Ben G Faber

2025

A novel classifier of radiographic knee osteoarthritis for use on knee DXA images is predictive of joint replacement in UK Biobank

Beynon, R. A., Saunders, F. R., Ebsim, R., Faber, B. G., Jung, M., Gregory, J., Lindner, C., Aspden, R. M., Harvey, N. C., Cootes, T. & Tobias, J. H., 20 Jan 2025, (E-pub ahead of print) In: Rheumatology Advances in Practice. rkaf009.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Associations between work characteristics and osteoarthritis: a cross-sectional study of 285,947 UK Biobank participants

Hashmi, A., Scott, S., jung, M., Meng, Q. J., Tobias, J. H., Beynon, R. A. & Faber, B. G., 10 Jan 2025, (E-pub ahead of print) In: Osteoarthritis and Cartilage Open. 7, 1, 100565.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Cardiovascular risk assessment for osteoporosis patients considering Romosozumab

Macrae, F., Clark, E. M., Walsh, K., Bailey, S. J., Roy, M., Hardcastle, S., Cockill, C., Tobias, J. H. & Faber, B. G., 1 Jan 2025, In: Bone. 190, 2 p., 117305.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

2 Citations (Scopus)

32 Downloads (Pure)

2024

42.Mendelian Randomization

Gormley, M., Faber, B. G. & Davey Smith, G., 21 Mar 2024, (Accepted/In press) Vogel and Motulsky's Human Genetics: Problems and Approaches . Springer Nature

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Dual-energy X-ray absorptiometry derived knee shape may provide a useful imaging biomarker for predicting total knee replacement: Findings from a study of 37,843 people in UK Biobank

Beynon, R. A., Saunders, F. R., Ebsim, R., Frysz, M. R., Faber, B. G., Gregory, J. S., Lindner, C., Sarmanova, A., Aspden, R. M., Harvey, N. & Tobias, J. H., 1 Jun 2024, In: Osteoarthritis and Cartilage Open. 6, 2, 100468.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

4 Citations (Scopus)

Femoral neck width genetic risk score is a novel independent risk factor for hip fractures

Tobias, J., Nethander, M., Faber, B. G., Heppenstall, S., Ebsim, R., Cootes, T., Lindner, C., Saunders, F., Gregory, J., Aspden, R., Harvey, N., Kemp, J., Frysz, M. & Ohlsson, C., 1 Mar 2024, In: Journal of Bone and Mineral Research. 39, 3, p. 241-251 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

3 Citations (Scopus)

Hip shape shows a causal effect on hip fracture but not hip osteoarthritis: findings from a GWAS meta-analysis and causal analyses

Faber, B., Frysz, M., Zheng, J., Lin, H., Flynn, K., Ebsim, R., Saunders, F., Beynon, R., Gregory, J., Aspden, R., Harvey, N., Lindner, C., Cootes, T., Evans, D. M., Smith, G. D., Gao, X., Wang, S., Kemp, J. & Tobias, J., 26 Jan 2024

Research output: Other contribution

Sex differences in the radiographic and symptomatic prevalence of knee and hip osteoarthritis

Faber, B. G., Macrae, F., Jung, M., Zucker, B. E., Beynon, R. A. & Tobias, J. H., 16 Sept 2024, (Accepted/In press) In: Frontiers in Endocrinology. 15, 1445468.

Research output: Contribution to journal › Review article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

The genetic architecture of hip shape and its role in the development of hip osteoarthritis and fracture

Faber, B. G., Frysz, M. R., Zheng, J., Lin, H., Flynn, K., Ebsim, R., Saunders, F. R., Beynon, R. A., Gregory, J. S., Aspden, R. M., Harvey, N. C., Lindner, C., Cootes, T., Evans, D., Davey Smith, G., Gao, X., Wang, S., Kemp, J. P. & Tobias, J. H., 22 Nov 2024, (E-pub ahead of print) In: Human Molecular Genetics. 11 p., ddae169.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2023

