Research output per year
Research output per year
Personal profile
Research interests
- Mechanisms of innate immune cell activation and tissue damage in ocular inflammatory and neovascular conditions.
- Control of immune responses to promote/restore tissue homeostasis and function in the eye.
- In vivo ocular imaging, using Topical Endoscopic Fundal Imaging (TEFI), Fundal Fluorescein Angiography (FA) and Optical Coherence Tomography (OCT) platforms.
- Preclinical testing of novel therapeutic approaches using ocular disease models.
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Dive into the research topics where David A Copland is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Research output
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A pathogenic CD4 T cell phenotype in experimental uveitis shares common features with other immune mediated inflammatory diseases
Ward, A., Bell, O. H., Martinez-Robles, L., Lait, P. J. P., Chu, C. J., Copland, D. A., Dick, A. D. & Nicholson, L. B., 19 Jun 2025, bioRxiv.org, 22 p.Research output: Working paper › Preprint
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Characterization of the ocular inflammatory response to AAV reveals divergence by sex and age
Clare, A. J., Langer, P. M., Ward, A., Chan, Y. K., Dick, A. D. & Copland, D. A., 17 Jan 2025, (E-pub ahead of print) In: Molecular Therapy. 33, 3, p. 1246-1263 18 p.Research output: Contribution to journal › Article (Academic Journal) › peer-review
Open Access4 Citations (Scopus) -
Gene Therapy-Associated Uveitis (GTAU): Understanding and mitigating the adverse immune response in retinal gene therapy
Purdy, R., John, M., Bray, A., Clare, A. J., Copland, D. A., Chan, Y. K., Henderson, R. H., Nerinckx, F., Leroy, B. P., Yang, P., Pennesi, M. E., MacLaren, R. E., Fischer, M. D., Dick, A. D. & Xue, K., 26 Mar 2025, In: Progress in Retinal and Eye Research. 106, 26 p., 101354.Research output: Contribution to journal › Review article (Academic Journal) › peer-review
Open Access2 Citations (Scopus)
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A novel dual-target gene therapy for safe and efficacious treatment of chronic non-infectious uveitis
Copland, D. A. (Principal Investigator)
1/06/24 → 31/05/26
Project: Research
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Preventing AAV gene therapy associated inflammation with immunomodulatory drugs
Clare, A. J. (Principal Investigator), Copland, D. A. (Co-Investigator), Dick, A. D. (Co-Investigator) & Langer, P. (Student)
31/01/24 → 30/01/25
Project: Research
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8066 NERC: Overcoming immune resPonses to retinal gene theropy
Copland, D. A. (Principal Investigator)
1/09/21 → 31/08/24
Project: Research