Elizabeth Blackwell Institute for Health Research

  • BS8 1UH

    United Kingdom

Research Output

2020

5′ modifications to CRISPR Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage

Mullally, G. E. L., Van Aelst, K., Mubarak Naqvi, M., Diffin, F. M., Karvelis, T., Gasiunas, G., Siksnys, V. & Szczelkun, M. D., 4 Jun 2020, In : Nucleic Acids Research. 13 p., gkaa477.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Downloads (Pure)

70% of people surveyed said they’d download a coronavirus app. Only 44% did. Why the gap?

Dennis, S. J., Perfors, A., Little, D. R., White, J., Mitchell, L., Geard, N., Garrett, P. M. & Lewandowsky, S., May 2020

Research output: Non-textual formWeb publication/site

Open Access

A Bayesian predictive approach for dealing with pseudoreplication

Lazic, S. E., Mellor, J. R., Ashby, M. C. & Munafo, M. R., 11 Feb 2020, In : Scientific Reports. 10, 10 p., 2366 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
48 Downloads (Pure)

A Bioinspired Strategy for the Enantioselective Synthesis of Bicyclic Oxygen Heterocycles

Rodriguez Venegas, E. & Willis, C. L., 16 Mar 2020, In : Organic Letters. 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Abnormal scaffold attachment factor 1 expression and localisation in spinocerebellar ataxias and huntington’s chorea

Buckner, N., Kemp, K. C., Scott, H. L., Shi, G., Rivers, C. A., Gialeli, A., Wong, L-F., Cordero Llana, O., Allen, N., Wilkins, A. & Uney, J. B., 2 Jun 2020, (Accepted/In press) In : Brain Pathology.

Research output: Contribution to journalArticle (Academic Journal)

Acculturation coping leads to heightened sensitivity to socially hurtful events

Lu, M., Hamamura, T., Chan, M., Li, C. & Park, J. H., 25 Mar 2020, In : Basic and Applied Social Psychology. 42, 4, p. 295-304 10 p.

Research output: Contribution to journalArticle (Academic Journal)

ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

Evans, C., Miners, J. S., Piva, G., Willis, C. L., Heard, D. M., Kidd, E. J., Good, M. & Kehoe, P. G., 25 Jan 2020, In : Acta Neuropathologica. 18 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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49 Downloads (Pure)

A checklist for safe robot swarms

Hunt, E. R. & Hauert, S., 31 Jul 2020, In : Nature Machine Intelligence. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

A Core Curriculum in the Biological and Biomedical Sciences for Dentistry

Bennett, J., Beeley, J., Anderson, P., Belfield, L., Brand, H., Didilescu, A., Dymock, D., Guven, Y., Hector, M., Holbrook, P., Jayasinghe, J., O'Sullivan, J., Riggio, M., Roger, V., Scheven, B., Sloan, A., Vandamme, K. & Manzanares, MC., 19 Mar 2020, In : European Journal of Dental Education. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Acquisition of aspect in L2: The computation of event completion by Japanese learners of English

Kaku-Macdonald, K., Liceras, J. M. & Kazanina, N., 22 Jan 2020, In : Applied Psycholinguistics. 41, 1, p. 185-214 30 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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Activation by sub-stoichiometric inhibition

Merdanovic, M., Burston, S. G., Schmitz, A. L., Köcher, S., Knapp, S., Clausen, T., Kaiser, M., Huber, R. & Ehrmann, M., 21 Jan 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 3, p. 1414-1418 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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126 Downloads (Pure)

Activation of bone marrow adaptive immunity in type 2 diabetes: rescue by co-stimulation modulator Abatacept

Santopaolo, M., Sullivan, N., Thomas, A. C., Alvino, V. V., Nicholson, L. B., Gu, Y., Spinetti, G., Kallikourdis, M., Blom, A. W. & Madeddu, P. R., 3 Jul 2020, (Submitted) In : Diabetologia.

Research output: Contribution to journalArticle (Academic Journal)

Activation of C-Reactive Protein Proinflammatory Phenotype in the blood retinal barrier in vitro: Implications for Age-related Macular Degeneration

Romero-Vázquez, S., Adán, A., Figueras-Roca, M., Llorenç, V., Slevin, M., Vilahur, G., Badimon, L., Dick, A. D. & Molins, B., 16 Jul 2020, In : Aging. 12, 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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10 Downloads (Pure)

Adding Biological Constraints to Deep Neural Networks Reduces their Capacity to Learn Unstructured Data

Tsvetkov, C. I., Malhotra, G., Evans, B. D. & Bowers, J. S., 1 May 2020, (Accepted/In press) Proceedings of the 42nd Annual Conference of the Cognitive Science Society 2020. Toronto, Canada

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Open Access

A de novo peroxidase is also a promiscuous yet stereoselective carbene transferase

Stenner, R., Steventon, J. W., Seddon, A. & Anderson, J. L. R., 21 Jan 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 3, p. 1419-1428 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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4 Citations (Scopus)
72 Downloads (Pure)

