Dr Anita C Thomas

Ass.Dip.App.Biol., B.App.Sci., M.Sc., Ph.D.(Qld.)

  • BS2 8HW

1989 …2020

Research output per year

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Research Output

2020

Coronary artery mechanics induces human saphenous vein remodelling via recruitment of adventitial myofibroblast-like cells mediated by Thrombospondin-1

Garoffolo, G., Ruiter, M. S., Piola, M., Brioschi, M., Thomas, A. C., Agrifoglio, M., Polvani, G., Coppadoro, L., Zoli, S., Saccu, C., Spinetti, G., Banfi, C., Fiore, G. B., Madeddu, P., Soncini, M. & Pesce, M., 3 Feb 2020, In : Theranostics. 10, 6, p. 2597-2611 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
25 Downloads (Pure)

Galectin-3 identifies a subset of macrophages with a potential beneficial role in atherosclerosis: Macrophage galectin-3 prevents plaque progression

Di Gregoli, K., Somerville, M., Bianco, R., Thomas, A. C., Frankow, A., Newby, A. C., George, S. J., Jackson, C. L. & Johnson, J. L., 28 May 2020, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 40, p. 1491-1509 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Downloads (Pure)
Open Access
File
29 Downloads (Pure)

Multi-omics analysis of diabetic heart disease in the db/db model reveals potential targets for treatment by a longevity-associated gene

Faulkner, A. R. M., Dang, Z., Avolio, E., Thomas, A. C., Batstone, T. E., Lloyd, G. R., Weber, R., Najdekr, L., Jankevics, A., Dunn, W., Spinetti, G., Vecchione, C., Puca, A. A. & Madeddu, P. R., 21 May 2020, In : Cells. 9, 5, 5 p., 1283.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
17 Downloads (Pure)
2019

miR-15a/-16 Inhibit Angiogenesis by Targeting the Tie2 Coding Sequence: Therapeutic Potential of a miR-15a/16 Decoy System in Limb Ischemia

Besnier, M., Shantikumar, S., Anwar, M., Dixit, P., Chamorro-Jorganes, A., Sweaad, W., Sala-Newby, G., Madeddu, P., Thomas, A. C., Howard, L., Mushtaq, S., Petretto, E., Caporali, A. & Emanueli, C., 6 Sep 2019, In : Molecular Therapy - Nucleic Acids. 17, p. 49-62 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
119 Downloads (Pure)

Nerve growth factor gene therapy improves bone marrow sensory innervation and nociceptor-mediated stem cell release in a mouse model of type 1 diabetes with limb ischaemia

Dang, Z., Avolio, E., Albertario, A., Sala-Newby, G., Thomas, A., Wang, N., Emanueli, C. & Madeddu, P., 1 Jul 2019, In : Diabetologia. 62, 7, p. 1297-1311 15 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
5 Citations (Scopus)
267 Downloads (Pure)

Role of TPBG (Trophoblast Glycoprotein) Antigen in Human Pericyte Migratory and Angiogenic Activity

Spencer, H. L., Jover, E., Cathery, W., Avolio, E., Rodriguez-Arabaolaza, I., Thomas, A. C., Alvino, V. V., Sala-Newby, G., Dang, Z., Fagnano, M., Reni, C., Rowlinson, J., Vono, R., Spinetti, G., Beltrami, A. P., Gargioli, C., Caporali, A., Angelini, G. & Madeddu, P., 1 Jun 2019, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 6, p. 1113-1124 12 p.

Research output: Contribution to journalArticle (Academic Journal)

1 Citation (Scopus)
2018

Layered double hydroxide nanoparticles: Impact on vascular cells, blood cells and the complement system

Gu, Z., Yan, S., Cheong, S., Cao, Z., Zuo, H., Thomas, A. C., Rolfe, B. E. & Xu, Z. P., 15 Feb 2018, In : Journal of Colloid and Interface Science. 512, p. 404-410 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
262 Downloads (Pure)
2017

A humanized HLA-DR4 mouse model for autoimmune myocarditis

Emrah Şelli, M., Thomas, A. C., Wraith, D. C. & Newby, A. C., Jun 2017, In : Journal of Molecular and Cellular Cardiology. 107, p. 22-26

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
2 Citations (Scopus)
208 Downloads (Pure)
2016

