Faculty of Health Sciences

2025

Accepting your Body after Cancer (ABC), a group-based online intervention for women treated for breast cancer: Study protocol for a feasibility randomised controlled trial

Lewis-Smith, H., Jones, A., White, P., Byford, S., Fairbrother, P., Potter, S. & Harcourt, D., 22 Jan 2025, In: BMJ Open. 15, 1, 9 p., e097817.

Research output: Contribution to journal › Protocol

Open Access

Amitriptyline for the prevention of post-herpetic neuralgia: study protocol for the ATHENA study

Wells, S. L., MacNeill, S. J., Liu, Y., Gilbertson, A., Everitt, H., Rees, S., Garfield, K. M., Fodor, I., Wylde, V., Johnson, R. W., Hay, A. D., Pickering, A. E., Kandiyali, R., Ridd, M. J. & Al, E., 14 Feb 2025, In: Skin Health and Disease. 5, 1, p. 1-8 8 p., vzaf002.

Research output: Contribution to journal › Protocol

Open Access

Developing a core outcome set for assessing interventions and care for parents after neonatal death in high-income countries (iCHOOSE Neonatal study): protocol for a mixed-methods study

Davies, A., Williams, C., Burden, C., Mullin, S., Moy, L., Redshaw, M., Patel, M., Fraser, A., Hinton, L., Lynch, M., Merriel, A., Siasakos, D., Webbe, J., Odd, D., Timlin, L., Watts, L. & Bakhbakhi, D., 3 Feb 2025, In: BMJ Open. 15, 2, e088251.

Research output: Contribution to journal › Protocol

Open Access

Estimating the burden of vaccine-preventable lower respiratory tract disease in UK primary care: protocol for a prospective surveillance study (AvonCAP GP2)

Duncan, P. R., Mears, R. E., Begier, E., Rouhbakhsh Halvaei, S., Southern, J., Porter, S. B., Hubler, R., Oben, G., Qian, G. Y., Lahuerta, M., Davis, T. D., Campling, J., Christensen, H., Oliver, J. L., Morales-Aza, M. B., Pan, K., Gray, S., Hyams, C., Danon, L. & Gessner, B. D. & 2 others, Finn, A. H. R. & Hay, A. D., 2 Jan 2025, In: BJGP Open. 8, 4, p. 1-10 10 p., BJGPO.2024.0129.

Research output: Contribution to journal › Protocol

Open Access

Exploring how PRIME-Parkinson care is implemented and whether, how and why it produces change, for who and under what conditions: a protocol for an embedded process evaluation within the PRIME-UK randomised controlled trial

Lloyd, K., Tenison, E., Smith, S. A. F., Lithander, F. E., Kidger, J. L., Brant, H. D., Redwood, S., Ben-Shlomo, Y. & Henderson, E. J., 2 Feb 2025, In: BMJ Open. 15, 1, p. e086353 9 p., e086353.

Research output: Contribution to journal › Protocol

Open Access

2024

AI-guided DVT diagnosis in primary care: protocol for cohort with qualitative assessment

Nothnagel, S. /., Hay, A. D. & Watson, J. C., Jul 2024, In: British Journal of General Practice Open.

Research output: Contribution to journal › Protocol

A pragmatic cluster randomised controlled trial of air filtration to prevent symptomatic winter respiratory infections (including COVID-19) in care homes (AFRI-c) in England: Trial protocol

Brierley, R. C. M., Taylor, J., Turner, N., Rees, S., Thorn, J., Metcalfe, C., Henderson, E. J., Clement, C., Welsh, T. J., Sargent, K., Morgan, G., Ready, D., Mellon, D., Wen, L., Kipping, R. & Hay, A. D., 23 Jul 2024, In: PLoS ONE. 19, 7, 18 p., e0304488.

Research output: Contribution to journal › Protocol

Open Access

1 Citation (Scopus)

A protocol for using human genetic data to identify circulating protein level changes that are the causal consequence of cancer processes.

Hobson, L. M., Martin, R. M., Smith Byrne, K., Davey Smith, G., Hemani, G., Gilbody, J. H., Yarmolinsky, J., Bailey, S., Goudswaard, L. J. & Haycock, P. C., 4 Jun 2024, (Submitted) In: PLoS ONE.

Research output: Contribution to journal › Protocol

Association between tumour somatic mutations and venous thromboembolism in the 100,000 Genomes Project cancer cohort: a study protocol

Cornish, N., Westbury, S. K., Warkentin, M. T., Thirlwell, C., Mumford, A. D. & Haycock, P. C., 24 Dec 2024, In: Wellcome Open Research. 9, 17 p., 640.

