19962020

Research output per year

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Research Output

2020

Cytoplasmic dynein-2 at a glance

Vuolo, L., Stevenson, N. L., Mukhopadhyay, A. G., Roberts, A. J. & Stephens, D., 30 Mar 2020, In : Journal of Cell Science.

Research output: Contribution to journalArticle (Academic Journal)

2019

Developing pathways to clarify pathogenicity of unclassified variants in Osteogenesis Imperfecta genetic analysis

Balasubramanian, M., Hobson, E., Skae, M., McCaughey, J. & Stephens, D., 8 Dec 2019, In : Molecular genetics & genomic medicine. 7, 12, 10 p., e912.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
89 Downloads (Pure)

ER-to-Golgi trafficking of procollagen in the absence of large carriers

McCaughey, J., Stevenson, N. L., Cross, S. & Stephens, D. J., 4 Mar 2019, In : Journal of Cell Biology. 218, 3, p. 929-948 20 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
258 Downloads (Pure)

ER-to-Golgi Transport: A Sizeable Problem

McCaughey, J. & Stephens, D. J., 1 Dec 2019, In : Trends in Cell Biology. 29, 12, p. 940-953 14 p.

Research output: Contribution to journalReview article (Academic Journal)

4 Citations (Scopus)

Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex

Gerondopoulos, A., Strutt, H., Stevenson, N. L., Sobajima, T., Levine, T. P., Stephens, D. J., Strutt, D. & Barr, F. A., 7 Oct 2019, In : Current Biology. 29, 19, p. 3323 - 3330.e8 17 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
3 Citations (Scopus)
100 Downloads (Pure)
2018

COPII-dependent ER export in animal cells: adaptation and control for diverse cargo

McCaughey, J. & Stephens, D. J., 18 Jun 2018, In : Histochemistry and Cell Biology. 13 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
15 Citations (Scopus)
257 Downloads (Pure)

Dynein-2 intermediate chains play crucial but distinct roles 2 in primary cilia formation and function

Vuolo, L., Stevenson, N., Heesom, K. & Stephens, D., 16 Oct 2018, In : eLife. 7, 29 p., e39655.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
7 Citations (Scopus)
213 Downloads (Pure)

Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control

Stevenson, N. L., Bergen, D. J. M., Xu, A., Wyatt, E., Henry, F., McCaughey, J., Vuolo, L., Hammond, C. L. & Stephens, D. J., 1 May 2018, In : Journal of Cell Science. 131, 9, 8 p., jcs212258.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
4 Citations (Scopus)
169 Downloads (Pure)
2017

Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity

Evans, A. J., Gurung, S., Wilkinson, K. A., Stephens, D. J. & Henley, J. M., 20 Jun 2017, In : Cell Reports. 19, 12, p. 2613-2626 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
16 Citations (Scopus)
284 Downloads (Pure)

Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression

Stevenson, N. L., Bergen, D. J. M., Skinner, R. E. H., Kague, E., Martin-Silverstone, E., Robson Brown, K. A., Hammond, C. L. & Stephens, D. J., 1 Dec 2017, In : Journal of Cell Science. 130, 24, p. 4132-4143 12 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
14 Citations (Scopus)
246 Downloads (Pure)

P4HB recurrent missense mutation causing Cole-Carpenter syndrome

Balasubramanian, M., Padidela, R., Pollitt, R. C., Bishop, N. J., Mughal, M. Z., Offiah, A. C., Wagner, B. E., McCaughey, J. & Stephens, D. J., 19 Dec 2017, In : Journal of Medical Genetics. 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
10 Citations (Scopus)
184 Downloads (Pure)

The Golgi matrix protein giantin is required for normal cilia function in zebrafish

Bergen, D., Stephens, D., Stevenson, N. & Hammond, C. L., 15 Aug 2017, In : Biology Open. 6, 8, p. 1180-1189 10 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
9 Citations (Scopus)
250 Downloads (Pure)
2016

