Research output per year
Research output per year
Research output
- 1 - 50 out of 61 results
Search results
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2023
Accurate and interpretable prediction of poor health in small ruminants with accelerometers and machine learning
Montout, A. X., Bhamber, R. S., Lange, D. S., Ndlovu, D. Z., Morgan, E. R., Ioannou, C. C., Terrill, T. H., Wyk, J. A. V., Burghardt, T. & Dowsey, A. W., 21 Apr 2023, (Accepted/In press)Research output: Other contribution
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Five inhibitory receptors display distinct vesicular distributions in T cells
Lu, J., Veler, A., Simonetti, B., Raj, T., Chou, P. H., Cross, S. J., Phillips, A. M., Ruan, X., Huynh, L., Dowsey, A. W., Ye, D., Murphy, R. F., Verkade, P., Cullen, P. J. & Wülfing, C., 22 Jul 2023Research output: Other contribution
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Five inhibitory receptors display distinct vesicular distributions in T cells
Lu, J., Veler, A., Simonetti, B., Raj, T., Chou, P. H., Cross, S. J., Phillips, A. M., Ruan, X., Huynh, L., Dowsey, A. W., Ye, D., Murphy, R. F., Verkade, P., Cullen, P. J. & Wülfing, C., 25 Jul 2023, In: bioRxiv.Research output: Contribution to journal › Article (Academic Journal)
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Prevalence and risk factors for common respiratory pathogens within a cohort of pet cats in the UK
Chan, I., Dowsey, A., Lait, P. J. P., Tasker, S., Blackwell, E-J., Helps, C. R. & Barker, E. N., 29 May 2023, In: Journal of Small Animal Practice. 64, 9, p. 552-560 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
2022
21st century research—One Health, resilience, welfare, and disease
Reyher, K. K., Allen, K., Bailey, M., Dowsey, A., Hezzell, M., Lambton, S., Mann, J., Mendl, M., Peachey, L. & Parkin, T., Aug 2022, In: American Journal of Veterinary Research. 83, 8, p. 1 1 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer's Disease Consistent With Cerebral Pantothenate Deficiency
Sang, C., Philbert, S. A., Hartland, D., Unwin, R. D., Dowsey, A. W., Xu, J. & Cooper, G. J. S., 10 Jun 2022, In: Frontiers in Aging Neuroscience. 14, 13 p., 893159.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile10 Citations (Scopus)7 Downloads (Pure) -
Diagnostic MALDI-TOF MS can differentiate between high and low toxic Staphylococcus aureus bacteraemia isolates as a predictor of patient outcome
Brignoli, T., Recker, M., Lee, W. W. Y., Dong, T., Bhamber, R., Albur, M., Williams, P., Dowsey, A. W. & Massey, R. C., 23 Aug 2022, In: Microbiology. 168, 8, 6 p., 001223.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)18 Downloads (Pure) -
Mast cell infiltration of the choroid and protease release are early events in age-related macular degeneration associated with genetic risk at both chromosomes 1q32 and 10q26
Mcharg, S., Booth, L., Perveen, R., Riba Garcia, I., Brace, N., Bayatti, N., Sergouniotis, P. I., Phillips, A. M., Day, A. J., Black, G. C. M., Clark, S. J., Dowsey, A. W., Unwin, R. D. & Bishop, P. N., 17 May 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 20, p. e2118510119 e2118510119.Research output: Contribution to journal › Article (Academic Journal) › peer-review
4 Citations (Scopus) -
2021
National farm assurance scheme demonstrates welfare outcome improvements for sustainable intensification of dairy production
Mullan, S., Wiltshire, P., Cross, K., Main, D. C. J., Still, K., Crawley, M. & Dowsey, A. W., 11 Aug 2021, (E-pub ahead of print) In: International Journal of Agricultural Sustainability. 18 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile14 Downloads (Pure) -
Taking the steps toward sustainable livestock: our multidisciplinary global farm platform journey
