Projects per year
Natural products isolated from bacteria, fungi and plants from both marine and terrestrial environments are a rich source of compounds of medicinal and agrochemical importance. We have published >130 papers which centre upon:-
- Structure elucidation and total synthesis of natural products
- Design and synthesis of probes to elucidate biosynthetic pathways and enzyme mechanisms
- Enantioselective synthesis of amino acids and heterocycles
- Isotopic labelling, biotransformations and reaction mechanisms
Professor Willis is a supervisor in the EPSRC Centre for Doctoral Training in Chemical Synthesis
1/10/19 → 30/09/22
31/07/14 → 30/09/21
A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Spongeet al., 11 Feb 2021, In: Marine Drugs. 19, 2, 19 p., 105.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile22 Downloads (Pure)
Cleaning the Cellular Factory: Deletion of McrA in Aspergillus oryzae NSAR1 and the generation of a novel kojic acid deficient strain for cleaner heterologous production of secondary metabolitesDao, T. T., De Mattos-Shipley, K. M., Prosser, I. M., Williams, K., Zacharova, M. K., Lazarus, C. M., Willis, C. L. & Bailey, A. M., 9 Feb 2021, In: Frontiers in Fungal Biology. 2, 632542, 12 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile5 Downloads (Pure)
Willis, C. L., 16 Mar 2020, (E-pub ahead of print) In: Organic Letters. 5 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile11 Downloads (Pure)