1985 …2020

Research output per year

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Personal profile

Research interests

The overall aim of work in this laboratory is to understand central nervous system mechanisms of nociception and pain. The focus is on the physiology, anatomy and neurochemistry of descending control systems that originate in the brainstem and that act to co-ordinate changes in motor, autonomic and sensory functions, including pain. These systems underlie the co-ordinated patterns of change in behaviour, nociceptive responsiveness and autonomic outflow that occur: (i) during fever, as part of a sickness response (ii) in different behavioural states, such as fear and anxiety, (iii) in certain pathophysiological conditions, such as stress related disorders and chronic pain.

A better understanding of the neural basis of pain will help develop new strategies for the treatment of chronic pain, such as that which accompanies arthritis.

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Projects

Research Output

  • 50 Article (Academic Journal)
  • 1 Comment/debate (Academic Journal)
  • 1 Special issue (Academic Journal)
  • 1 Review article (Academic Journal)

Cerebellar Modules and Their Role as Operational Cerebellar Processing Units

Apps, R., Hawkes, R., Aoki, S., Bengtsson, F., Brown, A. M., Chen, G., Ebner, T. J., Isope, P., Jörntell, H., Lackey, E. P., Lawrenson, C., Lumb, B., Schonewille, M., Sillitoe, R. V., Spaeth, L., Sugihara, I., Valera, A., Voogd, J., Wylie, D. R. & Ruigrok, T. J. H., 6 Jun 2018, In : Cerebellum. 29 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
  • 19 Citations (Scopus)
    385 Downloads (Pure)

    Correction to: Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paper

    Apps, R., Hawkes, R., Aoki, S., Bengtsson, F., Brown, A. M., Chen, G., Ebner, T. J., Isope, P., Jörntell, H., Lackey, E. P., Lawrenson, C., Lumb, B., Schonewille, M., Sillitoe, R. V., Spaeth, L., Sugihara, I., Valera, A., Voogd, J., Wylie, D. R. & Ruigrok, T. J. H., 21 Jun 2018, (Accepted/In press) In : Cerebellum. p. 1-2 2 p.

    Research output: Contribution to journalComment/debate (Academic Journal)

    3 Citations (Scopus)

    The mystery of the cerebellum: clues from experimental and clinical observations

    Lawrenson, C., Bares, M., Kamondi, A., Kovács, A., Lumb, B., Apps, R., Filip, P. & Manto, M., Dec 2018, In : Cerebellum and Ataxias. 5, 11 p., 8.

    Research output: Contribution to journalReview article (Academic Journal)

    Open Access
    File
  • 11 Citations (Scopus)
    237 Downloads (Pure)

    Activities

    • 1 Participation in workshop, seminar, course

    Early career investigators’ grant funding workshop: The role of the cerebellum in fear circuits.

    Charlotte L Lawrenson (Organiser), , R Apps (Participant), , Bridget Lumb (Participant), & Elena Paci (Participant)

    1 Jul 20182 Jul 2018

    Activity: Participating in or organising an event typesParticipation in workshop, seminar, course

    Supervised Work

    The role of the anterior hypothalamus in the co-ordination of autonomic and sensory functions including pain

    Author: Simpson, D. A. A., 2003

    Supervisor: Lumb, B. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File