If you made any changes in Pure these will be visible here soon.

Personal profile

Research interests

Claire Perks completed her PhD from the University of Bristol in 1995, in which she studied ‘The Role of the IGF axis in the Ovary’ in relation to fertility. She then continued these studies as a Postdoctoral Research Scientist at The Royal Veterinary College, University of London before joining Professor Jeff Holly’s team as a Research Associate in the University of Bristol, Department of Surgery. Claire is currently a Reader in Tumour Cell Biology in the University of Bristol IGF & Metabolic Endocrinology group based at Southmead Hospital. Claire's primary interests are in the role of the IGF axis in relation to breast and prostate cancer. The IGF axis has been conserved throughout evolution to mediate the effects of nutrition on growth and has been implicated in the epithelial cancers associated with a Western diet. Claire is particularly interested in studying the interactions of key dietary factors with the IGF axis and how this may influence breast and prostate cancer progression.

Fingerprint Dive into the research topics where Claire M Perks is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output

  • 68 Article (Academic Journal)
  • 1 Chapter in a book
  • 1 Review article (Academic Journal)

BCATC modulates crosstalk between the PIK/AKT and the RAS/ERK pathway regulating proliferation in triple negative breast cancer

Shafei, M., Forshaw, T., Davis, J., Flemban, A., Qualtrough, J. D., Dean, S., Perks, C. M., Dong, M., Newman, R. & Conway, M., 14 Apr 2020, (Accepted/In press) In : Oncotarget.

Research output: Contribution to journalArticle (Academic Journal)

  • IGF-1 and Hyperglycaemia-induced FOXA1 and IGFBP-2 affect epithelial to mesenchymal transition in prostate epithelial cells

    Mansor, R., Holly, J. M. P., Barker, R. M., Biernacka, K. M., Zielinska, H. A., Koupparis, A. J., Rowe, E., Oxley, J., Sewell, A., Martin, R. M., Lane, J. A., Hackshaw-McGeagh, L. & Perks, C. M., 30 May 2020, (Accepted/In press) In : Oncotarget.

    Research output: Contribution to journalArticle (Academic Journal)

  • Open Access
    File
  • 9 Downloads (Pure)

    Supervised Work

    Does the IGF axis influence EMT to play a role in bladder cancer progression?

    Author: Tang, S., 23 Jan 2019

    Supervisor: Perks, C. (Supervisor) & Holly, J. M. P. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File

    Examining the Role of Placental-derived MicroRNA Secretions in Response to Gestational Hypoxia on Foetal Neurodevelopment

    Author: Bignell, A. L., 23 Jan 2020

    Supervisor: Case, C. P. (Supervisor), Perks, C. M. (Supervisor), Uney, J. B. (Supervisor) & Fulga, T. A. (External person) (Supervisor)

    Student thesis: Master's ThesisMaster of Science (MSc)

    File

    Repositioning aspirin and metformin to improve prostate cancer treatment and outcome

    Author: Carr, H., 19 Mar 2019

    Supervisor: Perks, C. (Supervisor), Williams, A. (Supervisor), Holly, J. M. P. (Supervisor) & Martin, R. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

    File