A Genome-Wide Association Study Meta-Analysis of Alpha Angle Suggests Cam-Type Morphology May Be a Specific Feature of Hip Osteoarthritis in Older Adults

Faber, B. G., Frysz, M., Hartley, A. E., Ebsim, R., Boer, C. G., Saunders, F. R., Gregory, J. S., Aspden, R. M., Harvey, N. C., Southam, L., Giles, W., Le Maitre, C. L., Wilkinson, J. M., van Meurs, J. B. J., Zeggini, E., Cootes, T., Lindner, C., Kemp, J. P., Davey Smith, G. & Tobias, J. H., 20 Jan 2023, (E-pub ahead of print) In: Arthritis and Rheumatology. 75, 6, p. 900-909 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

7 Citations (Scopus)

90 Downloads (Pure)

Causal relationships between anthropometric traits, bone mineral density, osteoarthritis and spinal stenosis: A Mendelian randomisation investigation

Sobczyk-Barad, M. K., Faber, B. G., Southam, L., Frysz, M. R., Hartley, A. E., Zeggini, E., Tang, H., Gaunt, T. R. & al, E., 30 Dec 2023, In: Osteoarthritis and Cartilage. 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

Causal relationships between anthropometric traits, bone mineral density, osteoarthritis and spinal stenosis: a Mendelian randomization investigation

Sobczyk, M. K., Faber, B. G., Southam, L., Frysz, M., Hartley, A., Zeggini, E., Tang, H. & Gaunt, T. R., 15 Aug 2023

Research output: Other contribution

Comparison between UK Biobank and Shanghai Changfeng suggests distinct hip morphology may contribute to ethnic differences in the prevalence of hip osteoarthritis.

Zheng, J., Frysz, M. R., Faber, B. G., Lin, H., Ebsim, R., Ge, J., Yong, Y., Saunders, F. R., Gregory, J. S., Aspden, R. M., Harvey, N. C., Jiang, B.-H., Cootes, T., Lindner, C., Gao, X., Wang, S. & Tobias, J. H., 5 Nov 2023, (E-pub ahead of print) In: Osteoarthritis and Cartilage.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

4 Citations (Scopus)

Hip geometric parameters are associated with radiographic and clinical hip osteoarthritis: Findings from a cross-sectional study in UK Biobank

Heppenstall, S., Ebsim, R., Saunders, F. R., Lindner, C., Gregory, J., Aspden, R. M., Harvey, N. C., Cootes, T., Tobias, J. H., Frysz, M. R. & Faber, B. G., 11 Sept 2023, (E-pub ahead of print) In: Osteoarthritis and Cartilage. 31, 12, p. 1627-1635 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

4 Citations (Scopus)

The identification of distinct protective and susceptibility mechanisms for hip osteoarthritis: findings from a genome-wide association study meta-analysis of minimum joint space width and Mendelian randomisation cluster analyses

Faber, B. G., Frysz, M. R., Tobias, J. H., Davey Smith, G., Boer, C. G., Ebsim, R., van Meurs, J. B. J., Lindner, C., Cootes, T., Saunders, F. R., Aspden, R. M., Gregory, J. S., Lane, N. E., Evans, D. S., Zeggini, E., Southam, L., Kemp, J. P., Evans, D., Hartley, A. E. & Flynn, K. & 2 others, Lundberg, M. & Harvey, N. C., 1 Sept 2023, In: EBioMedicine. 95, 104759.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

10 Citations (Scopus)

2022

Automatic Segmentation of Hip Osteophytes in DXA Scans using U-Nets

Ebsim, R., Faber, B. G., Saunders, F. R., Frysz, M. R., Gregory, J. S., Harvey, N., Tobias, J. H., Lindner, C. & Cootes, T., 16 Sept 2022, Medical Image Computing and Computer Assisted Intervention – MICCAI 2022 - 25th International Conference, Proceedings. Wang, L., Dou, Q., Fletcher, P. T., Speidel, S. & Li, S. (eds.). Springer Nature, p. 3-12 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 13435 LNCS).

