Research output per year
Research output per year
Personal profile
Research interests
Claire Perks completed her PhD from the University of Bristol in 1995, in which she studied ‘The Role of the IGF axis in the Ovary’ in relation to fertility. She then continued these studies as a Postdoctoral Research Scientist at The Royal Veterinary College, University of London before joining The University of Bristol (UoB) as a Research Associate iin the Department of Surgery. Claire is currently an Associate Professor in Tumour Cell Biology and leads the IGF & Metabolic Endocrinology group in the Bristol Medical School based at Southmead Hospital. Claire's primary interests are in the role of the IGF axis in relation to chronic diseases, particularly cancer. The IGF axis has been conserved throughout evolution to mediate the effects of nutrition on growth and has been implicated in the epithelial cancers associated with a Western diet. Claire is particularly interested in studying the impact of disturbed metabolism on the IGF axis and how this may influence risk and progression of cancer.
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Research output
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Alteration of Metabolic Conditions Impacts the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer
Kingshott, G. G., Biernacka, K. M., Sewell, A. W., Barker, R. M., Zielinska, H. A., Mccarthy, K., Martin, R. M., Lane, J. A., Rowe, E., Oxley, J., Holly, J. M. P. & Perks, C. M., 16 Feb 2021, In: Cancers. 13, 4, p. 1-18 18 p., 825.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile -
A single arm phase II trial of neoadjuvant cabazitaxel and cisplatin chemotherapy for muscle invasive transitional cell carcinoma of the urinary bladder
Challapalli, A., Masson, S., White, P., Dailami, N., Pearson, S., Rowe, E., Koupparis, A., Oxley, J., Abdelaziz, A., Ash-Miles, J., Bravo, A., Foulstone, E., Perks, C., Holly, J., Persad, R. & Bahl, A., 18 Feb 2021, (E-pub ahead of print) In: Clinical Genitourinary Cancer.Research output: Contribution to journal › Article (Academic Journal) › peer-review
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CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer
Uzor, S., Porazinski, S., Li, L., Clark, B., Ajiro, M., lida, K., Hagiwara, M., Alqasem, A. I. M., Perks, C. M., Wilson, I., Oltean, S. & Ladomery, M. R., 12 Apr 2021, In: Scientific Reports. 11, 1, 12 p., 7963 (2021).Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile