School of Physiology, Pharmacology & Neuroscience

  • BS8 1TD

    United Kingdom

Research Output

2020

3D localization microscopy and 4D localization microscopy and tracking methods and systems

Cannell, M. B., Soeller, C. & Beddeley, D., 25 Feb 2020, US PATENT OFFICE, Patent No. US10571674B2, 28 Mar 2018, Priority date 24 Oct 2010, Priority No. NZ58819910

Research output: Patent

A Bayesian predictive approach for dealing with pseudoreplication

Lazic, S. E., Mellor, J. R., Ashby, M. C. & Munafo, M. R., 11 Feb 2020, In : Scientific Reports. 10, 10 p., 2366 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
48 Downloads (Pure)

Airway management for dental clearance in a preschool child: A UK survey

Shrimpton, A. J. & Gill, H., 16 Apr 2020, (Accepted/In press) In : Paediatric Anaesthesia.

Research output: Contribution to journalArticle (Academic Journal)

A Neurologist's Guide to REM Sleep Behaviour Disorder

Roguski, A., Rayment, D., Whone, A., Jones, M. & Rolinski, M., 25 May 2020, (Accepted/In press) In : Frontiers in Neurology. 32 p.

Research output: Contribution to journalReview article (Academic Journal)

A novel G protein-biased agonist at the δ opioid receptor with analgesic efficacy in models of chronic pain

Conibear, A. E., Asghar, J., Hill, R., Henderson, G., Borbely, E., Tekus, V., Helyes, Z., Palandri, J., Bailey, C., Starke, I., von Mentzer, B., Kendall, D. & Kelly, E., 20 Jan 2020, In : Journal of Pharmacology and Experimental Therapeutics. 372, 2, p. 224-236 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
76 Downloads (Pure)

An update on the structure of hERG

Butler, A., Helliwell, M. V., Zhang, Y., Hancox, J. C. & Dempsey, C. E., 24 Jan 2020, In : Frontiers in Pharmacology. 10, 13 p., 1572.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
34 Downloads (Pure)

A population of injury responsive lymphoid cells expresses mpeg1.1 in the adult zebrafish heart

Moyse, B. R. & Richardson, R., 20 Jul 2020, (Accepted/In press) In : ImmunoHorizons.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
90 Downloads (Pure)

Astrocytes monitor cerebral perfusion and control systemic circulation to maintain brain blood flow

Marina, N., Christie, I. N., Korsak, A., Doronin, M., Brazhe, A., Hosford, P. S., Wells, J. A., Sheikhbahaei, S., Humoud, I., Paton, J. F. R., Lythgoe, M. F., Semyanov, A., Kasparov, S. & Gourine, A. V., 9 Jan 2020, In : Nature Communications. 11, 1, 9 p., 131 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
65 Downloads (Pure)

Blood platelets stimulate cancer extravasation through TGFβ-mediated downregulation of PRH/HHEX

Marcolino, E., Siddiqui, Y. H., van den Bosch, M., Poole, A. W., Jayaraman, P. S. & Gaston, K., 4 Feb 2020, In : Oncogenesis. 9, 12 p., 10 (2020).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
36 Downloads (Pure)

Cannabidiol improves survival and behavioural co-morbidities of Dravet syndrome in mice

Patra, P. H., Serafeimidou-Pouliou, E., Bazelot, M., Whalley, B. J., Williams, C. M. & McNeish, A. J., 19 May 2020, In : British Journal of Pharmacology. 177, 12, p. 2779-2792 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Downloads (Pure)

Carbonic Anhydrase Inhibitors Suppress Platelet Procoagulant Responses and In Vivo Thrombosis

Agbani, E. O., Zhao, X., Williams, C. M., Aungraheeta, R., Hers, I., Swenson, E. R. & Poole, A. W., 1 Jan 2020, In : Platelets. 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Cardiac effects of repeated focal seizures in rats induced by intrahippocampal tetanus toxin: bradyarrhythmias, tachycardias and prolonged interictal QT interval

Jefferys, J. G. R., Ashby-Lumsden, A. & Lovick, T. A., 22 Mar 2020, In : Epilepsia.