Research output: Chapter in Book/Report/Conference proceeding › Conference Contribution (Conference Proceeding)

Open Access

File

5 Citations (Scopus)

73 Downloads (Pure)

Deriving alpha angle from anterior-posterior dual-energy x-ray absorptiometry scans: an automated and validated approach

Faber, B. G., Ebsim, R., Saunders, F. R., Frysz, M., Smith, G. D., Cootes, T., Tobias, J. H. & Lindner, C., 19 Jul 2022, In: Wellcome Open Research. 6, 60, p. 1-11 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

4 Citations (Scopus)

High bone mass and cam morphology are independently related to hip osteoarthritis: findings from the High Bone Mass Cohort

Zucker, B. E., Ebsim, R., Lindner, C., Hardcastle, S. A., Cootes, T., Tobias, J. H., Whitehouse, M. R., Gregson, C. L., Faber, B. G. & Hartley, A. E., 6 Aug 2022, In: BMC Musculoskeletal Disorders. 23, 1, 11 p., 757.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

5 Citations (Scopus)

57 Downloads (Pure)

Machine-learning derived acetabular dysplasia and cam morphology are features of severe hip osteoarthritis: findings from UK Biobank

Frysz, M. R., Faber, B. G., Ebsim, R., Saunders, F. R., Lindner, C., Gregory, J. S., Aspden, R. M., Harvey, N., Cootes, T. & Tobias, J. H., 1 Sept 2022, In: Journal of Bone and Mineral Research. 37, 9, p. 1720-1732 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

11 Citations (Scopus)

102 Downloads (Pure)

UKRI MRC National Musculoskeletal Ageing Network: strategic prioritisation to increase healthy lifespan and minimise physical frailty

UKRI MRC National Musculoskeletal Ageing Network Study Group, Dec 2022, In: Archives of Osteoporosis. 17, 1, 147.

Research output: Contribution to journal › Editorial (Academic Journal) › peer-review

Open Access

3 Citations (Scopus)

2021

A novel semi-automated classifier of hip osteoarthritis on DXA images shows expected relationships with clinical outcomes in UK Biobank

Faber, B. G., Ebsim, R., Saunders, F. R., Frysz, M. R., Lindner, C., Gregory, J. S., Aspden, R. M., Harvey, N., Davey Smith, G., Cootes, T. & Tobias, J. H., 17 Dec 2021, (E-pub ahead of print) In: Rheumatology. 29 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

18 Citations (Scopus)

81 Downloads (Pure)

Cam morphology but neither acetabular dysplasia nor pincer morphology is associated with osteophytosis throughout the hip: findings from a cross-sectional study in UK Biobank

Faber, B. G., Frysz, M. R., Davey Smith, G., Tobias, J. H. & al., E., Nov 2021, In: Osteoarthritis and Cartilage. 29, 11, p. 1521-1529 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

15 Citations (Scopus)

58 Downloads (Pure)

Infliximab in a patient with treatment-resistant anti-SAE dermatomyositis

Hassan, N., Davies, E. J., Faber, B. G. & Gunawardena, H., 14 May 2021, In: Rheumatology (United Kingdom). 60, 5, p. E156-E158

Research output: Contribution to journal › Letter (Academic Journal) › peer-review

4 Citations (Scopus)

Osteophyte size and location on hip DXA scans are associated with hip pain: findings from a cross sectional study in UK Biobank

Faber, B. G., Ebsim, R., Saunders, F. R., Frysz, M. R., Lindner, C., Gregory, J. S., Aspden, R. M., Harvey, N., Cootes, T., Davey Smith, G. & Tobias, J. H., Dec 2021, In: Bone. 153, 32 p., 116146.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

16 Citations (Scopus)

29 Downloads (Pure)

2020

Early onset sarcoidosis (Blau syndrome): erosive and often misdiagnosed

Ellis, J. C., Faber, B. G., Uri, I. F. & Emerson, S. J., 22 Jan 2020, In: Rheumatology (Oxford, England). 59, 5, p. 1190

