Projects per year
Personal profile
Research interests
Throughout my clinical career as a paediatric ophthalmologist at Bristol Eye Hospital and as a researcher, I have been interested in visual development. I have worked with the ALSPAC study for many years and examined the predictors, outcomes and timecourse of different aspects of visual function including refractive error and stereopsis (3D vision). In my clinical role as a Consultant Paediatric Ophthalmologist at Bristol Eye Hospital I have an interest in children with both visual and neurodevelopmental difficulties and I run a specialist clinic for them.
Between 2010-2015 I completed a part-time (60%) NIHR Career Development Fellowship to investigate "Functional Vision" in children with neurodevelopmental difficulties and to design services and treatments to help them. I am now supported by an NIHR Senior Research Fellowship (75% time) to develop and evaluate services for children with cerebral visual impairment (CVI). The programme of research supported by this Fellowship is called the CVI Project.
The CVI Project
Cerebral Visual Impairment (CVI) refers to impairment of vision due to malfunction of the brain, rather than the eyes. CVI is a feature of many neurodevelopmental conditions, affects an estimated 1% of children and results in learning, co-ordination and communication difficulties.
Descriptive studies report that simplifying visual input improves performance in children with CVI but robust data are lacking. CVI is often unrecognised as many affected children have good visual acuity and appear to “see” normally.
The program of work involves refining and evaluating a complex intervention, involving school and hospital components, for children with CVI.
For more information on The CVI Project and my ongoing research in the field of Complex Visual Impairment: www.bristol.ac.uk/ccah/research/childdevelopmentdisability/complex-visual-impairment/
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Collaborations and top research areas from the last five years
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Normative data for retinal nerve fibre layer thickness in children
Williams, C. E. M. (Principal Investigator), Luyt, K. (Co-Principal Investigator), Creavin, A. L. (Co-Principal Investigator), Dubis, A. (Co-Principal Investigator), Guggenheim, J. A. (Co-Principal Investigator) & Atan, D. (Co-Principal Investigator)
Project: Research
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Two months of Dr Rosie Clark
Williams, C. E. M. (Principal Investigator)
1/07/17 → 31/08/17
Project: Research
Research output
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Estimating the true effect of lifestyle risk factors for myopia: A longitudinal study of UK children
Guggenheim, J. A., Clark, R., Pease, A. S., Blair, P. S. & Williams, C. E. M., 10 Oct 2024, (Accepted/In press) In: Translational Vision Science and Technology.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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A new polygenic score for refractive error improves detection of children at risk of high myopia but not the prediction of those at risk of myopic macular degeneration
The CREAM Consortium, 1 May 2023, In: EBioMedicine. 91, 104551.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access5 Citations (Scopus) -
Quality of Life at a 10-Year Follow-Up of Children Born Preterm with Post-Hemorrhagic Ventricular Dilatation: A Cohort Study
Rela, A., Jary, S., Williams, C., Blair, P., Hollingworth, W., Pople, I., Whitelaw, A., Luyt, K. & Odd, D. E., 1 Nov 2023, In: Neonatology. 120, 6, p. 690-698 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access