynamic GNNs

Davis, E., Gallagher, I., Lawson, D. J. & Rubin-Delanchy, P., 29 May 2024, arXiv.org.

Research output: Working paper › Preprint

Open Access

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2023

Altered IL-6 signalling and risk of tuberculosis disease: a meta-analysis and Mendelian randomisation study

International Host TB Genetics Consortium, 8 Feb 2023, (medRxiv).

Research output: Working paper › Preprint

Compositional Fusion of Signals in Data Embedding

Guo, Z., Xu, Z., Lewis, M. & Cristianini, N., 18 Nov 2023, 19 p.

Research output: Working paper › Preprint

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Conventional and Bayesian workflows for clinical prediction modelling of severe Covid-19 outcomes based on clinical biomarker test results: LabMarCS: Laboratory Markers of COVID-19 Severity - Bristol Cohort

Sullivan, B., Barker, E., Williams, P., MacGregor, L., Bhamber, R., Thomas, M., Gurney, S., Hyams, C., Whiteway, A., Cooper, J., McWilliams, C., Turner, K., Dowsey, A. & Albur, M., 26 Apr 2023, 20 p.

Research output: Working paper › Preprint

Open Access

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Genetic meta-analysis of levodopa induced dyskinesia in Parkinson's disease

Martinez-Carrasco, A., Real, R., Lawton, M., Iwaki, H., Tan, M. M. X., Wu, L., Williams, N. M., Carroll, C., Hu, M. T. M., Grosset, D. G., Hardy, J., Ryten, M., Foltynie, T., Ben-Shlomo, Y., Shoai, M. & Morris, H. R., 30 May 2023, (medRxiv).

Research output: Working paper › Preprint

Rare disease gene association discovery from burden analysis of the 100,000 Genomes Project data

Cipriani, V., Vestito, L., Magavern, E. F., Jacobsen, J. O., Arno, G., Behr, E. R., Benson, K. A., Bertoli, M., Bockenhauer, D., Bowl, M. R., Burley, K., Chan, L. F., Chinnery, P., Conlon, P., Costa, M., Davidson, A. E., Dawson, S. J., Elhassan, E., Flanagan, S. E. & Futema, M. & 41 others, Gale, D. P., García-Ruiz, S., Corcia, C. G., Griffin, H. R., Hambleton, S., Hicks, A. R., Houlden, H., Houlston, R. S., Howles, S. A., Kleta, R., Lekkerkerker, I., Lin, S., Liskova, P., Mitchison, H., Morsy, H., Mumford, A. D., Newman, W. G., Neatu, R., O'Toole, E. A., Ong, A. C., Pagnamenta, A. T., Rahman, S., Rajan, N., Robinson, P. N., Ryten, M., Sadeghi-Alavijeh, O., Sayer, J. A., Shovlin, C. L., Taylor, J. C., Teltsh, O., Tomlinson, I., Tucci, A., Turnbull, C., van Eerde, A. M., Ware, J. S., Watts, L. M., Webster, A. R., Westbury, S. K., Zheng, S. L., Caulfield, M. & Smedley, D., 21 Dec 2023.

Research output: Working paper › Preprint

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2022

Effectiveness of BNT162b2 booster doses in England: an observational study in OpenSAFELY-TPP

Hulme, W. J., Williamson, E. J., Horne, E., Green, A. C., Nab, L., Keogh, R., Parker, E. P., Walker, V. M., Palmer, T. M., Curtis, H. J., Wiedemann, M., Cunningham, C., Walker, A. J., Fisher, L., MacKenna, B., Rentsch, C. T., Schultze, A., Bhaskaran, K., Tazare, J. & Tomlinson, L. A. & 24 others, McDonald, H. I., Morton, C. E., Croker, R., Andrews, C. D., Hopcroft, L. E., Park, R. Y., Massey, J., Mehrkar, A., Morley, J., Bacon, S. C., Evans, D., Inglesby, P., Hickman, G., Davy, S., Dillingham, I., Ward, T., Mahalingasivam, V., Zheng, B., Douglas, I. J., Evans, S. J., Bates, C., Sterne, J. A., Hernan, M. A. & Goldacre, B., 6 Jun 2022, (E-pub ahead of print) (medRxiv).

