Student theses
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A characterisation of mononuclear phagocyte dynamics in the healthy and regenerating zebrafish heart
Author: Moyse, B. R., 27 Sept 2022Supervisor: Richardson, B. (Supervisor) & Martin, P. B. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Ageing and the Drosophila circadian clock
Author: Curran, J., 23 Jan 2019Supervisor: Hodge, J. (Supervisor) & Tsaneva-Atanasova, K. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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An Alternative Approach to Combat Antimicrobial Resistant Infections of Medical Implants and Devices
Author: Jenkins, J. J., 28 Nov 2019Supervisor: Nobbs, A. (Supervisor), Su, B. (Supervisor) & Verkade, P. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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A systems biology approach using electrophysiology and modelling to determine the membrane clock
Author: Smith, P., 23 Jan 2019Supervisor: Hodge, J. (Supervisor) & Tsaneva-Atanasova, K. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Blood pressure control during exercise in people with hypertension
Author: Chant, B., 23 Jan 2019Supervisor: Paton, J. (Supervisor) & Hart, E. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Causal implications of common infections and platelet function on cardiovascular disease
Author: Chong, A., 21 Mar 2023Supervisor: Paternoster, L. (Supervisor), Richmond, R. (Supervisor), Davey Smith, G. (Supervisor) & Poole, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Characterisation of Alzheimer’s disease risk genes and their behavioural phenotypes in Drosophila melanogaster
Author: Preston, A. B., 20 Jun 2023Supervisor: Hodge, J. (Supervisor) & Dasgupta, S. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Characterisation of Ataxia Telangiectasia Mutated in RPE-1 cells and its role in cellular sensitivity to hypo-osmotic stress
Author: Panagi, M. D., 26 Nov 2020Supervisor: Mellor, H. H. (Supervisor) & Wood, W. J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Characterisation of Channelrhodopsin-2 in a neuronal culture model
Author: Chater, T. E., 15 May 2012Supervisor: Henley, J. M. (Supervisor) & Randall, A. D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Construction of the orb web in constant and changing abiotic conditions
Author: Phangurha, J., 23 Jan 2019Supervisor: Mortimer, B. (Supervisor) & Robert, D. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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CRISPR-Cas9 gene editing in an immortalized erythroid cell line for production of engineered red blood cells
Author: Hawksworth, J., 1 Oct 2019Supervisor: Spear, A. (Supervisor), Toye, A. (Supervisor) & Frayne, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Defining the Molecular Mechanisms of Constitutive Activity and Inverse Agonism at the P2Y12 G-protein Coupled Receptor
Author: Bancroft, S. K., 3 Oct 2023Supervisor: Mundell, S. J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Defining the molecular pharmacology of ticagrelor
Author: Dimofte, T., 6 Dec 2022Supervisor: Mundell, S. (Supervisor) & Hers, I. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Diabetes mellitus causes adiposopathy in bone marrow: investigation of the underpinning cellular and molecular mechanisms
Author: Gu, Y., 16 Jan 2024Supervisor: Madeddu, P. (Supervisor) & Mellor, H. H. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Dissecting the molecular and functional interactions of retromer
Author: Jellett, A., 19 Mar 2019Supervisor: Cullen, P. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Effect of Metabotropic Glutamate Receptor 5 Modulation on Blood Pressure and the Adaptive Immune System in Hypertension
Author: Cruise, T., 23 Jan 2019Supervisor: Paton, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Effects of cigarettes and e-cigarettes on platelet function: development of novel methods to assess the effect of chronic exposure.
Author: Vautrinot, J. J., 19 Mar 2024Supervisor: Poole, A. W. (Supervisor) & Hers, I. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Evaluating the use of neuronal cell culture models for investigating the molecular mechanisms underpinning Alzheimer’s Disease
Author: Collingridge, J., 7 May 2019Supervisor: Henley, J. M. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Exploiting Species Differences to Understand the Function and Pharmacology of the Cystic Fibrosis Transmembrane Conductance Regulator
Author: Bose, S., 23 Jan 2019Supervisor: Sheppard, D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Exploring the in vitro behaviour of endothelial cells in different cell culture models
Author: Harvey, L., 25 Jun 2019Supervisor: Mellor, H. (Supervisor) & Gaston, K. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Exploring the microclot-driven pre-metastatic niche: live imaging studies in zebrafish larvae
Author: Ward, J. R. R., 9 May 2023Supervisor: Martin, P. B. (Supervisor) & Nobes, C. D. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Exploring the role of BCL-3 in colorectal cancer cell therapeutic resistance
Author: Parker, C. T., 24 Jun 2021Supervisor: Martin, P. (Supervisor), Cullen, P. (Supervisor) & Williams, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Expression, Distribution, and Trafficking of Pore-Forming and Auxiliary Subunits of Kainate Receptors
Author: Al Momany, E., 28 Nov 2019Supervisor: Molnar, E. (Supervisor) & Henley, J. M. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Ex vivo culture of neutrophils to examine neutrophil biology and disorders
Author: Roberts, K., 21 Jun 2022Supervisor: Toye, A. M. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Genetic and molecular analysis of lawd-1, an essential gene in epithelial development and morphogenesis
Author: Qiao, M., 8 May 2018Supervisor: Kuwabara, P. E. (Supervisor) & Collinson, I. R. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Glial autophagy capability and the control of neuroinflammatory signaling in Parkinson’s disease.
