Elizabeth Blackwell Institute for Health Research

  • BS8 1UH

    United Kingdom

Research Output

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Article (Academic Journal)
2020

(2S,6S)- and (2R,6R)- hydroxynorketamine inhibit the induction of NMDA receptor-dependent LTP at hippocampal CA1 synapses in mice

Kang, H. H., Park, P., Han, M., Tidball, P. J., Bortolotto, Z. A., Lodge, D. & Kaang, B-K., 20 Aug 2020, (Accepted/In press) In : Brain and Neuroscience Advances.

Research output: Contribution to journalArticle (Academic Journal)

5′ modifications to CRISPR Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage

Mullally, G. E. L., Van Aelst, K., Mubarak Naqvi, M., Diffin, F. M., Karvelis, T., Gasiunas, G., Siksnys, V. & Szczelkun, M. D., 4 Jun 2020, In : Nucleic Acids Research. 13 p., gkaa477.

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A Bayesian predictive approach for dealing with pseudoreplication

Lazic, S. E., Mellor, J. R., Ashby, M. C. & Munafo, M. R., 11 Feb 2020, In : Scientific Reports. 10, 10 p., 2366 (2020).

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2 Citations (Scopus)
53 Downloads (Pure)

A Bioinspired Strategy for the Enantioselective Synthesis of Bicyclic Oxygen Heterocycles

Rodriguez Venegas, E. & Willis, C. L., 16 Mar 2020, In : Organic Letters. 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Abnormal scaffold attachment factor 1 expression and localisation in spinocerebellar ataxias and huntington’s chorea

Buckner, N., Kemp, K. C., Scott, H. L., Shi, G., Rivers, C. A., Gialeli, A., Wong, L-F., Cordero Llana, O., Allen, N., Wilkins, A. & Uney, J. B., 24 Jun 2020, In : Brain Pathology. 15 p.

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Abnormal stiffness behaviour in artificial cactus-inspired reinforcement materials

Zampetakis, I., Dobah, Y., Liu, D., Woods, B., Bezazi, A., Perriman, A. & Scarpa, F., 14 Sep 2020, (Accepted/In press) In : Bioinspiration and Biomimetics.

Research output: Contribution to journalArticle (Academic Journal)

Accelerated long-term forgetting in healthy older adults predicts cognitive decline over one year

Wearn, A. R., Saunders-Jennings, E., Nurdal, V., Hadley, E., Knight, M. J., Newson, M. A., Kauppinen, R. A. & Coulthard, E. J., 15 Sep 2020, (Accepted/In press) In : Alzheimer's Research and Therapy.

Research output: Contribution to journalArticle (Academic Journal)

Acculturation coping leads to heightened sensitivity to socially hurtful events

Lu, M., Hamamura, T., Chan, M., Li, C. & Park, J. H., 25 Mar 2020, In : Basic and Applied Social Psychology. 42, 4, p. 295-304 10 p.

Research output: Contribution to journalArticle (Academic Journal)

ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

Evans, C., Miners, J. S., Piva, G., Willis, C. L., Heard, D. M., Kidd, E. J., Good, M. & Kehoe, P. G., 25 Jan 2020, In : Acta Neuropathologica. 18 p.

Research output: Contribution to journalArticle (Academic Journal)

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A checklist for safe robot swarms

Hunt, E. R. & Hauert, S., 31 Jul 2020, In : Nature Machine Intelligence. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

A Community Letter Regarding Sharing Biomolecular Simulation Data for COVID-19

Amaro, R. E. & Mulholland, A. J., 22 Jun 2020, In : Journal of Chemical Information and Modeling. 60, 6, p. 2653-2656 4 p.