Research output: Working paper › Preprint

Examining risk factors for weight change during midlife: A Mendelian randomization study

Power, G. M., Tyrrell, J., Gkatzionis, A., Fang, S., Heron, J. E., Davey Smith, G. & Richardson, T. G., 29 Dec 2022, medRxiv, (medRxiv).

Research output: Working paper › Preprint

Familial Associations in Bone and Muscle Health in the Hertfordshire Intergenerational Study

Pearse, C., Fuggle, N. R., Ó Breasail, M., Clynes, M., Bevilacqua, G., Carter, S., Cooper, C., Harvey, N., Dennison, E. M. & Ward, K. A., 2022, (Unpublished) (SSRN Electronic Journal).

Research output: Working paper › Preprint

Integrating Mendelian randomization and literature-mined evidence for breast cancer risk factors

Vabistsevits, M., Robinson, T., Elsworth, B., Liu, Y. & Gaunt, T., 22 Jul 2022.

Research output: Working paper › Preprint

Neutrophils in severe COVID-19 are characterized by a hyperactive immature state and maintained CXCR2 expression

Hyams, C., 2022, (medRxiv).

Research output: Working paper › Preprint

Process evaluation protocol for the SLEEP study: a hybrid digital CBT-I intervention for working people with insomnia

Hurley-Wallace, A., Moukhtarian, T., Patel, K., Toro, C., Russel, S., Daley, G., Walasek, L., Tang, N. K. Y. & Meyer, C., 4 Mar 2022.

Research output: Working paper › Preprint

Open Access

Radiological follow-up of adults hospitalised with pneumonia and SARS-CoV-2 infection, in Bristol UK, during the COVID19 pandemic

Ruffino, G., Williams, R. L., Barratt, S. & Hyams, C., 5 Jan 2022.

Research output: Working paper › Preprint

Re-validating the "stopWatch" smartwatch-based system for passive detection of cigarette smoking

Stone, C. J., Attwood, A. S., Munafo, M. R. & Skinner, A. L., 21 Sept 2022, (PsyArXiv).

Research output: Working paper › Preprint

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The effect of genetically proxied IL-6 signalling on severe malaria: A Mendelian randomisation analysis

Hamilton, F. W., Mitchell, R. E., Constantinescu, A.-E. W., Hughes, D. A., Cunnington, A., Ghazal, P. & Timpson, N. J., 1 Nov 2022, p. 2022.11.04.22281934, (medRxiv).

Research output: Working paper › Preprint

Open Access

The effects of delay on the HKB model of human motor coordination

Allen, L. I., Molnar, T. G., Dombovari, Z. & Hogan, S. J., 2 Nov 2022.

Research output: Working paper › Preprint

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Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: Findings from a Mendelian randomisation study

Hamilton, F. W., Thomas, M., Arnold, D. T., Palmer, T. M., Moran, E., Mentzer, A. J., Maskell, N. A., Baillie, J. K., Summers, C., Hingorani, A. D., MacGowan, A. P., Khandaker, G. M., Mitchell, R. E., Davey Smith, G., Ghazal, P. & Timpson, N. J., 15 Jul 2022, (E-pub ahead of print) p. 2022.07.14.22277638, (medRxiv).

Research output: Working paper › Preprint

Treatment group outcome variance difference after dropout as an indicator of missing-not-at-random bias in randomized clinical trials

Hazewinkel, A.-D., Tilling, K., Wade, K. H. & Palmer, T., 18 Apr 2022, (E-pub ahead of print) p. 2022.04.15.22273918, (medRxiv).

