Professor Andrew Dowsey

MEng(Lond.), PhD

  • BS40 5DU

  • BS40 5DU

    United Kingdom

20032020

Research output per year

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Research Output

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Article (Academic Journal)
2020

mzMLb: a future-proof raw mass spectrometry data format based on standards-compliant mzML and optimized for speed and storage requirements

Bhamber, R. S., Jankevics, A., Deutsch, E. W., Jones, A. R. & Dowsey, A., 24 Mar 2020, (Unpublished) In : bioRxiv. 32 p.

Research output: Contribution to journalArticle (Academic Journal)

File
44 Downloads (Pure)

Visual Identification of Individual Holstein-Friesian Cattle via Deep Metric Learning

Andrew, W., Gao, J., Mullan, S. M., Campbell, N. W., Dowsey, A. & Burghardt, T., 16 Jun 2020, (Unpublished) In : arXiv. 37 p.

Research output: Contribution to journalArticle (Academic Journal)

File
3 Downloads (Pure)
2019

Cognitive dysfunction in diabetic rats is prevented by pyridoxamine treatment: A multidisciplinary investigation

Kassab, S., Begley, P., Church, S. J., Rotariu, S. M., Chevalier-Riffard, C., Dowsey, A. W., Phillips, A. M., Zeef, L. A. H., Grayson, B., Neill, J. C., Cooper, G. J. S., Unwin, R. D. & Gardiner, N. J., 1 Oct 2019, In : Molecular metabolism. 28, p. 107-119 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
155 Downloads (Pure)

Regional protein expression in human Alzheimer's brain correlates with disease severity

Xu, J., Patassini, S., Rustogi, N., Riba-Garcia, I., Hale, B. D., Phillips, A. M., Waldvogel, H., Haines, R., Bradbury, P., Stevens, A., Faull, R. L. M., Dowsey, A. W., Cooper, G. J. S. & Unwin, R. D., 4 Feb 2019, In : Communications Biology. 2, 15 p., 43 (2019).

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
153 Downloads (Pure)
2018
Open Access
File
8 Citations (Scopus)
307 Downloads (Pure)
2017

Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice

Aitken, J. F., Loomes, K. M., Riba-Garcia, I., Unwin, R. D., Prijic, G., Phillips, A. S., Phillips, A. R. J., Wu, D., Poppitt, S. D., Ding, K., Barran, P. E., Dowsey, A. W. & Cooper, G. J. S., Feb 2017, In : Data in Brief. 10, p. 298-303 6 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
276 Downloads (Pure)

Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice

Aitken, J. F., Loomes, K. M., Riba-Garcia, I., Unwin, R. D., Prijic, G., Phillips, A. S., Phillips, A. R. J., Wu, D., Poppitt, S. D., Ding, K., Barran, P. E., Dowsey, A. W. & Cooper, G. J. S., 22 Jan 2017, In : Biochemical and Biophysical Research Communications. 482, 4, p. 625–631 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
282 Downloads (Pure)

The need for statistical contributions to bioinformatics at scale, with illustration to mass spectrometry

Dowsey, A. W., 1 Aug 2017, In : Statistical Modelling. 17, 4-5, p. 290-299 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
233 Downloads (Pure)
2016

Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer's disease: Metabolic basis for dementia

Xu, J., Begley, P., Church, S. J., Patassini, S., McHarg, S., Kureishy, N., Hollywood, K. A., Waldvogel, H. J., Liu, H., Zhang, S., Lin, W., Herholz, K., Turner, C., Synek, B. J., Curtis, M. A., Rivers-Auty, J., Lawrence, C. B., Kellett, K. A. B., Hooper, N. M., Vardy, E. R. L. C. & 5 others, Wu, D., Unwin, R. D., Faull, R. L. M., Cooper, G. J. S. & Dowsey, A., 9 Jun 2016, In : Scientific Reports. 6, 12 p., 27524.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
30 Citations (Scopus)
293 Downloads (Pure)

Metabolic dysfunction is restricted to the sciatic nerve in experimental diabetic neuropathy

Freeman, O. J., Unwin, R. D., Dowsey, A. W., Begley, P., Ali, S., Hollywood, K. A., Rustogi, N., Petersen, R. S., Dunn, W. B., Cooper, G. J. S. & Gardiner, N. J., Jan 2016, In : Diabetes. 65, 1, p. 228-238 11 p.

