Health Sciences Faculty Office

  • BS2 8DZ

    United Kingdom

Research Output

2020

Active monitoring, radical prostatectomy and radical radiotherapy in PSA-detected clinically localised prostate cancer: the ProtecT three-arm RCT

Hamdy, F. C., Donovan, J. L., Lane, J. A., Mason, M., Metcalfe, C., Holding, P., Wade, J., Noble, S., Garfield, K., Young, G., Davis, M., Peters, T. J., Turner, E. L., Martin, R. M., Oxley, J., Robinson, M., Staffurth, J., Walsh, E., Blazeby, J., Bryant, R. & 16 others, Bollina, P., Catto, J., Doble, A., Doherty, A., Gillatt, D., Gnanapragasam, V., Hughes, O., Kockelbergh, R., Kynaston, H., Paul, A., Paez, E., Powell, P., Prescott, S., Rosario, D., Rowe, E. & Neal, D., 28 Jul 2020, (Accepted/In press) In : Health technology assessment (Winchester, England). 24, 37, p. 1-176 176 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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20 Downloads (Pure)

Evaluating improvement interventions using routine data to support a learning health system: research design, data access, analysis and reporting

Weir, C. J., Heazell, A., Whyte, S. & Norman, J. E., 25 Feb 2020, In : BMJ Quality and Safety. 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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87 Downloads (Pure)

International benchmarking in type 1 diabetes: Large difference in childhood HbA1c between eight high-income countries but similar rise during adolescence-A quality registry study

Anderzén, J., Hermann, J. M., Samuelsson, U., Charalampopoulos, D., Svensson, J., Skrivarhaug, T., Fröhlich-Reiterer, E., Maahs, D. M., Akesson, K., Kapellen, T., Fritsch, M., Birkebaek, N. H., Drivvoll, A. K., Miller, K., Stephenson, T., Hofer, S. E., Fredheim, S., Kummernes, S. J., Foster, N., Amin, R. & 7 others, Hilgard, D., Rami-Merhar, B., Dahl-Jørgensen, K., Clements, M., Hanas, R., Holl, R. W. & Warner, J. T., 1 Jun 2020, In : Pediatric Diabetes. 21, 4, p. 621-627 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Interventions to reduce preterm birth and stillbirth, and improve outcomes for babies born preterm in low- and middle-income countries: a systematic review

Murray, S., Waters, D., Murray, S., Magowan, B., Whyte, S., Crampin, M., Freyne, B., Norman, J. E. & Reynolds, R. M., 24 Jun 2020, (Accepted/In press) In : Journal of Global Health.

Research output: Contribution to journalArticle (Academic Journal)

Metformin in Pregnancy Study (MiPS): protocol for a systematic review with individual patient data meta-analysis

Mousa, A., Løvvik, T., Hilkka, I., Carlsen, S. M., Morin-Papunen, L., Tertti, K., Rönnemaa, T., Syngelaki, A., Nicolaides, K., Shehata, H., Burden, C., Norman, J. E., Rowan, J., Dodd, J. M., Hague, W., Vanky, E. & Teede, H. J., 21 May 2020, In : BMJ Open. 10 (2020), 5, p. e036981 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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10 Downloads (Pure)

Observational cost-effectiveness analysis using routine data: Admission and discharge care bundles for patients with chronic obstructive pulmonary disease

Dixon, P., Hollingworth, W., Benger, J., Calvert, J., Chalder, M., King, A., MacNeill, S., Morton, K., Sanderson, E. & Purdy, S., 10 Mar 2020, (Accepted/In press) In : PharmacoEconomics - Open.

Research output: Contribution to journalArticle (Academic Journal)

Postal recruitment for genetic studies of preterm birth: A feasibility study

Keag, O. E., Murphy, L., Bradley, A., Deakin, N., Whyte, S., Norman, J. E. & Stock, S. J., 12 Feb 2020, In : Wellcome Open Research. (2020) 5, 26, 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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22 Downloads (Pure)

Predictors of length of stay following shoulder arthroplasty in a high-volume UK centre

Dacombe, P. J., Harries, L., McCann, P., Crowther, M., Packham, I., Sarangi, P. & Whitehouse, M. R., 17 Apr 2020, In : Annals of the Royal College of Surgeons of England. p. 1-6 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Progesterone and Preterm Birth

Norman, J. E., 1 Jul 2020, In : International Journal of Gynecology and Obstetrics. 150, 1, p. 24-30 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Downloads (Pure)
Open Access
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62 Downloads (Pure)

