Professor Andrew David Dick

B.Sc., M.B.B.S.(Lond.), M.D.(Aberd.), M.R.C.P.(UK), F.R.C.S.(Lond.), F.R.C.S.(Edin.), F.R.C.P.(Edin.), F.R.C.Ophth, FMedSci

  • BS1 2LX

19962020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Activation of C-Reactive Protein Proinflammatory Phenotype in the blood retinal barrier in vitro: Implications for Age-related Macular Degeneration

Romero-Vázquez, S., Adán, A., Figueras-Roca, M., Llorenç, V., Slevin, M., Vilahur, G., Badimon, L., Dick, A. D. & Molins, B., 16 Jul 2020, In : Aging. 12, 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
15 Downloads (Pure)

Areas of agreement in the management of childhood non-infectious chronic anterior uveitis in the UK

POIG Uveitis Delphi Group, 1 Jan 2020, In : British Journal of Ophthalmology. 104, 1, p. 11-16 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
202 Downloads (Pure)

Features of ectopic lymphoid-like structures in human uveitis

Epps, S. J., Coplin, N., Luthert, P. J., Dick, A. D., Coupland, S. E. & Nicholson, L. B., 1 Feb 2020, In : Experimental Eye Research. 191, 9 p., 107901.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
59 Downloads (Pure)

Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 disruption using CRISPR-Cas9

Wu, J., Bell, O. H., Copland, D. A., Young, A., Pooley, J. R., Maswood, R., Evans, R. S., Khaw, P., Ali, R. R., Dick, A. D. & Chu, C. J., 9 Jan 2020, In : Molecular Therapy. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
86 Downloads (Pure)

Intravenous indocyanine green dye is insufficient for robust immune cell labelling in the human retina

Bell, O. H., Carreño, E., Williams, E. L., Wu, J., Copland, D. A., Bora, M., Kobayter, L., Fruttiger, M., Sim, D. A., Lee, R. W. J., Dick, A. D. & Chu, C. J., 13 Feb 2020, In : PLoS ONE. 15, 2, 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
51 Downloads (Pure)

Personal Protective Equipment (PPE) for Vitreoretinal Surgery During COVID-19

Chandra, A., Haynes, R. J., Burdon, M., Laidlaw, A., Neffendorf, J. E., Eames, I., da Cruz, L., Lee, R. W. J., Charles, S. J., Wilson, P. W. M., Dick, A. D., Flanagan, D., Yorston, D., Hingorani, M. & Wickham, L., 12 May 2020, In : Eye. 4 p.

Research output: Contribution to journalComment/debate (Academic Journal)

Open Access
File
91 Downloads (Pure)

Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial

APTITUDE Trial Management Group, 7 Feb 2020, In : The Lancet Rheumatology. 2, 3, p. e135-e141 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
21 Downloads (Pure)

Treatment of diabetic retinopathy through neuropeptide Y-mediated enhancement of neurovascular microenvironment

Ou, K., Copland, D. A., Theodoropoulou, S., Mertsch, S., Liu, J., Li, Y., Schrader, S., Liu, L. & Dick, A. D., 6 Mar 2020, In : Journal of Cellular and Molecular Medicine. 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
47 Downloads (Pure)
2019

Adalimumab in combination with methotrexate for refractory uveitis associated with juvenile idiopathic arthritis: a RCT

Ramanan, A. V., Dick, A. D., Jones, A. P., Hughes, D. A., McKay, A., Rosala-Hallas, A., Williamson, P. R., Hardwick, B., Hickey, H., Rainford, N., Hickey, G., Kolamunnage-Dona, R., Culeddu, G., Plumpton, C., Wood, E., Compeyrot-Lacassagne, S., Woo, P., Edelsten, C. & Beresford, M. W., 1 Apr 2019, In : Health Technology Assessment. 23, 15, p. 1-140 140 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
114 Downloads (Pure)

Adalimumab in Juvenile Idiopathic Arthritis–Associated Uveitis: 5-Year Follow-up of the Bristol Participants of the SYCAMORE Trial

