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Personal profile

Research interests

My research in the area of paediatric rheumatology includes:

  • Randomised controlled trials of novel biological drugs in children with JIA associated uveitis. I am the Co-Chief Investigator of Sycamore Trial (RCT of adalimumab in JIA associated uveitis) funded by HTA/ARUK. I am also the Co-Chief Investigator of a trial of Tocilizumab in anti TNF refractory JIA associated uveitis.
  • Leading on new agents for management of refractory arthritis in collaboration with industry
  • Design and conduct studies in rare disease using novel study designs (Bayesian and Simon design)
  • Looking at diagnostic markers and new therapies for MAS or secondary HLH
  • Collaboration with colleagues in India on secondary HLH in Dengue fever
  • Basic science studies on understanding pathogenesis of lupus nephritis
  • Biomarkers in JIA and JIA associated uveitis.

Activities/Findings:

  • Associate Editor – Archives of Diseases in Childhood
  • Editorial Board – Rheumatology
  • Scientific Member, ARUK/MCRN Paediatric Rheumatology Clinical Studies Group
  • Associate Director of ARUK funded only Paediatric Experimental Arthritis Treatment Centre leading on JIA-Uveitis and Industry workstreams
  • Medical Advisor for National Rheumatoid Arthritis Society (NRAS) and National Ankylosing Spondylitis Society (NASS)
  • Research Advisor for RCPCH Paediatric Rheumatology CSAC.

External positions

Associate Director, ARUK Paediatric Rheumatology Experimental Arthritis Treatment Centre leading on Industry and Uveitis workstreams

2014 → …

Associate Editor, Archives of Diseases in Childhood

2010 → …

Scientific Member and Champion, MCRN/ARUK Paediatric Rheumatology Clinical Studies Group

2007 → …

Bristol Royal Hospital for Children & Royal National Hospital for Rheumatic Diseases, Bath, UK

2004 → …

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