Andrew Dowsey

2024

A Bayesian Model Based on Local Phenotypic Resistance Data to Inform Empiric Antibiotic Escalation Decisions

Bamber, R., Sullivan, B., Gorman, L., Lee, W. W. Y., Avison, M. B., Dowsey, A. W. & Williams, P. B., 18 Jul 2024, (E-pub ahead of print) In: Infectious diseases and therapy. 13, 9, p. 1963-1981 19 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

Epidemiology of Escherichia coli bloodstream infection antimicrobial resistance trends across South West England during the first 2 years of the coronavirus disease 2019 pandemic response

Stanley, J., Sullivan, B., Dowsey, A. W., Jones, K. & Beck, C. R., 23 Mar 2024, (E-pub ahead of print) In: Clinical Microbiology and Infection. 30, 10, p. 1291-1297 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

Novel characterisation of sheep flocks in Wales: A description of principal flock typologies and antimicrobial use patterns

Best, C. M., Vass, L., Stanton, E., Bettridge, J., Dowsey, A. W. & Reyher, K. K., 1 Dec 2024, In: Preventive Veterinary Medicine. 233, p. 1-15 15 p., 106352.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Universal bovine identification via depth data and deep metric learning

Sharma, A., Randewich, L., Andrew, W., Hannuna, S., Campbell, N., Mullan, S., Dowsey, A. W., Smith, M., Hansen, M. & Burghardt, T., 1 Feb 2025, In: Computers and Electronics in Agriculture. 229, 16 p., 109657.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

59 Downloads (Pure)

2023

Better understanding the associations between antimicrobial use and resistance through active surveillance of AMR on cattle and sheep farms across Wales

Best, C. M., Vass, L., Mounsey, O., Sealey, K., Llamazares, B., Moiseienko, Y., Miller, W., Bettridge, J. M., Sealey, J. E., Dowsey, A. W., Avison, M. B. & Reyher, K. K., Oct 2023, In: Cattle Practice. 31, p. 24-25 2 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells

Lu, J., Veler, A., Simonetti, B., Raj, T., Chou, P. H., Cross, S. J., Phillips, A. M., Ruan, X., Huynh, L., Dowsey, A. W., Ye, D., Murphy, R. F., Verkade, P., Cullen, P. J. & Wülfing, C., 31 Oct 2023, In: Cells. 12, 21, 32 p., 2558.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

1 Citation (Scopus)

12 Downloads (Pure)

Prevalence and risk factors for common respiratory pathogens within a cohort of pet cats in the UK

Chan, I., Dowsey , A., Lait, P. J. P., Tasker, S., Blackwell, E.-J., Helps , C. R. & Barker, E. N., 10 Sept 2023, In: Journal of Small Animal Practice. 64, 9, p. 552-560 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

5 Citations (Scopus)

2022

21st century research—One Health, resilience, welfare, and disease

Reyher, K. K., Allen, K., Bailey, M., Dowsey, A., Hezzell, M., Lambton, S., Mann, J., Mendl, M., Peachey, L. & Parkin, T., Aug 2022, In: American Journal of Veterinary Research. 83, 8, p. 1 1 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Coenzyme A-Dependent Tricarboxylic Acid Cycle Enzymes Are Decreased in Alzheimer's Disease Consistent With Cerebral Pantothenate Deficiency

Sang, C., Philbert, S. A., Hartland, D., Unwin, R. D., Dowsey, A. W., Xu, J. & Cooper, G. J. S., 10 Jun 2022, In: Frontiers in Aging Neuroscience. 14, 13 p., 893159.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

18 Citations (Scopus)

48 Downloads (Pure)

Diagnostic MALDI-TOF MS can differentiate between high and low toxic Staphylococcus aureus bacteraemia isolates as a predictor of patient outcome

Brignoli, T., Recker, M., Lee, W. W. Y., Dong, T., Bhamber, R., Albur, M., Williams, P., Dowsey, A. W. & Massey, R. C., 23 Aug 2022, In: Microbiology. 168, 8, 6 p., 001223.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

