Projects per year
Natural products isolated from bacteria, fungi and plants from both marine and terrestrial environments are a rich source of compounds of medicinal and agrochemical importance. We have published >130 papers which centre upon:-
- Structure elucidation and total synthesis of natural products
- Design and synthesis of probes to elucidate biosynthetic pathways and enzyme mechanisms
- Enantioselective synthesis of amino acids and heterocycles
- Isotopic labelling, biotransformations and reaction mechanisms
Professor Willis is a supervisor in the EPSRC Centre for Doctoral Training in Chemical Synthesis
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1/10/19 → 30/09/22
1/08/18 → 1/08/18
Project: Research, Parent
Cladobotric acids: Metabolites from cultures of Cladobotryum sp., semi-synthetic analogues and antibacterial activityDao, T. T., Williams, K., de Mattos-Shipley, K. M. J., Song, Z., Takebayashi, Y., Simpson, T. J., Spencer, J., Bailey, A. M. & Willis, C. L., 16 Feb 2022, In: Journal of Natural Products. 85, 3, p. 572-580 9 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile
Williams, K., de Mattos-Shipley, K. M. J., Willis, C. L. & Bailey, A. M., 17 Feb 2022, In: Fungal Biology and Biotechnology. 9, 1, 21 p., 2.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile13 Downloads (Pure)
Synthetic and Biosynthetic Methods for Selective Cyclisations of 4,5-Epoxy Alcohols to TetrahydropyransBowen, J. I., Wang, L., Crump, M. P. & Willis, C. L., 14 Jan 2022, In: Organic and Biomolecular Chemistry. 20, 6, p. 1150-1175 26 p., 20.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile1 Downloads (Pure)