20162020

Research output per year

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Personal profile

Research interests

The lab uses the technique of Cryo-Electron Microscopy to understand the molecular basis of heart disease.   We are developing image processing tools that use Machine Learning and AI to identify the regions of interest in proteins critical to the function of cardiac muscle. 

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Research Output

  • 4 Article (Academic Journal)

In situ cryo-electron tomography reveals filamentous actin within the microtubule lumen

Paul, D. M., Mantell, J. M., Borucu, U., Coombs, J., Surridge, K. J., Squire, J. M., Verkade, P. & Dodding, M. P., 1 Jun 2020, In : Journal of Cell Biology. 219, 9, 14 p., e201911154.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
  • 18 Downloads (Pure)

    After the revolution: how is Cryo-EM contributing to muscle research?

    Bradshaw, M. & Paul, D. M., 13 Jul 2019, In : Journal of Muscle Research and Cell Motility. 40, 2, p. 93-98 6 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 1 Citation (Scopus)
    106 Downloads (Pure)

    Relaxed and active thin filament structures; a new structural basis for the regulatory mechanism

    Paul, D., Squire, J. & Morris, E., Mar 2017, In : Journal of Structural Biology. 197, 3, p. 365-371 7 p.

    Research output: Contribution to journalArticle (Academic Journal)

    Open Access
    File
  • 14 Citations (Scopus)
    246 Downloads (Pure)

    Supervised Work

    Structural characterisation of large macromolecular complexes using cryo-TEM

    Author: Coombs, J., 23 Jan 2020

    Supervisor: Verkade, P. (Supervisor) & Paul, D. M. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy (PhD)

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