1 Citation (Scopus)

96 Downloads (Pure)

Mast cell infiltration of the choroid and protease release are early events in age-related macular degeneration associated with genetic risk at both chromosomes 1q32 and 10q26

Mcharg, S., Booth, L., Perveen, R., Riba Garcia, I., Brace, N., Bayatti, N., Sergouniotis, P. I., Phillips, A. M., Day, A. J., Black, G. C. M., Clark, S. J., Dowsey, A. W., Unwin, R. D. & Bishop, P. N., 17 May 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 20, p. e2118510119 e2118510119.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

13 Citations (Scopus)

2021

National farm assurance scheme demonstrates welfare outcome improvements for sustainable intensification of dairy production

Mullan, S., Wiltshire, P., Cross, K., Main, D. C. J., Still, K., Crawley, M. & Dowsey , A. W., 11 Aug 2021, (E-pub ahead of print) In: International Journal of Agricultural Sustainability. 18 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

2 Citations (Scopus)

66 Downloads (Pure)

Taking the steps toward sustainable livestock: our multidisciplinary global farm platform journey

Rivero, M. J., Cartmill, A., Dowsey, A., Farruggia, A., Mignolet, C., Enriquez-Hidalgo, D., McCracken, D. I., Busch, D., Pereyra, F., Brunet, L., Eisler, M. C., Lopez-Villalobos, N., Rovira, P., Suraj, P. T., Puech, T., Boland, T. M., Ayala, W. & Lee, M. R. F., 20 Oct 2021, In: Animal Frontiers. 11, 5, p. 52-58 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

10 Citations (Scopus)

43 Downloads (Pure)

Visual identification of individual Holstein-Friesian cattle via deep metric learning

Andrew, W., Gao, J., Mullan, S. M., Campbell, N. W., Dowsey , A. & Burghardt, T., 1 Jun 2021, In: Computers and Electronics in Agriculture. 185, 14 p., 106133.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

84 Citations (Scopus)

438 Downloads (Pure)

Widespread severe cerebral elevations of haptoglobin and haemopexin in sporadic Alzheimer's disease: Evidence for a pervasive microvasculopathy

Philbert, S. A., Xu, J., Unwin, R. D., Dowsey, A. W. & Cooper, G. J. S., 28 May 2021, In: Biochemical and Biophysical Research Communications. 555, p. 89-94 6 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

8 Citations (Scopus)

123 Downloads (Pure)

2020

mzMLb: a future-proof raw mass spectrometry data format based on standards-compliant mzML and optimized for speed and storage requirements

Bhamber, R. S., Jankevics, A., Deutsch, E. W., Jones, A. R. & Dowsey, A., 29 Oct 2020, In: Journal of Proteome Research. 12 p.

Research output: Contribution to journal › Article (Academic Journal)

Open Access

File

15 Citations (Scopus)

119 Downloads (Pure)

2019

Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment: A multidisciplinary investigation

Kassab, S., Begley, P., Church, S. J., Rotariu, S. M., Chevalier-Riffard, C., Dowsey, A. W., Phillips, A. M., Zeef, L. A. H., Grayson, B., Neill, J. C., Cooper, G. J. S., Unwin, R. D. & Gardiner, N. J., 1 Oct 2019, In: Molecular metabolism. 28, p. 107-119 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

21 Citations (Scopus)

345 Downloads (Pure)

Regional protein expression in human Alzheimer's brain correlates with disease severity

Xu, J., Patassini, S., Rustogi, N., Riba-Garcia, I., Hale, B. D., Phillips, A. M., Waldvogel, H., Haines, R., Bradbury, P., Stevens, A., Faull, R. L. M., Dowsey, A. W., Cooper, G. J. S. & Unwin, R. D., 4 Feb 2019, In: Communications Biology. 2, 15 p., 43 (2019).