The ProtecT trial: analysis of the patient cohort, baseline risk stratification and disease progression

Bryant, R. J., Oxley, J., Young, G. J., Lane, J. A., Metcalfe, C., Davis, M., Turner, E. L., Martin, R. M., Goepel, J. R., Varma, M., Griffiths, D. F., Grigor, K., Mayer, N., Warren, A. Y., Bhattarai, S., Dormer, J., Mason, M., Staffurth, J., Walsh, E., Rosario, D. J. & 16 others, F Catto, J. W., Neal, D. E., Donovan, J. L., Hamdy, F. C., Bollina, P., Doble, A., Doherty, A., Gillatt, D., Gnanapragasam, V., Hughes, O., Kockelbergh, R., Kynaston, H., Paul, A., Paez, E., Rowe, E. & the ProtecT Study Group, 12 Feb 2020, In : BJU International. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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58 Downloads (Pure)

Using videoconferencing to deliver anatomy teaching to medical students on clinical placements

Allsop, S., Hollifield, M., Huppler, L., Baumgardt, D., Ryan, D., Van Eker, M. R., Spear, M. & Fuller, C. J., 1 Jun 2020, In : Translational Research in Anatomy. 19, 8 p., 100059.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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3 Citations (Scopus)
83 Downloads (Pure)

“Let’s Talk about Physical Activity”: Understanding the Preferences of Under-Served Communities when Messaging Physical Activity Guidelines to the Public

Nobles, J., Thomas, C., Gross, Z. B., Hamilton, M., Trinder-Widdess, Z., Speed, C., Gibson, A., Davies, R., Farr, M., Jago, R., Foster, C. & Redwood, S., 17 Apr 2020, In : International Journal of Environmental Research and Public Health. 17, 8, 16 p., 2782.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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52 Downloads (Pure)
2019

A preliminary exploration of the links between attachment disorganisation and schizotypy dimensions in adulthood

Shearman, N., Millings, A., Carroll, D. & Rowe, A., 1 Jun 2019, In : Schizophrenia Research. 208, p. 493-495 3 p.

Research output: Contribution to journalLetter (Academic Journal)

Open Access
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1 Citation (Scopus)
83 Downloads (Pure)

A Randomized Trial of Progesterone in Women with Bleeding in Early Pregnancy

Coomarasamy, A., Devall, A. J., Cheed, V., Harb, H., Middleton, L. J., Gallos, I. D., Williams, H., Eapen, A. K., Roberts, T., Ogwulu, C. C., Goranitis, I., Daniels, J. P., Ahmed, A., Bender-Atik, R., Bhatia, K., Bottomley, C., Brewin, J., Choudhary, M., Crosfill, F., Deb, S. & 22 others, Duncan, W. C., Ewer, A., Hinshaw, K., Holland, T., Izzat, F., Johns, J., Kriedt, K., Lumsden, M-A., Manda, P., Norman, J. E., Nunes, N., Overton, C. E., Quenby, S., Rao, S., Ross, J., Shahid, A., Underwood, M., Vaithilingam, N., Watkins, L., Wykes, C., Horne, A. & Jurkovic, D., 9 May 2019, In : New England Journal of Medicine. 380, 19, p. 1815-1824 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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33 Citations (Scopus)
130 Downloads (Pure)

Bicuspid Aortic Valve Alters Aortic Protein Expression Profile in Neonatal Coarctation Patients

Skeffington, K. L., Bond, A. R., Abdul-Ghani, S., Iacobazzi, D., Kang, S-L., Heesom, K. J., Wilson, M. C., Ghorbel, M., Stoica, S., Martin, R., Suleiman, M. S. & Caputo, M., 16 Apr 2019, In : Journal of Clinical Medicine. 8, 4, 14 p., 517.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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120 Downloads (Pure)

Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study

BILCAP study group, 1 May 2019, In : The Lancet Oncology. 20, 5, p. 663-673 11 p.