Research output: Contribution to journalArticle (Academic Journal)

43 Citations (Scopus)
2015

Boosting drug named entity recognition using an aggregate classifier

Korkontzelos, I., Piliouras, D., Dowsey, A. W. & Ananiadou, S., 1 Oct 2015, In : Artificial Intelligence in Medicine. 65, 2, p. 145-153 9 p.

Research output: Contribution to journalArticle (Academic Journal)

25 Citations (Scopus)

Streaming visualisation of quantitative mass spectrometry data based on a novel raw signal decomposition method

Zhang, Y., Bhamber, R. S., Riba-Garcia, I., Liao, H., Unwin, R. D. & Dowsey, A. W., 1 Apr 2015, In : Proteomics. 15, 8, p. 1419-1427 9 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)
2014

Age-dependent changes in heparan sulfate in human Bruch's membrane: Implications for age-related macular degeneration

Keenan, T. D. L., Pickford, C. E., Holley, R. J., Clark, S. J., Lin, W., Dowsey, A. W., Merry, C. L., Day, A. J. & Bishop, P. N., 29 Jul 2014, In : Investigative Ophthalmology and Visual Science. 55, 8, p. 5370-5379 10 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

Network analysis: a new approach to study endocrine disorders

Stevens, A., De Leonibus, C., Hanson, D., Dowsey, A. W., Whatmore, A., Meyer, S., Donn, R. P., Chatelain, P., Banerjee, I., Cosgrove, K. E., Clayton, P. E. & Dunne, M. J., Feb 2014, In : Journal of Molecular Endocrinology. 52, 1, p. R79-93

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Numerical compression schemes for proteomics mass spectrometry data

Teleman, J., Dowsey, A. W., Gonzalez-Galarza, F. F., Perkins, S., Pratt, B., Röst, H. L., Malmström, L., Malmström, J., Jones, A. R., Deutsch, E. W. & Levander, F., 2014, In : Molecular and Cellular Proteomics. 13, 6, p. 1537-1542 6 p.

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)
2011

Cardiovascular magnetic resonance tagging of the right ventricular free wall for the assessment of long axis myocardial function in congenital heart disease

Chen, S. S. M., Keegan, J., Dowsey, A. W., Ismail, T., Wage, R., Li, W., Yang, G. Z., Firmin, D. N. & Kilner, P. J., 2011, In : Journal of Cardiovascular Magnetic Resonance. 13, 1, 80.

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)
2010

Guidelines for reporting the use of gel image informatics in proteomics

Hoogland, C., O'Gorman, M., Bogard, P., Gibson, F., Berth, M., Cockell, S. J., Ekefjärd, A., Forsstrom-Olsson, O., Kapferer, A., Nilsson, M., Martínez-Bartolomé, S., Albar, J. P., Echevarría-Zomẽo, S., Martínez-Gomariz, M., Joets, J., Binz, P. A., Taylor, C. F., Dowsey, A. & Jones, A. R., 2010, In : Nature Biotechnology. 28, 7, p. 655-656 2 p.

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)

Image analysis tools and emerging algorithms for expression proteomics

Dowsey, A. W., English, J. A., Lisacek, F., Morris, J. S., Yang, G. Z. & Dunn, M. J., Dec 2010, In : Proteomics. 10, 23, p. 4226-4257 32 p.

Research output: Contribution to journalArticle (Academic Journal)

41 Citations (Scopus)

MR image-based geometric and hemodynamic investigation of the right coronary artery with dynamic vessel motion

Torii, R., Keegan, J., Wood, N. B., Dowsey, A. W., Hughes, A. D., Yang, G. Z., Firmin, D. N., Thom, S. A. M. & Xu, X. Y., Aug 2010, In : Annals of Biomedical Engineering. 38, 8, p. 2606-2620 15 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)
2009

Fluid-structure interaction analysis of a patient-specific right coronary artery with physiological velocity and pressure waveforms

Torii, R., Wood, N. B., Hadjiloizou, N., Dowsey, A. W., Wright, A. R., Hughes, A. D., Davies, J., Francis, D. P., Mayet, J., Yang, G. Z., Thom, S. A. M. & Xu, X. Y., 2009, In : Communications in Numerical Methods in Engineering. 25, 5, p. 565-580 16 p.

