Projects per year
The overall aim of work in this laboratory is to understand central nervous system mechanisms of nociception and pain. The focus is on the physiology, anatomy and neurochemistry of descending control systems that originate in the brainstem and that act to co-ordinate changes in motor, autonomic and sensory functions, including pain. These systems underlie the co-ordinated patterns of change in behaviour, nociceptive responsiveness and autonomic outflow that occur: (i) during fever, as part of a sickness response (ii) in different behavioural states, such as fear and anxiety, (iii) in certain pathophysiological conditions, such as stress related disorders and chronic pain.
A better understanding of the neural basis of pain will help develop new strategies for the treatment of chronic pain, such as that which accompanies arthritis.
1/08/20 → 31/07/23
Dynamic contributions of prefrontal-midbrain-spinal cord networks to the development and maintenance of chronic neuropathic pain.
1/01/17 → 31/12/19
Research Output per year
Research output: Contribution to journal › Article (Academic Journal)
Correction to: Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paperApps, R., Hawkes, R., Aoki, S., Bengtsson, F., Brown, A. M., Chen, G., Ebner, T. J., Isope, P., Jörntell, H., Lackey, E. P., Lawrenson, C., Lumb, B., Schonewille, M., Sillitoe, R. V., Spaeth, L., Sugihara, I., Valera, A., Voogd, J., Wylie, D. R. & Ruigrok, T. J. H., 21 Jun 2018, (Accepted/In press) In : Cerebellum. p. 1-2 2 p.
Research output: Contribution to journal › Comment/debate (Academic Journal)
Research output: Contribution to journal › Review article (Academic Journal)
Activities per year
Activity: Participating in or organising an event types › Participation in workshop, seminar, course
The role of the anterior hypothalamus in the co-ordination of autonomic and sensory functions including painAuthor: Simpson, D. A. A., 2003
Supervisor: Lumb, B. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)