Dr Darryl J Hill

B.Sc., Ph.D.(Wales)

  • BS8 1TD

20002020

Research output per year

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Research Output

  • 21 Article (Academic Journal)
  • 3 Chapter in a book
2020
Open Access
File
21 Downloads (Pure)
2019

Agent-based modelling study of antimicrobial resistant Neisseria gonorrhoeae transmission in men who have sex with men: towards individualised diagnosis and treatment

Zienkiewicz, A., Verschueren van Rees, N., Homer, M., Ong, J., Christensen, H., Hill, D., Looker, K., Horner, P. J., Hughes, G. & Turner, K., 3 Sep 2019, In : Sexual Health. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
1 Citation (Scopus)
110 Downloads (Pure)

Fusobacterium spp. target human CEACAM1 via the trimeric autotransporter adhesin CbpF

Brewer, M. L., Dymock, D., Brady, R. L., Singer, B. B., Virji, M. & Hill, D. J., Jan 2019, In : Journal of Oral Microbiology . 11, 1, 16 p., 1565043 .

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
403 Downloads (Pure)
2018

Bioinformatic analysis of meningococcal Msf and Opc to inform vaccine antigen design

Andreae, C., Sessions, R., Virji, M. & Hill, D., 16 Mar 2018, In : PLoS ONE. 13, 3, 21 p., 193940.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
254 Downloads (Pure)
2016

Comparative Genomic Analyses of the Moraxella catarrhalis Serosensitive and Seroresistant Lineages Demonstrate Their Independent Evolution

Earl, J. P., de Vries, S. P. W., Ahmed, A., Powell, E., Schultz, M. P., Hermans, P. W. M., Hill, D. J., Zhou, Z., Constantinidou, C., Hu, F. Z., Bootsma, H. J. & Ehrlich, G. D., 6 Apr 2016, In : Genome Biology and Evolution. 8, 4, p. 955-974 20 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
303 Downloads (Pure)

Helicobacter pylori adhesin HopQ engages in a virulence-enhancing interaction with human CEACAMs

Javaheri, A., Kruse, T., Moones, K., Mejías-Luque, R., Debraekeleer, A., Asche, I., Tegtmeyer, N., Kalali, B., Bach, N., Sieber, S. A., Hill, D., Königer, V., Hauck, C. R., Moskalenko, R., Haas, R., Busch, D. H., Klaile, E., Slevogt, H., Schmidt, A., Backert, S. & 3 others, Remaut, H., Singer, B. B. & Gerhard, M., 17 Oct 2016, In : Nature Microbiology. 2, 16189.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
100 Citations (Scopus)
529 Downloads (Pure)
2015

Identification and therapeutic potential of a vitronectin binding region of meningococcal msf

Hill, D. J., Griffiths, N. J., Borodina, E., Andreae, C. A., Sessions, R. B. & Virji, M., 2015, In : PLoS ONE. 10, 3, p. e0124133

Research output: Contribution to journalArticle (Academic Journal)

8 Citations (Scopus)
2014

Moraxella catarrhalis adhesin UspA1-derived recombinant fragment rD-7 induces monocyte differentiation to CD14+CD206+ phenotype

Xie, Q., Brackenbury, L., Hill, D., Williams, N., Qu, X. & Virji, M., 5 Mar 2014, In : PLoS ONE. 9, 3, 12 p., e90999.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
247 Downloads (Pure)
2013

Haemophilus influenzae meningitis

Hill, D. J. & Christodoulides, M., Aug 2013, Meningitis: cellular and molecular basis. CABI Publishing, p. 91-103

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

67 Citations (Scopus)
2012

A Novel Group of Moraxella catarrhalis UspA Proteins Mediates Cellular Adhesion via CEACAMs and Vitronectin

Hill, D. J., Whittles, C. & Virji, M., 25 Sep 2012, In : PLoS ONE. 7, 9, 15 p., e45452.

Research output: Contribution to journalArticle (Academic Journal)

17 Citations (Scopus)

Meningococcal ligands and molecular targets of the host

Hill, DJ. & Virji, M., 2012, Neisseria meningitidis: Advanced Methods and Protocols. Christodoulides, M. (ed.). Humana Press, p. 143 - 152 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

10 Citations (Scopus)
2011

Meningococcal surface fibril (Msf) binds to activated vitronectin and inhibits the terminal complement pathway to increase serum resistance

Griffiths, NJE., Hill, DJ., Borodina, E., Sessions, RB., Devos, IE., Feron, CM., Poolman, JT. & Virji, M., Dec 2011, In : Molecular Microbiology. 82, 5, p. 1129 - 1149 21 p.