Research output: Contribution to journalArticle (Academic Journal)

85 Citations (Scopus)

Stress phase angle depicts differences in coronary artery hemodynamics due to changes in flow and geometry after percutaneous coronary intervention

Torii, R., Wood, N. B., Hadjiloizou, N., Dowsey, A. W., Wright, A. R., Hughes, A. D., Davies, J., Francis, D. P., Mayet, J., Yang, G. Z., Thom, S. A. M. & Xu, X. Y., Mar 2009, In : AJP - Heart and Circulatory Physiology. 296, 3, p. H765-H776

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

The effect of dynamic vessel motion on haemodynamic parameters in the right coronary artery: A combined MR and CFD study

Torii, R., Keegan, J., Wood, N. B., Dowsey, A. W., Hughes, A. D., Yang, G. Z., Firmin, D. N., McG Thom, S. A. & Xu, X. Y., 1 Jan 2009, In : British Journal of Radiology. 82, SPEC. ISSUE 1

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)
2008

Automated image alignment for 2D gel electrophoresis in a high-throughput proteomics pipeline

Dowsey, A. W., Dunn, M. J. & Yang, G. Z., Apr 2008, In : Bioinformatics. 24, 7, p. 950-957 8 p.

Research output: Contribution to journalArticle (Academic Journal)

30 Citations (Scopus)

The future of large-scale collaborative proteomics

Dowsey, A. W. & Yang, G. Z., Aug 2008, In : Proceedings of the IEEE. 96, 8, p. 1292-1309 18 p., 4567693.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)
2006

Adaptive cardiovascular imaging: Challenges and opportunities for real-time processing

Dowsey, A. W., Merrifield, R. D. & Yang, G. Z., Sep 2006, In : IEEE Signal Processing Magazine. 23, 5, p. 112-116 5 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)

Examination of 2-DE in the Human Proteome Organisation Brain Proteome Project pilot studies with the new RAIN gel matching technique

Dowsey, A. W., English, J., Pennington, K., Cotter, D., Stuehler, K., Marcus, K., Meyer, H. E., Dunn, M. J. & Yang, G. Z., Sep 2006, In : Proteomics. 6, 18, p. 5030-5047 18 p.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

The HUPO Brain Proteome Project Jamboree: Centralised summary of the pilot studies

Hamacher, M., Stephan, C., Blüggel, M., Chamrad, D., Körting, G., Martens, L., Müller, M., Hermjakob, H., Parkinson, D., Dowsey, A., Reidegeld, K. A., Marcus, K., Dunn, M. J., Meyer, H. E. & Apweiler, R., Mar 2006, In : Proteomics. 6, 6, p. 1719-1721 3 p.

Research output: Contribution to journalArticle (Academic Journal)

2 Citations (Scopus)
2005

The road to high-throughput proteomics

Dowsey, A. & Yang, G. Z., Sep 2005, In : EBR - European Biopharmaceutical Review. AUTUMN, p. 30-34 5 p.

Research output: Contribution to journalArticle (Academic Journal)

2004

ProteomeGRID: Towards a high-throughput proteomics pipeline through opportunistic cluster image computing for two-dimensional gel electrophoresis

Dowsey, A. W., Dunn, M. J. & Yang, G. Z., Dec 2004, In : Proteomics. 4, 12, p. 3800-3812 13 p.

Research output: Contribution to journalArticle (Academic Journal)

15 Citations (Scopus)
2003

The role of bioinformatics in two-dimensional gel electrophoresis

Dowsey, A. W., Dunn, M. J. & Yang, G. Z., 1 Aug 2003, In : Proteomics. 3, 8, p. 1567-1596 30 p.

Research output: Contribution to journalArticle (Academic Journal)

152 Citations (Scopus)