Christiane H Berger-Schaffitzel

2025

Allosteric modulation by the fatty acid site in the glycosylated SARS-CoV-2 spike

Oliveira, A. S. F., Kearns, F. L., Rosenfeld, M. A., Casalino, L., Tulli, L., Berger, I., Schaffitzel, C., Davidson, A. D., Amaro, R. E. & Mulholland, A. J., 10 Apr 2025, In: eLife. 13, 22 p., RP97313.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2

Szeto, J.-Y., Vivoli Vega, M., Mailliot, J. M., Orriss, G. L., Sun, L., Bufton, J. C., Powers, K. T., Yadav Kadapalakere, S., Berger, I. & Schaffitzel, C., 20 Mar 2025, (Accepted/In press) In: RNA.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

2024

An engineered baculoviral protein and DNA co-delivery system for CRISPR-based mammalian genome editing

Capin, J., Harrison, A., Raele, R. A., Yadav, S. K. N., Baiwir, D., Mazzucchelli, G., Quinton, L., Satchwell, T. J., Toye, A. M., Schaffitzel, C., Berger, I. & Aulicino, F., 12 Apr 2024, In: Nucleic Acids Research. 52, 6, p. 3450-3468 19 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

4 Citations (Scopus)

Engineering the ADDobody protein scaffold for generation of high-avidity ADDomer super-binders

Buzas, D., Sun, H., Toelzer, C., Yadav, S. K. N., Borucu, U., Gautam, G., Gupta, K., Bufton, J. C., Capin, J. M., Sessions, R. B., Garzoni, F., Berger, I. & Berger-Schaffitzel, C. H., 9 Jan 2024, In: Structure. 32, 3, p. 342-351.e6

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

Sample Preparation for Electron Cryo-Microscopy of Macromolecular Machines

Deniaud, A., Kabasakal, B. V., Bufton, J. C. & Schaffitzel, C., 21 Mar 2024, (E-pub ahead of print) Advanced Technologies for Protein Complex Production and Characterization . Vega, M. C. & Fernandez, F. J. (eds.). Springer, Cham, Vol. 2. p. 173-190 18 p. (Advances in Experimental Medicine and Biology; vol. 3234).

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Open Access

File

1 Citation (Scopus)

Tuning VSV-G Expression Improves Baculovirus Integrity, Stability and Mammalian Cell Transduction Efficiency

Mattioli, M., Raele, R. A., Gautam, G., Borucu, U., Schaffitzel, C., Aulicino, F. & Berger, I., 17 Sept 2024, In: Viruses. 16, 9, 17 p., 1475.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2023

ADDovenom: Thermostable Protein-Based ADDomer Nanoparticles as New Therapeutics for Snakebite Envenoming

Menzies, S. K., Arinto-Garcia, R., Amorim, F. G., Cardoso, I. A., Abada, C., Crasset, T., Durbesson, F., Edge, R. J., El-Kazzi, P., Hall, S., Redureau, D., Stenner, R., Boldrini-França, J., Sun, H., Roldão, A., Alves, P. M., Harrison, R. A., Vincentelli, R., Berger, I. & Quinton, L. & 2 others, Casewell, N. R. & Schaffitzel, C., 28 Nov 2023, In: Toxins. 15, 12, 673.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

1 Citation (Scopus)

An expandable, modular de novo protein platform for precision redox engineering

Hutchins, G. H., Noble, C. E. M., Bunzel, H. A., Williams, C., Dubiel, P., Yadav, S. K. N., Molinaro, P. M., Barringer, R., Blackburn, H., Hardy, B. J., Parnell, A. E., Landau, C., Race, P. R., Oliver, T. A. A., Koder, R. L., Crump, M. P., Schaffitzel, C., Oliveira, A. S. F., Mulholland, A. J. & Anderson, J. L. R., 1 Aug 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 31, e2306046120.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

11 Citations (Scopus)

Antibodies generated<i>in vitro</i>and<i>in vivo</i>elucidate design of a thermostable ADDomer COVID-19 nasal nanoparticle vaccine

