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Dr Aliya SarmanovaPhD, MSc, MD

Research Associate

Aliya Sarmanova

Dr Aliya SarmanovaPhD, MSc, MD

Research Associate

Member of

Research interests

Dr Aliya Sarmanova is a Research Associate in Musculoskeletal and Clinical Outcomes working on the Wellcome Trust funded AUGMENT project. Her current research is focused on deriving joint shape and osteoarthritis-related features (i.e. osteophytes, joint space narrowing, subchondral sclerosis) using statistical shape modelling (SSM) on knee DXA scans obtained in UK Biobank.
Other current projects include investigating confounding by population structure in genetic studies and causal inference (UK Biobank), and the association between genetic predisposition to osteoarthritis and musculoskeletal pain in adolescents (ALSPAC, GO Consortium).

Aliya’s previous research was on osteoarthritis phenotypes including “inflammatory” changes in knee synovium detected by ultrasound and contribution of central pain mechanisms to knee pain severity and progression (Arthritis Research UK Pain Cetre), the effect of statins on risk of joint replacement (collaboration with Central South University in China), gout treatment (randomised controlled trial comparing nurse-led optimal care to general practitioner led usual care for people with gout, the Lancet, 2018).

Aliya’s research interests include musculoskeletal epidemiology (osteoarthritis, gout, rheumatoid arthritis and fibromyalgia), big data analysis (CPRD, UK Biobank), causal inference (e.g. risk factors, pain mechanisms, placebo response), application of imaging (i.e. ultrasound, radiographs, DXA), clinical trials and genetics (heritability, GWAS, mendelian randomization).

Biography

Aliya graduated with a first class diploma (hons) in Internal Medicine in 2009 from the Astana Medical University, Kazakhstan. She completed rheumatologist training and worked in hospital and outpatient centre for 4 years in Kazakhstan.

Her research career started in 2014 when she was awarded a prestigious Bolashak PhD scholarship with the Kazakhstan Government (2014-2017). Aliya completed her PhD in synovial changes on knee ultrasound in people with knee pain and the general population in the University of Nottingham.

View research connections

Postal address:
Musculoskeletal Research Unit
University of Bristol
Level 1 Learning and Research Building
Southmead Hospital
Westbury-on-Trym, Bristol
United Kingdom