Research output: Contribution to journalArticle (Academic Journal)

A Core Curriculum in the Biological and Biomedical Sciences for Dentistry

Bennett, J., Beeley, J., Anderson, P., Belfield, L., Brand, H., Didilescu, A., Dymock, D., Guven, Y., Hector, M., Holbrook, P., Jayasinghe, J., O'Sullivan, J., Riggio, M., Roger, V., Scheven, B., Sloan, A., Vandamme, K. & Manzanares, MC., 19 Mar 2020, In : European Journal of Dental Education. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Acquisition of aspect in L2: The computation of event completion by Japanese learners of English

Kaku-Macdonald, K., Liceras, J. M. & Kazanina, N., 22 Jan 2020, In : Applied Psycholinguistics. 41, 1, p. 185-214 30 p.

Research output: Contribution to journalArticle (Academic Journal)

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A cross-disorder PRS-pheWAS of 5 major psychiatric disorders in UK Biobank

Leppert, B., Millard, L. A. C., Riglin, L., Davey Smith, G., Thapar, A., Tilling, K. M., Walton, E. & Stergiakouli, E., 11 May 2020, In : PLoS Genetics. 20 p.

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Activation by sub-stoichiometric inhibition

Merdanovic, M., Burston, S. G., Schmitz, A. L., Köcher, S., Knapp, S., Clausen, T., Kaiser, M., Huber, R. & Ehrmann, M., 21 Jan 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 3, p. 1414-1418 5 p.

Research output: Contribution to journalArticle (Academic Journal)

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Activation of bone marrow adaptive immunity in type 2 diabetes: rescue by co-stimulation modulator Abatacept

Santopaolo, M., Sullivan, N., Thomas, A. C., Alvino, V. V., Nicholson, L. B., Gu, Y., Spinetti, G., Kallikourdis, M., Blom, A. W. & Madeddu, P. R., 3 Jul 2020, (Submitted) In : Cardiovascular Diabetology.

Research output: Contribution to journalArticle (Academic Journal)

Activation of C-Reactive Protein Proinflammatory Phenotype in the blood retinal barrier in vitro: Implications for Age-related Macular Degeneration

Romero-Vázquez, S., Adán, A., Figueras-Roca, M., Llorenç, V., Slevin, M., Vilahur, G., Badimon, L., Dick, A. D. & Molins, B., 16 Jul 2020, In : Aging. 12, 14, p. 13905—13923 19 p.

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Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

Hamdy, F. C., Donovan, J. L., Lane, J. A., Mason, M., Metcalfe, C., Holding, P., Wade, J., Noble, S., Garfield, K., Young, G., Davis, M., Peters, T. J., Turner, E. L., Martin, R. M., Oxley, J., Robinson, M., Staffurth, J., Walsh, E., Blazeby, J., Bryant, R. & 16 others, Bollina, P., Catto, J., Doble, A., Doherty, A., Gillatt, D., Gnanapragasam, V., Hughes, O., Kockelbergh, R., Kynaston, H., Paul, A., Paez, E., Powell, P., Prescott, S., Rosario, D., Rowe, E. & Neal, D., 28 Jul 2020, (Accepted/In press) In : Health technology assessment (Winchester, England). 24, 37, p. 1-176 176 p.

Research output: Contribution to journalArticle (Academic Journal)

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Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting

Evans, A. J., Daly, J., Anuar, A. N. K., Simonetti, B. & Cullen, P. J., 3 Aug 2020, In : Journal of Cell Science. 133, jcs246033.

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A de novo peroxidase is also a promiscuous yet stereoselective carbene transferase

Stenner, R., Steventon, J. W., Seddon, A. & Anderson, J. L. R., 21 Jan 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 3, p. 1419-1428 10 p.