Horton, S., Jones, A. P., Guly, C., Hardwick, B., Beresford, M. W., Lee, R., Dick, A. & Ramanan, A., 1 Nov 2019, In : American Journal of Ophthalmology. 207, p. 170-174 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
26 Downloads (Pure)

A review and update on the Ophthalmic implications for Susac Syndrome

Heng, L. Z., Bailey, C., Lee, R., Dick, A. D. & Ross, A., 28 Jan 2019, In : Survey of Ophthalmology.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
111 Downloads (Pure)

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration

Handa, JT., Bowes Rickman, C., Dick, A., Gorin, M. B., Miller, J. W., Toth, C. A., Ueffing, M., Zarbin, M. & Farrer, L. A., 26 Jul 2019, In : Nature Communications. 10, 1, 11 p., 3347.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
18 Citations (Scopus)
119 Downloads (Pure)

Clinical spectrum of vitreoretinal lymphoma and its association with MyD88 L265P mutation

Carreno, E., Clench, T., Steeples, L. R., Salvatore, S., Lee, R. W. J., Dick, A. D. & Pawade, J., 1 Feb 2019, In : Acta Ophthalmologica. 97, 1, p. e138-e139

Research output: Contribution to journalLetter (Academic Journal)

4 Citations (Scopus)

Cohort profile: Design and methods in the eye and vision consortium of UK Biobank

UK Biobank Eye and Vision Consortium, 21 Feb 2019, In : BMJ Open. 9, 2, 13 p., e025077.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
8 Citations (Scopus)
126 Downloads (Pure)
Open Access
File
1 Citation (Scopus)
203 Downloads (Pure)

Corrigendum to "Restoring retinal neurovascular health via substance P" [Exp. Cell Res. (2019)]

Ou, K., Mertsch, S., Theodoropoulou, S., Wu, J., Liu, J., Copland, D. A., Schrader, S., Liu, L. & Dick, A. D., 15 Sep 2019, In : Experimental Cell Research. 382, 2, 1 p., 111482.

Research output: Contribution to journalComment/debate (Academic Journal)

Long-term efficacy and tolerability of TNFα inhibitors in the treatment of non-infectious ocular inflammation: an 8-year prospective surveillance study

Sharma, S. M., Damato, E., Hinchcliffe, A., Andrews, C. D., Myint, K., Lee, R. & Dick, A., 12 Mar 2019, In : British Journal of Ophthalmology.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
226 Downloads (Pure)

Management of paediatric ocular inflammatory disease in the UK: national survey of practice

Solebo, A. L., Rahi, J. S., Edelsten, C., Ashworth, J. L. & Dick, A., 9 Jul 2019, In : Eye.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
54 Downloads (Pure)

Modelling Macular Edema: The Effect of IL-6 and IL-6R Blockade on Human Blood-Retinal Barrier Integrity In Vitro

Mesquida, M., Drawnel, F., Lait, P. J., Copland, D. A., Stimpson, M. L., Llorenç, V., Sainz de la Maza, M., Adan, A., Widmer, G., Strassburger, P., Fauser, S., Dick, A. D., Lee, R. W. J. & Molins, B., 28 Oct 2019, In : Translational vision science & technology. 8, 5, 10 p., 32.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
96 Downloads (Pure)

Müller Cells Stabilize Microvasculature through Hypoxic Preconditioning.

Ou, K., Mertsch, S., Theodoropoulou, S., Wu, J., Liu, J., Copland, D., Scott, L., Dick, A., Schrader, S. & Liu, L., 25 Mar 2019, (Accepted/In press) In : Cellular Physiology and Biochemistry. 52, p. 668-680 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
146 Downloads (Pure)

Quantile regression analysis reveals widespread evidence for gene-environment or gene-gene interactions in myopia development

Pozarickij, A., Williams, C., Hysi, P. G., Guggenheim, J. A. & UK Biobank Eye and Vision Consortium, 6 May 2019, In : Communications Biology. 2, 8 p., 167 (2019).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
119 Downloads (Pure)

