Professor Chris L Willis

B.Sc.(Lond.), D.Phil.(Sus.)

  • BS8 1TS

1991 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Natural products isolated from bacteria, fungi and plants from both marine and terrestrial environments are a rich source of compounds of medicinal and agrochemical importance. We have published >130 papers which centre upon:-

  • Structure elucidation and total synthesis of natural products
  • Design and synthesis of probes to elucidate biosynthetic pathways and enzyme mechanisms
  • Enantioselective synthesis of amino acids and heterocycles
  • Isotopic labelling, biotransformations and reaction mechanisms

Professor Willis is a supervisor in the EPSRC Centre for Doctoral Training in Chemical Synthesis

Fingerprint Dive into the research topics where Chris L Willis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 8 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects

Research Output

A Bioinspired Strategy for the Enantioselective Synthesis of Bicyclic Oxygen Heterocycles

Rodriguez Venegas, E. & Willis, C. L., 16 Mar 2020, In : Organic Letters. 5 p.

Research output: Contribution to journalArticle (Academic Journal)

  • ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer’s disease

    Evans, C., Miners, J. S., Piva, G., Willis, C. L., Heard, D. M., Kidd, E. J., Good, M. & Kehoe, P. G., 25 Jan 2020, In : Acta Neuropathologica. 18 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 44 Downloads (Pure)

    A Priming Cassette Generates Hydroxylated Acyl Starter Units in Mupirocin and Thiomarinol Biosynthesis

    Walker, P. D., Rowe, M. T., Winter, A. J., Weir, A. N. M., Akter, N., Wang, L., Race, P. R., Williams, C., Song, Z., Simpson, T. J., Willis, C. L. & Crump, M. P., 6 Feb 2020, In : ACS Chemical Biology. 2020, 10 p.

    Research output: Contribution to journalArticle (Academic Journal)

  • Supervised Work

    Lithiation—Borylation Methodology: Applications in the Synthesis of Polypropionate Fragment and Polyfluoromethylation Reactions of Organoboronic Esters

    Author: Zhou, B., 7 May 2019

    Supervisor: Aggarwal, V. (Supervisor) & Willis, C. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Maleidride Natural Products: Structural and Synthetic Studies

    Author: Heard, D., 25 Jun 2019

    Supervisor: Cox, R. (Supervisor) & Willis, C. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Mechanisms for the Generation of Structural Diversity in Polyketide Biosynthesis

    Author: Walker, P., 7 May 2019

    Supervisor: Willis, C. (Supervisor), Race, P. (Supervisor) & Crump, M. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File