Research output: Contribution to journalArticle (Academic Journal)

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6 Citations (Scopus)
81 Downloads (Pure)

ADHD and depression: investigating a causal explanation

Riglin, L., Leppert, B., Dardani, C., Thapar, A., Rice, F., O'Donovan, M. C., Davey Smith, G., Stergiakouli, E., Tilling, K. M. & Thapar, A., 6 Apr 2020, In : Psychological Medicine. p. 1 - 8 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Adjuvant chemotherapy in upper tract urothelial carcinoma (the POUT trial): a phase 3, open-label, randomised controlled trial

Birtle, A., Johnson, M., Donovan, J. L. & al., E., 5 Mar 2020, In : The Lancet. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

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Adverse childhood experiences, DNA methylation age acceleration and cortisol in UK children: a prospective population-based cohort study

Tang, R., Howe, L. D., Suderman, M. J., Relton, C. L., Crawford, A. A. & Houtepen, L. C., 7 Apr 2020, In : Clinical Epigenetics. 12, 9 p., 55 (2020).

Research output: Contribution to journalArticle (Academic Journal)

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Adversity exposure during sensitive periods predicts accelerated epigenetic aging in children

Marini, S., Davis, K. A., Soare, T. W., Zhu, Y., Suderman, M. J., Simpkin, A. J., Smith, A. D. A. C., Wolf, E. J., Relton, C. L. & Dunn, E. C., 1 Mar 2020, In : Psychoneuroendocrinology. 113, 104484.

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)

A functional antagonism between RhoJ and Cdc42 regulates fibronectin remodelling during angiogenesis

Sundararaman, A. & Mellor, H. H., 28 Aug 2020, In : Small GTPases. 6 p.

Research output: Contribution to journalArticle (Academic Journal)

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Age-dependent shift of AMPA receptors from synapses to intracellular compartments in Alzheimer´s disease: Immunocytochemical analysis of the CA1 hippocampal region in APP/PS1 transgenic mouse model

Martín-Belmonte, A., Aguado, C., Alfaro-Ruíz, R., Itakura, M., Moreno-Martínez, A. E., de la Ossa, L., Molnar, E., Fukazawa, Y. & Luján, R., 14 Sep 2020, (Accepted/In press) In : Frontiers in Aging Neuroscience.

Research output: Contribution to journalArticle (Academic Journal)

A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data

Huynh-Le, M-P., Fan, C. C., Karunamuni, R., Walsh, E. I., Turner, E. L., Lane, J. A., Martin, R. M., Neal, D., Donovan, J. L., Hamdy, F. C., Parsons, J. K., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Olama, A. A. A., Benlloch, S., Muir, K. R., Gronberg, H., Wiklund, F., Aly, M. & 42 others, Schleutker, J., Sipeky, C., Tammela, T. L. J., Nordestgaard, B. G., Key, T. J., Travis, R. C., Pharoah, P., Pashayan, N., Khaw, K-T., Thibodeau, S. N., McDonnell, S. K., Schaid, D. J., Maier, C., Vogel, W., Luedeke, M., Herkommer, K., Kibel, A. S., Cybulski, C., Wokolorczyk, D., Kluzniak, W., Cannon-Albright, L., Brenner, H., Schöttker, B., Holleczek, B., Park, J. Y., Sellers, T. A., Lin, H. Y., Slavov, C., Kaneva, R., Mitev, V., Batra, J., Clements, J., Spurdle, A., Teixeira, M. R., Paulo, P., Maia, S., Pandha, H., Michael, A., Mills, I. G., Andreassen, O. A., Dale, A. M. & Seibert, T. M., 24 Jun 2020, In : Cancer Epidemiology, Biomarkers and Prevention.

Research output: Contribution to journalArticle (Academic Journal)

A heterodimeric SNX4:SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly

Anton, Z., Betin, V. M. S., Simonetti, B., Traer, C. J., Attar, N., Cullen, P. J. & Lane, J. D., 15 Jul 2020, In : Journal of Cell Science. 133, 14, 38 p., jcs246306.

Research output: Contribution to journalArticle (Academic Journal)

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Alcohol use and cognitive functioning in young adults: improving causal inference

Mahedy, L., Suddell, S., Skirrow, C., Fernandes, G. S., Field, M., Heron, J., Hickman, M., Wootton, R. & Munafò, M. R., 25 Apr 2020, In : Addiction. 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Alemtuzumab-related eosinophilic central nervous system vasculitis

Leach, O. A., Hilton, D. A., Adams, W., Love, S. & Straukiene, A., 21 Feb 2020, In : Multiple Sclerosis Journal. 4 p.

