Personal profile
Research interests
I am a Postdoctoral Senior Research Associate that has 11 years experience in the field of type 1 diabetes and related autoimmunity. I completed by PhD at the University of Bristol in December 2021 that aimed to understand the natural history of a major humoral response in type 1 diabetes.
My postdoctoral research primarily focuses on utilising islet autoantibodies and other biomarkers to predict, classify, and understand autoimmunity in type 1 diabetes and related autoimmunity. I am enthusiastic and passionate about research focused at improving health and lifestyle outcomes. Improved biomarkers could help to identify individuals for trials aimed at preserving beta-cell function and reducing diabetes complications in the future.
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Collaborations and top research areas from the last five years
Research output
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Improved prediction of symptomatic type 1 diabetes using a luciferase-based assay to measure (pro)insulin autoantibodies
Wyatt, R., Brigatti, C., Grace, S. L., Williams, C. L., Marzinotto, I., Gillard, B. T., Bazzigaluppi, E., Shoemark, D. K., Chandler, M. A., Achenbach, P., Piemonti, L., Gillespie, K. M., Lampasona, V., Williams, A. J. K. & Long, A. E., 22 Jan 2026, (Accepted/In press) In: Diabetic Medicine.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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A novel, high-performance, low-volume, rapid luciferase immunoprecipitation system (LIPS) assay to detect autoantibodies to zinc transporter 8
Williams, C. L., Marzinotto, I., Brigatti, C., Gillespie, K. M., The Box Study, G., Lampasona, V., Williams, A. J. K. & Long, A. E., 1 Mar 2024, In: Clinical and Experimental Immunology. 215, 3, p. 215-224 10 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access11 Citations (Scopus) -
Autoantibodies to truncated GAD(96-585) antigen stratify risk of early insulin requirement in adult-onset diabetes
Grace, S. L., Gillespie, K. M., Williams, C. L., Lampasona, V., Achenbach, P., Pearson, E., Williams, A. J. K., Long, A. E., McDonald, T. & Jones, A., 1 Oct 2024, In: Diabetes. 73, 10, p. 1583-1591 9 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile1 Citation (Scopus)46 Downloads (Pure)
Projects
- 2 Finished
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Examination of pancreatic exocrine function/mass after type 1 diabetes diagnosis
Williams, C. L. (Principal Investigator)
1/06/23 → 31/05/24
Project: Research
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The natural history of the autoimmune response to zinc transporter 8 in type 1 diabetes (PhD; Diabetes UK funded)
Williams, C. L. (Principal Investigator)
2/10/17 → 10/10/21
Project: Research
Prizes
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Best Abstract Award & Travel Grant - 1st EASD Early Career Academy Meeting - Spotlight on Top Research Session.
Williams, C. L. (Recipient), 28 Apr 2025
Prize: Prizes, Medals, Awards and Grants
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British Society for Immunology (BSI) Conference Travel Grant
Williams, C. L. (Recipient), 19 May 2023
Prize: Prizes, Medals, Awards and Grants
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Diabetes UK Basic Science Digital Poster Award 2021
Williams, C. L. (Recipient), 30 Apr 2021
Prize: Prizes, Medals, Awards and Grants
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Diabetes UK Professional Conference 2024
Williams, C. L. (Participant)
17 Apr 2024 → 19 Apr 2024Activity: Participating in or organising an event types › Participation in conference
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The immunology of long-haul disease organised by the British Society for Immunology Bristol Immunology Group
Williams, C. L. (Participant)
19 Jun 2023Activity: Participating in or organising an event types › Participation in conference
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The Immunology of Diabetes Society (IDS) Congress 2023, Paris, France.
Williams, C. L. (Participant)
23 May 2023 → 27 May 2023Activity: Participating in or organising an event types › Participation in conference
Thesis
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The natural history of the autoimmune response to zinc transporter 8 (ZnT8) in type 1 diabetes
Williams, C. L. (Author), Long, A. E. (Supervisor), Williams, A. J. K. (Supervisor) & Gillespie, K. M. (Supervisor), 25 Jan 2022Student thesis: Doctoral Thesis › Doctor of Philosophy (PhD)
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