Buzas, D., Bunzel, H. A., Staufer, O., Milodowski, E., Edmonds, G., Bufton, J., Vidana, B., Yadav, S., Gupta, K., Fletcher, C., Williamson, M. K., Harrison, A., Borucu, U., Capin, J., Francis, O., Balchin, G., Hall, S., Vega, M. V., Fabien, D. & Vincentelli, R. & 16 others, Roe, J., Wooldridge, L., Burt, R., Anderson, R., Mulholland, A., Hare, J., Bailey, M., Davidson, A., Finn, A., Morgan, D., Mann, J., Spatz, J., Garzoni, F., Berger-Schaffitzel, C. H., Berger, I. & Group, B. U., 17 Mar 2023

Research output: Other contribution

Cryo-EM reveals binding of linoleic acid to SARS-CoV-2 spike glycoprotein, suggesting an antiviral treatment strategy

Toelzer, C., Gupta, K., Berger, I. & Berger-Schaffitzel, C. H., 1 Feb 2023, In: Acta Crystallographica Section D: Structural Biology. 79, 2, p. 111-121 11 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

10 Citations (Scopus)

In vitro generated antibodies guide thermostable ADDomer nanoparticle design for nasal vaccination and passive immunization against SARS-CoV-2

Buzas, D., Bunzel, A. H., Staufer, O., Milodowski, E. J., Edmunds, G. L., Bufton, J. C., Vidana mateo, B. V., Yadav, S. K. N., Gupta, K., Fletcher, C., Williamson, M. K., Harrison, A., Borucu, U., Capin, J., Francis, O., Balchin, G., Hall, S., Vega, M. V., Durbesson, F. & Lingappa, S. & 17 others, Vincentelli, R., Roe, J., Wooldridge, L., Burt, R., Anderson, R. J. L., Mulholland, A. J., Bristol uncover group, W. M. P. H. D., Hare, J., Bailey, M., Davidson, A. D., Finn, A., Morgan, D., Mann, J., Spatz, J., Garzoni, F., Schaffitzel, C. & Berger, I., 17 Oct 2023, In: Antibody Therapeutics. 6, 4, p. 277-297

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

2 Citations (Scopus)

Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD

Basu, S., Berger, I., Berger-Schaffitzel, C. H., Klenerman, D., Hendrich, B. D., Holcman, D., Laue, E. D. & al, E., 1 Nov 2023, In: Nature structural & molecular biology. 30, 11, p. 1628-1639 12 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

9 Citations (Scopus)

Nonsense-Mediated mRNA Decay Factor Functions in Human Health and Disease

Sun, L., Mailliot, J. M. & Berger-Schaffitzel, C. H., 27 Feb 2023, In: Biomedicines. 11, 3, 722.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

12 Citations (Scopus)

SARS-CoV-2 spike variants differ in their allosteric responses to linoleic acid

Oliveira, A. S. F., Shoemark, D. K., Davidson, A. D., Berger, I., Schaffitzel, C. & Mulholland, A. J., 29 Mar 2023, In: Journal of molecular cell biology. 15, 3, 12 p., mjad021.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

5 Citations (Scopus)

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome

Healy, M. D., McNally, K. E., Butkovič, R., Chilton, M., Kato, K., Sacharz, J., McConville, C., Moody, E. R. R., Shaw, S., Planelles-Herrero, V. J., Yadav, S. K. N., Ross, J., Borucu, U., Palmer, C. S., Chen, K.-E., Croll, T. I., Hall, R. J., Caruana, N. J., Ghai, R. & Nguyen, T. H. D. & 9 others, Heesom, K. J., Saitoh, S., Berger, I., Schaffitzel, C., Williams, T. A., Stroud, D. A., Derivery, E., Collins, B. M. & Cullen, P. J., 11 May 2023, In: Cell. 186, 10, p. 2219-2237.e29 49 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