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

121 Citations (Scopus)

271 Downloads (Pure)

2018

Ceasing the use of the highest priority critically important antimicrobials does not adversely affect production, health or welfare parameters in dairy cows

Turner, A., Tisdall, D., Barrett, D. C., Wood, S., Dowsey, A. & Reyher, K. K., 12 Jul 2018, In: Veterinary Record. 183, 2, 1 p., 67.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

24 Citations (Scopus)

415 Downloads (Pure)

2017

Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice

Aitken, J. F., Loomes, K. M., Riba-Garcia, I., Unwin, R. D., Prijic, G., Phillips, A. S., Phillips, A. R. J., Wu, D., Poppitt, S. D., Ding, K., Barran, P. E., Dowsey, A. W. & Cooper, G. J. S., Feb 2017, In: Data in Brief. 10, p. 298-303 6 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

2 Citations (Scopus)

1504 Downloads (Pure)

Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice

Aitken, J. F., Loomes, K. M., Riba-Garcia, I., Unwin, R. D., Prijic, G., Phillips, A. S., Phillips, A. R. J., Wu, D., Poppitt, S. D., Ding, K., Barran, P. E., Dowsey, A. W. & Cooper, G. J. S., 22 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 4, p. 625–631 7 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

28 Citations (Scopus)

469 Downloads (Pure)

The need for statistical contributions to bioinformatics at scale, with illustration to mass spectrometry

Dowsey, A. W., 1 Aug 2017, In: Statistical Modelling. 17, 4-5, p. 290-299 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

401 Downloads (Pure)

2016

Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: Metabolic basis for dementia

Xu, J., Begley, P., Church, S. J., Patassini, S., McHarg, S., Kureishy, N., Hollywood, K. A., Waldvogel, H. J., Liu, H., Zhang, S., Lin, W., Herholz, K., Turner, C., Synek, B. J., Curtis, M. A., Rivers-Auty, J., Lawrence, C. B., Kellett, K. A. B., Hooper, N. M. & Vardy, E. R. L. C. & 5 others, Wu, D., Unwin, R. D., Faull, R. L. M., Cooper, G. J. S. & Dowsey, A., 9 Jun 2016, In: Scientific Reports. 6, 12 p., 27524.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

69 Citations (Scopus)

352 Downloads (Pure)

Metabolic dysfunction is restricted to the sciatic nerve in experimental diabetic neuropathy

Freeman, O. J., Unwin, R. D., Dowsey, A. W., Begley, P., Ali, S., Hollywood, K. A., Rustogi, N., Petersen, R. S., Dunn, W. B., Cooper, G. J. S. & Gardiner, N. J., Jan 2016, In: Diabetes. 65, 1, p. 228-238 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

77 Citations (Scopus)

2015

Boosting drug named entity recognition using an aggregate classifier

Korkontzelos, I., Piliouras, D., Dowsey, A. W. & Ananiadou, S., 1 Oct 2015, In: Artificial Intelligence in Medicine. 65, 2, p. 145-153 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

41 Citations (Scopus)

Streaming visualisation of quantitative mass spectrometry data based on a novel raw signal decomposition method

Zhang, Y., Bhamber, R. S., Riba-Garcia, I., Liao, H., Unwin, R. D. & Dowsey, A. W., 1 Apr 2015, In: Proteomics. 15, 8, p. 1419-1427 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

6 Citations (Scopus)

Understanding the placental mechanisms underpinning increased fetal growth in a mouse model of FGR following sildenafil citrate treatment: Insight from network analyses

Stevens, A., Unwin, R., Rustogi, N., Dowsey, A., Cooper, G., Greenwood, S., Wareing, M., Baker, P., Sibley, C., Westwood, M. & Dilworth, M., 25 Aug 2015, In: Placenta. 36, 9, p. A9-A10

Research output: Contribution to journal › Article (Academic Journal)

2014

Age-dependent changes in heparan sulfate in human Bruch's membrane: Implications for age-related macular degeneration