Reduced Macular Vessel Density and Capillary Perfusion in Glaucoma Detected Using OCT Angiography

Wu, J., Sebastian, R. T., Chu, C. J., McGregor, F., Dick, A. D. & Liu, L., 4 May 2019, In : Current Eye Research. 44, 5, p. 533-540 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
96 Downloads (Pure)

Restoring retinal neurovascular health via substance P

Ou, K., Mertsch, S., Theodoropoulou, S., Wu, J., Liu, J., Copland, D., Schrader, S., Liu, L. & Dick, A., 15 Jul 2019, In : Experimental Cell Research. 380, 2, p. 115-123 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
319 Downloads (Pure)

RNA-Seq Reveals Alterations in Homeostatic Microglial Function during Inflammation and Resolution

Bell, O. H., Copland, D. A., Ward, A., Chu, C. J., Lange, C. A. K. & Dick, A. D., 1 Jul 2019.

Research output: Contribution to conferenceConference Abstract

Open Access

Single Eye mRNA-Seq Identifies Heterogeneity in Retinal Microglial Function during Acute Inflammation

Bell, O., Copland, D. A., Ward, A., Chu, C. J., Nicholson, L. B., Lange, C. A. K. & Dick, A. D., 14 Oct 2019, (Accepted/In press).

Research output: Contribution to conferenceConference Poster

The Bromodomain and Extra-Terminal Protein Inhibitor OTX015 Suppresses T Helper Cell Proliferation and Differentiation

Hu, X., Schewitz-Bowers, L., Lait, P., Copland, D., Stimpson, M., Li, J. J., Liu, Y., Dick, A., Lee, R. & Wei, L., 25 Jan 2019, In : Current Molecular Medicine. 18, 9, p. 594-601 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
135 Downloads (Pure)

The Relationship Between Ambient Atmospheric Fine Particulate Matter (PM2.5) and Glaucoma in a Large Community Cohort.

Chua, S. Y. L., Khawaja, A. P., Morgan, J., Strouthidis, N., Reisman, C., Dick, A. D., Khaw, P. T., Patel, P. J. & Foster, PJ., 1 Nov 2019, In : Investigative Ophthalmology and Visual Science. 60, p. 4915 - 4923 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
83 Downloads (Pure)
2018

Adalimumab in Active and Inactive, Non-Infectious Uveitis: Global Results from the VISUAL I and VISUAL II Trials

Goto, H., Zako, M., Namba, K., Hashida, N., Kaburaki, T., Miyazaki, M., Sonoda, K. H., Abe, T., Mizuki, N., Kamoi, K., Brézin, A. P., Dick, A. D., Jaffe, G. J., Nguyen, Q. D., Inomata, N., Kwatra, N. V., Camez, A., Song, A. P., Kron, M., Tari, S. & 1 others, Ohno, S., 17 Jul 2018, In : Ocular Immunology and Inflammation. 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
205 Downloads (Pure)

A Perspective of AMD Through the Eyes of Immunology

Copland, D. A., Theodoropoulou, S., Liu, J. & Dick, A. D., 20 Jul 2018, In : Investigative Ophthalmology and Visual Science. 59, 4, p. AMD83-AMD92

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

A phase II trial protocol of Tocilizumab in anti-TNF refractory patients with JIA-associated uveitis (the APTITUDE trial)

APTITUDE Trial Management Group, 27 Feb 2018, In : BMC Rheumatology. 2, 4, 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
6 Citations (Scopus)
149 Downloads (Pure)

Autoimmunity, Autoinflammation, and Infection in Uveitis

Forrester, J. V., Kuffova, L. & Dick, A. D., 1 May 2018, In : American Journal of Ophthalmology. 189, p. 77-85 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
17 Citations (Scopus)
227 Downloads (Pure)

