Research output per year
Research output per year
Personal profile
Research interests
My research in the area of paediatric rheumatology includes:
- Randomised controlled trials of novel biological drugs in children with JIA associated uveitis. I am the Co-Chief Investigator of Sycamore Trial (RCT of adalimumab in JIA associated uveitis) funded by HTA/ARUK. I am also the Co-Chief Investigator of a trial of Tocilizumab in anti TNF refractory JIA associated uveitis.
- Leading on new agents for management of refractory arthritis in collaboration with industry
- Design and conduct studies in rare disease using novel study designs (Bayesian and Simon design)
- Looking at diagnostic markers and new therapies for MAS or secondary HLH
- Collaboration with colleagues in India on secondary HLH in Dengue fever
- Basic science studies on understanding pathogenesis of lupus nephritis
- Biomarkers in JIA and JIA associated uveitis.
Activities/Findings:
- Associate Editor – Archives of Diseases in Childhood
- Editorial Board – Rheumatology
- Scientific Member, ARUK/MCRN Paediatric Rheumatology Clinical Studies Group
- Associate Director of ARUK funded only Paediatric Experimental Arthritis Treatment Centre leading on JIA-Uveitis and Industry workstreams
- Medical Advisor for National Rheumatoid Arthritis Society (NRAS) and National Ankylosing Spondylitis Society (NASS)
- Research Advisor for RCPCH Paediatric Rheumatology CSAC.
External positions
Co-Editor
2021 → …
Associate Director, ARUK Paediatric Rheumatology Experimental Arthritis Treatment Centre leading on Industry and Uveitis workstreams
2014 → …
Associate Editor, Archives of Diseases in Childhood
2010 → …
Scientific Member and Champion, MCRN/ARUK Paediatric Rheumatology Clinical Studies Group
2007 → 2023
Bristol Royal Hospital for Children, UK
2004 → …
Keywords
- Randomised controlled trials in paediatric rheumatology, Paediatric Uveitis Immunomodulatory therapy, Trials of novel biological agents including using adaptive designs, Musculoskeletal problems in children, Kawasaki disease
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Adaptive and innovative study design in rare diseases
Ramanan, A. V. & Wason, J. M. S., 5 Jun 2024, (E-pub ahead of print) In: Archives of Disease in Childhood. 110, 1, p. 1-3 3 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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A de novo TLR7 gain-of-function mutation causing severe monogenic lupus in an infant
Stremenova Spegarova, J., Sinnappurajar, P., Al Julandani, D., Navickas, R., Griffin, H., Ahuja, M., Grainger, A., Livingstone, K., Rice, G. I., Sutherland, F., Hayes, C., Parke, S., Pang, L., Roderick, M. R., Slatter, M., Crow, Y., Ramanan, A. V. & Hambleton, S., 16 May 2024, In: Journal of Clinical Investigation. 134, 13, 3 p., e179193.Research output: Contribution to journal › Letter (Academic Journal)
Open Access4 Citations (Scopus) -
British Society for Rheumatology guideline on management of adult and juvenile onset Sjögren disease
Price, E. J., Benjamin, S., Bombardieri, M., Bowman, S., Carty, S., Ciurtin, C., Crampton, B., Dawson, A., Fisher, B. A., Giles, I., Glennon, P., Gupta, M., Hackett, K. L., Larkin, G., Ng, W.-F., Ramanan, A. V., Rassam, S., Rauz, S., Smith, G. & Sutcliffe, N. & 2 others, , 16 Apr 2024, (E-pub ahead of print) In: Rheumatology. 33 p., keae152.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access
Datasets
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Additional file 2 of Juvenile idiopathic arthritis polygenic risk scores are associated with cardiovascular phenotypes in early adulthood: a phenome-wide association study
Clarke, S. L. N. (Creator), Jones, H. J. (Creator), Sharp, G. C. (Creator), Easey, K. E. (Creator), Hughes, A. D. (Creator), Ramanan, A. V. (Creator) & Relton, C. L. (Creator), figshare, 21 Nov 2022
DOI: 10.6084/m9.figshare.21593823, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Juvenile_idiopathic_arthritis_polygenic_risk_scores_are_associated_with_cardiovascular_phenotypes_in_early_adulthood_a_phenome-wide_association_study/21593823 and one more link, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Juvenile_idiopathic_arthritis_polygenic_risk_scores_are_associated_with_cardiovascular_phenotypes_in_early_adulthood_a_phenome-wide_association_study/21593823/1 (show fewer)
Dataset
Prizes
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Awarded the Best Clinical Science Abstract Award (1 of 6) at the European League Against Rheumatism Annual Conference, London 2016
Ramanan, A. V. (Recipient), 2016
Prize: Prizes, Medals, Awards and Grants
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Best Clinical Science Abstract Award (1 of 6) at the European League Against Rheumatism Annual Conference, London 2016
Ramanan, A. V. (Recipient), 2016
Prize: Prizes, Medals, Awards and Grants
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Bristol Post/Bristol Health Partners Research Impact Award
Ramanan, A. V. (Recipient), 2016
Prize: Prizes, Medals, Awards and Grants