Keenan, T. D. L., Pickford, C. E., Holley, R. J., Clark, S. J., Lin, W., Dowsey, A. W., Merry, C. L., Day, A. J. & Bishop, P. N., 29 Jul 2014, In: Investigative Ophthalmology and Visual Science. 55, 8, p. 5370-5379 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

57 Citations (Scopus)

Network analysis: a new approach to study endocrine disorders

Stevens, A., De Leonibus, C., Hanson, D., Dowsey, A. W., Whatmore, A., Meyer, S., Donn, R. P., Chatelain, P., Banerjee, I., Cosgrove, K. E., Clayton, P. E. & Dunne, M. J., Feb 2014, In: Journal of Molecular Endocrinology. 52, 1, p. R79-93

Research output: Contribution to journal › Article (Academic Journal) › peer-review

28 Citations (Scopus)

Numerical compression schemes for proteomics mass spectrometry data

Teleman, J., Dowsey, A. W., Gonzalez-Galarza, F. F., Perkins, S., Pratt, B., Röst, H. L., Malmström, L., Malmström, J., Jones, A. R., Deutsch, E. W. & Levander, F., 2014, In: Molecular and Cellular Proteomics. 13, 6, p. 1537-1542 6 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

48 Citations (Scopus)

2011

Cardiovascular magnetic resonance tagging of the right ventricular free wall for the assessment of long axis myocardial function in congenital heart disease

Chen, S. S. M., Keegan, J., Dowsey, A. W., Ismail, T., Wage, R., Li, W., Yang, G. Z., Firmin, D. N. & Kilner, P. J., 2011, In: Journal of Cardiovascular Magnetic Resonance. 13, 1, 80.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

20 Citations (Scopus)

2010

Guidelines for reporting the use of gel image informatics in proteomics

Hoogland, C., O'Gorman, M., Bogard, P., Gibson, F., Berth, M., Cockell, S. J., Ekefjärd, A., Forsstrom-Olsson, O., Kapferer, A., Nilsson, M., Martínez-Bartolomé, S., Albar, J. P., Echevarría-Zomẽo, S., Martínez-Gomariz, M., Joets, J., Binz, P. A., Taylor, C. F., Dowsey, A. & Jones, A. R., 2010, In: Nature Biotechnology. 28, 7, p. 655-656 2 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

20 Citations (Scopus)

Image analysis tools and emerging algorithms for expression proteomics

Dowsey, A. W., English, J. A., Lisacek, F., Morris, J. S., Yang, G. Z. & Dunn, M. J., Dec 2010, In: Proteomics. 10, 23, p. 4226-4257 32 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

44 Citations (Scopus)

MR image-based geometric and hemodynamic investigation of the right coronary artery with dynamic vessel motion

Torii, R., Keegan, J., Wood, N. B., Dowsey, A. W., Hughes, A. D., Yang, G. Z., Firmin, D. N., Thom, S. A. M. & Xu, X. Y., Aug 2010, In: Annals of Biomedical Engineering. 38, 8, p. 2606-2620 15 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

42 Citations (Scopus)

2009

CMR tagging for measurement of the long axis function and deformation rate of the systemic right ventricular free wall

Chen, S. S., Keegan, J., Dowsey, A. W., Wage, R., Firmin, D. N. & Kilner, P. J., 2009, In: Journal of Cardiovascular Magnetic Resonance.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Fluid-structure interaction analysis of a patient-specific right coronary artery with physiological velocity and pressure waveforms

Torii, R., Wood, N. B., Hadjiloizou, N., Dowsey, A. W., Wright, A. R., Hughes, A. D., Davies, J., Francis, D. P., Mayet, J., Yang, G. Z., Thom, S. A. M. & Xu, X. Y., 2009, In: Communications in Numerical Methods in Engineering. 25, 5, p. 565-580 16 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

136 Citations (Scopus)

Stress phase angle depicts differences in coronary artery hemodynamics due to changes in flow and geometry after percutaneous coronary intervention

