School of Physiology, Pharmacology & Neuroscience

Projects

Projects per year 1900 2012 2014 2015 2016 2017 2018 2019 2022 2023 2024 2029

• 1 Not started
• 40 Active
• 227 Finished

Projects per year

Search results

• Finished

  Development and validation of translational approaches to facilitate neurobiological and therapeutic advances in anxiety research.

  Robinson, E. S. J. (Principal Investigator)

  1/01/10 → 1/07/11

  Project: Research

• The endothelial surface layer in diabetic microangiopathy

  Salmon, A. H. J. (Principal Investigator)

  31/12/09 → 31/12/14

  Project: Research

  • Vascular Endothelial Growth Factor 100%
  • Isoform 70%
  • Glycocalyx 65%
  • Albuminuria 40%
  • Vascular Endothelial Growth Factor A 32%

• THE ROLE OF PDZ SCAFFOLD CASK AND CAMKII SIGNALLING IN SYNAPIC PLASTICITY AND LEARNING

  Hodge, J. J. L. (Principal Investigator)

  1/06/09 → 1/06/12

  Project: Research

  • Potassium Channel KCNQ 100%
  • Behavior (Neuroscience) 78%
  • CASK 66%
  • Calcium Signaling 55%
  • Mushroom Body 51%

• LOCAL TRANSLATION OF MRNA IN PRIMARY AFFERENT FIBRES: A NOVEL MECHANISM FOR THE CONTROL OF PAIN AND ITCH

  Lumb, B. M. (Principal Investigator)

  26/05/09 → 26/08/12

  Project: Research

• DEVELOPMENT OF NOVEL RELEASABLE CAGED IRON COMPOUNDS

  Poole, A. W. (Principal Investigator)

  1/04/09 → 1/07/09

  Project: Research

• ACTIVE AND PASSIVE COPING STRATEGIES: THE PERIAQUEDUCTAL GREY TO CEREBELLAR LINK

  Lumb, B. M. (Principal Investigator)

  1/03/09 → 1/09/13

  Project: Research

  • Periaqueductal Gray 100%
  • Behavior (Neuroscience) 87%
  • Cerebellum 57%

• INTERACTIONS OF THE PARIETAL CORTEX DURING COGNITION AND SLEEP

  Jones, M. W. (Principal Investigator)

  1/01/09 → 1/01/13

  Project: Research

  • Behavior (Neuroscience) 100%
  • Prefrontal Cortex 73%
  • Place Cell 69%
  • Local Field Potential 63%
  • Fastigial Nucleus 46%

• SYNTHETIC ANION CARRIERS FOR BIOMEDICAL APPLICATIONS

  Sheppard, D. N. (Principal Investigator)

  31/10/08 → 31/10/11

  Project: Research

• NORADRENERGIC MECHANISMS IN ATTENTION AND RESPONSE IN

  Robinson, E. S. J. (Principal Investigator)

  1/08/08 → 1/05/12

  Project: Research

  • Atomoxetine 100%
  • Norepinephrine 80%
  • Noradrenalin 80%
  • Reboxetine 57%
  • Reuptake 53%

• THE ROLE OF METABOTROPIC GLUTAMATE AND GABA-B RECEPTORS IN OLIGODENDROCYTE DEVELOPMENT, SURVIVAL AND VULNERABILITY IN THE IMMATURE BRAIN

  Molnar, E. (Principal Investigator)

  16/06/08 → 16/06/11

  Project: Research

  • Single-Nucleotide Polymorphism 100%
  • Synapse 93%
  • Promoter Region 83%
  • Isoform 83%
  • Pyrosequencing 62%

• ELUCIDATION OF THE ROLE OF KAINATE RECEPTOR SUBTYPES IN HIPPOCAMPAL SYNAPTIC FUNCTION USING NOVEL PHARMACOLOGICAL TOOLS

  Jane, D. E. (Principal Investigator)

  1/03/08 → 1/03/11

  Project: Research

  • Kainate Receptor 100%
  • Kainic Acid Receptor 62%
  • Long-Term Potentiation 57%
  • N Methyl Dextro Aspartic Acid Receptor 41%
  • Synapse 34%