Automated quantification of retinal vessel morphometry in the UK biobank cohort

on behalf of the UK Biobank Eye and Vision Consortium, 8 Mar 2018, Proceedings of the 7th International Conference on Image Processing Theory, Tools and Applications, IPTA 2017. Institute of Electrical and Electronics Engineers (IEEE), Vol. 2018-January. p. 1-6 6 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

3 Citations (Scopus)

Bevacizumab for treatment of choroidal neovascularization secondary to candida chorioretinitis

Makragiannis, G., Vahdani, K., Carreño, E., Lee, R. W. J., Dick, A. D. & Ross, A. H., 1 Apr 2018, In : International Ophthalmology. 38, 2, p. 781-785 5 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
251 Downloads (Pure)

Combined immunosuppression and radiotherapy in thyroid eye disease (CIRTED): a multicentre, 2 × 2 factorial, double-blind, randomised controlled trial

Rajendram, R., Taylor, P. N., Wilson, V. J., Harris, N., Morris, O. C., Tomlinson, M., Yarrow, S., Garrott, H., Herbert, H. M., Dick, A. D., Cook, A., Gattamaneni, R., Jain, R., Olver, J., Hurel, S. J., Bremner, F., Drummond, S. R., Kemp, E., Ritchie, D. M., Rumsey, N. & 15 others, Morris, D., Lane, C., Palaniappan, N., Li, C., Pell, J., Hills, R., Ezra, D. G., Potts, M. J., Jackson, S., Rose, G. E., Plowman, N., Bunce, C., Uddin, J. M., Lee, R. W. J. & Dayan, C. M., 1 Apr 2018, In : Lancet Diabetes and Endocrinology. 6, 4, p. 299-309 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
21 Citations (Scopus)
246 Downloads (Pure)

Cost-Effectiveness Analysis of Adalimumab for the Treatment of Uveitis Associated with Juvenile Idiopathic Arthritis

Hughes, D. A., Culeddu, G., Plumpton, C., Wood, E., Dick, A., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Woo, P., Beresford, M. W. & Ramanan, A., 16 Oct 2018, In : Ophthalmology. 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
174 Downloads (Pure)

C-reactive protein as a therapeutic target in age-related macular degeneration

Molins, B., Romero-Vázquez, S., Fuentes-Prior, P., Adan, A. & Dick, A. D., 19 Apr 2018, In : Frontiers in Immunology. 9, APR, 9 p., 808.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
209 Downloads (Pure)

Efficacy and safety of intravitreal anti-tumour necrosis factor drugs in adults with non-infectious uveitis - a systematic review

Leal, I., Rodrigues, F. B., Sousa, D. C., Romão, V. C., Duarte, G. S., Carreño, E., Dick, A. D., Marques-Neves, C., Costa, J. & Fonseca, J. E., 25 Mar 2018, In : Acta Ophthalmologica.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
6 Citations (Scopus)
198 Downloads (Pure)

Genome-wide association meta-analysis highlights light-induced signaling as a driver for refractive error

The CREAM Consortium, the 23 and Me Research Team, UK Biobank Eye and Vision Consortium & Tedja, M. S., Jun 2018, In : Nature Genetics. 50, 6, p. 834-848 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
60 Citations (Scopus)
242 Downloads (Pure)

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis: Fundamentals Of Care for UveitiS (FOCUS) Initiative

Fundamentals of Care for Uveitis International Consensus Group, 1 May 2018, In : Ophthalmology. 125, 5, p. 757-773 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
43 Citations (Scopus)
237 Downloads (Pure)

Interobserver Agreement Among Uveitis Experts on Uveitic Diagnoses: The Standardization of Uveitis Nomenclature Experience

Jabs, D. A., Dick, A., Doucette, J. T., Gupta, A., Lightman, S., McCluskey, P., Okada, A. A., Palestine, A. G., Rosenbaum, J. T., Saleem, S. M., Thorne, J., Trusko, B. & Standardization of Uveitis Nomenclature Working Group, Feb 2018, In : American Journal of Ophthalmology. 186, p. 19-24 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
192 Downloads (Pure)

