Projects per year
Personal profile
Research interests
Throughout my clinical career as a paediatric ophthalmologist at Bristol Eye Hospital and as a researcher, I have been interested in visual development. I have worked with the ALSPAC study for many years and examined the predictors, outcomes and timecourse of different aspects of visual function including refractive error and stereopsis (3D vision). In my clinical role as a Consultant Paediatric Ophthalmologist at Bristol Eye Hospital I have an interest in children with both visual and neurodevelopmental difficulties and I run a specialist clinic for them.
Between 2010-2015 I completed a part-time (60%) NIHR Career Development Fellowship to investigate "Functional Vision" in children with neurodevelopmental difficulties and to design services and treatments to help them. I am now supported by an NIHR Senior Research Fellowship (75% time) to develop and evaluate services for children with cerebral visual impairment (CVI). The programme of research supported by this Fellowship is called the CVI Project.
The CVI Project
Cerebral Visual Impairment (CVI) refers to impairment of vision due to malfunction of the brain, rather than the eyes. CVI is a feature of many neurodevelopmental conditions, affects an estimated 1% of children and results in learning, co-ordination and communication difficulties.
Descriptive studies report that simplifying visual input improves performance in children with CVI but robust data are lacking. CVI is often unrecognised as many affected children have good visual acuity and appear to “see” normally.
The program of work involves refining and evaluating a complex intervention, involving school and hospital components, for children with CVI.
For more information on The CVI Project and my ongoing research in the field of Complex Visual Impairment: www.bristol.ac.uk/ccah/research/childdevelopmentdisability/complex-visual-impairment/
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Collaborations and top research areas from the last five years
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Normative data for retinal nerve fibre layer thickness in children
Williams, C. E. M., Luyt, K., Creavin, A. L., Dubis, A., Guggenheim, J. A. & Atan, D.
Project: Research
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Research output
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Assessing the contribution of genetic nurture to refractive error
UK Biobank Eye and Vision Consortium, 1 Nov 2022, In: European Journal of Human Genetics. 30, 11, p. 1226-1232 7 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)8 Downloads (Pure) -
Clinical assessment, investigation, diagnosis and initial management of cerebral visual impairment: a consensus practice guide
Pilling, R. F., Allen, L., Bowman, R., Ravenscroft, J., Saunders, K. J. & Williams, C., 18 Oct 2022, (E-pub ahead of print) In: Eye. 8 p.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open AccessFile4 Citations (Scopus)18 Downloads (Pure) -
Effectiveness of early spectacle intervention on visual outcomes in babies at risk of cerebral visual impairment: a parallel group, open-label, randomised clinical feasibility trial protocol
Bullaj, R., Dyet, L., Mitra, S., Bunce, C., Clarke, C. S., Saunders, K., Dale, N., Horwood, A., Williams, C., St Clair Tracy, H., Marlow, N. & Bowman, R., 21 Sept 2022, In: BMJ Open. 12, 9, e059946.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)10 Downloads (Pure)