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My research interests are broadly around understanding the immunology of infectious diseases with a translational focus. I am currently working on using new technologies to understand Group A streptococcal biology in individuals with either asymptomatic carriage or pharyngitis. Using samples from infected individuals, I hope to better understand the bacterial and immunological processes which occur in natural infection and disease, to inform vaccine development. I was recently awarded a 2 year Elizabeth Blackwell Institute Early Career Fellowship to carry out this project, with the support of Professor Adam Finn.
I also maintain an interest in several other infectious diseases, including a number of important respiratory pathogens. I previously worked on the immunodiagnosis of Tuberculosis infection in Imperial College London (with Prof. Ajit Lalvani), in a large project using samples from patients recruited with suspect active Tuberculosis in the UK. I also worked on signatures of progression risk within those with latent Tuberculosis infection. Whilst at Imperial College I also spent some time on a project to describe the immune responses to the live attenuated influenza vaccine in children. My doctorate was in the field of parasite immunology using mouse models of infection. Recently, I have been involved in several projects exploring the immune responses to SARS-CoV-2 infection and different COVID-19 vaccines.
I am very interested in better understanding the immunobiology of infectious diseases using clinical studies, in order to develop improved vaccines, diagnostics and treatments.
Honorary Research Associate, Imperial College London
1 Oct 2018 → …
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1/10/18 → 30/09/20
Halliday, A., Long, A. E., Baum, H. E., Thomas, A., Shelley, K. L., Oliver, E. H., Gupta, K., Francis, O., Kavanagh Williamson, M., Di Bartolo, N. D., Randell, M. J., Ben Khoud, Y., Kelland, I., Mortimer, G. L. M., Ball, O. E., Plumptre, C., Chandler, M. A., Obst, U., Secchi, M., Piemonti, L., & 27 others, 9 Nov 2022, In: Frontiers in Immunology. 13, 20 p., 968317.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile1 Citation (Scopus)29 Downloads (Pure)
Halliday, A., Masonou, T., Tolosa-Wright, M. R., Guo, Y., Hoang, L., Parker, R., Boakye, A., Takwoingi, Y., Badhan, A., Jain, P., Marwah, I., Berrocal-Almanza, L. C., Deeks, J. J., Beverley, P., Kon, O. M. & Lalvani, A., 31 Jul 2021, (E-pub ahead of print) In: Journal of Infectious Diseases. 10 p., jiab311.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile2 Citations (Scopus)28 Downloads (Pure)
Transcriptomic signatures for diagnosing tuberculosis in clinical practice: a prospective, multicentre cohort studyHoang, L. T., Jain, P., Pillay, T. D., Tolosa-Wright, M., Niazi, U., Takwoingi, Y., Halliday, A., Berrocal-Almanza, L. C., Deeks, J. J., Beverley, P., Kon, O. M. & Lalvani, A., Mar 2021, In: Lancet Infectious Diseases. 21, 3, p. 366-375 10 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile23 Citations (Scopus)52 Downloads (Pure)
Oliver, J. (Creator), Oliver, E. (Creator), Thomas, A. (Creator), Halliday, A. (Creator), Goenka, A. (Creator), Baum, H. (Creator), Gillespie, K. M. (Creator), Long, A. E. (Creator), Toye, A. M. (Creator) & Finn, A. H. R. (Creator), University of Bristol, 28 Sept 2022
Evaluation and deployment of isotype-specific salivary antibody assays for detecting previous SARS-CoV-2 infection in children and adults
Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2. Goenka et al