Plaque size is decreased but M1 macrophage polarization and rupture related metalloproteinase expression are maintained after deleting T-bet in ApoE null mice

Tsaousi, A., Hayes, E., Di Gregoli, K., Bond, A., Bevan, L., Thomas, A. & Newby, A., 17 Feb 2016, In : PLoS ONE. 11, 2, p. e0148873 28 p., e0148873.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
285 Downloads (Pure)

Strategies to extend the life of saphenous vein grafts

Thomas, A., Angelini, G. & Zakkar, M., 2016, Coronary Graft Failure: State of the Art. Tintoiu, IC., Underwood, MJ., Cook, SP., Kitabata, H. & Abbas, A. (eds.). Switzerland: Springer, p. 585-597 13 p. Chapter 50

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Targeting therapies to treat restenosis and vein graft disease

Thomas, A., 2016, Coronary Graft Failure – State of the Art. Tintoiu, IC., Underwood, MJ., Cook, SP., Kitabata, H. & Abbas, A. (eds.). Switzerland: Springer, p. 715-723 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

2015

Foam cell formation in vivo converts macrophages to a pro-fibrotic phenotype

Thomas, A., Eijgelaar, W., Daemen, MJAP. & Newby, A., 31 Jul 2015, In : PLoS ONE. 10, 7, 27 p., e0128163.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
22 Citations (Scopus)
340 Downloads (Pure)

Foam cell formation in vivo is pro-fibrotic

Newby, A. & Thomas, A., 2015, Atherosclerosis. Vol. 241. p. e81-e82 2 p. EAS-0623

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Genomic profile of foamy and non-foamy granuloma macrophages from fat-fed ApoE null mice or control mice fed a normal diet

Thomas, A., Eijgelaar, W., Daemen, MJ. & Newby, A., 2015, NCBI.

Research output: Other contribution

Open Access

Macrophage: SHIP of immunity

Mills, C. D., Thomas, A. C., Lenz, L. L. & Munder, M., Mar 2015, M1/M2 Macrophages: The Arginine Fork in the Road to Health and Disease. Mills, C., Lenz, L. & Ley, K. (eds.). USA: Frontiers Media S.A., p. 42-46 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Nitric oxide synthase: Non-canonical expression patterns

Mattila, J. & Thomas, A. C., Mar 2015, M1/M2 macrophages: The arginine fork in the road to health and disease. Mills, C., Lenz, L. & Ley, K. (eds.). USA: Frontiers Media S.A., p. 170-174 5 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

The pro-fibrotic and anti-inflammatory foam cell macrophage paradox

Thomas, A. C., Eigelaar, W., Daemen, M. & Newby, A. C., Dec 2015, In : Genomics Data. 6, p. 136-138 3 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
296 Downloads (Pure)

’Of mice and men’: Arginine metabolism in human macrophages

Thomas, A. C. & Mattila, J., Mar 2015, M1/M2 macrophages: The arginine fork in the road to health and disease. Mills, C., Lenz, L. & Ley, K. (eds.). USA: Frontiers Media S.A., p. 73-79 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

2014

Classical and Alternative Activation and Metalloproteinase Expression Occurs in Foam Cell Macrophages in Male and Female ApoE Null Mice in the Absence of T and B Lymphocytes

Hayes, E. M., Tsaousi, A., Di Gregoli, K., Jenkinson, S. R., Bond, A. R., Johnson, J. L., Bevan, L. A., Thomas, A. C. & Newby, A. C., 28 Oct 2014, In : Frontiers in Immunology. 5, 16 p., 537.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)
7 Downloads (Pure)

Classical and alternative activation and metalloproteinase expression occurs in foam cell macrophages in the absence of T- and B-lymphocytes

Thomas, A. C., Hayes, E. M., Tsaousi, A., Di Gregoli, K., Jenkinson, S. R., Bevan, L. A., Johnson, J. L. & Newby, A. C., 2014, p. P730.

Research output: Contribution to conferenceConference Abstract

Deleting Th1-lymphocytes influences macrophage activation and metalloproteinase expression in ApoE null mice.

Tsaousi, A., Hayes, E. M., Thomas, A. C., Bevan, L. A. & Newby, A. C., 2014, p. A97.