Insulin promotes Rip11 accumulation at the plasma membrane by inhibiting a dynamin- and PI3-kinase-dependent, but Akt-independent, internalisation event

Boal, F., Hodgson, L. R., Reed, S. E., Yarwood, S. E., Just, V. J., Stephens, D. J., McCaffrey, M. W. & Tavaré, J. M., Jan 2016, In : Cellular Signalling. 28, 1, p. 74-82 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
224 Downloads (Pure)

TFG Promotes Organization of Transitional ER and Efficient Collagen Secretion

McCaughey, J., Miller, V. J., Stevenson, N., Brown, A., Budnik, A., Heesom, K., Alibhai, D. R. & Stephens, D., 24 May 2016, In : Cell Reports. 15, 8, p. 1648-59 12 p., 15.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
28 Citations (Scopus)
370 Downloads (Pure)
2014

Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation

Bonavita, R., Walas, D., Townley, A. K., Luini, A., Stephens, D. J. & Colanzi, A., 27 May 2014, In : Biology of the Cell.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)

Opposing microtubule motors control motility, morphology and cargo segregation during ER-to-Golgi transport

Brown, A. K., Hunt, S. D. & Stephens, D. J., 4 Apr 2014, In : Biology Open.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

Subunit composition of the human cytoplasmic dynein-2 complex

Asante, D., Stevenson, N. L. & Stephens, D. J., 31 Oct 2014, In : Journal of Cell Science. 127, 21, p. 4774-4787 14 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
40 Citations (Scopus)
417 Downloads (Pure)
2013

A role for endoplasmic reticulum exit sites (ERES) in foot-and-mouth disease virus infection

Midgley, R., Moffat, K., Berryman, S., Hawes, P., Simpson, J., Fullen, D., Stephens, D. J., Burman, A. & Jackson, T., 20 Aug 2013, In : Journal of General Virology.

Research output: Contribution to journalArticle (Academic Journal)

13 Citations (Scopus)

A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2

Asante, D., MacCarthy-Morrogh, L. J., Townley, A. K., Weiss, M., Katayama, K., Palmer, K. J., Suzuki, H., Westlake, C. & Stephens, D., 15 Nov 2013, In : Journal of Cell Science. 126, p. 5189-5197

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
25 Citations (Scopus)
452 Downloads (Pure)

Characteristic phenotypes associated with Congenital Dyserythropoietic Anemia (Type II) manifest at different stages of erythropoiesis

Satchwell, T. J., Pellegrin, S., Bianchi, P., Hawley, B. R., Gampel, A., Mordue, K. E., Budnik, A., Fermo, E., Barcellini, W., Stephens, D. J., Van den Akker, E. & Toye, A. M., 9 Aug 2013, In : Haematologica.

Research output: Contribution to journalArticle (Academic Journal)

22 Citations (Scopus)

Early stages of retinal development depend on Sec13 function

Schmidt, K., Cavodeassi, F., Feng, Y. & Stephens, D. J., 15 Mar 2013, In : Biology Open. 2, 3, p. 256-266 11 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
11 Citations (Scopus)
397 Downloads (Pure)

Membrane contact sites - an interesting species, an interesting mix

Miller, V. J. & Stephens, D. J., 5 Apr 2013, In : EMBO Reports. 14, 5, p. 396-397 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
447 Downloads (Pure)

Microtubule motors mediate endosomal sorting by maintaining functional domain organization

Hunt, S. D., Townley, A. K., Danson, C. M., Cullen, P. J. & Stephens, D. J., 2 Apr 2013, In : Journal of Cell Science. 126, 11, p. 2493-2501 9 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
32 Citations (Scopus)
484 Downloads (Pure)

Preface (Methods in Cell Biology)

Stephens, D. & Perez, F., 2013, In : Methods in Cell Biology. 118, p. xix-xx

Research output: Contribution to journalArticle (Academic Journal)

RNA interference approaches to examine Golgi function in animal cell culture

Miller, V. J., McKinnon, C. M., Mellor, H. & Stephens, D. J., 2013, In : Methods in Cell Biology. 118, p. 15-34 20 p.