Author: Trainer, T., 24 Jan 2023Supervisor: Lane, J. D. (Supervisor) & Carroll, B. M. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Identification of an Epithelial Cell Line for Two- and Three- Dimensional Studies of Intestinal Ion Transport
Author: Hawley, B. R., 21 Jun 2022Supervisor: Sheppard, D. N. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Identification of CLP-1 atypical calpain substrates in Caenorhabditis elegans
Author: Newman, L., 23 Jan 2019Supervisor: Kuwabara, P. (Supervisor) & Savery, N. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Identification of Protein Disulphide-Isomerase A3 Dependent Proteins from the Secretome of MDA-MB-231 Breast Cancer Cells
Author: Germon, A. L., 28 Nov 2019Supervisor: Adams, J. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Investigating Argonaute phosphorylation and miR-134 in Alzheimer's disease
Author: Walters, J. L., 21 Mar 2023Supervisor: Hanley, J. G. (Supervisor) & Ashby, M. C. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating DDX6 and its potential role in miRNA-mediated gene silencing events in neurones.
Author: Pring, K., 18 Jun 2024Supervisor: Hanley, J. G. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Investigating macrophage behaviour and interactions within erythroblastic islands
Author: Oates, T. C. L., 21 Mar 2023Supervisor: Toye, A. M. (Supervisor) & Frayne, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating mitochondrial fission factor (Mff) SUMOylation and effects on ubiquitination
Author: Chen, Z., 12 May 2022Supervisor: Henley, J. M. (Supervisor) & Hanley, J. G. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Investigating the effects of aspirin on colorectal cancer cell metabolism
Author: Holt, A. K., 22 Mar 2022Supervisor: Williams, A. (Supervisor) & Vincent, E. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating the extranuclear roles of the SUMO protease SENP3 in neurons
Author: Talandyte, K., 24 Mar 2020Supervisor: Hanley, J. (Supervisor) & Henley, J. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Investigating the formation of erythroblastic islands
Author: Hampton-O'Neil, L., 23 Jan 2019Supervisor: Toye, A. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating the mechanistic role of BCL-3 in promoting stem cell plasticity in colorectal cancer
Author: Timms, P., 25 Jan 2022Supervisor: Williams, A. (Supervisor) & Vincent, E. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating the process of reticulocyte maturation to erythrocytes in vitro
Author: Moura, P. L., 23 Jan 2020Supervisor: Toye, A. (Supervisor) & Frayne, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating the role of autophagy in musculoskeletal development and homeostasis using zebrafish
Author: Moss, J. J., 21 Jun 2022Supervisor: Lane, J. D. (Supervisor) & Hammond, C. L. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating the role of SUMOylation of Mitochondrial Fission Factor in Mitochondrial Dynamics
Author: Seager, R. A., 23 Jan 2020Supervisor: Henley, J. M. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigating the use of genetic engineering tools to enhance the functionality of an immortalised erythroid cell line
Author: Langlands, H. D., 21 Mar 2023Supervisor: Toye, A. M. (Supervisor) & Frayne, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigation and Characterisation of Extracellular Vesicles Generated by HbE/β-Thalassaemic Patients
Author: Kittivorapart, J., 28 Nov 2019Supervisor: Toye, A. (Supervisor) & Karamatic Crew, V. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Investigation into the Effect of Protein Disulphide Isomerase A3 on the Prom-Metastatic Phenotype of Breast Cancer Cells
Author: Young, H., 23 Jan 2019Supervisor: Lane, J. (Supervisor) & Adams, J. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Investigation into the expression of cardiomyocyte specific genes in cardiac macrophages after injury.
Author: Czapnik, P. J., 25 Jan 2022Supervisor: Richardson, B. J. (Supervisor) & Martin, P. B. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Kainate Receptors in various forms of plasticity
Author: Gurung, S., 23 Jan 2019Supervisor: Henley, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Mitochondrial import failure and rescue: links to neurodegeneration
Author: Needs, H. I. I., 21 Jun 2022Supervisor: Collinson, I. (Supervisor) & Henley, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Polarized Secretion of Endothelial Cells in Early Atherosclerosis
Author: Gan, X., 5 Dec 2023Supervisor: Mellor, H. H. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Proteolysis Targeting Chimeras: proteasomal degradation of platelet BTK and TEC as a novel approach in thrombosis prevention
Author: Munkacsi, A., 6 Dec 2022Supervisor: Hers, I. (Supervisor) & Poole, A. W. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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Proteomics-Based Analysis of The Coordination of Membrane Trafficking Events by The ATG12-ATG5 Autophagy Complex
Author: Baines, K., 23 Jan 2019Supervisor: Lane, J. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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Reducing the expression of Lap or Zydeco in Drosophila causes phenotypes similar to Alzheimer’s disease
Author: Parsons, T. A., 25 Jan 2022Supervisor: Hodge, J. J. L. (Supervisor) & Dodson, P. (Supervisor)
Student thesis: Master's Thesis › Master of Science by Research (MScR)
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