School of Biochemistry

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• 3D Printing Enzyme Mediated Interpenetrating-Network Biohybrid Materials with Shape Changing Properties

  Author: Klemperer, R. G., 25 Jan 2022

  Supervisor: Perriman, A. W. (Supervisor) & Anderson, J. L. R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• A Baculoviral ‘Swag Bag’ Protein and DNA Delivery Toolkit for CRISPR-based Editing of Human Genomes

  Author: Capin, J. M., 2 Dec 2021

  Supervisor: Berger, I. (Supervisor) & Dillingham, M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

• A biophysical investigation into the self-assembly of α-helix - polyproline II helix oligomers

  Author: Heal, T. J., 28 Nov 2019

  Supervisor: Race, P. R. (Supervisor) & Woolfson, D. N. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• A characterisation of mononuclear phagocyte dynamics in the healthy and regenerating zebrafish heart

  Author: Moyse, B. R., 27 Sep 2022

  Supervisor: Richardson, B. (Supervisor) & Martin, P. B. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• An Alternative Approach to Combat Antimicrobial Resistant Infections of Medical Implants and Devices

  Author: Jenkins, J. J., 28 Nov 2019

  Supervisor: Nobbs, A. (Supervisor), Su, B. (Supervisor) & Verkade, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• An investigation of the activation of µ opioid receptors by fentanyls using in silico and in vitro approaches

  Author: Ramos-Gonzalez, N., 24 Jan 2023

  Supervisor: Kelly, E. P. (Supervisor) & Sessions, R. B. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Antibiotics from the Abyss - Establishing the Bristol Sponge Microbiome Collection as an Antibiotic Discovery Pipeline

  Author: Stennett, H. L., 28 Sep 2021

  Supervisor: Willis, C. (Supervisor), Race, P. (Supervisor) & Essex-Lopresti, A. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• A Promiscuous and Catalytically Proficient De Novo Carbene Transferase

  Author: Stenner, R. A., 12 May 2020

  Supervisor: Anderson, R. (Supervisor) & Seddon, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Assembly and characterisation of Diels-Alderase polymer conjugates for industrial biocatalysis

  Author: Strauss, A. A. I., 1 Oct 2019

  Supervisor: Burston, S. (Supervisor) & Race, P. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Baculoviral Nanosystems for DNA Delivery and Energy Sensing

  Author: Crocker, H. L., 23 Jan 2020

  Supervisor: Berger, I. (Supervisor) & Collinson, I. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Biocrystals: Growth, Synthesis and Materials

  Author: Abu El Magd, N., 31 Mar 2020

  Supervisor: Patil, A. (Supervisor) & Anderson, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Changes in Dendritic and Synaptic Function During Early Postnatal Development of the Mouse Barrel Cortex

  Author: Franchini, D., 23 Jan 2020

  Supervisor: Ashby, M. C. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Characterisation of Ataxia Telangiectasia Mutated in RPE-1 cells and its role in cellular sensitivity to hypo-osmotic stress

  Author: Panagi, M. D., 26 Nov 2020

  Supervisor: Mellor, H. H. (Supervisor) & Wood, W. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

• Characterisation of Channelrhodopsin-2 in a neuronal culture model

  Author: Chater, T. E., 15 May 2012

  Supervisor: Henley, J. M. (Supervisor) & Randall, A. D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Characterisation of the atypical calpain family of C elegans

  Author: Joyce, P., 2008

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Characterisation of the HELLS and Irc5 subfamily of chromatin remodellers

  Author: Topping, C. E., 23 Mar 2021

  Supervisor: Dillingham, M. (Supervisor) & Chambers, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Characterisation of two short QT syndrome potassium channel mutations

  Author: Butler, A., 23 Jan 2019

  Supervisor: Hancox, J. (Supervisor) & Dempsey, C. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Characterising Red Cell-Derived Vesicles in Sickle Cell Disease and Investigating Potential to Induce Tolerance to Human Red Cell Antigens

  Author: Drizou, D., 26 Nov 2020

  Supervisor: Blair, A. (Supervisor) & Anstee, D. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Computational design, construction, and characterisation of artificial peroxidases

  Author: Jenkins, J., 19 Mar 2019

  Supervisor: Anderson, R. (Supervisor) & Mulholland, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Computational Design and Structural Characterization of de novo Heme Maquettes

  Author: Hutchins, G., 24 Jun 2021

  Supervisor: Anderson, J. L. R. (Supervisor) & Mulholland, A. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Computation Design of Bioenergetic Membrane Proteins

  Author: Hardy, B. J., 21 Mar 2023

  Supervisor: Curnow, P. (Supervisor) & Anderson, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Conformational Control of Modular Proteins

  Author: Neary, T. E., 24 Mar 2020

  Supervisor: Parmeggiani, F. (Supervisor) & Anderson, R. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• CRISPR-Cas9 gene editing in an immortalized erythroid cell line for production of engineered red blood cells

  Author: Hawksworth, J., 1 Oct 2019

  Supervisor: Spear, A. (Supervisor), Toye, A. (Supervisor) & Frayne, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Crystallographic studies of NAD'+- dependent L- and D- 2-hydroxyacid dehydrogenases.