Research output: Contribution to journal › Protocol

Open Access

10 Downloads (Pure)

Development of a core data set for describing, measuring and reporting the learning curve in studies of novel invasive procedures: study protocol

Ramirez, J., Hoffmann, C., Corrigan, N., Kobetic, M. D., Macefield, R., Elliot, D., Blazeby, J., Potter, S., Stocken, D., Avery, K. & Blencowe, N. S., 25 Jul 2024, In: BMJ Open. 14, 7, 6 p., e084252.

Research output: Contribution to journal › Protocol

Open Access

Effectiveness and cost-effectiveness of guided self-help for depression for autistic adults: the Autism Depression Trial (ADEPT-2) - protocol for a multicentre, randomised controlled trial of a remotely delivered low-intensity intervention

Mckeon, H. E., Cotton, L., Aldridge, R., Cape, A., Clout, M., Cooper, K., Dagnan, D., Dawn, E., Frost, J., Georgakopoulou, A., Garfield, K., Horwood, J., Ingham, B., Jervis, V., Kessler, D., Langdon, P., Metcalfe, C., Rai, D., Realpe, A. & Russell, C. & 6 others, Sheridan, H., Slowinska, K., Thorn, J., Wen, L., Wiles, N. & Russell, A., 19 Nov 2024, In: BMJ Open. 14, 11, p. e084729 10 p., e084729.

Research output: Contribution to journal › Protocol

Open Access

File

1 Citation (Scopus)

13 Downloads (Pure)

Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK

UCL MS-STAT2 investigators, Blackstone, J., Williams, T., Nicholas, J. M., Bordea, E., Rice, C. M., Chataway, J. & al., E., 16 Sept 2024, In: BMJ Open. 14, 9, p. e086414 e086414.

Research output: Contribution to journal › Protocol

Open Access

3 Citations (Scopus)

Infection and telomere length: A systematic review protocol

Tunnicliffe, L., Muzambi, R., Bartlett, J., Howe, L. D., Basit, K. A. & Warren-Gash, C., 23 Apr 2024, In: BMJ Open. 14, 4, p. 1-5 5 p., e081881.

Research output: Contribution to journal › Protocol

Open Access

File

2 Citations (Scopus)

6 Downloads (Pure)

Investigating the association between genetically proxied circulating levels of immune checkpoint proteins and cancer survival: protocol for a Mendelian randomisation analysis

Bate, T. R., Martin, R. M., Yarmolinsky, J. & Haycock, P. C., 15 Feb 2024, In: BMJ Open. 14, 2, 10 p., e075981.

Research output: Contribution to journal › Protocol

Open Access

2 Citations (Scopus)

Protocol for the development of SPIRIT and CONSORT extensions for randomised controlled trials with surrogate primary endpoints: SPIRIT-SURROGATE and CONSORT-SURROGATE

Manyara, A. M., Davies, P., Stewart, D., Weir, C. J., Young, A., Butcher, N. J., Bujkiewicz, S., Chan, A.-W., Collins, G. S., Dawoud, D., Offringa, M., Ouwens, M., Ross, J. S., Taylor, R. S. & Ciani, O., 1 Feb 2024, In: BMJ Open. 12, 10, 8 p., e064304.

Research output: Contribution to journal › Protocol

Open Access

13 Citations (Scopus)

Protocol to decellularize porcine right ventricular outflow tracts using a 3D printed flow chamber

Harris, A. G., Schot, V., Carrabba, M., Iacobazzi, D., Ghorbel, M. T., Armstrong, J. P. K., Perriman, A. W., Caputo, M., Biglino, G. & Bartoli-Leonard, F., 15 Mar 2024, In: STAR Protocols. 5, 1, 37 p., 102899.

Research output: Contribution to journal › Protocol

Open Access

2 Citations (Scopus)

Rapid respiratory microbiological point-of-care-testing and antibiotic prescribing in primary care: Protocol for the RAPID-TEST randomised controlled trial

Abbs, S. E., Armstrong-Buisseret, L., Eastwood, K., Granier, S., Lane, A., Lui, M., Metcalfe, C., Mitchell, P., Muir, P., Ridd, M., Taylor, J., Yardley, L., Young, G. & Hay, A. D., 20 May 2024, In: PLoS ONE. 19, 5, 18 p., e0302302.

Research output: Contribution to journal › Protocol

Open Access

1 Citation (Scopus)

Scoping and targeted reviews to support development of SPIRIT and CONSORT extensions for randomised controlled trials with surrogate primary endpoints: protocol

Manyara, A. M., Davies, P., Stewart, D., Wells, V., Weir, C., Young, A., Taylor, R. & Ciani, O., 1 Feb 2024, In: BMJ Open. 12, 10, 6 p., e062798.

