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Personal profile

Research interests

We study the role of cancer cell RhoGTPases in CANCER METASTASIS,

with focus on human cancer cell interaction with specific vascular endothelial cells.  

 

Research interests

  • cancer metastasis
  • cancer cell interaction with endothelial cells (blood vessel vasculature)
  • RhoGTPases
  • microfluidics, vasculature on-chip
  • in vitro models 

Research interests

I graduated in medical Biotechnology (BSc) at the University of Milan Bicocca in Italy. At the same university I completed a master’s in science in Pharmacogenomic Biotechnology in 2009 with an ERASMUS final project placement of one year at Complutense University in Madrid, Spain on the anti-tumoral effects of cannabinoids on breast cancer in vitro and in vivo. I completed my PhD in neuro-vascular immunology in 2014 at The Open University in Milton Keynes, UK. My PhD project focused on the role of human brain endothelial microRNA in leukocyte adhesion in neurodegenerative disorder such as multiple sclerosis. In the same year, I joined the Ridley`s Lab at King`s College London as research associate where I investigate the role of RhoGTPases in human breast and prostate cancer cell:endothelial cell interaction and metastasis. I  further developed this project as research associate at Bristol university where Ridley`s lab moved in 2018. 

Structured keywords and research groupings

  • BcompB
  • BLOOD BRAIN BARRIER
  • Rho GTPases
  • Cancer
  • Shear stress
  • flow based assay
  • microRNA
  • cell-cell adhesion
  • Cell migration
  • endothelial cell
  • Cell signalling
  • metastasis

Keywords

  • blood brain barrier
  • cancer metastasis
  • cancer cell:endothelial cells interaction
  • Shear stress
  • Rho GTPases
  • cell adhesion
  • cell migration
  • microRNA
  • Microfabrication
  • live-cell imaging
  • inflammation

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