Mr Alistair J K Williams

B.Sc.(York), F.I.M.L.S.

  • BS10 5NB

1989 …2020

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Personal profile

Research interests

Alistair has worked in diabetes research since 1986, when he joined the group led by Professor Edwin Gale at St. Bartholomew’s hospital. Initially, working in the laboratory running insulin and C-peptide assays for the BOX study, he then spent time working on a project investigating Islet Amyloid Polypeptide and assisting Dr. Paolo Pozzili in testing agents aimed at preventing diabetes in the NOD mouse. In 1993, Alistair took over responsibility for the day to day running of the ENDIT islet cell antibody reference laboratory and subsequently the islet autoantibody assay laboratory. During this period he was responsible for development of the micro insulin autoantibody assay, which is now the method of choice for measuring insulin antibodies in children. In 1997, Alistair moved to Bristol with the team and has continued to supervise the autoantibody assay laboratory under Professor Polly Bingley and has been closely involved in international efforts to standardise autoantibody measurement. Recently, Alistair has developed his interest in pancreatic imaging with projects aimed at characterising pancreas size in diabetes.

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Research Output

Hierarchical order of distinct autoantibody spreading and progression to type 1 diabetes in the TEDDY Study

Vehik, K., Bonifacio, E., Yu, L., Williams, A. J. K., Schatz, D., Rewers, M., She, J-X., Toppari, J., Hagopian, W., Akolkar, B., Ziegler, A-G., Krischer, J. & The TEDDY Study Group, 8 Jul 2020, In : Diabetes Care. 8 p., dc192547.

Research output: Contribution to journalArticle (Academic Journal)

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    Type 1 diabetes in Africa: an immunogenetic study in the Amhara of North-West Ethiopia

    Balcha, S. A., Demisse, A. G., Mishra, R., Vartak, T., Cousminer, D. L., Hodge, K. M., Voight, B. F., Lorenz, K., Schwartz, S., Jerram, S. T., Gamper, A., Holmes, A., Wilson, H. F., Williams, A. J. K., Grant, S. F. A., Leslie, R. D., Phillips, D. I. W. & Trimble, E. R., 23 Jul 2020, In : Diabetologia. 11 p.

    Research output: Contribution to journalArticle (Academic Journal)

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    Supervised Work

    Beta cell loss in autoimmune diabetes: a useful clinical biomarker of disease progression?

    Author: Alrashidi, F., 6 Nov 2018

    Supervisor: Gillespie, K. (Supervisor) & Williams, A. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

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