Research output: Contribution to journal › Protocol

Open Access

5 Citations (Scopus)

The BRIDGE project: A feasibility randomised controlled trial of brief, intensive assessment and integrated formulation for young people (age 14-24) with features of borderline personality disorder (Protocol)

Gajwani, R., Moran, P. A. & al., E., 24 Sept 2024, In: Frontiers in Psychiatry. 15, 10 p., 1389578.

Research output: Contribution to journal › Protocol

Open Access

The Cleft Collective: Protocol for a longitudinal prospective cohort study

Davies, A. J. V., Humphries, K. J., Lewis, S. J., Ho, K. M., Sandy, J. R. & Wren, Y. E., 5 Jul 2024, In: BMJ Open. 14, 7, p. 1-8 8 p., e084737.

Research output: Contribution to journal › Protocol

Open Access

5 Citations (Scopus)

2023

Cardiorespiratory Optimisation By Arteriovenous fistula Ligation after renal Transplantation (COBALT): study protocol for a multicentre randomised interventional feasibility trial

Surendrakumar, V., Aitken, E., Mark, P. B., Motallebzadeh, R., Hunter, J., Amer, A., Summers, D., Rennie, K., Rooshenas, L., Garbi, M., Sylvester, K., Hudson, C., Banks, J., Sidders, A., Norton, A., Slater, M., Bartlett, M., Knight, S. & Pettigrew, G., 9 Feb 2023, In: BMJ Open. 13, 2, e067668.

Research output: Contribution to journal › Protocol

Open Access

Improving access to general practice for people with severe and multiple disadvantage: a realist review protocol (the connection study)

Potter, L. C., McDonagh, L., Horwood, J., Farr, M. C., Feder, G. S. & Wong, G., 11 Oct 2023, In: Wellcome Open Research. 8, 10 p., 331.

Research output: Contribution to journal › Protocol

Open Access

Prehabilitation for frail patients undergoing total hip or knee replacement: protocol for the joint PREP feasibility randomised controlled trial

Khalid, T. Y., Ben-Shlomo, Y., Bertram, W. A., Culliford, L. A., England, C. Y., Henderson, E. J., Jameson, C. M., Jepson, M. J., Whitehouse, M. R. & Wylde, V., 7 Aug 2023, In: Pilot and Feasibility Studies. 9, 1, 138.

Research output: Contribution to journal › Protocol

Open Access

3 Citations (Scopus)

Protocol for a randomised controlled trial of a healthy relationship tool for men who use intimate partner violence (BETTER MAN)

Hegarty, K., Tarzia, L., Navarro Medel, C., Hameed, M., Chondros, P., Feder, G. S. & al, E., 2 Dec 2023, In: BMC Public Health. 23, 1, p. 1-13 13 p., 2395.

Research output: Contribution to journal › Protocol

Open Access

1 Citation (Scopus)

Standardizing Cranioplasty Outcomes Following Stroke or Traumatic Brain Injury: Protocol for the Development of a Core Outcome Set

Mee, H., Leon, A. C., Timofeev, I., Adeleye, A., Devi, I., Markland, N., Muehlschlegel, S., Bond, K., Clement, C., Grieve, K., Owen, N., Whiting, G., Turner, C., Rubiano, A., Shukla, D., Paul, M., Allanson, J., Pomeroy, V., Viaroli, E. & Warburton, E. & 7 others, Wells, A., Hawryluk, G., Helmy, A., Anwar, F., Honeybul, S., Hutchinson, P. & Kolias, A., 17 Apr 2023, In: JMIR Research Protocols. 12, e37442.

Research output: Contribution to journal › Protocol

Open Access

4 Citations (Scopus)

The NightLife study - the clinical and cost-effectiveness of thrice-weekly, extended, in-centre nocturnal haemodialysis versus daytime haemodialysis using a mixed methods approach: study protocol for a randomised controlled trial

Hull, K. L., Bramham, K., Brookes, C. L., Cluley, V., Conefrey, C., Cooper, N. J., Eborall, H., Fotheringham, J., Graham-Brown, M. P. M., Gray, L. J., Mark, P. B., Mitra, S., Murphy, G. J., Quann, N., Rooshenas, L., Warren, M. & Burton, J. O., 12 Aug 2023, In: Trials. 24, 1, 522.

Research output: Contribution to journal › Protocol

Open Access

1 Citation (Scopus)

2022

Assessment of nicotine replacement therapy for harm reduction in smokers: an n-of-1 study

Dyer, M., Stone, C. J., McDonald, S., McGree, J., Skinner, A. L., Tilling, K. M., Davey Smith, G., Attwood, A. S. & Munafo, M. R., 7 Oct 2022, In: Open Science Framework.