Research output: Contribution to conferenceConference Abstract

Foam cell macrophages increase fibrosis: a new paradox.

Thomas, A. C., Eijgelaar, W., Daemen, M., Hayes, E. M., Bevan, L. A., Johnson, J. L., White, S. J. & Newby, A. C., 2014, Cardiovascular Research. Vol. 103. p. P731

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Macrophage: SHIP of Immunity

Mills, C. D., Thomas, A. C., Lenz, L. L. & Munder, M., Dec 2014, In : Frontiers in Immunology. 5, 5 p., 620.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
27 Citations (Scopus)
283 Downloads (Pure)

Nitric oxide synthase: non-canonical expression patterns

Mattila, J. & Thomas, A. C., 9 Oct 2014, In : Frontiers in Immunology. 5, 5 p., 478.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
57 Citations (Scopus)
323 Downloads (Pure)

“Of mice and men”: arginine metabolism in human macrophages

Thomas, A. C. & Mattila, J., 7 Oct 2014, In : Frontiers in Immunology. 5, 7 p., 479.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
71 Citations (Scopus)
282 Downloads (Pure)
2013

Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques

Fromel, T., Kohlstedt, K., Rudiger, P., Yin, X., Awwad, K., Barbosa-Sicard, E., Thomas, A. C., Lieberz, R., Mayr, M. & Fleming, I., 2013, In : Basic Research in Cardiology. 108, p. 319-331 13 p., doi: 10.1007/s00395-012-0319-8.

Research output: Contribution to journalArticle (Academic Journal)

23 Citations (Scopus)

Metalloproteinases in acute venous occlusion

Thomas, A. C., 2013, Inflammatory Response in Cardiovascular Surgery. Gabriel, E. & Gabriel, S. (eds.). London: Springer London, p. 141-151 11 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

1 Citation (Scopus)

Restenosis treatments using nanoparticle-based drug delivery systems

Gu, Z., Rolfe, B., Thomas, A. C. & Xu, Z-P., Oct 2013, In : Current Pharmaceutical Design. 19, 35, p. 6330-6339 10 p., 10.1016/j.coph.2012.01.002.

Research output: Contribution to journalArticle (Academic Journal)

9 Citations (Scopus)
2012

Animal models for studying vein graft failure and therapeutic interventions

Thomas, A. C., Apr 2012, In : Current Opinion in Pharmacology. 12, 2, p. 121-126 6 p.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

Antibody-targeted drug delivery to injured arteries using layered double hydroxide nanoparticles

Gu, Z., Rolfe, B., Xu, Z-P., Campbell, J., Lu, GQM. & Thomas, A. C., 2012, In : Advanced Healthcare Materials. 1, p. 669-673 5 p.

Research output: Contribution to journalArticle (Academic Journal)

31 Citations (Scopus)

Heparin-related nanomaterials

Gu, Z., Rolfe, B., Thomas, A. C., Campbell, J., Lu, GQ. M. & Xu, Z-P., 2012, Heparin: Properties, Uses and Side Effects. Piyathilake, D. E. & Liang, R. (eds.). New York: New York: Nova Science, p. 159-178 19 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

Targeted delivery for treatments for restenosis and vein graft disease

Thomas, A. C., 4 Nov 2012, In : ISRN Vascular Medicine. 2012, p. 1-24 24 p., 710765.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
319 Downloads (Pure)
2011

Cellular trafficking of low molecular weight heparin incorporated in layered double hydroxide nanoparticles in rat vascular smooth muscle cells

Gu, Z., Rolfe, B., Xu, Z-P., Thomas, A. C., Campbell, J. & Lu, GQ., 2011, In : Biomaterials. 32, p. 7234-7240 7 p.

Research output: Contribution to journalArticle (Academic Journal)

55 Citations (Scopus)

Complement C5a receptor inhibition reduces atherosclerosis in ApoE-/- mice.

Manthey, H., Thomas, A. C., Shiels, I., Zerneke, A., Woodruff, T., Rolfe, B. & Taylor, S., 2011, In : FASEB Journal. 25, p. 2447-2455 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Neointima formed by arterial smooth muscle cells expressing versican variant V3 is resistant to lipid and macrophage accumulation

Merrilees, M., Beaumont, B., Braun, K., Thomas, A. C., Kang, I., Hinek, A., Passi, A. & Wight, T., 2011, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 31, p. 1309-1316 8 p.

