Projects per year
Personal profile
Research interests
I am a Research Fellow at the MRC Integrative Epidemiology Unit (IEU) based at The University of Bristol. My current research is focussed on identifying genetic variants for atopic dermatitis (eczema) in multiple ancestries, and investigating causal risk factors by applying Mendelian Randomization techniques. I am also involved in research with the EAGLE eczema consortium which aims to use eczema and genetic data to improve our understanding of disease. I work with a number of datasets including UK Biobank and ALSPAC (Avon Longitudinal Study of Parents and Children).
Prior to this role I gained my BSc in Medical Genetics from the University of Leicester, and my MSc in Human Molecular Genetics from Imperial College London. I completed my PhD at The University of Manchester in 2016 where I investigated novel susceptibility loci for Psoriatic Arthritis. This involved performing genetic and bioinformatic analysis with large datasets to identify and characterise novel susceptibility loci for disease.
External positions
PhD Student, NIHR Manchester Musculoskeletal Biomedical Research Unit
1 Oct 2012 → 30 Sept 2016
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Collaborations and top research areas from the last five years
Projects
- 2 Finished
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Final Costs: Investigating risk factors of inflammatory related disease
1/10/18 → 31/10/18
Project: Research
Research output
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Imputation provides an opportunity to study filaggrin (FLG) null mutations in large population cohorts that lack bespoke genotyping
Paternoster, L., Budu-Aggrey, A. & Brown, S. J., 1 Feb 2022, In: Wellcome Open Research. 7, 9 p., 36.Research output: Contribution to journal › Article (Academic Journal)
Open AccessFile32 Downloads (Pure) -
Four childhood atopic dermatitis subtypes identified from trajectory and severity of disease and internally validated in a large UK birth cohort
Mulick, A. R., Mansfield, K. E., Silverwood, R. J., Budu-Aggrey, A., Roberts, A., Custovic, A., Pearce, N., Irvine, A. D., Smeeth, L., Abuabara, K. & Langan, S. M., Sept 2021, In: British Journal of Dermatology. 185, 3, p. 526-536 11 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access11 Citations (Scopus) -
Identification of OCA2 as a novel locus for the co-morbidity of asthma-plus-eczema
Margaritte-Jeannin, P., Budu-Aggrey, A., Ege, M., Madore, A-M., Linhard, C., Mohamdi, H., von Mutius, E., Granell, R., Demenais, F., Laprise, C., Bouzigon, E. & Dizier, M-H., 22 Jun 2021, (E-pub ahead of print) In: Clinical and Experimental Allergy. 52, 1, p. 70-81 12 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile2 Citations (Scopus)35 Downloads (Pure)