Projects per year
My research interests are broadly around understanding the immunology of infectious diseases with a translational focus. I am currently working on using new technologies to understand Group A streptococcal biology in individuals with either asymptomatic carriage or pharyngitis. Using samples from infected individuals, I hope to better understand the bacterial and immunological processes which occur in natural infection and disease, to inform vaccine development. I was recently awarded a 2 year Elizabeth Blackwell Institute Early Career Fellowship to carry out this project, with the support of Professor Adam Finn.
I also maintain an interest in several other infectious diseases, including a number of important respiratory pathogens. I previously worked on the immunodiagnosis of Tuberculosis infection in Imperial College London (with Prof. Ajit Lalvani), in a large project using samples from patients recruited with suspect active Tuberculosis in the UK. I also worked on signatures of progression risk within those with latent Tuberculosis infection. Whilst at Imperial College I also spent some time on a project to describe the immune responses to the live attenuated influenza vaccine in children. My doctorate was in the field of parasite immunology using mouse models of infection.
I am very interested in better understanding the immunobiology of infectious diseases using clinical studies, in order to develop improved vaccines, diagnostics and treatments.
Honorary Research Associate, Imperial College London1 Oct 2018 → …
Structured keywords and research groupings
1/10/18 → 30/09/20
Halliday, A., Jain, P., Hoang, L., Parker, R., Tolosa-Wright, M., Masonou, T., Green, N., Boakye, A., Takwoingi, Y., Hamilton, S., Mandagere, V., Fries, A., Coin, L., Deeks, J., White, P. J., Levin, M., Beverley, P., Kon, O. M. & Lalvani, A., 13 Apr 2021, In: Efficacy and Mechanism Evaluation. 8, 5
Research output: Contribution to journal › Article (Academic Journal) › peer-review
Transcriptomic signatures for diagnosing tuberculosis in clinical practice: a prospective, multicentre cohort studyHoang, L. T., Jain, P., Pillay, T. D., Tolosa-Wright, M., Niazi, U., Takwoingi, Y., Halliday, A., Berrocal-Almanza, L. C., Deeks, J. J., Beverley, P., Kon, O. M. & Lalvani, A., Mar 2021, In: Lancet Infectious Diseases. 21, 3, p. 366-375 10 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile1 Citation (Scopus)5 Downloads (Pure)
Eosinophil-Mediated Immune Control of Adult Filarial Nematode Infection Can Proceed in the Absence of IL-4 Receptor SignalingPionnier, N., Sjoberg, H., Furlong-Silva, J., Marriott, A., Halliday, A., Archer, J., Steven, A., Taylor, M. J. & Turner, J. D., 1 Aug 2020, In: Journal of Immunology. 205, 3, p. 731-740 10 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile8 Downloads (Pure)
Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2. Goenka et al