Research output: Contribution to journalArticle (Academic Journal)

CFTR: New insights into structure and function and implications for modulation by small molecules

Kleizen, B., Hunt, J., Callebaut, I., Hwang, T-C., Sermet-Gaudelus, I., Hafkemeyer, S. & Sheppard, D. N., Mar 2020, In : Journal of Cystic Fibrosis. 19, Supplement 1, p. S19-S24 6 p.

Research output: Contribution to journalArticle (Academic Journal)

4 Citations (Scopus)

Changing trends in the use of novel oral anticoagulants and warfarin for treating non-valvular atrial fibrillation

Birkinshaw, A., Fry, C. H., Fluck, D., Sharma, P. & Han, T. S., 29 Mar 2020, In : JRSM Cardiovascular Disease. 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
27 Downloads (Pure)
Open Access
File
52 Downloads (Pure)

Complementarity between Arrhythmia Mechanisms Found in Silico and in Genetic Models of N588K-hERG Linked Short QT Syndrome

Hancox, J. C., Zhang, Y., Du, C. & Zhang, H., 30 Mar 2020, In : Journal of Integrative Cardiology Open Access. 3, 1, 4 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
27 Downloads (Pure)

Coronin 1 is required for integrin β2 translocation in platelets

Riley, D. R. J., Khalil, J. S., Pieters, J., Naseem, K. M. & Rivero, F., 5 Jan 2020, In : International Journal of Molecular Sciences. 21, 1, 20 p., 356.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
33 Downloads (Pure)

Cortical cells are altered by factors including bone morphogenetic protein released from a placental barrier model under altered oxygenation

Leinster, V. H. L., Phillips, T. J., Jones, N., Sanderson, S., Simon, K., Hanley, J. & Case, C. P., 9 Apr 2020, In : Neuronal Signaling. 4, 1, 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Downloads (Pure)
Open Access
File
50 Downloads (Pure)

Derivation of age-adjusted LACE index thresholds in the prediction of mortality and frequent hospital readmissions in adults

Fry, C. H., Heppleston, E., Fluck, D. & Han, T. S., 9 Jul 2020, (Accepted/In press) In : Internal and emergency medicine.

Research output: Contribution to journalArticle (Academic Journal)

Distinct Populations of Neurons Activated by Heroin and Cocaine in the Striatum as Assessed by catFISH

Vassilev, P., Avvisati, R., Koya, E. & Badiani, A., 16 Jan 2020, In : eNeuro. 7, 1

Research output: Contribution to journalArticle (Academic Journal)

Dop1R1, a type 1 dopaminergic receptor expressed in Mushroom Bodies, modulates Drosophila larval locomotion

Silva, B., Hidalgo, S. & Campusano, J. M., 26 Feb 2020, In : PLoS ONE.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
22 Downloads (Pure)

Early childhood general anesthesia and neurodevelopmental outcomes in the ALSPAC birth cohort

Walkden, G., Gill, H., Davies, N. M., Peters, A. E., Wright, I. & Pickering, A. E., 27 Jul 2020, (Accepted/In press) In : Anesthesiology.

Research output: Contribution to journalArticle (Academic Journal)

Efficacy of Electrical Baroreflex Activation Is Independent of Peripheral Chemoreceptor Modulation

Heusser, K., Thöne, A., Lipp, A., Menne, J., Beige, J., Reuter, H., Hoffmann, F., Halbach, M., Eckert, S., Wallbach, M., Koziolek, M., Haarmann, H., Joyner, M. J., Paton, J. F. R., Diedrich, A., Haller, H., Jordan, J. & Tank, J., 1 Jan 2020, In : Hypertension. 75, 1, p. 257-264 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Enhancing respiratory sinus arrhythmia increases cardiac output in rats with left ventricular dysfunction

O'Callaghan, E. L., Lataro, R. M., Roloff, E. L., Chauhan, A. S., Salgado, H. C., Duncan, E., Nogaret, A. & Paton, J. F. R., 1 Feb 2020, In : Journal of Physiology. 598, 3, p. 455-471 17 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