  Author: Dhaliwal, B., 2001

  Supervisor: Brady, R. L. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• De novo designed phospho-switchable protein-protein interaction domains for synthetic biology applications

  Author: Thompson, H. F., 24 Jan 2023

  Supervisor: Woolfson, D. N. (Supervisor) & Savery, N. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• De novo designed protein-protein interaction domains for synthetic biology applications in cells

  Author: Edgell, C. L., 23 Jan 2019

  Supervisor: Woolfson, D. (Supervisor) & Savery, N. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Development and validation of synthetically engineered microbial consortia

  Author: Salzano, D., 24 Jan 2023

  Supervisor: Di Bernardo, M. (Supervisor), Savery, N. (Supervisor) & Marucci, L. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Development of Novel Probes for Correlative Light Electron Microscopy

  Author: Tanner, H. R. C., 29 Sep 2020

  Supervisor: Verkade, P. (Supervisor) & Gersen, H. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Directed evolution of artificial oxidoreductases.

  Author: Steventon, J., 23 Jun 2020

  Supervisor: Mulholland, A. (Supervisor) & Anderson, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Dissecting the molecular and functional interactions of retromer

  Author: Jellett, A., 19 Mar 2019

  Supervisor: Cullen, P. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Effects of organic cosolvents on a de novo designed heme peroxidase

  Author: Frank, B., 29 Sep 2020

  Supervisor: Fermin, D. (Supervisor) & Anderson, R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Engineering of polychromatic photosystems for expanded solar energy conversion

  Author: Liu, J., 25 Jun 2019

  Supervisor: Jones, M. (Supervisor) & Woolfson, D. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Enzyme structure-function studies towards novel spirotetronates and materials

  Author: Rooms, L. D., 6 Dec 2022

  Supervisor: Race, P. R. (Supervisor), Curnow, P. (Supervisor) & Stach, J. E. M. (External person) (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Evaluating the use of neuronal cell culture models for investigating the molecular mechanisms underpinning Alzheimer’s Disease

  Author: Collingridge, J., 7 May 2019

  Supervisor: Henley, J. M. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Exploring the in vitro behaviour of endothelial cells in different cell culture models

  Author: Harvey, L., 25 Jun 2019

  Supervisor: Mellor, H. (Supervisor) & Gaston, K. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Exploring the role of BCL-3 in colorectal cancer cell therapeutic resistance

  Author: Parker, C. T., 24 Jun 2021

  Supervisor: Martin, P. (Supervisor), Cullen, P. (Supervisor) & Williams, A. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Expression, Distribution, and Trafficking of Pore-Forming and Auxiliary Subunits of Kainate Receptors

  Author: Al Momany, E., 28 Nov 2019

  Supervisor: Molnar, E. (Supervisor) & Henley, J. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Ex vivo culture of neutrophils to examine neutrophil biology and disorders

  Author: Roberts, K., 21 Jun 2022

  Supervisor: Toye, A. M. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

• Factors affecting Salmonella invasion of epithelial cells

  Author: Perrett, C. A., 2007

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Fatty acid construction within the biosynthesis of the polyketide antibiotic mupirocin

  Author: Rowe, M. T., 22 Mar 2022

  Supervisor: Crump, M. P. (Supervisor), Willis, C. (External person) (Supervisor) & Race, P. R. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Glial autophagy capability and the control of neuroinflammatory signaling in Parkinson’s disease.

  Author: Trainer, T., 24 Jan 2023

  Supervisor: Lane, J. D. (Supervisor) & Carroll, B. M. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Identification of CLP-1 atypical calpain substrates in Caenorhabditis elegans

  Author: Newman, L., 23 Jan 2019

  Supervisor: Kuwabara, P. (Supervisor) & Savery, N. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Identification of Protein Disulphide-Isomerase A3 Dependent Proteins from the Secretome of MDA-MB-231 Breast Cancer Cells

  Author: Germon, A. L., 28 Nov 2019

  Supervisor: Adams, J. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Insights into antibiotic inactivation by β-lactamases from multiscale simulations

  Author: Hirvonen, V. H. A., 28 Sep 2021

  Supervisor: Van der Kamp, M. (Supervisor) & Spencer, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Intracellular logistics : sorting nexins in retrograde transport of endogenous and exogenous cargo

  Author: Bujny, M. V., 2007

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Investigating Fusobacterium pathogenesis using molecular and genomic methods to inform vaccine design

  Author: Brewer, M. L., 1 Oct 2019

  Supervisor: Hill, D. (Supervisor) & Brady, L. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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• Investigating Interactions Of The SecYEG Holotranslocon With Periplasmic Chaperones And Outer Membrane Proteins

  Author: Williams-Jones, D. P., 11 May 2021

  Supervisor: Collinson, I. (Supervisor) & Dillingham, M. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Investigating macrophage behaviour and interactions within erythroblastic islands

  Author: Oates, T. C. L., 21 Mar 2023

  Supervisor: Toye, A. M. (Supervisor) & Frayne, J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

• Investigating mitochondrial fission factor (Mff) SUMOylation and effects on ubiquitination

  Author: Chen, Z., 12 May 2022

  Supervisor: Henley, J. M. (Supervisor) & Hanley, J. G. (Supervisor)

  Student thesis: Master's Thesis › Master of Science (MSc)

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• Investigating novel players in inflammatory cell migration to sites of tissue damage in vivo

  Author: Campbell, J. S., 23 Jan 2020

  Supervisor: Wood, W. J. (Supervisor)

  Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)

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