Research output: Contribution to journalArticle (Academic Journal)

41 Citations (Scopus)
2010

Cellular and molecular biology of Neisseria meningitidis colonization and invasive disease

Hill, DJ., Griffiths, NJE., Borodina, E. & Virji, M., May 2010, In : Clinical Science. 118, p. 547 - 564 18 p.

Research output: Contribution to journalArticle (Academic Journal)

111 Citations (Scopus)
2009

Dymanics of Neisseria meningitidis interactions with human cellular barriers and immune effectors

Griffiths, NJE., Sa E Cunha, C., Murillo, I., Youssef, A-R., Borodina, E., Hill, DJ. & Virji, M., May 2009, In : Vaccimonitor. 18, p. 88 - 90 3 p.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)

Meningococcal interactions with the host

Carbonnelle, E., Hill, D. J., Morand, P., Griffiths, N. J., Bourdoulous, S., Murillo Cabeza, I., Nassif, X. & Virji, M., 24 Jun 2009, In : Vaccine. 27, 2, p. B78-B89 12 p.

Research output: Contribution to journalArticle (Academic Journal)

68 Citations (Scopus)
2008

The Moraxella adhesin UspA1 binds to its human CEACAM1 receptor by a deformable trimeric coiled-coil

Conners, R., Hill, D. J., Borodina, E., Agnew, C., Daniell, S. J., Burton, N. M., Sessions, R. B., Clarke, A. R., Catto, L. E., Lammie, D., Wess, T., Brady, R. L. & Virji, M., 18 Jun 2008, In : EMBO Journal. 27, 12, p. 1779-1789 11 p.

Research output: Contribution to journalArticle (Academic Journal)

53 Citations (Scopus)
2007

Co-ordinate action of bacterial adhesins and human carcinoembryonic antigen receptors in enhanced cellular invasion by capsulate serum resistant Neisseria meningitidis

Rowe, HA., Griffiths, NJE., Hill, DJ. & Virji, M., Jan 2007, In : Cellular Microbiology. 9 (1), p. 154 - 168 15 p.

Research output: Contribution to journalArticle (Academic Journal)

23 Citations (Scopus)

Mutational analysis of human CEACAM1: the potential of receptor polymorphism in increasing host susceptibility to bacterial infection

Villullas Rincon, S., Hill, DJ., Sessions, R., Rea, JR. & Virji, M., Feb 2007, In : Cellular Microbiology. 9 (2), p. 329 - 346 18 p.

Research output: Contribution to journalArticle (Academic Journal)

18 Citations (Scopus)
2005

Carcinoembryonic antigen-related cell adhesion molecule (CEACAM)-binding recombinant polypeptide confers protection against infection by respiratory and urogenital pathogens

Hill, DJ., Edwards, AM., Rowe, HA. & Virji, M., Mar 2005, In : Molecular Microbiology. 55 (5), p. 1515 - 1527 13 p.

Research output: Contribution to journalArticle (Academic Journal)

45 Citations (Scopus)

Evidence that the purinergic receptor P2Y12 potentiates platelet shape change by a Rho kinase-dependent mechanism

Hardy, AR., Hill, DJ. & Poole, AW., Nov 2005, In : Platelets. 16(7), p. 415 - 429 15 p.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)
2003
113 Citations (Scopus)
2002

In vitro models of infection II--human umbilical vein endothelial cells (HUVECs) system

Virji, M. & Hill, DJ., 2002, Hemophilus influenzae Protocols (Methods in Molecular Medicine series). Herbert, M., Hood, D. W. & Moxon, E. R. (eds.). Humana Press, Vol. 71. p. 297 - 314 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

2001

The variable P5 proteins of typeable and non-typeable Haemophilus influenzae target human CEACAM1

Hill, DJ., Toleman, MA., Evans, DJ., Villullas Rincon, S., Van Alphen, L. & Virji, M., Feb 2001, In : Molecular Microbiology. 39 (4), p. 850 - 862 13 p.

Research output: Contribution to journalArticle (Academic Journal)

93 Citations (Scopus)
2000

Carcinoembryonic antigens are targeted by diverse strains of typable and non-typable Haemophilus influenzae

Virji, M., Evans, DJ., Griffith, JE., Hill, DJ., Serino, L., Hadfield, AT. & Watt, SM., May 2000, In : Molecular Microbiology. 36, p. 784 - 795 12 p.

Research output: Contribution to journalArticle (Academic Journal)

93 Citations (Scopus)