Stem Cells and Neuroregeneration Research Group

  • BS2 8DZ

    United Kingdom

Organization profile

Organisation profile

Molecular, imaging and sophisticated viral delivery techniques are used to investigate the genes that regulate neuronal function. This work includes: 
 
  1. identifying the changes in gene expression that occur in neuronal cells exposed to stress or disease causing agent; 
  2. developing viral vector systems optimized to study neuronal function; 
  3. developing stem cell and induced pluripotent stem cell models of human disease conditions; 
  4. how miRNAs and RNA binding proteins influence the expression of genes involved in the control of fundamental neuronal processes.

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    Research Output

  • A monolayer hiPSC culture system for autophagy/mitophagy studies in human dopaminergic neurons

    Stathakos, P., Jiménez Moreno, N., Crompton, L. A., Nistor, P. A., Badger, J. L., Barbuti, P. A., Kerrigan, T. L., Randall, A. D., Caldwell, M. A. & Lane, J. D., 23 Jan 2020, (Accepted/In press) In : Autophagy.

    Research output: Contribution to journalArticle (Academic Journal)

  • Open Access
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    Projects

    ERAC

    Uney, J. B.

    1/02/091/02/12

    Project: Research

    Student theses

    A Viral Approach to Translatome Profiling of CA1 Neurons During Associative Recognition Memory Formation

    Author: Gaunt, J., 25 Sep 2018

    Supervisor: Uney, J. (Supervisor), Warburton, C. (Supervisor) & Marucci, L. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Developing regulatable lentiviral vectors for the treatment of nerve injuries and Parkinson’s disease

    Author: Houghton, B., 14 May 2013

    Supervisor: Wong, L. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Examining the Role of Placental-derived MicroRNA Secretions in Response to Gestational Hypoxia on Foetal Neurodevelopment

    Author: Bignell, A. L., 23 Jan 2020

    Supervisor: Case, C. P. (Supervisor), Perks, C. M. (Supervisor), Uney, J. B. (Supervisor) & Fulga, T. A. (External person) (Supervisor)

    Student thesis: Master's ThesisMaster of Science (MSc)

    File