Research output per year
Research output per year
Personal profile
Research interests
I have several academic/research interests arising from my background in industry R&D and academic research. I'm interested in polymicrobial biofilms and inter-kingdom interactions between oral bacteria and the fungus Candida albicans, and how virulence and pathogenicity can be modulated by oral bacteria. I'm also interested in modelling infections through use of 3D tissue models (developed and cultured in vitro) and host responses to the biofilm infections, and using probitoics to selectively modulate virulence in vitro and in vivo.
My more recent research involved characterising genes involved in Streptococcus pneumoniae virulence and pathgenicity through molecular biology techniques such as cloning, gene knockout and gene expression analyses including RNAseq, qPCR.
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Collaborations and top research areas from the last five years
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Targeted control of pneumolysin production by a mobile genetic element in Streptococcus pneumoniae
Stevens, E. J., Morse, D. J., Bonini, D., Duggan, S., Brignoli, T., Recker, M., Lees, J. A., Croucher, N. J., Bentley, S., Wilson, D. J., Earle, S. G., Dixon, R., Nobbs, A., Jenkinson, H., van Opijnen, T., Thibault, D., Wilkinson, O. J., Dillingham, M. S., Carlile, S., McLoughlin, R. M., & 1 others, 13 Apr 2022, In: Microbial Genomics. 8, 4, 14 p., 000784.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile3 Citations (Scopus)38 Downloads (Pure) -
Post-acute COVID-19 associated with evidence of bystander T-cell activation and a recurring AMR bacterial pneumonia
Gregorova, M., Morse, D., Brignoli, T., Steventon, J., Hamilton, F., Albur, M., Arnold, D., Thomas, M., Halliday, A., Baum, H., Rice, C., Avison, M. B., Davidson, A. D., Santopaolo, M., Oliver, E., Goenka, A., Finn, A., Wooldridge, L., Amulic, B., Boyton, R. J., & 10 others, 17 Dec 2020, (E-pub ahead of print) In: eLife. 9, 13 p., e63430.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open AccessFile16 Citations (Scopus)61 Downloads (Pure) -
Post-acute COVID-19 associated with evidence of bystander T-cell activation and a recurring antibiotic-resistant bacterial pneumonia.
Gregorova, M., Morse, D., Brignoli, T., Steventon, J., Hamilton, F. W., Rivino, L. & Massey, R. C., 2020, (Submitted).Research output: Working paper