Projects per year
Personal profile
Research interests
My research interests are the neural and cellular substrates of learning and memory processes in animals. I am specifically interested in the distinct contributions the perirhinal and prefrontal cortices and the hippocampal formation make to recognition memory processing.
The work conducted by my research group has involved the use of a number of complementary behavioural, pharmacological and molecular techniques to examine the neural basis of recognition memory. In earlier experiments we revealed the differential roles played by the perirhinal cortex, hippocampus and prefrontal cortex in specific components of recognition memory, namely familiairity discrimination (our ability to tell if a stimulus such as an object, is familiar or novel); object-in-place associaitive recognition memory (our ability to tell if an object has changed its location); recency recognition memory (our ability to judge how recently an object has been encountered) .
The research uses a multidisciplinary approach incorporating molecular and cellular techniques with behavioural analysis of recognition memory. Most recently my lab have used pharmacogenetics and optogenetics to manipulate specific neural pathways between defined brain regions during specific phases of memory to uncover the nature of information processing across brain wide memory circuits.
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Collaborations and top research areas from the last five years
Projects
- 5 Finished
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Establishing circuit, neuronal and synaptic mechanisms of associative recognition memory
1/09/17 → 31/08/22
Project: Research
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Research output
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A critical role for long-term potentiation mechanisms in the maintenance of object recognition memory in perirhinal cortex revealed by the infusion of zeta inhibitory pseudosubstrate
Outram, A. R., Brown, M. W., Warburton, C. & Barker, G. R. I., 3 Oct 2022, In: Frontiers in Behavioral Neuroscience. 16, 11 p., 970291.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)16 Downloads (Pure) -
Plasticity in Prefrontal Cortex Induced by Coordinated Synaptic Transmission Arising from Reuniens/Rhomboid Nuclei and Hippocampus
Banks, P. J., Warburton, C. & Bashir, Z. I., 14 Apr 2021, In: Cerebral cortex communications. 2, 2, p. 1-16 16 p., tgab029.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile34 Downloads (Pure) -
Why do hippocampal mossy cells matter? It depends on the frequency and context
Kolaric, K., Strauch, C., Li, Y., Woods, S. M., Lopes, M. A., Sivarajah, N., Teixeira, C. M., Lerch, J., Frankland, P. W., Henkelman, M., Bortolotto, Z. A., Warburton, C., Bashir, Z. I., Vaughan, D. M. & Atan, D., 6 Dec 2021, (Submitted).Research output: Working paper › Preprint