25 Citations (Scopus)

2022

Highly efficient CRISPR-mediated large DNA docking and multiplexed prime editing using a single baculovirus

Aulicino, F., Pelosse, M., Toelzer, C., Capin, J. M., Meysami, P., Dillingham, M. S., Berger-Schaffitzel, C. H., Saleem, M., Welsh, G. I., Berger, I. & et, A., 8 Jul 2022, (E-pub ahead of print) In: Nucleic Acids Research. 50, 13, p. 7783–7799 17 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

28 Citations (Scopus)

141 Downloads (Pure)

Molecular architecture of the autoinhibited kinesin-1 lambda particle

Weijman, J. F. M. S., Yadav Kadapalakere, S., Surridge, K. J., Cross, J. A. A., Mantell, J. M., Woolfson, D. N., Berger-Schaffitzel, C. H. & Dodding, M. P., 16 Sept 2022, In: Science Advances.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

11 Citations (Scopus)

Molecular dynamics of spike variants in the locked conformation: RBD interfaces, fatty acid binding and furin cleavage sites

Shoemark, D. K., Oliveira, A. S. F., Davidson, A. D., Berger, I., Schaffitzel, C. & Mulholland, A. J., 8 May 2022

Research output: Other contribution

No-nonsense: insights into the functional interplay of nonsense-mediated mRNA decay factors

Mailliot, J. M., Vivoli Vega, M. & Berger-Schaffitzel, C. H., 12 May 2022, In: Biochemical Journal. 479, 9, p. 973-993 21 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

13 Citations (Scopus)

94 Downloads (Pure)

Pathogen-sugar interactions revealed by universal saturation transfer analysis

Berger-Schaffitzel, C. H. & Berger, I., 23 Jun 2022, In: Science. 377, 6604

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

30 Citations (Scopus)

401 Downloads (Pure)

Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2

Gupta, K., Toelzer, C., Kavanagh Williamson, M., Shoemark, D. K., Oliveira, A., Davidson, A. D., Almuqrin, A. M., Staufer, O., Yadav Kadapalakere, S., Borucu, U., Garzoni, F., Fitzgerald, D. J., Spatz, J. P., Mulholland, A. J., Davidson, A. D., Berger-Schaffitzel, C. H. & Berger, I., 11 Jan 2022, In: Nature Communications. 13, 1, 12 p., 222.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

17 Citations (Scopus)

136 Downloads (Pure)

Structures of nonsense-mediated mRNA decay factors UPF3B and UPF3A in complex with UPF2 reveal molecular basis for competitive binding and for neurodevelopmental disorder-causing mutation.

Bufton, J. C., Powers, K. T., Toelzer, C., Berger, I., Berger-Schaffitzel, C. H. & Szeto, A., 31 May 2022, In: Nucleic Acids Research. 50, 10, p. 5934-5947 14 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

11 Citations (Scopus)

98 Downloads (Pure)

Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein

Staufer, O., Gupta, K., Singh, G., Vasileiou, K., Berger-Schaffitzel, C. H., Platzman, I., Berger, I. & Spatz, J. P., 14 Feb 2022, (E-pub ahead of print) In: Nature Communications. 13, 1, 868 .

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

25 Citations (Scopus)

135 Downloads (Pure)

The Free Fatty Acid-Binding Pocket is a Conserved Hallmark in Pathogenic β-Coronavirus Spike Proteins from SARS-CoV to Omicron

Toelzer, C., Gupta, K., Yadav Kadapalakere, S., Hodgson, L. R., Kavanagh Williamson, M., Buzas, D., Borucu, U., Powers, K. T., Stenner, R. A., Vasileiou, K., Garzoni, F., Fitzgerald, D. J., Payré, C., Gautam, G., Lambeau, G., Davidson, A. D., Verkade, P., Martin, F., Berger, I. & Berger-Schaffitzel, C. H., 25 Nov 2022, In: Science Advances. 8, 47, 12 p., eadc9179.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

