Dr Boris Simonetti

BSc(Trieste), MSc(Paris VII)

  • BS8 1TD

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Mechanisms for endosomal sorting of membrane proteins.

Cells within tissues and organs must efficiently communicate with one another and sense the extracellular environment. This is achieved by the presence of membrane proteins, such as receptors, ion channels and nutrient transporters. To ensure that the membrane proteins are expressed at the correct location, cells have evolved highly organised intracellular sorting pathways, such as the endosomal pathway.
Professor Cullen's group studies the mechanisms of protein sorting by multiprotein complexes that function through the endosomal pathway. My research focus is to understand the molecular basis for protein recycling by endosome-associated SNX-BARs, and its implications in host-pathogen interactions. To achieve these aims, I use biochemical and cellular techniques, including knock-down or knock-out approaches, imaging techniques, together with extensive proteomics.

Fingerprint

Dive into the research topics where Boris Simonetti is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 6 Similar Profiles

Network

Recent external collaboration on country level. Dive into details by clicking on the dots or
If you made any changes in Pure these will be visible here soon.