Research output: Contribution to journalArticle (Academic Journal)

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Alendronate use and bone mineral density gains in women with moderate-severe (stages 3B-5) chronic kidney disease: an open cohort multivariable and propensity score analysis from Funen, Denmark

Ali, M. S., Ernst, M., Robinson, D. E., Caskey, F., Arden, N. K., Ben-Shlomo, Y., Nybo, M., Rubin, K. H., Judge, A., Cooper, C., Javaid, M. K., Hermann, A. P. & Prieto-Alhambra, D., 1 Jun 2020, In : Archives of Osteoporosis. 15, 1, 12 p., 81 (2020) .

Research output: Contribution to journalArticle (Academic Journal)

Alginate films augmented with chlorhexidine hexametaphosphate particles provide sustained antimicrobial properties for application in wound care

Duckworth, P., Maddocks, S., Rahatekar, S. & Barbour, M. E., 11 Mar 2020, In : Journal of Materials Science: Materials in Medicine. 31, 9 p., 33 (2020) .

Research output: Contribution to journalArticle (Academic Journal)

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Allergy, asthma, and the risk of breast and prostate cancer: a Mendelian randomization study

Jiang, X., Dimou, N. L., Zhu, Z., Bonilla, C., Lewis, S. J., Lindström, S., Kraft, P., Tsilidis, K. K., Martin, R. M. & PRACTICAL, CRUK, BPC3, CAPS and PEGASUS consortia, 31 Jan 2020, In : Cancer Causes and Control. 10 p.

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A Mendelian randomization study of the causal association between anxiety phenotypes and schizophrenia

Jones, H. J., Martin, D., Lewis, S. J., Davey Smith, G., O'Donovan, M. C., Owen, M. J., Walters, J. T. R. & Zammit, S., 24 Jun 2020, In : American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 10 p.

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Ammonium Transporters: A molecular dual carriageway

Allen, W. J. & Collinson, I. R., 25 Aug 2020, In : eLife. 9, 3 p., e61148.

Research output: Contribution to journalArticle (Academic Journal)

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A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

Stathakos, P., Jiménez Moreno, N., Crompton, L. A., Nistor, P. A., Badger, J. L., Barbuti, P. A., Kerrigan, T. L., Randall, A. D., Caldwell, M. A. & Lane, J. D., 14 Apr 2020, In : Autophagy. 17 p.

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A More Granular View of Neutrophils in Malaria

Amulic, B., Moxon, C. A. & Cunnington, A. J., 1 Jun 2020, In : Trends in Parasitology. 36, 6, p. 501-503 3 p.

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Analgesia in pet rabbits: A survey study on how pain is assessed and ameliorated by veterinary surgeons

Benato, L., Murrell, J. C., Blackwell, E. J., Saunders, R. & Rooney, N., 17 Apr 2020, In : Veterinary Record. 8 p.

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An Economic Evaluation of the Cost-Effectiveness of Opt-Out Hepatitis B and Hepatitis C Testing in an Emergency Department Setting in the United Kingdom

Williams, J., Vickerman, P., Douthwaite, S., Nebbia, G., Hunter, L., Wong, T., Ruf, M. & Miners, A., 14 Jul 2020, In : Value in Health. 23, 8, p. 1003-1011 9 p.

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An information theoretic approach to insulin sensing by human kidney podocytes

Pope, R. JP., Garner, K. L., Voliotis, M., Lay, A. C., Betin, V. MS., Tsaneva-Atanasova, K., Welsh, G. I., Coward, R. JM. & McArdle, C. A., 1 Aug 2020, In : Molecular and Cellular Endocrinology. 110976.

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