• BS16 1LE

    United Kingdom

Organization profile

Organisation profile

The Dementia Research Group conducts preclinical and clinical research in dementia. We use molecular genetic, biochemical, cell culture-based and neuropathological approaches, as well as cognitive and neuroimaging studies in patients. Our aim is to translate our preclinical findings into applications that benefit patients with dementia. At the heart of this is our focus on the molecular epidemiology and pathogenesis of Alzheimer's disease and related dementias.

Our clinical research is based in the BRACE Centre and our preclinical research is based in the John James Laboratories at Frenchay Hospital. The John James Laboratories also house the Human Tissue Authority-licensed South West Dementia Brain Bank.

The Dementia Research Group is part of the University of Bristol's Institute of Clinical Neurosciences and is a member of the Bristol and Bath Alzheimer's Research UK Network Centre.

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    Research Output

    Abnormal scaffold attachment factor 1 expression and localisation in spinocerebellar ataxias and huntington’s chorea

    Buckner, N., Kemp, K. C., Scott, H. L., Shi, G., Rivers, C. A., Gialeli, A., Wong, L-F., Cordero Llana, O., Allen, N., Wilkins, A. & Uney, J. B., 2 Jun 2020, (Accepted/In press) In : Brain Pathology.

    Research output: Contribution to journalArticle (Academic Journal)

  • ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

    Evans, C., Miners, J. S., Piva, G., Willis, C. L., Heard, D. M., Kidd, E. J., Good, M. & Kehoe, P. G., 25 Jan 2020, In : Acta Neuropathologica. 18 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 50 Downloads (Pure)

    Alemtuzumab-related eosinophilic central nervous system vasculitis

    Leach, O. A., Hilton, D. A., Adams, W., Love, S. & Straukiene, A., 21 Feb 2020, In : Multiple Sclerosis Journal. 4 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 50 Downloads (Pure)

    Projects

    Student theses

    A Viral Approach to Translatome Profiling of CA1 Neurons During Associative Recognition Memory Formation

    Author: Gaunt, J., 25 Sep 2018

    Supervisor: Uney, J. (Supervisor), Warburton, C. (Supervisor) & Marucci, L. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Developing regulatable lentiviral vectors for the treatment of nerve injuries and Parkinson’s disease

    Author: Houghton, B., 14 May 2013

    Supervisor: Wong, L. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Dysregulation of microRNAs in dementia

    Author: Gerardo-Aviles, J., 28 Nov 2019

    Supervisor: Kehoe, P. G. (Supervisor) & Allen, S. J. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Prizes

    Alzheimer's Research UK Dementia Research Network Travel Bursary

    Tayler, Hannah M (Recipient), 11 Feb 2019

    Prize: Prizes, Medals, Awards and Grants

  • Asao Hirano Award

    Love, Seth (Recipient), 2012

    Prize: Prizes, Medals, Awards and Grants

    Activities

    British Neuropathology Society (BNS) conference

    Hannah M Tayler (Speaker)

    6 Mar 20198 Mar 2019

    Activity: Participating in or organising an event typesParticipation in conference

    L&R Postgraduate Seminar Series 2019

    Hannah M Tayler (Chair), , Ahmad Alghamdi (Speaker), , Jonathan Evans (Speaker), , Danya Bakhbakhi (Speaker), , Steven Bailey (Speaker), , Elliott Hibbs (Speaker), , Yulia Liem (Speaker), , Jamie Robinson (Speaker), , James Selwood (Speaker), , Flossie Carpenter (Speaker), , Steven Walker (Speaker), , Alfie Wearn (Speaker), , Esther Saunders-Jennings (Speaker), , Yunfei Li (Speaker), , Abdullah Alqasem (Speaker), , Reham Mashat (Speaker), , Richard Davis (Speaker), , Claire Williams (Speaker), , Anna Bibby (Speaker), , Carlos Muñoz-Neira (Speaker), , Georgina Kingshott (Speaker), , Amy Howell (Speaker), , Rob MacLachlan (Speaker), & Emily Hotton (Speaker)

    1 Jan 201931 Dec 2019

    Activity: Participating in or organising an event typesParticipation in conference

    File

    How to respond to reviewers' comments

    Hannah M Tayler (Participant)

    17 Jun 2019

    Activity: Participating in or organising an event typesParticipation in workshop, seminar, course