Dr Camilla Cerutti, PhD, BSc, MSc

  • BS8 1TD

20082019

Research output per year

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Personal profile

Research interests

We study the role of cancer cell RhoGTPases in CANCER METASTASIS,

with focus on human cancer cell interaction with specific vascular endothelial cells.  

 

Research interests

  • cancer metastasis
  • cancer cell interaction with endothelial cells (blood vessel vasculature)
  • RhoGTPases
  • microfluidics, vasculature on-chip
  • in vitro models 

Research interests

I graduated in medical Biotechnology (BSc) at the University of Milan Bicocca in Italy. At the same university I completed a master’s in science in Pharmacogenomic Biotechnology in 2009 with an ERASMUS final project placement of one year at Complutense University in Madrid, Spain on the anti-tumoral effects of cannabinoids on breast cancer in vitro and in vivo. I completed my PhD in neuro-vascular immunology in 2014 at The Open University in Milton Keynes, UK. My PhD project focused on the role of human brain endothelial microRNA in leukocyte adhesion in neurodegenerative disorder such as multiple sclerosis. In the same year, I joined the Ridley`s Lab at King`s College London as research associate where I investigate the role of RhoGTPases in human breast and prostate cancer cell:endothelial cell interaction and metastasis. I  further developed this project as research associate at Bristol university where Ridley`s lab moved in 2018. 

Structured keywords and research groupings

  • BcompB
  • BLOOD BRAIN BARRIER
  • Rho GTPases
  • Cancer
  • Shear stress
  • flow based assay
  • microRNA
  • cell-cell adhesion
  • Cell migration
  • endothelial cell
  • Cell signalling
  • metastasis

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Research Output

  • 7 Article (Academic Journal)
  • 1 Chapter in a book
  • 1 Review article (Academic Journal)

Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/ thromboxane A2

Lucotti, S., Cerutti, C., Soyer, M., Gil-Bernabe, A., Gomes, A., Allen, P., Smart, S., Markelc, B., Watson, K., Armstrong, P., Mitchell, J., Warner, T. D., Ridley, A. J. & Muschel, R. J., 25 Mar 2019, In : Journal of Clinical Investigation. 129, 5, p. 1845-1862 19 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
  • 83 Downloads (Pure)

    Endothelial cell-cell adhesion and signaling

    Cerutti, C. & Ridley, A. J., 1 Sep 2017, In : Experimental Cell Research. 358, 1, p. 31-38 8 p.

    Research output: Contribution to journalReview article (Academic Journal)

    Open Access
    File
  • 295 Downloads (Pure)

    MiR-126 and miR-126* regulate shear-resistant firm leukocyte adhesion to human brain endothelium

    Cerutti, C., Edwards, L. J., de Vries, H. E., Sharrack, B., Male, D. K. & Romero, I. A., 30 Mar 2017, In : Scientific Reports. 7, 14 p., 45284.

    Research output: Contribution to journalArticle (Academic Journal)