27 Citations (Scopus)

106 Downloads (Pure)

2021

Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA

Powers, K. T., Stevenson-Jones, F. R., Yadav Kadapalakere, S., Bufton, J. C., Borucu, U., Shen, D. & Berger-Schaffitzel, C. H., 21 Jul 2021, In: Nucleic Acids Research. 49, 13, p. 7665-7679 15 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

12 Citations (Scopus)

142 Downloads (Pure)

Frontispiz: Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS-CoV-2 Spike Protein

Shoemark, D. K., Colenso, C. K., Toelzer, C., Gupta, K., Sessions, R. B., Davidson, A. D., Berger, I., Schaffitzel, C., Spencer, J. & Mulholland, A. J., 22 Mar 2021, In: Angewandte Chemie. 133, 13

Research output: Contribution to journal › Comment/debate (Academic Journal)

Identification and Phenotypic Characterization of Hsp90 Phosphorylation Sites That Modulate Virulence Traits in the Major Human Fungal Pathogen Candida albicans

Alaalm, L., Crunden, J. L., Butcher, M., Obst, U., Whealy, R., Williamson, C., O'Brien, H., Berger-Schaffitzel, C. H., Ramage, G., Spencer, J. & Diezmann, S., 27 Aug 2021, In: Frontiers in Cellular and Infection Microbiology. 11, 637836.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

8 Citations (Scopus)

91 Downloads (Pure)

Molecular Simulations suggest Vitamins, Retinoids and Steroids as Ligands of the Free Fatty Acid Pocket of the SARS-CoV-2 Spike Protein*

Shoemark, D. K., Colenso, C. K., Toelzer, C., Gupta, K., Sessions, R. B., Sessions, R. B., Davidson, A. D., Berger, I., Schaffitzel, C., Spencer, J. & Mulholland, A. J., 22 Mar 2021, In: Angewandte Chemie. 60, 13, 13 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

71 Citations (Scopus)

399 Downloads (Pure)

Structural biology in the fight against COVID-19

Berger-Schaffitzel, C. H. & et al., 12 Jan 2021, In: Nature Structural and Molecular Biology. 28, 1, p. 2–7 6 p.

Research output: Contribution to journal › Article (Academic Journal)

Open Access

File

20 Citations (Scopus)

87 Downloads (Pure)

The fatty acid site is coupled to functional motifs in the SARS-CoV-2 spike protein and modulates spike allosteric behaviour

Oliveira, A., Shoemark, D. K., Avila Ibarra, A., Davidson, A. D., Berger, I., Berger-Schaffitzel, C. H. & Mulholland, A. J., 11 Dec 2021, In: Computational and Structural Biotechnology Journal. 20, p. 139-147 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

101 Downloads (Pure)

VLP-factory™ and ADDomer ^©: Self-assembling Virus-Like Particle (VLP) technologies for multiple protein and peptide epitope display

Sari-Ak, D., Bufton, J. C., Gupta, K., Garzoni, F., Fitzgerald, D. J., Berger-Schaffitzel, C. H. & Berger, I., 17 Mar 2021, In: Current Protocols. 1, 3, 25 p., e55.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

9 Citations (Scopus)

481 Downloads (Pure)

2020

Baculovirus-vectored precision delivery of large DNA cargoes in human genomes

Aulicino, F., Pelosse, M., Toelzer, C., Capin, J., Meysami, P., Dillingham, M. S., Schaffitzel, C. & Berger, I., 17 Aug 2020

Research output: Other contribution

Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein

Toelzer, C., Gupta, K., Yadav, S. K. N., Borucu, U., Davidson, A. D., Kavanagh Williamson, M., Shoemark, D. K., Garzoni, F., Staufer, O., Milligan, R., Capin, J., Mulholland, A. J., Berger, I. & Schaffitzel, C., 6 Nov 2020, In: Science. 370, 6517, 12 p., eabd3255.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