Research output: Contribution to journalArticle (Academic Journal)

129 Citations (Scopus)

Cathelicidins and the Onset of Labour

Boeckel, S. R. V., Hrabalkova, L., Baker, T. L., MacPherson, H., Frew, L., Boyle, A. K., McHugh, B. J., Wilson, K., Norman, J. E., Dorin, J. R., Davidson, D. J. & Stock, S. J., 14 May 2019, In : Scientific Reports. 9, 1, 12 p., 7356.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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112 Downloads (Pure)

Clinical and Patient-reported Outcome Measures in Men Referred for Consideration of Surgery to Treat Lower Urinary Tract Symptoms: Baseline Results and Diagnostic Findings of the Urodynamics for Prostate Surgery Trial; Randomised Evaluation of Assessment Methods (UPSTREAM)

Lewis, A. L., Young, G. J., Abrams, P., Blair, P. S., Chapple, C., Glazener, C. M. A., Horwood, J., McGrath, J. S., Noble, S., Taylor, G. T., Ito, H., Belal, M., Davies, M. C., Dickinson, A. J., Foley, C. L., Foley, S., Fulford, S., Gammal, M. M., Garthwaite, M., Harris, M. R. E. & 23 others, Ilie, P. C., Jones, R., Sabbagh, S., Mason, R. G., McLarty, E., Mishra, V., Mom, J., Morley, R., Natale, S., Nitkunan, T., Page, T., Payne, D., Rashid, T. G., Saeb-Parsy, K., Sandhu, S. S., Simoes, A., Singh, G., Sullivan, M., Tempest, H. V., Viswanath, S., Walker, R. M. H., Lane, J. A. & Drake, M. J., 1 May 2019, In : European Urology Focus. 5, 3, p. 340-350 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Citations (Scopus)
66 Downloads (Pure)

Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data

International Inflammatory Bowel Disease Genetics Consortium (IIBDGC), 17 Jul 2019, In : Scientific Reports. 9, 1, 18 p., 10351.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
93 Downloads (Pure)

Computational and theoretical approaches for mechanistic understanding: general discussion

Bauer, M., Cadge, J., Davies, D., Durand, D. J., Eisenstein, O., Ess, D., Fey, N., Gallarati, S., George, M., Hamilton, A., Harvey, J., Hintermair, U., Hulme, A. N., Ishii, Y., Jensen, V. R., Lloyd-Jones, G., Love, J., Lynam, J., Macgregor, S., Marder, T. B. & 10 others, Meijer, E. J., Morgan, P., Morris, R. H., Mwansa, J., Odom, A., Perutz, R., Reiher, M., Schafer, L., Slattery, J. & Young, T., 2019, In : Faraday Discussions.

Research output: Contribution to journalComment/debate (Academic Journal)

Consequences of being overweight or obese during pregnancy on diabetes in the offspring: a record linkage study in Aberdeen, Scotland

Lahti-Pulkkinen, M., Bhattacharya, S., Wild, S. H., Lindsay, R. S., Räikkönen, K., Norman, J. E., Bhattacharya, S. & Reynolds, R. M., 1 Aug 2019, In : Diabetologia. 62, 8, p. 1412-1419 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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147 Downloads (Pure)

Corrigendum: Does progesterone prophylaxis to prevent preterm labour improve outcome? A randomised double-blind placebo-controlled trial (OPPTIMUM)

Norman, J. E., Marlow, N., Messow, C-M., Shennan, A., Bennett, P. R., Thornton, S., Robson, S. C., McConnachie, A., Petrou, S., Sebire, N. J., Lavender, T., Whyte, S. & Norrie, J., Feb 2019, In : Health Technology Assessment.

Research output: Contribution to journalComment/debate (Academic Journal)

Dalitz plot analysis of the D + → K K + K + decay

The LHCb Collaboration, 1 Apr 2019, In : Journal of High Energy Physics. 2019, 4, 63.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
1 Citation (Scopus)

Development of a core information set for colorectal cancer surgery: a consensus study

McNair, A. G. K., Whistance, R. N., Main, B., Forsythe, R., Macefield, R., Rees, J., Pullyblank, A., Avery, K., Brookes, S., Thomas, M. G., Sylvester, P. A., Russell, A., Oliver, A., Morton, D., Kennedy, R., Jayne, D., Huxtable, R., Hackett, R., Dutton, S., Coleman, M. G. & 3 others, Card, M., Brown, J. & Blazeby, J., 14 Nov 2019, In : BMJ Open. 9, 11, p. e028623

Research output: Contribution to journalArticle (Academic Journal)

Effects of macrophage depletion on characteristics of cervix remodeling and pregnancy in CD11b-dtr mice

Yellon, S. M., Greaves, E., Heuerman, A. C., Dobyns, A. E. & Norman, J. E., 1 May 2019, In : Biology of Reproduction. 100, 5, p. 1386-1394 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Establishing Safe Zones to Avoid Nerve Injury in the Approach to the Humerus in Pediatric Patients: A Magnetic Resonance Imaging Study