Rivero, M. J., Cartmill, A., Dowsey, A., Farruggia, A., Mignolet, C., Enriquez-Hidalgo, D., McCracken, D. I., Busch, D., Pereyra, F., Brunet, L., Eisler, M. C., Lopez-Villalobos, N., Rovira, P., Suraj, P. T., Puech, T., Boland, T. M., Ayala, W. & Lee, M. R. F., 20 Oct 2021, In: Animal Frontiers. 11, 5, p. 52-58 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile5 Citations (Scopus)12 Downloads (Pure) -
Towards Self-Supervision for Video Identification of Individual Holstein-Friesian Cattle: The Cows2021 Dataset
Gao, J., Burghardt, T., Andrew, W., Dowsey, A. W. & Campbell, N. W., 25 Jun 2021, (Unpublished).Research output: Contribution to conference › Conference Paper › peer-review
File56 Downloads (Pure) -
Uncertainty aware protein-level quantification and differential expression analysis of proteomics data with seaMass
Phillips, A., Unwin, R. D., Hubbard, S. & Dowsey, A., 25 Aug 2021, Statistical Analysis of Proteomic Data. Burger, T. (ed.). Springer, p. 141-162 22 p. (Methods in Molecular Biology; vol. 2426).Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
Open AccessFile1 Citation (Scopus)214 Downloads (Pure) -
Visual identification of individual Holstein-Friesian cattle via deep metric learning
Andrew, W., Gao, J., Mullan, S. M., Campbell, N. W., Dowsey, A. & Burghardt, T., 1 Jun 2021, In: Computers and Electronics in Agriculture. 185, 14 p., 106133.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile32 Citations (Scopus)180 Downloads (Pure) -
What's Stopping Knowledge Synthesis? A Systematic Review of Recent Practices in Research on Smallholder Diversity
Gorman, L., Browne, W. J., Woods, C. J., Eisler, M. C., van Wijk, M. T., Dowsey, A. W. & Hammond, J., 25 Oct 2021, In: Frontiers in Sustainable Food Systems. 5, 727425.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open Access1 Citation (Scopus) -
Widespread severe cerebral elevations of haptoglobin and haemopexin in sporadic Alzheimer's disease: Evidence for a pervasive microvasculopathy
Philbert, S. A., Xu, J., Unwin, R. D., Dowsey, A. W. & Cooper, G. J. S., 28 May 2021, In: Biochemical and Biophysical Research Communications. 555, p. 89-94 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)28 Downloads (Pure) -
2020
mzMLb: a future-proof raw mass spectrometry data format based on standards-compliant mzML and optimized for speed and storage requirements
Bhamber, R. S., Jankevics, A., Deutsch, E. W., Jones, A. R. & Dowsey, A., 29 Oct 2020, In: Journal of Proteome Research. 12 p.Research output: Contribution to journal › Article (Academic Journal)
Open AccessFile11 Citations (Scopus)59 Downloads (Pure) -
2019
Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment: A multidisciplinary investigation
Kassab, S., Begley, P., Church, S. J., Rotariu, S. M., Chevalier-Riffard, C., Dowsey, A. W., Phillips, A. M., Zeef, L. A. H., Grayson, B., Neill, J. C., Cooper, G. J. S., Unwin, R. D. & Gardiner, N. J., 1 Oct 2019, In: Molecular metabolism. 28, p. 107-119 13 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile19 Citations (Scopus)258 Downloads (Pure) -
Patterns of antimicrobial resistance in canine wound infections from two large scale electronic datasets
Holloway, L., Massey, J., Sánchez-Vizcaíno, F., Cogan, T. A., Dowsey, A. & Tivers, M., Apr 2019, BSAVA Congress Proceedings 2019. 1 ed. Birmingham, UK: British Small Animal Veterinary Association, p. 445-446Research output: Chapter in Book/Report/Conference proceeding › Conference Contribution (Conference Proceeding)
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Regional protein expression in human Alzheimer's brain correlates with disease severity
Xu, J., Patassini, S., Rustogi, N., Riba-Garcia, I., Hale, B. D., Phillips, A. M., Waldvogel, H., Haines, R., Bradbury, P., Stevens, A., Faull, R. L. M., Dowsey, A. W., Cooper, G. J. S. & Unwin, R. D., 4 Feb 2019, In: Communications Biology. 2, 15 p., 43 (2019).Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile105 Citations (Scopus)215 Downloads (Pure) -
2018
Ceasing the use of the highest priority critically important antimicrobials does not adversely affect production, health or welfare parameters in dairy cows