• MRC CENTRE FOR SYNAPTIC PLASTICITY

  Collingridge, G. L. (Principal Investigator)

  1/01/08 → 1/10/15

  Project: Research

  • Cingulate Cortex 100%
  • Anterior Cingulate 100%
  • Hyperpathia 100%
  • Anterior Cingulate Cortex 100%
  • Neuronal Activity 100%

• CENTRE GRANT - LINK ACCOUNT

  Balthasar, N. (Principal Investigator)

  1/01/08 → 1/01/13

  Project: Research

• A MECHANISM FOR OBJECT-PLACE LEARNING IN THE PREFRONTAL CORTEX?

  Bashir, Z. I. (Principal Investigator)

  1/01/08 → 1/03/11

  Project: Research

  • Prefrontal Cortex 100%
  • Long-Term Depression 100%
  • Receptor 73%
  • Place Memory 64%
  • Hippocampus 62%

• DISCOVERING NOVEL SUBTYPE-SELECTIVE GLUTAMATE RECEPTOR ANTAGONISTS FOR THE STUDY OF HIPPOCAMPUL SYNAPTIC PLASTICITY

  Jane, D. E. (Principal Investigator)

  1/01/08 → 1/01/13

  Project: Research

  • Receptor 100%
  • Dextro Aspartic Acid 61%
  • Long-Term Potentiation 54%
  • NMDA Receptor 35%
  • Long Term Potentiation 27%

• MECHANISMS OF NMDA RECEPTOR DEPENDANT LTP AND LTD IN THE HIPPOCAMPUS

  Collingridge, G. L. (Principal Investigator)

  1/01/08 → 1/04/13

  Project: Research

  • Synaptic Plasticity 100%
  • Long-Term Depression 91%
  • Receptor 86%
  • Long-Term Potentiation 72%
  • NMDA Receptor 70%

• DISTRIBUTION AND MOLECULAR ORGANISATION OF KAINATE RECEPTORS IN THE MAMMALIAN CENTRAL NERVOUS SYSTEM

  Molnar, E. (Principal Investigator)

  1/12/07 → 1/12/11

  Project: Research

  • Kainate Receptor 100%
  • Glutamate Receptor 95%
  • N Methyl Dextro Aspartic Acid Receptor 95%
  • Receptor 95%
  • Isoform 95%

• ROLE OF A- AND M-TYPE K+ AND IH CHANNELS/CURRENTS IN SPONTANEOUS PAIN

  Djouhri, L.

  19/10/07 → 19/10/10

  Project: Research

• AP - GENETIC ANALYSIS OF THROMBOSIS AND HAEMOSTASIS IN ZEBRAFISH

  Poole, A. W. (Principal Investigator)

  1/10/07 → 1/04/09

  Project: Research

• RCUK FELLOW

  Balthasar, N. (Principal Investigator)

  1/10/07 → 1/10/12

  Project: Research

• THE ROLE OF SYNCHRONIZED OSCILLATORY NEURAL ACTIVITY IN VOMERONASAL CHEMOSENSATION

  Brennan, P. A. (Principal Investigator)

  1/09/07 → 1/09/10

  Project: Research

  • Olfactory Bulb 100%
  • Tyrosine Hydroxylase 54%
  • Norepinephrine 54%
  • Disinhibition 54%
  • Local Field Potential 54%

• MECHANISM OF PKC-MEDIATED DESENSITIZATION OF THE MORPHINE-ACTIVATED MU-OPIOID RECEPTOR IN NEURONES

  Kelly, E. P. (Principal Investigator)

  1/04/07 → 1/04/10

  Project: Research

  • Opiate Receptor 100%
  • Receptor 69%
  • Opiate 50%
  • G Protein Coupled Receptor 42%
  • Retina S Antigen 37%

• REGULATION OF GLOMERULAR FUNCTION BY VEGF

  Bates, D. O. (Principal Investigator)

  1/03/07 → 1/03/10

  Project: Research

  • Vascular Endothelial Growth Factor 100%
  • Glycocalyx 56%
  • Podocyte 39%
  • Isoform 31%
  • Glomerular Filtration Barrier 31%

