Research output per year
Research output per year
Personal profile
Research interests
- The role of hypoxia (reduced tissue oxygen levels) in the tumour microenvironment
- Signal transduction pathways in cancer development (particularly Wnt/β-catenin and Hippo-YAP/TAZ)
- The role of autophagy in tissue homeostasis and cancer
- Apoptosis and tumour cell survival
- Cyclooxygenases (COX1 and COX2) and prostaglandins (particularly PGE2)
- Three-dimensional models of normal and cancer tissue (spheroid & organoid culture)
- Post-translational modifications and cancer epigenetics
- Drug resistance & novel targets for cancer therapy
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Transcriptomic analyses of MYCN-regulated genes in anaplastic Wilms' tumour cell lines reveals oncogenic pathways and potential therapeutic vulnerabilities
Szemes, M., Melegh, Z. B., Bellamy, J. S., Greenhough, A., Catchpoole, D. & Malik, K. T. A., 6 Feb 2021, In: Cancers. 13, 4, p. 1-21 21 p., 656.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)121 Downloads (Pure) -
A combined proteomics and Mendelian randomization approach to investigate the effects of aspirin-targeted proteins on colorectal cancer
Nounu, A., Greenhough, A., Heesom, K. J., Richmond, R. C., Zheng, J., Weinstein, S. J., Albanes, D., Baron, J. A., Melbourne, J. L., Figueiredo, J. C., Newcomb, P. A., Lindor, N. M., Casey, G., Platz, E. A., Le Marchand, L., Ulrich, C. M., Li, C. I., van Duijnhoven, F. J. B., Gsur, A., Campbell, P., & 42 others, 14 Dec 2020, (E-pub ahead of print) In: Cancer Epidemiology, Biomarkers and Prevention.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile8 Citations (Scopus)71 Downloads (Pure) -
A Wnt-BMP4 Signaling Axis Induces MSX and NOTCH Proteins and Promotes Growth Suppression and Differentiation in Neuroblastoma
Szemes, M., Bellamy, J., Melegh, Z., Greenhough, A., Kollareddy, M., Catchpoole, D. & Malik, K., 23 Mar 2020, In: Cells. 9, 3, 18 p., 783.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile8 Citations (Scopus)146 Downloads (Pure)
Prizes
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Academy of Medical Sciences Poster & Presentation Prize (Finalist)
Greenhough, Alex (Recipient), May 2017
Prize: Prizes, Medals, Awards and Grants
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BACR Prize for Best Overall Presentation
Greenhough, Alex (Recipient), Jul 2016
Prize: Prizes, Medals, Awards and Grants
Activities
- 1 Public talk, debate, discussion
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Invited interview broadcast on BBC Radio Bristol (5pm, 24th August 2018)
Alexander Greenhough (Advisor)
24 Aug 2018Activity: Talk or presentation types › Public talk, debate, discussion