Turner, A., Tisdall, D., Barrett, D. C., Wood, S., Dowsey, A. & Reyher, K. K., 12 Jul 2018, In: Veterinary Record. 183, 2, 1 p., 67.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile21 Citations (Scopus)370 Downloads (Pure) -
Evaluation of metrics for benchmarking antimicrobial use in the UK dairy industry
Mills, H. L., Turner, A., Morgans, L., Massey, J., Schubert, H., Rees, G., Barrett, D., Dowsey, A. & Reyher, K. K., 31 Mar 2018, In: Veterinary Record. 182, 13, 10 p.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open AccessFile40 Citations (Scopus)449 Downloads (Pure) -
Expanding the Use of Spectral Libraries in Proteomics
Deutsch, E. W., Perez-Riverol, Y., Chalkley, R. J., Wilhelm, M., Tate, S., Sachsenberg, T., Walzer, M., Käll, L., Delanghe, B., Böcker, S., Schymanski, E. L., Wilmes, P., Dorfer, V., Kuster, B., Volders, P. J., Jehmlich, N., Vissers, J. P. C., Wolan, D. W., Wang, A. Y., Mendoza, L., & 10 others, 7 Dec 2018, In: Journal of Proteome Research. 17, 12, p. 4051-4060 10 p.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
39 Citations (Scopus) -
2017
Algorithms for MS1-Based Quantitation
Liao, H., Phillips, A., Jankevics, A. & Dowsey, A. W., 2017, Proteome Informatics. 5 ed. Royal Society of Chemistry, Vol. 2017-January. p. 135-154 20 p. (New Developments in Mass Spectrometry; vol. 2017-January, no. 5).Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
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Evaluation of Metrics for Benchmarking Antimicrobial Use in the United Kingdom Dairy Industry
Mills, H., Turner, A., Morgans, L., Massey, J., Schubert, H., Rees, G., Broadfoot, F., Barrett, D. C., Dowsey, A. & Reyher, K. K., Sept 2017Research output: Other contribution
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Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice
Aitken, J. F., Loomes, K. M., Riba-Garcia, I., Unwin, R. D., Prijic, G., Phillips, A. S., Phillips, A. R. J., Wu, D., Poppitt, S. D., Ding, K., Barran, P. E., Dowsey, A. W. & Cooper, G. J. S., Feb 2017, In: Data in Brief. 10, p. 298-303 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile2 Citations (Scopus)313 Downloads (Pure) -
Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice
Aitken, J. F., Loomes, K. M., Riba-Garcia, I., Unwin, R. D., Prijic, G., Phillips, A. S., Phillips, A. R. J., Wu, D., Poppitt, S. D., Ding, K., Barran, P. E., Dowsey, A. W. & Cooper, G. J. S., 22 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 4, p. 625–631 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile26 Citations (Scopus)389 Downloads (Pure) -
The need for statistical contributions to bioinformatics at scale, with illustration to mass spectrometry
Dowsey, A. W., 1 Aug 2017, In: Statistical Modelling. 17, 4-5, p. 290-299 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile355 Downloads (Pure) -
2016
Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: Metabolic basis for dementia
Xu, J., Begley, P., Church, S. J., Patassini, S., McHarg, S., Kureishy, N., Hollywood, K. A., Waldvogel, H. J., Liu, H., Zhang, S., Lin, W., Herholz, K., Turner, C., Synek, B. J., Curtis, M. A., Rivers-Auty, J., Lawrence, C. B., Kellett, K. A. B., Hooper, N. M., Vardy, E. R. L. C., & 5 others, 9 Jun 2016, In: Scientific Reports. 6, 12 p., 27524.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile59 Citations (Scopus)311 Downloads (Pure) -
Metabolic dysfunction is restricted to the sciatic nerve in experimental diabetic neuropathy
Freeman, O. J., Unwin, R. D., Dowsey, A. W., Begley, P., Ali, S., Hollywood, K. A., Rustogi, N., Petersen, R. S., Dunn, W. B., Cooper, G. J. S. & Gardiner, N. J., Jan 2016, In: Diabetes. 65, 1, p. 228-238 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
71 Citations (Scopus) -
2015
Boosting drug named entity recognition using an aggregate classifier
Korkontzelos, I., Piliouras, D., Dowsey, A. W. & Ananiadou, S., 1 Oct 2015, In: Artificial Intelligence in Medicine. 65, 2, p. 145-153 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
