20052020

Research output per year

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Personal profile

Research interests

  • The role of hypoxia (reduced tissue oxygen levels) in the tumour microenvironment
  • Signal transduction pathways in cancer development (particularly Wnt/β-catenin and Hippo-YAP/TAZ)
  • The role of autophagy in tissue homeostasis and cancer
  • Apoptosis and tumour cell survival 
  • Cyclooxygenases (COX1 and COX2) and prostaglandins (particularly PGE2)
  • Three-dimensional models of normal and cancer tissue (spheroid & organoid culture)
  • Post-translational modifications and cancer epigenetics
  • Drug resistance & novel targets for cancer therapy 

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