Research output: Contribution to journalArticle (Academic Journal)

30 Citations (Scopus)
2010

Animal Models for Studying Neointima Formation

Jeremy, JY. & Thomas, AC., Mar 2010, In : Current Vascular Pharmacology. 8(2), p. 198 - 219 12 p.

Research output: Contribution to journalArticle (Academic Journal)

16 Citations (Scopus)

Does macrophage foam cell formation promote extracellular matrix formation of degradation? A genomic study

Thomas, A. C., Johnson, J. L., Eigelaar, W., Daemen, M. & Newby, A. C., 2010, Heart. Vol. 96. p. e14

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Effect of matrix metalloproteinase-9 knockout on vein graft remodelling in mice

Thomas, AC. & Newby, AC., May 2010, In : Journal of Vascular Research. 47(4), p. 299 - 308 10 p.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

Effect of matrix metalloproteinase-9 knockout on vein graft remodelling in mice

Thomas, A. C. & Newby, A. C., 9 Aug 2010, In : Journal of Vascular Research. 47, 4, p. 299-308 10 p., DOI: 10.1159/000265564.

Research output: Contribution to journalArticle (Academic Journal)

24 Citations (Scopus)

Enhanced effects of low molecular weight heparin carried by layered double hydroxide nanoparticles on rat vascular smooth muscle cells

Gu, Z., Rolfe, B., Xu, Z-P., Thomas, A. C., Campbell, J. & Lu, GQ., 2010, In : Biomaterials. 31, 20, p. 5455-5462 8 p.

Research output: Contribution to journalArticle (Academic Journal)

Genomic differences between mouse foamy and non-foamy macrophages

Thomas, A. C., Eijgelaar, W., Daemen, M. & Newby, A. C., 2010, Atherosclerosis Suppliments. Vol. 11. p. 103-104 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

2009

Reduction of early vein graft thrombosis by locally-delivered tissue plasminogen activator gene transfer.

Thomas, A. C., Wyatt, M. J. & Newby, A. C., 2009, Heart. Vol. 95. p. Nov15

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

Reduction of early vein graft thrombosis by tissue plasminogen activator gene transfer

Thomas, AC., Wyatt, MJ. & Newby, AC., Jul 2009, In : Thrombosis and Haemostasis. 102(1), p. 145 - 152 8 p.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes

Newby, AC., George, SJ., Ismail, Y., Johnson, JL., Sala-Newby, GB. & Thomas, AC., Jun 2009, In : Thrombosis and Haemostasis. 101(6), p. 1006 - 1011 6 p.

Research output: Contribution to journalArticle (Academic Journal)

93 Citations (Scopus)
2008

In vitro sustained release of LMWH from MgAl-layered double hydroxide nanohybrids

Gu, Z., Thomas, A. C., Xu, Z. P., Campbell, J. & Lu, G. Q., 2008, In : Chemistry of Materials. 20, 11, p. 3715-3722 8 p.

Research output: Contribution to journalArticle (Academic Journal)

208 Citations (Scopus)

Protective effects of C5a receptor antagonism in a mouse model of atherosclerosis

Manthey, H., Thomas, A. C., Taylor, S., Woodruff, T., Moore, T., Shiels, I. & Rolfe, B., 2008, Molecular Immunology. Vol. 45. p. 4151

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)

2007

Genomics of Foam Cells and Nonfoamy Macrophages From Rabbits Identifies Arginase-I as a Differential Regulator of Nitric Oxide Production

Thomas, AC., Sala-Newby, GB., Ismail, Y., Johnson, JL., Pasterkamp, G. & Newby, AC., Mar 2007, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 27 (3), p. 571 - 577 7 p.

Research output: Contribution to journalArticle (Academic Journal)

55 Citations (Scopus)
2006

Conversion of macrophages to foam cells upregulates production of several matrix metalloproteinases: role of ox-LDL

Ismail, Y., Sala-Newby, G., Thomas, A. C. & Newby, A. C., 2006, European Heart Journal. Vol. 27. p. 969

Research output: Chapter in Book/Report/Conference proceedingConference Contribution (Conference Proceeding)