Outcomes of non-infectious Paediatric uveitis in the era of biologic therapy

Cann, M., Ramanan, A. V., Crawford, A., Dick, A. D., Clarke, S. L. N., Rashed, F. & Guly, C. M., 6 Aug 2018, In : Pediatric Rheumatology. 16, 9 p., 51.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
21 Citations (Scopus)
215 Downloads (Pure)

Reply

Dick, A. D. & Rosenbaum, J. T., Aug 2018, In : Ophthalmology. 125, 8, p. e54

Research output: Contribution to journalComment/debate (Academic Journal)

Re-programming immunosurveillance in persistent non-infectious ocular inflammation

Epps, S. J., Boldison, J., Stimpson, M. L., Khera, T. K., Lait, P. J. P., Copland, D. A., Dick, A. D. & Nicholson, L. B., 1 Jul 2018, In : Progress in Retinal and Eye Research. 65, p. 93-106 14 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
1 Citation (Scopus)
226 Downloads (Pure)

Safety and Efficacy of Adalimumab in Patients with Noninfectious Uveitis in an Ongoing Open-Label Study: VISUAL III

Suhler, E. B., Adán, A., Brézin, A. P., Fortin, E., Goto, H., Jaffe, G. J., Kaburaki, T., Kramer, M., Lim, L. L., Muccioli, C., Nguyen, Q. D., Van Calster, J., Cimino, L., Kron, M., Song, A. P., Liu, J., Pathai, S., Camez, A., Schlaen, A., van Velthoven, M. E. J. & 4 others, Vitale, A. T., Zierhut, M., Tari, S. & Dick, A. D., 1 Jul 2018, In : Ophthalmology. 125, 7, p. 1075-1087 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
41 Citations (Scopus)
264 Downloads (Pure)

Serum vascular endothelial growth factor levels in the IVAN trial; relationships with drug, dosing and systemic serious adverse events: Serum VEGF associations with drug, dosing and systemic SAEs

Rogers, C., Scott, L., Reeves, B., Downes, S., Lotery, A. J., Dick, A., Chakravarthy, U. & IVAN trial investigators, Feb 2018, In : Opthalmology Retina. 2, 2, p. 118-127 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
181 Downloads (Pure)

The Eyes Have It: A Rheumatologist's View of Uveitis

Rosenbaum, J. T. & Dick, A. D., Oct 2018, In : Arthritis and Rheumatology. 70, 10, p. 1533-1543 11 p.

Research output: Contribution to journalReview article (Academic Journal)

Open Access
File
5 Citations (Scopus)
128 Downloads (Pure)

Trial protocol: a multicentre randomised trial of first-line treatment pathways for newly diagnosed immune thrombocytopenia: standard steroid treatment versus combined steroid and mycophenolate. The FLIGHT trial

Pell, J., Greenwood, R. J., Ingram, J. C., Wale, K., Kandiyali, R. S., Mumford, A. D., Dick, A. D., Bagot, C., Cooper, N., Hill, Q. A. & Bradbury, C. A., Oct 2018, In : BMJ Open. 8, 10, 9 p., e024427.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
211 Downloads (Pure)
2017

Adalimumab for uveitis in juvenile idiopathic arthritis

Ramanan, A. V., Dick, A. D. & Beresford, M. W., 24 Aug 2017, In : New England Journal of Medicine. 377, 8, p. 789-790 2 p.

Research output: Contribution to journalComment/debate (Academic Journal)

Open Access
File
5 Citations (Scopus)
223 Downloads (Pure)

Adalimumab plus Methotrexate for Uveitis in Juvenile Idiopathic Arthritis

Ramanan, A. V., Dick, A. D., Jones, A. P., McKay, A., Williamson, P. R., Compeyrot-Lacassagne, S., Hardwick, B., Hickey, H., Hughes, D., Woo, P., Benton, D., Edelsten, C., Beresford, M. W. & SYCAMORE Study Group, 27 Apr 2017, In : New England Journal of Medicine. 376, 17, p. 1637-1646 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
120 Citations (Scopus)
386 Downloads (Pure)