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My research interests are broadly around understanding the immunology of infectious diseases with a translational focus. I am currently working on using new technologies to understand Group A streptococcal biology in individuals with either asymptomatic carriage or pharyngitis. Using samples from infected individuals, I hope to better understand the bacterial and immunological processes which occur in natural infection and disease, to inform vaccine development. I was recently awarded a 2 year Elizabeth Blackwell Institute Early Career Fellowship to carry out this project, with the support of Professor Adam Finn.
I also maintain an interest in several other infectious diseases, including a number of important respiratory pathogens. I previously worked on the immunodiagnosis of Tuberculosis infection in Imperial College London (with Prof. Ajit Lalvani), in a large project using samples from patients recruited with suspect active Tuberculosis in the UK. I also worked on signatures of progression risk within those with latent Tuberculosis infection. Whilst at Imperial College I also spent some time on a project to describe the immune responses to the live attenuated influenza vaccine in children. My doctorate was in the field of parasite immunology using mouse models of infection.
I am very interested in better understanding the immunobiology of infectious diseases using clinical studies, in order to develop improved vaccines, diagnostics and treatments.
Honorary Research Associate, Imperial College London
1 Oct 2018 → …
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- 2 Finished
1/10/18 → 30/09/20
Halliday, A., Masonou, T., Tolosa-Wright, M. R., Guo, Y., Hoang, L., Parker, R., Boakye, A., Takwoingi, Y., Badhan, A., Jain, P., Marwah, I., Berrocal-Almanza, L. C., Deeks, J. J., Beverley, P., Kon, O. M. & Lalvani, A., 31 Jul 2021, (E-pub ahead of print) In: Journal of Infectious Diseases. 10 p., jiab311.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile8 Downloads (Pure)
Halliday, A., Jain, P., Hoang, L., Parker, R., Tolosa-Wright, M., Masonou, T., Green, N., Boakye, A., Takwoingi, Y., Hamilton, S., Mandagere, V., Fries, A., Coin, L., Deeks, J., White, P. J., Levin, M., Beverley, P., Kon, O. M. & Lalvani, A., 13 Apr 2021, In: Efficacy and Mechanism Evaluation. 8, 5
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile17 Downloads (Pure)
Predisposing factors to acquisition of acute respiratory tract infections in the community: a systematic review and meta‑analysisHammond, A., Halliday, A., Thornton, H. V. & Hay, A. D., 14 Dec 2021, In: BMC Infectious Diseases. 21, 11 p., 1254 .
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile3 Downloads (Pure)
Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2. Goenka et al