Dynamic Cell Biology

  • BS8 1TD

    United Kingdom

Organization profile

Organisation profile

Dynamic Cell Biology research focuses on the mechanisms and systems that allow cells in the body to perform their huge diversity of functions. Only by a detailed knowledge of how cells work, what they do, and how they interact with one another are we able to understand how body systems operate and how they fail. Such research has a crucial role to play in developing our understanding and treatment of human disease.

Advances in the field of human genomics have led to the identification of the genetic mutations and perturbed levels of gene expression that lie at the heart of complex diseases such as diabetes and cancer. But this knowledge in itself is insufficient to understand the disease process. Only by examining gene function in individual cells, tissues and whole organisms is it possible to fully understand the causes of disease and design new drug treatments.

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    Profiles

    Photo of Pete J Cullen

    Professor Pete J Cullen

    Person: Academic , Member, Group lead

    19962020

    Research Output

    Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting

    Evans, A. J., Daly, J., Anuar, A. N. K., Simonetti, B. & Cullen, P. J., 3 Aug 2020, In : Journal of Cell Science. 133, jcs246033.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 13 Downloads (Pure)

    A functional antagonism between RhoJ and Cdc42 regulates fibronectin remodelling during angiogenesis

    Sundararaman, A. & Mellor, H. H., 28 Aug 2020, In : Small GTPases. 6 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 16 Downloads (Pure)

    A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly

    Anton, Z., Betin, V. M. S., Simonetti, B., Traer, C. J., Attar, N., Cullen, P. J. & Lane, J. D., 15 Jul 2020, In : Journal of Cell Science. 133, 14, 38 p., jcs246306.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 41 Downloads (Pure)

    Projects

    Student theses

    Ageing and the Drosophila circadian clock

    Author: Curran, J., 23 Jan 2019

    Supervisor: Hodge, J. (Supervisor) & Tsaneva-Atanasova, K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    An Alternative Approach to Combat Antimicrobial Resistant Infections of Medical Implants and Devices

    Author: Jenkins, J. J., 28 Nov 2019

    Supervisor: Nobbs, A. (Supervisor), Su, B. (Supervisor) & Verkade, P. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    A systems biology approach using electrophysiology and modelling to determine the membrane clock

    Author: Smith, P., 23 Jan 2019

    Supervisor: Hodge, J. (Supervisor) & Tsaneva-Atanasova, K. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Activities

    BBSRC (External organisation)

    David Stephens (Chair)

    2016

    Activity: Membership typesMembership or peer review panel or committee

    BBSRC (External organisation)

    David Stephens (Chair)

    2015 → …

    Activity: Membership typesMembership or peer review panel or committee

    2015 C. elegans International Meeing

    Patricia E Kuwabara (Member of programme committee)

    24 Jun 201528 Jun 2015

    Activity: Participating in or organising an event typesParticipation in conference