Torii, R., Wood, N. B., Hadjiloizou, N., Dowsey, A. W., Wright, A. R., Hughes, A. D., Davies, J., Francis, D. P., Mayet, J., Yang, G. Z., Thom, S. A. M. & Xu, X. Y., Mar 2009, In: AJP - Heart and Circulatory Physiology. 296, 3, p. H765-H776

Research output: Contribution to journal › Article (Academic Journal) › peer-review

30 Citations (Scopus)

The effect of dynamic vessel motion on haemodynamic parameters in the right coronary artery: A combined MR and CFD study

Torii, R., Keegan, J., Wood, N. B., Dowsey, A. W., Hughes, A. D., Yang, G. Z., Firmin, D. N., McG Thom, S. A. & Xu, X. Y., 1 Jan 2009, In: British Journal of Radiology. 82, SPEC. ISSUE 1

Research output: Contribution to journal › Article (Academic Journal) › peer-review

29 Citations (Scopus)

2008

A CFD study on coronary artery haemodynamics with dynamic vessel motion based on MR images

Torii, R., Keegan, J., Dowsey, A., Wood, N., Yang, G.-Z., Firmin, D., Hughes, A., Thom, S. & Xu, X. Y., 1 Jul 2008, In: Journal of Biomechanics. 41, Supplement 1, p. S212 1 p.

Research output: Contribution to journal › Article (Academic Journal)

Automated image alignment for 2D gel electrophoresis in a high-throughput proteomics pipeline

Dowsey, A. W., Dunn, M. J. & Yang, G. Z., Apr 2008, In: Bioinformatics. 24, 7, p. 950-957 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

33 Citations (Scopus)

The future of large-scale collaborative proteomics

Dowsey, A. W. & Yang, G. Z., Aug 2008, In: Proceedings of the IEEE. 96, 8, p. 1292-1309 18 p., 4567693.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

3 Citations (Scopus)

2006

Adaptive cardiovascular imaging: Challenges and opportunities for real-time processing

Dowsey, A. W., Merrifield, R. D. & Yang, G. Z., Sept 2006, In: IEEE Signal Processing Magazine. 23, 5, p. 112-116 5 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

2 Citations (Scopus)

Examination of 2-DE in the Human Proteome Organisation Brain Proteome Project pilot studies with the new RAIN gel matching technique

Dowsey, A. W., English, J., Pennington, K., Cotter, D., Stuehler, K., Marcus, K., Meyer, H. E., Dunn, M. J. & Yang, G. Z., Sept 2006, In: Proteomics. 6, 18, p. 5030-5047 18 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

25 Citations (Scopus)

The HUPO Brain Proteome Project Jamboree: Centralised summary of the pilot studies

Hamacher, M., Stephan, C., Blüggel, M., Chamrad, D., Körting, G., Martens, L., Müller, M., Hermjakob, H., Parkinson, D., Dowsey, A., Reidegeld, K. A., Marcus, K., Dunn, M. J., Meyer, H. E. & Apweiler, R., Mar 2006, In: Proteomics. 6, 6, p. 1719-1721 3 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

2 Citations (Scopus)

2005

The road to high-throughput proteomics

Dowsey, A. & Yang, G. Z., Sept 2005, In: EBR - European Biopharmaceutical Review. AUTUMN, p. 30-34 5 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

2004

ProteomeGRID: Towards a high-throughput proteomics pipeline through opportunistic cluster image computing for two-dimensional gel electrophoresis

Dowsey, A. W., Dunn, M. J. & Yang, G. Z., Dec 2004, In: Proteomics. 4, 12, p. 3800-3812 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

15 Citations (Scopus)

2003

The role of bioinformatics in two-dimensional gel electrophoresis

Dowsey, A. W., Dunn, M. J. & Yang, G. Z., 1 Aug 2003, In: Proteomics. 3, 8, p. 1567-1596 30 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

161 Citations (Scopus)

Professor Andrew Dowsey

Research output

Search results