300 Citations (Scopus)

323 Downloads (Pure)

New insights into no-go, non-stop and nonsense-mediated mRNA decay complexes

Powers, K. T., Szeto, A. & Berger-Schaffitzel, C. H., 1 Dec 2020, In: Current Opinion in Structural Biology. 65, p. 110-118 9 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

47 Citations (Scopus)

382 Downloads (Pure)

Precision design of single and multi-heme de novo proteins

Hutchins, G. H., Noble, C. E. M., Hardy, B., Parnell, A. E., Yadav Kadapalakere, S., Williams, C., Race, P. R., Oliveira, S., Crump, M. P., Berger-Schaffitzel, C. H., Mulholland, A. J. & Anderson, J. L. R., 24 Sept 2020, (Unpublished) In: bioRxiv.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

File

161 Downloads (Pure)

Production of Multi-subunit Membrane Protein Complexes

Kabasakal, B. V., Jiang, Q. & Berger-Schaffitzel, C. H., 11 Dec 2020, Multiprotein Complexes : Methods and Protocols. Poterszman, A. (ed.). 1 ed. Springer US, Vol. 2247. p. 3-16

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Open Access

File

145 Downloads (Pure)

The SARS-CoV-2 spike protein: balancing stability and infectivity

Berger, I. & Schaffitzel, C., 2 Nov 2020, In: Cell Research. 2020, 2 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

69 Citations (Scopus)

97 Downloads (Pure)

2019

Cloning, Expression and Purification of Intact Polyketide Synthase Modules

Maschio, L., Parnell, A., Lees, N. R., Willis, C., Berger-Schaffitzel, C., Stach, J. E. M. & Race, P., 4 Feb 2019, (E-pub ahead of print) Methods in Enzymology: Metabolons and Supramolecular Enzyme Assemblies. Elsevier Inc., Vol. 617. p. 63-82 20 p. (Methods in Enzymology).

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

5 Citations (Scopus)

High-Throughput Production of Influenza Virus-Like Particle (VLP) Array by Using VLP-factory™, a MultiBac Baculoviral Genome Customized for Enveloped VLP Expression

Sari-Ak, D., Bahrami, S., Laska, M., Drncova, P., Fitzgerald, D. J., Berger-Schaffitzel, C., Garzoni, F. & Berger, I., 3 Jul 2019, (E-pub ahead of print) High-Throughput Protein Production and Purification: Methods and Protocols. Vincentelli, R. (ed.). Humana Press, p. 213-226 14 p. (Methods in Molecular Biology; vol. 2025).

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Open Access

File

9 Citations (Scopus)

143 Downloads (Pure)

MultiBac: Baculovirus-Mediated Multigene DNA Cargo Delivery in Insect and Mammalian Cells

Gupta, K., Toelzer, C., Sari-Ak, D., Fitzgerald, D. J., Berger-Schaffitzel, C. & Berger, I., Mar 2019, In: Viruses. 11, 3, 14 p., 198.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

34 Citations (Scopus)

454 Downloads (Pure)

Structure and Dynamics of the Central Lipid Pool and Proteins of the Bacterial Holo-Translocon

Martin, R., Larsen, A. H., Corey, R. A., Midtgaard, S. R., Frielinghaus, H., Schaffitzel, C., Arleth, L. & Collinson, I., 21 May 2019, In: Biophysical Journal. 116, 10, p. 1931-1940 10 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

16 Citations (Scopus)

338 Downloads (Pure)

Synthetic self-assembling ADDomer platform for highly efficient vaccination by genetically encoded multiepitope display

Vragniau, C., Bufton, J. C., Garzoni, F., Stermann, E., Rabi, F., Terrat, C., Guidetti, M., Josserand, V., Williams, M., Woods, C. J., Viedma, G., Bates, P., Verrier, B., Chaperot, L., Schaffitzel, C., Berger, I. & Fender, P., 25 Sept 2019, In: Science Advances. 5, 9, 9 p., eaaw2853.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