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

1 Citation (Scopus)

100 Downloads (Pure)

Subregional statistical shape modelling identifies lesser trochanter size as a possible risk factor for radiographic hip osteoarthritis, a cross-sectional analysis from the Osteoporotic Fractures in Men Study

Faber, B. G., Bredbenner, T., Baird, D. A., Gregory, J., Saunders, F., Giuraniuc, C., Aspden, R., Lane, N., Orwoll, E. & Tobias, J. H., 1 Aug 2020, In: Osteoarthritis and Cartilage. 28, 8, p. 1071-1078 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

14 Citations (Scopus)

56 Downloads (Pure)

2019

Unpicking observational relationships between hip shape and osteoarthritis: hype or hope?

Faber, B. G., Frysz, M. & Tobias, J. H., 21 Oct 2019, (E-pub ahead of print) In: Current Opinion in Rheumatology. 9 p.

Research output: Contribution to journal › Review article (Academic Journal) › peer-review

Open Access

File

10 Citations (Scopus)

219 Downloads (Pure)

2018

Identification of Novel Loci Associated With Hip Shape: A Meta-Analysis of Genomewide Association Studies

Baird, D. A., Evans, D. S., Kamanu, F. K., Gregory, J. S., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Aspden, R. M., Jenkins, D., Kiel, D. P., Orwoll, E. S., Cummings, S. R., Lane, N. E., Mullin, B. H., Williams, F. M. K., Richards, J. B., Wilson, S. G., Spector, T. D., Faber, B. G. & Lawlor, D. A. & 10 others, Grundberg, E., Ohlsson, C., Pettersson-Kymmer, U., Capellini, T. D., Richard, D., Beck, T. J., Evans, D. M., Paternoster, L., Karasik, D. & Tobias, J. H., 26 Nov 2018, (E-pub ahead of print) In: Journal of Bone and Mineral Research. 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

48 Citations (Scopus)

343 Downloads (Pure)

Investigation of the Relationship Between Susceptibility Loci for Hip Osteoarthritis and Dual X‐Ray Absorptiometry–Derived Hip Shape in a Population‐Based Cohort of Perimenopausal Women

Baird, D. A., Paternoster, L., Gregory, J. S., Faber, B. G., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Lawlor, D. A., Aspden, R. M. & Tobias, J. H., 27 Oct 2018, (E-pub ahead of print) In: Arthritis and Rheumatology. 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

23 Citations (Scopus)

150 Downloads (Pure)

2017

A smoker with joint pain.

Suarez, A., Faber, B. & Stanton, A., Jul 2017, In: BMJ. 358, j3149.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

DXA-derived hip shape is related to osteoarthritis: findings from in the MrOS cohort

Faber, B. G., Baird, D., Gregson, C. L., Gregory, J. S., Barr, R. J., Aspden, R. M., Lynch, J., Nevitt, M. C., Lane, N. E., Orwoll, E., Tobias, J. H. & Osteoporotic Fractures in Men (MrOS) Study Research Group, Dec 2017, In: Osteoarthritis and Cartilage. 25, 12, p. 2031-2038 8 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

30 Citations (Scopus)

272 Downloads (Pure)

High Bone Mass is associated with bone-forming features of osteoarthritis in non-weight bearing joints independent of body mass index

Gregson, C. L., Hardcastle, S. A., Murphy, A., Faber, B., Fraser, W. D., Williams, M., Davey Smith, G. & Tobias, J. H., Jan 2017, In: Bone. 97, p. 306-313 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

13 Citations (Scopus)

330 Downloads (Pure)

2013

A RARER CASE OF A RARE DISEASE: AGGRESSIVE ANGIOMYXOMA (AAM) IN A SIXTEEN YEAR OLD.

Faber, B., 2013, In: The West London Medical Journal.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Dr Ben G Faber

Research output

Search results