• THE ROLE OF EPH/EPHRIN INTERACTION IN THE DEVELOPMENT OF INNER EAR INNERVATION

  Nobes, C. D. (Principal Investigator)

  1/02/07 → 1/03/11

  Project: Research

• PERIRHINAL NEURONAL ACTIVITY AND RECOGNITION MEMORY MECHANISMS

  Brown, M. W. (Principal Investigator)

  1/01/07 → 1/07/10

  Project: Research

  • Perirhinal Cortex 100%
  • Recognition Memory 90%
  • Familiarity 58%
  • Engram 30%
  • Discrimination 20%

• ABNORMAL INTERACTIONS BETWEEN THE HIPPOCAMPUS AND PREFRONTAL CORTEX IN RODENT MODELS OF SCHIZOPHRENIA

  Jones, M. W. (Principal Investigator)

  1/09/06 → 1/03/11

  Project: Research

  • Hippocampus 100%
  • Local Field Potential 54%
  • NMDA Receptor 51%
  • Prefrontal Cortex 48%
  • Dentate Gyrus 48%

• NOCICEPTIVE INPUT TO CEREBELLAR PATHWAYS AND ITS BEHAVIOURAL SIGNIFICANCE

  Apps, R. (Principal Investigator)

  1/02/06 → 1/07/09

  Project: Research

• RCUK FELLOWSHIP

  Jones, M. W. (Principal Investigator)

  1/01/06 → 1/01/11

  Project: Research

• INTRACELLULAR SIGNALLING PATHWAYS ESSENTIAL TO RECOGNITION MEMORY

  Brown, M. W. (Principal Investigator)

  1/11/05 → 1/11/10

  Project: Research

  • Recognition Memory 100%
  • Perirhinal Cortex 65%
  • Hippocampus 46%
  • Prefrontal Cortex 33%
  • Immediate Early Gene 32%

• MHC PEPTIDE LIGANDS AND THE RECOGNITION OF CHEMOSENSORY INDIVIDUALITY IN MICE

  Brennan, P. A. (Principal Investigator)

  1/11/05 → 1/11/08

  Project: Research

  • Pheromone 100%
  • Hypothalamus 100%
  • Reproduction 100%
  • Support System 100%
  • Olfactory System 100%

• FUNCTIONAL ANALYSIS OF THE INTERACTION OF CYTOHESIN 2 GTP-EXCHANGE FACTOR WITH MAGUIN-1

  Venkateswarlu, K.

  1/10/05 → 1/10/08

  Project: Research

• MOLECULAR AND CELLULAR ANALYSIS OF THE INTERACTION BETWEEN CENTAURIN-A1 AND A NOVEL KINESIN MOTOR PROTEIN IN MEMBRANE TRAFFICKING

  Venkateswarlu, K. (Principal Investigator)

  1/09/05 → 1/09/08

  Project: Research

  • Nucleotide Binding Site 100%
  • Calcium-Sensing Receptor 100%
  • Arrestin 100%
  • ELMO (Protein) 100%
  • Adenosine Diphosphate 100%

• ACADEMIC FELLOWSHIP RCUK

  Robinson, E. S. J. (Principal Investigator)

  1/07/05 → 1/07/10

  Project: Research

• THE USE OF HUMAN-MURINE CFTR CHIMERAS TO INVESTIGATE THE COUPLING OF PERMEATION AND GATING IN THE CFTR CHLORIDE CHANNEL

  Sheppard, D. N. (Principal Investigator)

  1/05/05 → 1/05/08

  Project: Research

  • Cystic Fibrosis Transmembrane Conductance Regulator 100%
  • Chloride Channel 51%
  • Cystic Fibrosis 44%
  • Behavior (Neuroscience) 23%
  • Thyroid Hormone 21%

• VASCULAR EPITHELIAL GROWTH FACTOR RECEPTOR (VEGF-R) COMPLEXES AND VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) SIGNALLING IN PODOCYTES

  Foster, R. R.

