Projects per year
Personal profile
Research interests
Natural products isolated from bacteria, fungi and plants from both marine and terrestrial environments are a rich source of compounds of medicinal and agrochemical importance. We have published >130 papers which centre upon:-
- Structure elucidation and total synthesis of natural products
- Design and synthesis of probes to elucidate biosynthetic pathways and enzyme mechanisms
- Enantioselective synthesis of amino acids and heterocycles
- Isotopic labelling, biotransformations and reaction mechanisms
Professor Willis is a supervisor in the EPSRC Centre for Doctoral Training in Chemical Synthesis
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Projects
- 9 Finished
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Structural and Mechanistic Investigations of Antibiotic Production in Bacteria
1/08/18 → 1/08/18
Project: Research, Parent
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Research output
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Biosynthesis of pleuromutilin congeners using an Aspergillus oryzae expression platform
Alberti, F., Khairudin, K., Davies, J., Sangmalee, S., Willis, C. L., Foster, G. D. & Bailey, A. M., 15 Mar 2023, In: Chemical Science. 14, 14, p. 3826-3833 8 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access -
Correction: Back et al. A New Micromonospora Strain with Antibiotic Activity Isolated from the Microbiome of a Mid-Atlantic Deep-Sea Sponge. Mar. Drugs 2021, 19, 105
Back, C. R., Stennett, H. L., Williams, S. E., Wang, L., Gomez, J. O., Abdulle, O. M., Duffy, T., Neal, C., Mantell, J., Jepson, M. A., Hendry, K. R., Powell, D., Stach, J. E. M., Essex-Lopresti, A. E., Willis, C. L., Curnow, P. & Race, P. R., 28 Mar 2023, In: Marine Drugs. 21, 4, 214.Research output: Contribution to journal › Article (Academic Journal)
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Cladobotric acids: Metabolites from cultures of Cladobotryum sp., semi-synthetic analogues and antibacterial activity
Dao, T. T., Williams, K., de Mattos-Shipley, K. M. J., Song, Z., Takebayashi, Y., Simpson, T. J., Spencer, J., Bailey, A. M. & Willis, C. L., 16 Feb 2022, In: Journal of Natural Products. 85, 3, p. 572-580 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile2 Citations (Scopus)45 Downloads (Pure)