Research output per year
Research output per year
Organisation profile
Organisation profile
My research group investigates how the organism responds and adapts to stressful events.
Major research interests
- The signalling, epigenetic and genomic mechanisms in the brain underlying stress-related learning and memory processes.
- The regulation of the hypothalamic-pituitary-adrenal (HPA) axis under baseline and stress conditions.
- The physiological and neurobiological mechanisms underlying the beneficial effects of voluntary exercise on stress coping, HPA axis regulation, and anxiety-related and cognitive behaviour.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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Dr Karen R Mifsud
- Bristol Medical School (THS) - Research Fellow
- Neuro-Epigenetics of Stress and Cognition Research Group
Person: Academic , Member
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Professor J M H M Reul
- Bristol Medical School (THS) - Professor of Neuroscience
- Neuro-Epigenetics of Stress and Cognition Research Group
- Bristol Neuroscience
Person: Academic , Member, Group lead
Research output
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Genomic regulation of Krüppel-like-factor family members by corticosteroid receptors in the rat brain
Kennedy, C. L. M., Price, E. M., Mifsud, K. R., Salatino, S., Sharma, E., Engledow, S., Broxholme, J., Goss, H. M. & Reul, J. M. H. M., 7 Mar 2023, In: Neurobiology of Stress. 23, 100532.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Distinct regulation of hippocampal neuroplasticity and ciliary genes by corticosteroid receptors
Mifsud, K. R., Kennedy, C. L. M., Salatino, S., Sharma, E., Price, E. M., Haque, S. N., Gialeli, A., Goss, H. M., Panchenko, P. E., Broxholme, J., Engledow, S., Lockstone, H., Cordero Llana, O. & Reul, J. M. H. M., 6 Aug 2021, In: Nature Communications. 12, 1, 4737.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile18 Citations (Scopus)112 Downloads (Pure) -
Responding to Stress: Genomic and Nongenomic Actions of Corticosteroid Receptors in the Brain
Haque, S., Mifsud, K. R., Price, E. & Reul, J. M. H. M., Jan 2021, Stress: Genetics, Epigenetics and Genomics. Amsterdam:Elsevier, p. 215-227Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
Projects
- 5 Finished
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Epigenetic control of gene transcriptional and behavioural responses to stress in the dentate gyrus
1/10/13 → 1/10/16
Project: Research
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A highly dynamic role of corticosteroid-binding globulin in the stress-induced glucocorticoid hormone response
Linthorst, A. C. E. & Reul, J. M. H. M.
1/06/11 → 1/11/14
Project: Research
Student theses
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An investigation into the genomic actions of glucocorticoid binding receptors in the rat brain following acute stress and circadian influences
Author: Kennedy, C. L., 23 Jan 2020Supervisor: Reul, J. M. H. M. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
File -
Studies on epigenetic mechanisms and corticosteroid receptor action in the rat hippocampus
Author: Price, E., 25 Jan 2022Supervisor: Reul, J. M. H. M. (Supervisor) & Cordero Llana, O. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
File