36 Citations (Scopus) -
Streaming visualisation of quantitative mass spectrometry data based on a novel raw signal decomposition method
Zhang, Y., Bhamber, R. S., Riba-Garcia, I., Liao, H., Unwin, R. D. & Dowsey, A. W., 1 Apr 2015, In: Proteomics. 15, 8, p. 1419-1427 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
6 Citations (Scopus) -
Understanding the placental mechanisms underpinning increased fetal growth in a mouse model of FGR following sildenafil citrate treatment: Insight from network analyses
Stevens, A., Unwin, R., Rustogi, N., Dowsey, A., Cooper, G., Greenwood, S., Wareing, M., Baker, P., Sibley, C., Westwood, M. & Dilworth, M., Sept 2015, In: Placenta.Research output: Contribution to journal › Article (Academic Journal)
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2014
Age-dependent changes in heparan sulfate in human Bruch's membrane: Implications for age-related macular degeneration
Keenan, T. D. L., Pickford, C. E., Holley, R. J., Clark, S. J., Lin, W., Dowsey, A. W., Merry, C. L., Day, A. J. & Bishop, P. N., 29 Jul 2014, In: Investigative Ophthalmology and Visual Science. 55, 8, p. 5370-5379 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
52 Citations (Scopus) -
A new paradigm for clinical biomarker discovery and screening with mass spectrometry through biomedical image analysis principles
Liao, H., Moschidis, E., Riba-Garcia, I., Zhang, Y., Unwin, R. D., Morris, J. S., Graham, J. & Dowsey, A. W., 29 Jul 2014, 2014 IEEE 11th International Symposium on Biomedical Imaging, ISBI 2014. Institute of Electrical and Electronics Engineers (IEEE), p. 1332-1335 4 p. 6868123Research output: Chapter in Book/Report/Conference proceeding › Conference Contribution (Conference Proceeding)
6 Citations (Scopus) -
Network analysis: a new approach to study endocrine disorders
Stevens, A., De Leonibus, C., Hanson, D., Dowsey, A. W., Whatmore, A., Meyer, S., Donn, R. P., Chatelain, P., Banerjee, I., Cosgrove, K. E., Clayton, P. E. & Dunne, M. J., Feb 2014, In: Journal of Molecular Endocrinology. 52, 1, p. R79-93Research output: Contribution to journal › Article (Academic Journal) › peer-review
27 Citations (Scopus) -
Numerical compression schemes for proteomics mass spectrometry data
Teleman, J., Dowsey, A. W., Gonzalez-Galarza, F. F., Perkins, S., Pratt, B., Röst, H. L., Malmström, L., Malmström, J., Jones, A. R., Deutsch, E. W. & Levander, F., 2014, In: Molecular and Cellular Proteomics. 13, 6, p. 1537-1542 6 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
43 Citations (Scopus) -
2013
Dealing with data sparsity in drug named entity recognition
Piliouras, D., Korkontzelos, I., Dowsey, A. & Ananiadou, S., 2013, Proceedings - 2013 IEEE International Conference on Healthcare Informatics, ICHI 2013. p. 14-21 8 p. 6680456Research output: Chapter in Book/Report/Conference proceeding › Conference Contribution (Conference Proceeding)
2 Citations (Scopus) -
2011
Cardiovascular magnetic resonance tagging of the right ventricular free wall for the assessment of long axis myocardial function in congenital heart disease
Chen, S. S. M., Keegan, J., Dowsey, A. W., Ismail, T., Wage, R., Li, W., Yang, G. Z., Firmin, D. N. & Kilner, P. J., 2011, In: Journal of Cardiovascular Magnetic Resonance. 13, 1, 80.Research output: Contribution to journal › Article (Academic Journal) › peer-review
19 Citations (Scopus) -
Image analysis tools in proteomics
Dowsey, A., English, J. A., Lisacek, F., Morris, J. S., Yang, G. Z. & Dunn, M. J., 2011, Encyclopedia of Life Sciences. Chichester: John Wiley & Sons, IncResearch output: Chapter in Book/Report/Conference proceeding › Chapter in a book
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2010
Guidelines for reporting the use of gel image informatics in proteomics
