Research Output per year
Personal profile
Research interests
I am a Clinical Lecturer at Bristol Children’s Vaccine Centre and the School of Cellular and Molecular Medicine, while completing my subspecialist training in Paediatric Immunology & Infectious Diseases at Bristol Royal Hospital for Children.
My research explores how we can design new and better vaccines through understanding the function of immune cells that reside in the respiratory tract. I developed my interest in respiratory immunity while studying macrophage function in the laboratory of Professor Tracy Hussell during my PhD which was funded by fellowships from the Medical Research Council and European Society of Paediatric Infectious Diseases (ESPID). Now, I am interested in how we can develop a vaccine for group A Streptococcus (GAS) by profiling the antigen-specific response of respiratory lymphoid tissue. GAS infection is a neglected global disease that not only causes sore throat, but also kills more than half a million people every year by causing invasive infections and rheumatic heart disease.
My current research in group A Streptococcus vaccine antigen discovery is funded by grants from Above and Beyond and ESPID. I am also undertaking COVID-19 research funded by the Elizabeth Blackwell Institute and the Grand Appeal.
I also contribute to both undergraduate and postgraduate teaching. Currently, I chair the ESPID Walter Marget Workshop as well as co-chair RCPCH Child Health in Low-Resource Settings.
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Research Output
Neutrophil dysfunction triggers inflammatory bowel disease in G6PC3 deficiency
Goenka, A., Doherty, J. A., Al-Farsi, T., Jagger, C., Banka, S., Cheesman, E., Fagbemi, A., Hughes, S. M., Wynn, R. F., Hussell, T. & Arkwright, P. D., 15 Sep 2020, In : Journal of Leukocyte Biology. 8 p.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
Human mast cells exhibit an individualized pattern of antimicrobial responses
Garcia-Rodriguez, K. M., Bahri, R., Sattentau, C., Roberts, I. S., Goenka, A. & Bulfone-Paus, S., 28 Mar 2020, In : Immunity, Inflammation and Disease. 13 p.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
Infant alveolar macrophages are unable to effectively contain Mycobacterium tuberculosis
Goenka, A., Prise, I., Connolly, E., Fernandez-Soto, P., Morgan, D., Cavet, J., Grainger, J., Nichani, J., Arkwright, P. & Hussell, T., 24 Mar 2020, In : Frontiers in Immunology.Research output: Contribution to journal › Article (Academic Journal)
Open Access
File
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