  1/04/05 → 1/04/06

  Project: Research

• GENETIC STUDIES OF WOUND HEALING IN DROSPHILA

  Martin, P. B. (Principal Investigator)

  1/11/04 → 1/11/07

  Project: Research

  • Tissue Repair 100%
  • Macrophage 100%
  • Inflammatory Cell 62%
  • Inflammation Response 62%
  • Tissue Regeneration 50%

• ELUCIDATION OF THE ROLE OF KAINATE RECEPTORS IN HIPPOCAMPAL SYNAPTIC MECHANISMS USING NOVEL PHARMACOLOGICAL TOOLS

  Jane, D. E. (Principal Investigator)

  1/10/04 → 1/01/08

  Project: Research

  • Receptor 100%
  • Kainate Receptor 80%
  • Glutamic Acid 75%
  • Aspartic Acid 63%
  • Theta Rhythm 25%

• RESEARCH EQUIPMENT SUPPLEMENT SCHEME

  Nobes, C. D. (Principal Investigator)

  1/05/04 → 1/05/05

  Project: Research

• CELL AND MOLECULAR MECHANISMS UNDERLYING NERVE AXON GUIDANCE AND REGENERATION

  Nobes, C. D. (Principal Investigator)

  1/09/03 → 1/09/06

  Project: Research

  • Receptor Binding 100%
  • Angiogenesis 100%
  • Ephrin Receptor 100%
  • Ephrin 100%
  • Ephrin B2 100%

• FUNCTIONAL GENOMICS OF HOMEOSTATIC PLASTICITY ON PHENOTYPICALLY DEFINED HYPTHALMIC NEURONS

  Rogers, I. P.

  15/02/03 → 15/02/06

  Project: Research

• FLAGELLAR DYNEINS IN WILD-TYPE AND KNOCK-OUT MICE

  Woolley, D. M.

  1/01/03 → 1/07/06

  Project: Research

• GENE TRANSFER STUDIES USING ADENOVIRAL VECTORS

  Kasparov, S.

  1/12/01 → 1/06/02

  Project: Research

• ARE ALL TRKA AND IB4 + VE SENSORY NEURONES NOCICEPTIVE? STUDIES OF THEIR MEMBRANE PROPERTIES AND RELATIVE CONTRIBUTIONS TO CHRNOIC PAIN STATES

  Lawson, S. N. (Principal Investigator)

  1/08/01 → 1/08/04

  Project: Research

• PERIODONTAL DISEASE AND THE RELATIONSHIP BETWEEN INFLAMMATION AND PAIN

  Donaldson, L. F. (Principal Investigator)

  1/05/01 → 1/11/06

  Project: Research

  • Galanin 100%
  • Nociceptor 81%
  • Galanin Receptor 2 66%
  • Nerve Injury 46%
  • Allodynia 41%

• SYNTHESIS AND PHARMACOLOGICAL CHARACTERIZATION OF SUBTYPE SELECTIVE GROUP III METABOTROPIC GLUTAMATE RECEPTOR AGONISTS

  Jane, D. E. (Principal Investigator)

  12/03/01 → 12/03/03

  Project: Research

• CEREBELLAR CELL-SPECIFIC EXPRESSION OF MOLECULAR AND FUNCTIONAL VARIANTS OF P TYPE AND ALPHA 1A CALCIUM CHANNELS

  Usowicz, M. M. (Principal Investigator)

  1/03/01 → 1/11/04

  Project: Research

• ROLE OF THE LATERAL CEREBELLUM IN THE VISUAL GUIDANCE OF MOVEMENT

  Marple-Horvat, D. E.

  1/08/00 → 1/03/04

  Project: Research

• ION CHANNEL COUPLING IN CENTRAL NEURONS

  Marrion, N. V. (Principal Investigator)

  1/04/00 → 1/10/05

  Project: Research

• AGONIST - INDUCED REGULATION OF METABOTROPIC GLUTAMATE RECEPTORS

  Kelly, E. P.

  1/04/00 → 1/04/03

  Project: Research

• ARE KCNQ2 AND KCNQ3 THE MOLECULAR CORRELATES OF THE MAMMALIAN M-CHANNEL

  Marrion, N. V. (Principal Investigator)

  1/02/00 → 1/02/03

  Project: Research