Research output: Contribution to journal › Protocol

Effect of SARS-CoV-2 infection in neonates or in pregnancy on developmental outcomes at 21-24 months (SINEPOST): study protocol for a prospective cohort study

Woodward, K. M., Cornish, R. P., Gale, C., Johnson, S., Knight, M., Kurinczuk, J. J. & Chakkarapani, E., 19 Sept 2022, In: BMJ Paediatrics Open. 6, 1, e001571.

Research output: Contribution to journal › Protocol

Open Access

File

3 Citations (Scopus)

37 Downloads (Pure)

Fluid restriction for treatment of symptomatic patent ductus arteriosus in preterm infants

MacLellan, A., Cameron, A. J., Cooper, C. & Mitra, S., 12 Dec 2022, In: Cochrane Database of Systematic Reviews. 2022, 12, CD015424.

Research output: Contribution to journal › Protocol

Open Access

1 Citation (Scopus)

Priorities for future research on reducing and stopping psychiatric medicines using a James Lind Alliance priority setting partnership: The PROTECT study protocol

Boland, M., Higgins, A., Beecher, C., Bracken, P., Burn, W., Cody, A., Framer, A., Gronlund, T. A., Horowitz, M., Huff, C., Jayacodi, S., Keating, D., Kessler, D., Konradsson Geuken, A., Lamberson, N., Montagu, L., Osborne, B., Smith, R. & Cadogan, C., 10 Nov 2022, In: HRB Open Research. 5, 72 p.

Research output: Contribution to journal › Protocol

Open Access

Study protocol: Evaluating the feasibility and acceptability of a smartwatch-based smoking relapse intervention

Stone, C. J., Essery, R., Matthews, J., Naughton, F., Munafo, M. R., Attwood, A. S. & Skinner, A. L., 21 Sept 2022, (E-pub ahead of print) In: Open Science Framework.

Research output: Contribution to journal › Protocol

Tackling Root Causes Upstream of Unhealthy Urban Development (TRUUD): Protocol of a five-year prevention research consortium

Black, D., Ayres, S., Bondy, K., Brierley, R., Campbell, R., Carhart, N., Coggon, J., Eaton, E., Fichera, E., Hatleskog, E., Hickman, M., Hicks, B., Pain, K., Pearce, N., Pilkington, P., Rosenberg, G. & Scally, G., 22 Jul 2022, In: Wellcome Open Research. 6, 35 p., 30.

Research output: Contribution to journal › Protocol

Open Access

11 Citations (Scopus)

67 Downloads (Pure)

Why Test study protocol: a UK-wide audit using the Primary Care Academic CollaboraTive (PACT) to explore the reasons for primary care testing

Burrell, A., Duncan, P., Bennett-Britton, I., Hodgson, S., Merriel, S. W. D., Waqar, S., Whiting, P. F., Watson, J. C. & Primary Care Academic CollaboraTive (PACT), 28 Sept 2022, In: British Journal of General Practice Open. 6, 3, 7 p., BJGPO.2022.0017.

Research output: Contribution to journal › Protocol

Open Access

File

3 Citations (Scopus)

40 Downloads (Pure)

2021

Clinical effectiveness and safety of baricitinib for the treatment of juvenile idiopathic arthritis-associated uveitis or chronic anterior antinuclear antibody-positive uveitis: study protocol for an open-label, adalimumab active-controlled phase 3 clinical trial (JUVE-BRIGHT)

Ramanan, A. V., Guly, C. M., Keller, S. Y., Schlichting, D. E., de Bono, S., Liao, R. & Quartier, P., 1 Dec 2021, In: Trials. 22, 1, 14 p., 689.

Research output: Contribution to journal › Protocol

Open Access

42 Citations (Scopus)

Community mobilisation approaches to preventing adolescent multiple risk behaviour: a realist review protocol

Tinner, L., Caldwell, D. & Campbell, R., 12 May 2021, In: Systematic Reviews. 10, 9 p., 147.

Research output: Contribution to journal › Protocol

Open Access

5 Citations (Scopus)

External validation of a clinical decision rule and neuroimaging rule-out strategy for exclusion of subarachnoid haemorrhage in the emergency department: A prospective observational cohort study

Roberts, T., Hirst, R., Hulme, W. & Horner, D., 29 May 2021, In: medRxiv.

Research output: Contribution to journal › Protocol

2020

Evaluating the effectiveness of the smartphone app, Drink Less, compared with the NHS alcohol advice webpage, for the reduction of alcohol consumption among hazardous and harmful adult drinkers in the UK at six-month follow-up: protocol for a randomised controlled trial

Garnett, C., Oldham, M., Angus, C., Beard, E., Burton, R., Field, M., Greaves, F., Hickman, M., Kaner, E., Loebenberg, G., Michie, S., Munafò, M., Pizzo, E. & Brown, J., 2 Jul 2020, In: Addiction.

Research output: Contribution to journal › Protocol

2019