• United Kingdom

Organization profile

Organisation profile

Chemical synthesis, the conversion of simple materials into complex products, underpins a multitude of research encompassing organic, inorganic, materials and biological chemistry. The broad ranging pursuit includes the synthesis of complex natural products, the development of new organocatalytic and organometallic processes, the use of photochemical flow technologies for the construction of unique-molecular space, the synthesis of unusual sugars, and the synthesis of novel "drug like" scaffolds to understand the impact of chirality on biological interactions.  Synthetic isotopic labeling techniques are employed to establish natural product structure, biological pathways and provide biomedical diagnostics. Peptide-carbohydrate hybrid materials are being developed for applications in tissue engineering and regenerative medicine. Methods for creating molecules and assemblies with bio-inspired function are being pursued.

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  • Network Recent external collaboration on country level. Dive into details by clicking on the dots.

    Research Output

    1,3-Difunctionalizations of [1.1.1]Propellane via 1,2-Metallate Rearrangements of Boronate Complexes

    Yu, S., Jing, C., Noble, A. & Aggarwal, V. K., 2 Mar 2020, In : Angewandte Chemie - International Edition. 59, 10, p. 3917-3921 6 p.

    Research output: Contribution to journalArticle (Academic Journal)

  • 5 Citations (Scopus)

    A Bioinspired Strategy for the Enantioselective Synthesis of Bicyclic Oxygen Heterocycles

    Rodriguez Venegas, E. & Willis, C. L., 16 Mar 2020, In : Organic Letters. 5 p.

    Research output: Contribution to journalArticle (Academic Journal)

  • ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

    Evans, C., Miners, J. S., Piva, G., Willis, C. L., Heard, D. M., Kidd, E. J., Good, M. & Kehoe, P. G., 25 Jan 2020, In : Acta Neuropathologica. 18 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 44 Downloads (Pure)

    Projects

    BrisSynBio / SAGE Vaccines

    Woolfson, D. N.

    13/10/1412/10/21

    Project: Research

    Supervised learning to support the optimisation of chemical reactions

    Fey, N. & Swallow, B. T.

    17/04/1731/07/17

    Project: Research

    Student theses

    Augmenting photosynthesis to enhance crop productivity using carbon dots

    Author: Swift, T., 23 Jan 2019

    Supervisor: Galan, C. (Supervisor) & Whitney, H. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Catalytic Dehydropolymerisation of Amine– and Phosphine–Boranes as a Route to Structurally Diverse Materials

    Author: Resendiz-Lara, D., 23 Jan 2019

    Supervisor: Manners, I. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    De novo designed protein-protein interaction domains for synthetic biology applications in cells

    Author: Edgell, C. L., 23 Jan 2019

    Supervisor: Woolfson, D. (Supervisor) & Savery, N. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Prizes

    Royal Society Wolfson Research Merit Award

    Jeremy Harvey (Recipient), 2014

    Prize: Prizes, Medals, Awards and Grants

  • Activities

    Sanjib Patra

    Charl F J Faul (Host), , Ian Manners (Host), , Natalie Fey (Host), & Simon Burbidge (Host)

    23 Jul 201930 Jul 2019

    Activity: Hosting a visitor typesHosting an academic visitor

    Inaugural Bristol BioDesign Institute Conference

    Kathleen R Sedgley (Participant), , Dek Woolfson (Organiser), , Imre Berger (Organiser), , Katharina Landfester (Keynote/plenary speaker), & Nadrian Seeman (Keynote/plenary speaker)

    10 May 2018

    Activity: Participating in or organising an event typesParticipation in conference

    File

    Computationally Directed Protein Design Workshop

    Dek Woolfson (Participant), , Fabio Parmeggiani (Participant), , Ross Anderson (Participant), , Kathleen Sedgley (Participant), & Tom Bowker (Participant)

    2018

    Activity: Participating in or organising an event typesParticipation in workshop, seminar, course