Projects per year
Our group's research focuses on the regulation of cartilage and bone homeostasis in development and in disease states such as osteoarthritis, osteoporosis and Stickler syndrome as well as during repair and regeneration. We are particularly interested in the interplay between genes and environmental cues such as mechanical loading, diet, and metabolism. We use the zebrafish as a model because it combines excellent genetics with beautiful imaging possibilities, which allow us to study the development of the skeletal system dynamically in vivo.
We have a number of projects running in collaboration with clinicians, engineers and epidemiologists.
Additionally, with Emma Vincent, I colead an Elizabeth Blackwell Institute research strand called 'Mechanisms to Populations' which aims to help overcome the barriers to interdisciplinary work in epidmiology and functional biological studies. For mroe information on the strand please see:
- 1 Similar Profiles
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Form, function and development of the amniote skull: a case study using lepidosaurs
1/04/22 → 31/03/25
8051 sLOLA - BB/T001984/1 - Via Manchester
1/01/20 → 31/12/24
BBSRC ALERT 21 LCM-MM: Bringing Laser Capture Microscopy Technology to the University of Bristol
1/03/22 → 28/02/23
Autophagy tunes chondrocyte differentiation and joint developmental precision in zebrafishMoss, J. J., Wirth, M., Tooze, S. A., Hammond, C. & Lane, J. D., 1 Jul 2022, In: Autophagy Reports.
Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Growth orientations, rather than heterogeneous growth rates, dominate jaw joint morphogenesis in the larval zebrafishGodivier, J. M., Lawrence, L., Wang, M., Hammond, C. & Nowlan, N., 5 May 2022, In: Journal of Anatomy. 241, 2, p. 358-371 14 p.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile15 Downloads (Pure)
Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal diseaseBergen, D. J. M., Tong, Q., Shukla, A., Newham, E., Zethof, J., Lundberg, M., Ryan, R., Youlten, S. E., Frysz, M., Croucher, P. I., Flik, G., Richardson, R. J., Kemp, J. P., Hammond, C. L. & Metz, J. R., 21 Jan 2022, In: BMC Biology. 20, 1, 25 p., 21.
Research output: Contribution to journal › Article (Academic Journal) › peer-reviewOpen AccessFile6 Citations (Scopus)40 Downloads (Pure)
Data from Wnt and joint mechanics (07-2017)
Hammond, C. L. (Creator), University of Bristol, 4 Jul 2017
DOI: 10.5523/bris.3mda1vet7c7wu298pms51n9j1p, http://data.bris.ac.uk/data/dataset/3mda1vet7c7wu298pms51n9j1p
Zebrafish Spine FE data
Hammond, C. L. (Creator), University of Bristol, 5 Nov 2019
DOI: 10.5523/bris.2g8lgn2wtynw22v8cm913p80qe, http://data.bris.ac.uk/data/dataset/2g8lgn2wtynw22v8cm913p80qe
- 1 Schools engagement
Authentic Biology at Cotham School
Chrissy L Hammond (Organiser)Nov 2012 → Dec 2015
Activity: Talk or presentation types › Schools engagement