ADHD and depression: investigating a causal explanation

Riglin, L., Leppert, B., Dardani, C., Thapar, A., Rice, F., O'Donovan, M. C., Davey Smith, G., Stergiakouli, E., Tilling, K. M. & Thapar, A., 6 Apr 2020, In : Psychological Medicine. p. 1 - 8 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial

Birtle, A., Johnson, M., Donovan, J. L. & al., E., 5 Mar 2020, In : The Lancet. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

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Open Access

Adverse childhood experiences, DNA methylation age acceleration and cortisol in UK children: a prospective population-based cohort study

Tang, R., Howe, L. D., Suderman, M. J., Relton, C. L., Crawford, A. A. & Houtepen, L. C., 7 Apr 2020, In : Clinical Epigenetics. 12, 9 p., 55 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children

Marini, S., Davis, K. A., Soare, T. W., Zhu, Y., Suderman, M. J., Simpkin, A. J., Smith, A. D. A. C., Wolf, E. J., Relton, C. L. & Dunn, E. C., 1 Mar 2020, In : Psychoneuroendocrinology. 113, 104484.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data

Huynh-Le, M-P., Fan, C. C., Karunamuni, R., Walsh, E. I., Turner, E. L., Lane, J. A., Martin, R. M., Neal, D., Donovan, J. L., Hamdy, F. C., Parsons, J. K., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Olama, A. A. A., Benlloch, S., Muir, K. R., Gronberg, H., Wiklund, F., Aly, M. & 42 others, Schleutker, J., Sipeky, C., Tammela, T. L. J., Nordestgaard, B. G., Key, T. J., Travis, R. C., Pharoah, P., Pashayan, N., Khaw, K-T., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Maier, C., Vogel, W., Luedeke, M., Herkommer, K., Kibel, A. S., Cybulski, C., Wokolorczyk, D., Kluzniak, W., Cannon-Albright, L., Brenner, H., Schöttker, B., Holleczek, B., Park, J. Y., Sellers, T. A., Lin, H. Y., Slavov, C., Kaneva, R., Mitev, V., Batra, J., Clements, J., Spurdle, A., Teixeira, M. R., Paulo, P., Maia, S., Pandha, H., Michael, A., Mills, I. G., Andreassen, O. A., Dale, A. M. & Seibert, T. M., 24 Jun 2020, In : Cancer Epidemiology, Biomarkers and Prevention.

Research output: Contribution to journalArticle (Academic Journal)

A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly

Anton, Z., Betin, V. M. S., Simonetti, B., Traer, C. J., Attar, N., Cullen, P. J. & Lane, J. D., 15 Jul 2020, In : Journal of Cell Science. 133, 14, 38 p., jcs246306.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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AJP-Cell Physiology starts a Theme of Reviews on "Tissue Remodeling: From Regeneration to Fibrosis"

Stenina-Adognravi, O. & Adams, J., 18 May 2020, In : American Journal of Physiology - Cell Physiology. 318, 6, p. C1045-C1045

Research output: Contribution to journalEditorial (Academic Journal)

AJP-Cell Physiology starts a Theme of Reviews on "Tissue Remodelling: From Regeneration to Fibrosis"

Stenina-Adognravi, O. & Adams, J. C., 1 Jun 2020, In : AJP - Cell Physiology. 318, 6, p. C1045-C1045 4 p.

Research output: Contribution to journalEditorial (Academic Journal)

Alcohol consumption and internalising disorders in young adults of ALSPAC: a population-based study

Fernandes, G. S., Hammerton, G. L., Abeysekera, K. W. M., Mahedy, L. L., A, E., Lewis, G., Hickman, M. & Heron, J. E., 6 Jul 2020, In : Journal of Epidemiology and Community Health. 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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10 Downloads (Pure)

Alcohol use and cognitive functioning in young adults: improving causal inference

Mahedy, L., Suddell, S., Skirrow, C., Fernandes, G. S., Field, M., Heron, J., Hickman, M., Wootton, R. & Munafò, M. R., 13 Apr 2020, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle (Academic Journal)

Alemtuzumab-related eosinophilic central nervous system vasculitis

Leach, O. A., Hilton, D. A., Adams, W., Love, S. & Straukiene, A., 21 Feb 2020, In : Multiple Sclerosis Journal. 4 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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50 Downloads (Pure)

Alendronate use and bone mineral density gains in women with moderatesevere (Stages 3B - 5) chronic kidney disease: an open cohort multivariable and propensity score analysis from Funen, Denmark

Sanni Ali, M., Ernst, M., Robinson, D. E., Caskey, F., Arden, N. K., Ben-Shlomo, Y., Nybo, M., Rubin, K. H., Judge, A., Cooper, C., Javaid, M. K., Hermann, A. P. & Prieto-Alhambra, D., 1 Jun 2020, In : Archives of Osteoporosis. 15, 12 p., 81 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Alginate films augmented with chlorhexidine hexametaphosphate particles provide sustained antimicrobial properties for application in wound care

Duckworth, P., Maddocks, S., Rahatekar, S. & Barbour, M. E., 11 Mar 2020, In : Journal of Materials Science: Materials in Medicine. 31, 9 p., 33 (2020) .