28 Citations (Scopus)

280 Downloads (Pure)

2018

Efficient production of a mature and functional gamma secretase protease

Khan, I., Krishnaswamy, S., Sabale, M., Groth, D., Wijaya, L., Morici, M., Berger, I., Schaffitzel, C., Fraser, P. E., Martins, R. N. & Verdile, G., 27 Aug 2018, In: Scientific Reports. 8, 15 p., 12834.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

4 Citations (Scopus)

344 Downloads (Pure)

New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors

Raimondeau, E., Bufton, J. C. & Schaffitzel, C., 19 Jun 2018, In: Biochemical Society Transactions. 46, 3, p. 503-512 10 p., BST20170427.

Research output: Contribution to journal › Review article (Academic Journal) › peer-review

Open Access

File

32 Citations (Scopus)

411 Downloads (Pure)

Structure of a human cap-dependent 48S translation pre-initiation complex

Eliseev, B., Yeramala, L., Leitner, A., Karuppasamy, M., Raimondeau, E., Huard, K., Alkalaeva, E., Aebersold, R. & Schaffitzel, C., 16 Mar 2018, In: Nucleic Acids Research. 46, 5, p. 2678-2689 12 p., gky054.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

55 Citations (Scopus)

316 Downloads (Pure)

2017

Cryo-EM Structure of Saccharomyces cerevisiae Target of Rapamycin Complex 2

Karuppasamy, M., Kusmider, B., Oliveira, T. M., Gaubitz, C., Prouteau, M., Loewith, R. & Schaffitzel, C., 23 Nov 2017, In: Nature Communications. 8, 18 p., 1729.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

47 Citations (Scopus)

594 Downloads (Pure)

Dual function of UPF3B in early and late translation termination

Neu-Yilik, G., Raimondeau, E., Eliseev, B., Yeramala, L., Amthor, B., Deniaud, A., Huard, K., Kerschgens, K., Hentze, M. W., Schaffitzel, C. & Kulozik, A. E., 16 Oct 2017, In: EMBO Journal. 36, 20, p. 2968-2986 19 p.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

74 Citations (Scopus)

316 Downloads (Pure)

Multiprotein complex production in E. coli: the SecYEG-SecDFYajC-YidC Holotranslocon

Berger, I., Jiang, Q., Schulze, R., Collinson, I. & Schaffitzel, C., 2017, Heterologous Gene Expression in E.coli: Methods and Protocols. Burgess-Brown, N. A. (ed.). Springer, p. 279-290 12 p. (Methods in Molecular Biology; vol. 1586).

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Open Access

File

1 Citation (Scopus)

468 Downloads (Pure)

2016

ACEMBL Tool-Kits for High-Throughput Multigene Delivery and Expression in Prokaryotic and Eukaryotic Hosts

Nie, Y., Chaillet, M., Becke, C., Haffke, M., Pelosse, M., Fitzgerald, D., Collinson, I., Schaffitzel, C. & Berger, I., 11 May 2016, Advanced Technologies for Protein Complex Production and Characterization. Vega, M. C. (ed.). Springer International Publishing AG, p. 27-42 16 p. (Advances in Experimental Medicine and Biology; vol. 896).

Research output: Chapter in Book/Report/Conference proceeding › Chapter in a book

Open Access

File

18 Citations (Scopus)

624 Downloads (Pure)

A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion

Botte, M., Zaccai, N. R., Nijeholt, J. L. À., Martin, R., Knoops, K., Papai, G., Zou, J., Deniaud, A., Karuppasamy, M., Jiang, Q., Roy, A. S., Schulten, K., Schultz, P., Rappsilber, J., Zaccai, G., Berger, I., Collinson, I. & Schaffitzel, C., 7 Dec 2016, In: Scientific Reports. 6, 13 p., 38399.

Research output: Contribution to journal › Article (Academic Journal) › peer-review

Open Access

File

43 Citations (Scopus)

334 Downloads (Pure)

Professor Christiane H Berger-Schaffitzel

Research output

Search results