Find us here

Organization profile

Organisation profile

Head of Research Group : Professor Andres Lopez Bernal

My research concerns the adaptation of the human uterus to pregnancy and the prevention of prematurity. Preterm labour is the major cause of perinatal mortality and neurological disability in the surviving infants, but it is difficult to predict and manage. Current medication for preterm labour is inefficient or has serious maternal or fetal side effects.

I have focused on the study of the neurohypophyseal hormone oxytocin and inflammatory lipid mediators including prostaglandins in the control of uterine activity. Moreover, in order to predict preterm labour and identify women at risk, I am studying potential biomarkers among proteins, peptides and other molecules released from the feto-placental unit into the maternal circulation.

We have established novel functional methods in uterine smooth muscle (myometrium) combining contractility measurements with identification of specific phosphorylated residues in key contractile proteins. My research will lead to better understanding of the mechanism of parturition in women, and provide new approaches for pharmacological intervention in preterm labour and better methods for induction and augmentation of labour.

Fingerprint

Dive into the research topics where Endocrinology of Parturition Research Group is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Network

Recent external collaboration on country level. Dive into details by clicking on the dots.
  • Rogerio A. Lobo Award

    Andrés López Bernal (Recipient), 20 Mar 2018

    Prize: Prizes, Medals, Awards and Grants