Hoogland, C., O'Gorman, M., Bogard, P., Gibson, F., Berth, M., Cockell, S. J., Ekefjärd, A., Forsstrom-Olsson, O., Kapferer, A., Nilsson, M., Martínez-Bartolomé, S., Albar, J. P., Echevarría-Zomẽo, S., Martínez-Gomariz, M., Joets, J., Binz, P. A., Taylor, C. F., Dowsey, A. & Jones, A. R., 2010, In: Nature Biotechnology. 28, 7, p. 655-656 2 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
20 Citations (Scopus) -
Image analysis tools and emerging algorithms for expression proteomics
Dowsey, A. W., English, J. A., Lisacek, F., Morris, J. S., Yang, G. Z. & Dunn, M. J., Dec 2010, In: Proteomics. 10, 23, p. 4226-4257 32 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
44 Citations (Scopus) -
Informatics and Statistics for Analyzing 2-D Gel Electrophoresis Images
Dowsey, A., Morris, J. S., Yang, G. Z. & Dunn, M. J., 2010, Proteome Bioinformatics. Hubbard, S. J. & Jones, A. R. (eds.). New York: Springer, p. 239-255 17 p. (Methods in Molecular Biology™; vol. 604).Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book
16 Citations (Scopus) -
MR image-based geometric and hemodynamic investigation of the right coronary artery with dynamic vessel motion
Torii, R., Keegan, J., Wood, N. B., Dowsey, A. W., Hughes, A. D., Yang, G. Z., Firmin, D. N., Thom, S. A. M. & Xu, X. Y., Aug 2010, In: Annals of Biomedical Engineering. 38, 8, p. 2606-2620 15 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
34 Citations (Scopus) -
2009
CMR tagging for measurement of the long axis function and deformation rate of the systemic right ventricular free wall
Chen, S. SM., Keegan, J., Dowsey, A. W., Wage, R., Firmin, D. N. & Kilner, P. J., 2009, In: Journal of Cardiovascular Magnetic Resonance.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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Fluid-structure interaction analysis of a patient-specific right coronary artery with physiological velocity and pressure waveforms
Torii, R., Wood, N. B., Hadjiloizou, N., Dowsey, A. W., Wright, A. R., Hughes, A. D., Davies, J., Francis, D. P., Mayet, J., Yang, G. Z., Thom, S. A. M. & Xu, X. Y., 2009, In: Communications in Numerical Methods in Engineering. 25, 5, p. 565-580 16 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
123 Citations (Scopus) -
Stress phase angle depicts differences in coronary artery hemodynamics due to changes in flow and geometry after percutaneous coronary intervention
Torii, R., Wood, N. B., Hadjiloizou, N., Dowsey, A. W., Wright, A. R., Hughes, A. D., Davies, J., Francis, D. P., Mayet, J., Yang, G. Z., Thom, S. A. M. & Xu, X. Y., Mar 2009, In: AJP - Heart and Circulatory Physiology. 296, 3, p. H765-H776Research output: Contribution to journal › Article (Academic Journal) › peer-review
29 Citations (Scopus) -
The effect of dynamic vessel motion on haemodynamic parameters in the right coronary artery: A combined MR and CFD study
Torii, R., Keegan, J., Wood, N. B., Dowsey, A. W., Hughes, A. D., Yang, G. Z., Firmin, D. N., McG Thom, S. A. & Xu, X. Y., 1 Jan 2009, In: British Journal of Radiology. 82, SPEC. ISSUE 1Research output: Contribution to journal › Article (Academic Journal) › peer-review
26 Citations (Scopus) -
2008
A CFD study on coronary artery haemodynamics with dynamic vessel motion based on MR images
Torii, R., Keegan, J., Dowsey, A., Wood, N., Yang, G-Z., Firmin, D., Hughes, A., Thom, S. & Xu, X. Y., Jul 2008, In: Journal of Biomechanics.Research output: Contribution to journal › Article (Academic Journal)
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Automated image alignment for 2D gel electrophoresis in a high-throughput proteomics pipeline
Dowsey, A. W., Dunn, M. J. & Yang, G. Z., Apr 2008, In: Bioinformatics. 24, 7, p. 950-957 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
32 Citations (Scopus) -
The future of large-scale collaborative proteomics
Dowsey, A. W. & Yang, G. Z., Aug 2008, In: Proceedings of the IEEE. 96, 8, p. 1292-1309 18 p., 4567693.Research output: Contribution to journal › Article (Academic Journal) › peer-review
3 Citations (Scopus)