Epigenetic Link Between Statin Therapy and Type 2 Diabetes

Ochoa-Rosales, C., Portilla-Fernandez, E., Nano, J., Wilson, R., Lehne, B., Mishra, P. P., Gao, X., Ghanbari, M., Rueda-Ochoa, O. L., Juvinao-Quintero, D., Loh, M., Zhang, W., Kooner, J. S., Grabe, H. J., Felix, S. B., Schöttker, B., Zhang, Y., Gieger, C., Müller-Nurasyid, M., Heier, M. & 12 others, Peters, A., Lehtimäki, T., Teumer, A., Brenner, H., Waldenberger, M., Ikram, M. A., van Meurs, J. B. J., Franco, O. H., Voortman, T., Chambers, J., Stricker, B. H. & Muka, T., 7 Feb 2020, In : Diabetes Care.

Research output: Contribution to journalArticle (Academic Journal)

Expert consensus on low-calorie sweeteners: facts, research gaps and suggested actions

Ashwell, M., Gibson, S., Bellisle, F., Buttriss, J., Drewnowski, A., Fantino, M., Gallagher, A. M., de Graaf, K., Goscinny, S., Hardman, C. A., Laviada-Molina, H., López-García, R., Magnuson, B., Mellor, D., Rogers, P. J., Rowland, I., Russell, W., Sievenpiper, J. L. & la Vecchia, C., 13 Jan 2020, In : Nutrition Research Reviews. p. 1-10 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
45 Downloads (Pure)

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

Consortium for Refractive Error and Myopia (CREAM), 19 Mar 2020, In : Communications Biology. 3, 1, p. 133

Research output: Contribution to journalArticle (Academic Journal)

Hypertension, Antihypertensive Use and the Delayed-Onset of Huntington's Disease

Steventon, J. J., Rosser, A. E., Hart, E. & Murphy, K., 4 Feb 2020, In : Movement Disorders. 7, 3, 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
30 Downloads (Pure)

ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?

Vahabi, B., Jabr, R., Fry, C., McCloskey, K., Everaert, K., Agudelo, C. W., Monaghan, T. F., Rahnama'i, M. S., Panicker, J. N. & Weiss, J. P., 10 Jan 2020, In : Neurourology and Urodynamics. 8 p.

Research output: Contribution to journalReview article (Academic Journal)

Identification of PtdIns(3,4)P2 effectors in human platelets using quantitative proteomics

Durrant, T. N., Moore, S. F., Bayliss, A. L., Jiang, Y., Aitken, E. W., Wilson, M. C., Heesom, K. J. & Hers, I., 1 Feb 2020, In : Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1865, 2, 12 p., 158575.

Research output: Contribution to journalArticle (Academic Journal)

File
135 Downloads (Pure)

Increased apelin receptor gene expression in the subfornical organ of spontaneously hypertensive rats.

Griffiths, P. R., Lolait, S. J., Bijabhai, A., O'Carroll-Lolait, A., Paton, J. F. R. & O'Carroll, A-M., 21 Apr 2020, In : PLoS ONE.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
35 Downloads (Pure)

Inhibition of voltage-gated Na+ currents by eleclazine in rat atrial and ventricular myocytes

Caves, R. E., Carpenter, A., Choisy, S. C. M., Clennell, B., Cheng, H., McNiff, C., Mann, B., Milnes, J. T., Hancox, J. C. & James, A. F., 19 May 2020, (Accepted/In press) In : Heart Rhythm O2.

Research output: Contribution to journalArticle (Academic Journal)

In situ cryo-electron tomography reveals filamentous actin within the microtubule lumen

Paul, D. M., Mantell, J. M., Borucu, U., Coombs, J., Surridge, K. J., Squire, J. M., Verkade, P. & Dodding, M. P., 1 Jun 2020, In : Journal of Cell Biology. 219, 9, 14 p., e201911154.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
24 Downloads (Pure)

Integrity of corpus callosum is essential for the cross-hemispheric propagation of sleep slow waves: a high-density EEG study in split-brain patients

Avvenuti, G., Handjaras, G., Betta, M., Cataldi, J., Imperatori, L. S., Lattanzi, S., Riedner, B., Pietrini, P., Ricciardi, E., Tononi, G., Siclari, F., Polonara, G., Fabri, M., Silvestrini, M., Bellesi, M. & Bernardi, G., 15 Jul 2020, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 40, 29, p. 5589-5603 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Downloads (Pure)

Interneuron-specific plasticity at parvalbumin and somatostatin inhibitory synapses onto CA1 pyramidal neurons shapes hippocampal output

Udakis, M., Pedrosa, V., Chamberlain, S. E. L., Clopath, C. & Mellor, J. R., 31 Jul 2020, (Accepted/In press) In : Nature Communications.