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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27 Downloads (Pure)

Allergy, asthma, and the risk of breast and prostate cancer: a Mendelian randomization study

Jiang, X., Dimou, N. L., Zhu, Z., Bonilla, C., Lewis, S. J., Lindström, S., Kraft, P., Tsilidis, K. K., Martin, R. M. & PRACTICAL, CRUK, BPC3, CAPS and PEGASUS consortia, 31 Jan 2020, In : Cancer Causes and Control. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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111 Downloads (Pure)

A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia

Jones, H. J., Martin, D., Lewis, S. J., Davey Smith, G., O'Donovan, M. C., Owen, M. J., Walters, J. T. R. & Zammit, S., 24 Jun 2020, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Downloads (Pure)
Open Access
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11 Downloads (Pure)

A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

Stathakos, P., Jiménez Moreno, N., Crompton, L. A., Nistor, P. A., Badger, J. L., Barbuti, P. A., Kerrigan, T. L., Randall, A. D., Caldwell, M. A. & Lane, J. D., 23 Jan 2020, (Accepted/In press) In : Autophagy.

Research output: Contribution to journalArticle (Academic Journal)

A More Granular View of Neutrophils in Malaria

Amulic, B., Moxon, C. A. & Cunnington, A. J., 1 Jun 2020, In : Trends in Parasitology. 36, 6, p. 501-503 3 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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10 Downloads (Pure)

Analgesia in pet rabbits: A survey study on how pain is assessed and ameliorated by veterinary surgeons

Benato, L., Murrell, J. C., Blackwell, E. J., Saunders, R. & Rooney, N., 17 Apr 2020, In : Veterinary Record. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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15 Downloads (Pure)

An ecological approach to understanding obesity in captive lemurs

Mellor, E. L., Cuthill, I. C., Mendl, M. T. & Mason, G., 4 Mar 2020, International Society for Applied Ethology (ISAE) .

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

A Neurologist's Guide to REM Sleep Behaviour Disorder

Roguski, A., Rayment, D., Whone, A., Jones, M. & Rolinski, M., 25 May 2020, (Accepted/In press) In : Frontiers in Neurology. 32 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
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42 Downloads (Pure)

Animal affect and decision-making

Mendl, M. & Paul, E. S., 1 May 2020, In : Neuroscience and Biobehavioral Reviews. 112, p. 144-163 20 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
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48 Downloads (Pure)
Open Access
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58 Downloads (Pure)

A 'no' with a trace of 'yes': a mouse-tracking study of negative sentence processing

Darley, E. J., Kent, C. & Kazanina, N., 1 May 2020, In : Cognition. 198, 104084.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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48 Downloads (Pure)

Antibacterial effects of nanopillar surfaces are mediated by cell impedance, penetration and induction of oxidative stress

Jenkins, J. J., Mantell, J. M., Neal, C. R., Gholinia, A., Verkade, P., Nobbs, A. H. & Su, B., 2 Apr 2020, In : Nature Communications. 14 p., 1626 (2020) .

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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31 Downloads (Pure)

An update on FIP

Barker, E. N. & Tasker, S., 30 Apr 2020, (Accepted/In press) In : In Practice.

Research output: Contribution to journalReview article (Academic Journal)

A Platelet Function Modulator of Thrombin Activation Is Causally Linked to Cardiovascular Disease and Affects PAR4 Receptor Signaling

Rodriguez, B. A. T., Bhan, A., Beswick, A., Elwood, P. C., Niiranen, T. J., Salomaa, V., Trégouët, D-A., Morange, P-E., Civelek, M., Ben-Shlomo, Y., Schlaeger, T., Chen, M-H. & Johnson, A. D., 9 Jul 2020, In : American Journal of Human Genetics.

Research output: Contribution to journalArticle (Academic Journal)

A population-based cohort study examining the incidence and impact of psychotic experiences from childhood to adulthood, and prediction of psychotic disorder.

Sullivan, S. A., Kounali, D-Z., Cannon, M., David, A. S., Fletcher, P., Holmans, P. A., Jones, H., Jones, P. B., Linden, D. E. J., Lewis, G. H., Owen, M. J., O'Donovan, M. C., Rammos, A., Thompson, A., Wolke, D. & Zammit, S., 7 Jan 2020, In : American Journal of Psychiatry. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

A potpourri of biostatistical research: Special Issue for ISCB ASC 2018

Carlin, J. B., Kasza, J., Moreno-Betancur, M., Simpson, J., Bartlett, J., Metcalfe, C. & Lee, K., 1 Mar 2020, In : Biometrical Journal. 62, 2, p. 267-269 2 p.

Research output: Contribution to journalEditorial (Academic Journal)