Research output: Working paper › Preprint

Waning effectiveness of BNT162b2 and ChAdOx1 COVID-19 vaccines over six months since second dose: a cohort study using linked electronic health records

Horne, E. M., Hulme, W. J., Keogh, R. H., Palmer, T. M., Williamson, E. J., Parker, E. P., Green, A., Walker, V., Walker, A. J., Curtis, H., Fisher, L., MacKenna, B., Croker, R., Hopcroft, L., Park, R. Y., Massey, J., Morely, J., Mehrkar, A., Bacon, S. & Evans, D. & 9 others, Inglesby, P., Morton, C. E., Hickman, G., Davy, S., Ward, T., Dillingham, I., Goldacre, B., Hernan, M. A. & Sterne, J. A., 1 Jan 2022, p. 2022.03.23.22272804, (medRxiv).

Research output: Working paper › Preprint

2021

Limited impact of contact tracing in a University setting for COVID-19 due to asymptomatic transmission and social distancing

Stocks, D. A., Nixon, E. J., Trickey, A. J. W., Homer, M. E. & Brooks Pollock, E., 2021, (medRxiv).

Research output: Working paper › Preprint

Mental Health Intergenerational Transmission (MHINT) Process Manual

Costantini, I., Cordero, M., Campbell, A., Burgess, R. J., Glen, K., Moraitopoulou, G., Paul, E., Bornstein, M. H., Culpin, I. & Pearson, R. M., 13 Jul 2021, OSF, Moscow.

Research output: Working paper › Preprint

Open Access

Multilevel models with random residual variances for joint modelling school value-added effects on the mean and variance of student achievement

Leckie, G., Parker, R., Goldstein, H. & Tilling, K., 5 Oct 2021.

Research output: Working paper › Preprint

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Towards a molecular mechanism underlying mitochondrial protein import through the 2 TOM-TIM23 complexes

Ford, H. C., Allen, W. J., C. Pereira, G., Liu, X., Dillingham, M. S. & Collinson, I. R., 31 Aug 2021, (bioRxiv).

Research output: Working paper › Preprint

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Trajectories of child emotional and behavioural difficulties before and during the COVID-19 pandemic in a longitudinal UK cohort

Paul, E., Kounali, D.-Z., Kwong, A. S. F., Smith, D., Costantini, I., Lawlor, D. A., Sayal, K. S., Bould, H. E., Timpson, N. J., Northstone, K., Lewcock, M., Tilling, K. M. & Pearson, R. M., 2021, (Submitted).

Research output: Working paper › Preprint

Why do hippocampal mossy cells matter? It depends on the frequency and context

Kolaric, K., Strauch, C., Li, Y., Woods, S. M., Lopes, M. A., Sivarajah, N., Teixeira, C. M., Lerch, J., Frankland, P. W., Henkelman, M., Bortolotto, Z. A., Warburton, C., Bashir, Z. I., Vaughan, D. M. & Atan, D., 6 Dec 2021, (Submitted) bioRxiv.org, p. 1-30, 30 p.

Research output: Working paper › Preprint

2020

On the derivation of the renewal equation from an age-dependent branching process: an epidemic modelling perspective

Mishra, S., Berah, T., Mellan, T. A., Unwin, H. J. T., Vollmer, M. A., Parag, K. V., Gandy, A., Flaxman, S. & Bhatt, S., 30 Jun 2020.

Research output: Working paper › Preprint

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Qualitative Evaluation of Web-Based Digital Intervention to Prevent and Reduce Excessive Alcohol Use and Harm Among Young People Aged 14-15 Years: A “Think-Aloud” Study (Preprint)

Tinner, L. E., Kaner, E., Garnett, C., Mitchell, S., Hickman, M., Campbell, R. & MacArthur, G., 30 Apr 2020.

Research output: Working paper › Preprint

Bristol Medical School

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