Research output: Contribution to journalArticle (Academic Journal)

Interventions to treat pain in paediatric CFS/ME: a systematic review

Ascough, C., King, H., Serafimova, T., Beasant, L., Jackson, S., Baldock, L., Pickering, A. E., Brooks, J. & Crawley, E., 2020, In : BMJ Paediatrics Open . 4, 1, p. e000617

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
39 Downloads (Pure)

Investigating the associations of mucosal P2Y6 receptor expression and urinary ATP and ADP concentrations, with symptoms of overactive bladder

Firouzmand, S., Ajori, L., Towse, J., Allameh, F., Najafi, S., Javed, S., John, B., Langley, S., Fry, C. H. & Young, J., 12 Feb 2020, In : Neurourology and Urodynamics. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Investigation and treatment of high blood pressure in young people. Too much medicine or appropriate risk reduction

Hinton, T. C., Adams, Z. H., Baker, R. P., Hope, K., Paton, J. F. R., Hart, E. C. J. & Nightingale, A. K., 1 Jan 2020, In : Hypertension. 75, 1, p. 16–22 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
40 Downloads (Pure)

Ion currents, action potentials and noradrenergic responses in rat pulmonary vein and left atrial cardiomyocytes

Bond, R. C., Choisy, S. C., Bryant, S. M., Hancox, J. C. & James, A. F., 13 May 2020, In : Physiological Reports. 8, 9, 16 p., e14432.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
13 Downloads (Pure)

Keeping time in the lamina terminals: Novel oscillator properties of forebrain sensory circumventricular organs

Northeast, R. C., Chrobok, L., Hughes, A. T. L., Petit, C. & Piggins, H. D., 3 Jan 2020, In : FASEB Journal. 34, 1, p. 974-987 14 p., 201901111R.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
42 Downloads (Pure)

LACE index predicts age-specific unplanned readmissions and mortality after hospital discharge

Heppleston, E., Fry, C. H., Kelly, K., Shepherd, B., Wright, R., Jones, G., Robin, J., Murray, P., Fluck, D. & Han, T. S., 5 Jun 2020, In : Aging Clinical and Experimental Research. 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
8 Downloads (Pure)

Locus-coeruleus norepinephrine activity mediates sensory-evoked awakenings from sleep

Hayat, H., Regev, N., Matosevich, N., Sales, A. C., Paredes, E., Krom, A., Bergman, L., Li, Y., Lavigne, M., Kremer, E. J., Yizhar, O., Pickering, A. E. & Nir, Y., 8 Apr 2020, In : Science Advances. 6, 5, eaaz4232.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
23 Downloads (Pure)

Modulating the release of pharmaceuticals from lipid cubic phases using a lipase inhibitor

Dully, M., Brasnett, C., Djeghader, A., Seddon, A., Neilan, J., Murray, D., Butler, J., Soulimane, T. & Hudson, S. P., 1 Aug 2020, In : Journal of Colloid and Interface Science. 573, p. 176-192 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
20 Downloads (Pure)

Monoallelic loss-of-function THPO variants cause heritable thrombocytopenia

Cornish, N., Aungraheeta, M. R., FitzGibbon, L., Burley, K., Alibhai, D., Collins, J., Greene, D., Downes, K., NIHR BioResource, Westbury, S. K., Turro, E. & Mumford, A. D., 10 Mar 2020, In : Blood Advances. 4, 5, p. 920-924 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Downloads (Pure)

Morphine-induced respiratory depression is independent of β-arrestin2 signalling

Kliewer, A., Gillis, A., Hill, R., Schmidel, F., Bailey, C., Kelly, E., Henderson, G., Christie, M. J. & Schulz, S., 12 Feb 2020, In : British Journal of Pharmacology.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
32 Downloads (Pure)
Open Access
File
23 Downloads (Pure)