O'Shea, R., Panwar, J., Chu Kwan, W., Stimec, J., Camp, M. W. & Gargan, M., 4 Dec 2019, In : The Journal of bone and joint surgery. American volume. 101, 23, p. 2101-2110 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Geographical differences in preterm delivery rates in Sweden: A population-based cohort study

Murray, S. R., Juodakis, J., Bacelis, J., Sand, A., Norman, J. E., Sengpiel, V. & Jacobsson, B., Jan 2019, In : Acta Obstetricia et Gynecologica Scandinavica. 98, 1, p. 106-116 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Gestational age at delivery of twins and perinatal outcomes: a cohort study in Aberdeen, Scotland

Murray, S. R., Bhattacharya, S., Stock, S. J., Pell, J. P. & Norman, J. E., 22 Jul 2019, In : Wellcome Open Research. 4, p. 65

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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70 Downloads (Pure)

HPV infection and pre-term birth: a data-linkage study using Scottish Health Data

Aldhous, M. C., Bhatia, R., Pollock, R., Vragkos, D., Cuschieri, K., Cubie, H. A., Norman, J. E. & Stock, S. J., 8 Mar 2019, In : Wellcome Open Research. 4, 48, 24 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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134 Downloads (Pure)

Interaction of salicylic acid analogues with Pluronic® micelles: Investigations on micellar growth and morphological transition

Shah, V., Bharatiya, B., Patel, V., Mishra, M. K., Shukla, A. D. & Shah, D. O., 1 Mar 2019, In : Journal of Molecular Liquids. 277, p. 563-570 8 p.

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)

miR-15a/-16 Inhibit Angiogenesis by Targeting the Tie2 Coding Sequence: Therapeutic Potential of a miR-15a/16 Decoy System in Limb Ischemia

Besnier, M., Shantikumar, S., Anwar, M., Dixit, P., Chamorro-Jorganes, A., Sweaad, W., Sala-Newby, G., Madeddu, P., Thomas, A. C., Howard, L., Mushtaq, S., Petretto, E., Caporali, A. & Emanueli, C., 6 Sep 2019, In : Molecular Therapy - Nucleic Acids. 17, p. 49-62 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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8 Citations (Scopus)
143 Downloads (Pure)

Molecular insights into sodium dodecyl sulphate mediated control of size for silver nanoparticles

Shah, V., Bharatiya, B., Mishra, M. K., Ray, D. & Shah, D. O., 1 Jan 2019, In : Journal of Molecular Liquids. 273, p. 222-230 9 p.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

My Baby's Movements: a stepped wedge cluster randomised controlled trial to raise maternal awareness of fetal movements during pregnancy study protocol

IMPACT Clinical Trials Network for Mothers’ and Babies’ Health, 21 Nov 2019, In : BMC Pregnancy and Childbirth. 19, 1, 11 p., 430.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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61 Downloads (Pure)

Nitroglycerin for treatment of retained placenta: a randomized, placebo-controlled, multicentre double blind trial in the UK

GOT-IT investigator team, 30 Dec 2019, In : PLoS Medicine. 16, 12, 16 p., e1003001.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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32 Downloads (Pure)

Observed compliance with safe sleeping guidelines in licensed childcare services

Staton, S., Pattinson, C., Smith, S., Pease, A., Blair, P., Young, J., Irvine, S. & Thorpe, K., 20 Nov 2019, In : Archives of Disease in Childhood. 104, 12, p. 1193-1197 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
135 Downloads (Pure)

Pharmacological management of abnormal tone and movement in cerebral palsy

Lumsden, D. E., Crowe, B., Basu, A., Amin, S., Devlin, A., Dealwis, Y., Kumar, R., Lodh, R., Lundy, C. T., Mordekar, S. R., Smith, M. & Cadwgan, J., 1 Aug 2019, In : Archives of Disease in Childhood. 104, 8, p. 775-780 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
199 Downloads (Pure)

Predicting and Experimentally Validating Hot-spot Residues at Protein-Protein Interfaces

Ibarra, A. A., Bartlett, G. J., Hegedüs, Z., Dutt, S., Hobor, F., Horner, K. A., Hetherington, K., Spence, K., Nelson, A., Edwards, T. A., Woolfson, D. N., Sessions, R. B. & Wilson, A. J., 16 Sep 2019, In : ACS Chemical Biology.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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5 Citations (Scopus)
134 Downloads (Pure)

Recent Trends in Stratospheric Chlorine From Very Short-Lived Substances

Hossaini, R., Atlas, E., Dhomse, S. S., Chipperfield, M. P., Bernath, P. F., Fernando, A. M., Mühle, J., Leeson, A. A., Montzka, S. A., Feng, W., Harrison, J. J., Krummel, P., Vollmer, M. K., Reimann, S., O'Doherty, S., Young, D., Maione, M., Arduini, J. & Lunder, C. R., 18 Jan 2019, In : Journal of Geophysical Research: Atmospheres.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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9 Citations (Scopus)
229 Downloads (Pure)

Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models

Boyle, A. K., Rinaldi, S. F., Rossi, A. G., Saunders, P. T. K. & Norman, J. E., Feb 2019, In : FASEB Journal. 33, 2, p. 2743-2758 16 p.

Research output: Contribution to journalArticle (Academic Journal)

Risk compensation and STI incidence in PrEP programmes: Latest evidence and research gaps

Quaife, M., Macgregor, L. W., Ong, J., Gafos, M., Torres-Rueda, S., Grant, H. & Vickerman, P., 22 Nov 2019, In : Lancet HIV. 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Severity Assessment in CDKL5 Deficiency Disorder

Demarest, S., Pestana-Knight, E. M., Olson, H. E., Downs, J., Marsh, E. D., Kaufmann, W. E., Partridge, C. A., Leonard, H., Gwadry-Sridhar, F., Frame, K. E., Cross, J. H., Chin, R. F. M., Parikh, S., Panzer, A., Weisenberg, J., Utley, K., Jaksha, A., Amin, S., Khwaja, O., Devinsky, O. & 3 others, Neul, J. L., Percy, A. K. & Benke, T. A., 1 Aug 2019, In : Pediatric Neurology. 97, p. 38-42 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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2 Citations (Scopus)
90 Downloads (Pure)

The DESiGN trial (DEtection of Small for Gestational age Neonate), evaluating the effect of the Growth Assessment Protocol (GAP): Study protocol for a randomised controlled trial

DESiGN Collaborative Group, 4 Mar 2019, In : Trials. 20, 1, 154.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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1 Citation (Scopus)
156 Downloads (Pure)

The journey of metformin from glycaemic control to mTOR inhibition and the suppression of tumour growth

Amin, S., Lux, A. & O'Callaghan, F., Jan 2019, In : British Journal of Clinical Pharmacology. 85, 1, p. 37-46 10 p.

Research output: Contribution to journalReview article (Academic Journal)

14 Citations (Scopus)

The QuinteT Recruitment Intervention supported five randomized trials to recruit to target: a mixed-methods evaluation

Rooshenas, L., By-Band-Sleeve study group, CSAW study group, HAND-1 study group, OPTIMA prelim study group, the Romio feasibility study group, Scott, L. J., Blazeby, J. M., Rogers, C. A., Tilling, K. M., Husbands, S., Conefrey, C., Mills, N., Metcalfe, C., Carr, A. J., Beard, D., Davis, T., Paramasivan, S., Jepson, M., Avery, K. & 4 others, Elliott, D., Wilson, C. A., Donovan, J. L. & Macpherson, I. E., 1 Feb 2019, In : Journal of Clinical Epidemiology. 106, p. 108-120 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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12 Citations (Scopus)
289 Downloads (Pure)

The UK guidelines for management and surveillance of Tuberous Sclerosis Complex

Amin, S., Kingswood, J. C., Bolton, P. F., Elmslie, F., Gale, D. P., Harland, C., Johnson, S. R., Parker, A., Sampson, J. R., Smeaton, M., Wright, I. & O'Callaghan, F. J., 1 Mar 2019, In : QJM. 112, 3, p. 171-182 12 p.

Research output: Contribution to journalArticle (Academic Journal)

5 Citations (Scopus)

Uphill quenching to reduce residual stress in a heat treatable aluminium alloy

Robinson, J. S., Truman, C. E., O’Donovan, A. & Rebelo Kornmeier, J., 13 Oct 2019, In : Materials Science and Technology (United Kingdom). 35, 15, p. 1864 -1871 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
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43 Downloads (Pure)
2018
Open Access
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2 Citations (Scopus)
249 Downloads (Pure)

Activity behaviors in lean and morbidly obese pregnant women

Fazzi, C., Mohd-Shukri, N., Denison, F. C., Saunders, D. H., Norman, J. E. & Reynolds, R. M., Oct 2018, In : Scandinavian Journal of Medicine and Science in Sports. 28, 10, p. 2189-2195 7 p.

Research output: Contribution to journalArticle (Academic Journal)