Research output: Contribution to journalArticle (Academic Journal)

3 Citations (Scopus)

The Endoplasmic Reticulum COPII-Vesicle Transport Machinery Coordinates Cellular Lipid Secretion and Cholesterol Biosynthesis

Fryer, L. G. D., Jones, B., Duncan, E. J., Hutchison, C. E., Ozkan, T., Williams, P. A., Alder, O., Nieuwdorp, M., Townley, A. K., Mensenkamp, A. R., Stephens, D. J., Dallinga-Thie, G. M. & Shoulders, C. C., 13 Dec 2013, In : Journal of Biological Chemistry.

Research output: Contribution to journalArticle (Academic Journal)

19 Citations (Scopus)
2012

Cell biology: Collagen secretion explained

Stephens, D. J., 23 Feb 2012, In : Nature. 482, 7386, p. 474-475 2 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
21 Citations (Scopus)
492 Downloads (Pure)

Epithelial organization and cyst lumen expansion require efficient Sec13-Sec31-driven secretion

Townley, A. K., Schmidt, K., Hodgson, L. & Stephens, D. J., 2012, In : Journal of Cell Science. 125, 3, p. 673-84 12 p.

Research output: Contribution to journalArticle (Academic Journal)

File
14 Citations (Scopus)
476 Downloads (Pure)

Functional coupling of microtubules to membranes - implications for membrane structure and dynamics

Stephens, D. J., 2012, In : Journal of Cell Science. 125, 12, p. 2795-2804 10 p.

Research output: Contribution to journalArticle (Academic Journal)

File
18 Citations (Scopus)
381 Downloads (Pure)
2011

A role for Tctex-1 (DYNLT1) in controlling primary cilium length

Palmer, KJ., MacCarthy-Morrogh, LJ., Miss Nicola, S. & Stephens, DJ., 2011, In : European Journal of Cell Biology. 90, 10, p. 865 - 871 7 p.

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
27 Citations (Scopus)
462 Downloads (Pure)

Characterization of human Sec16B: indications of specialized, non-redundant functions

Budnik, A., Heesom, K. & Stephens, DJ., 2011, In : Scientific Reports. 1, 25 p., 77.

Research output: Contribution to journalArticle (Academic Journal)

File
10 Citations (Scopus)
478 Downloads (Pure)

Communication as information use: Insights from statistical decision theory

Kight, C. R., McNamara, J. M., Stephens, D. W. & Dall, S. R. X., 1 Jan 2011, Animal Communication Theory: Information and Influence. Cambridge University Press, p. 89-112 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter in a book

1 Citation (Scopus)

The role of motor proteins in endosomal sorting

Hunt, S. & Stephens, DJ., Oct 2011, In : Biochemical Society Transactions. 39, 5, p. 1179 - 1184

Research output: Contribution to journalArticle (Academic Journal)

Open Access
File
33 Citations (Scopus)
463 Downloads (Pure)
2010

Cargo loading at the ER

Schmidt, K. & Stephens, DJ., Nov 2010, In : Molecular Membrane Biology. 27 (8), p. 398 - 411 14 p.

Research output: Contribution to journalArticle (Academic Journal)

7 Citations (Scopus)

Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells

Guetzoyan, LJ., Spooner, RA., Boal, F., Stephens, DJ., Lord, JM., Roberts, LM. & Clarkson, GJ., Oct 2010, In : Molecular bioSystems. 6 (10), p. 2030 - 2038 9 p.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)

LG186: An inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells

Boal, F., Guetzoyan, L., Sessions, RB., Zeghouf, M., Spooner, RA., Lord, JM., Cherfils, J., Clarkson, GJ., Roberts, LM. & Stephens, DJ., Dec 2010, In : Traffic. 11 (12), p. 1537 - 1551 15 p.

Research output: Contribution to journalArticle (Academic Journal)

28 Citations (Scopus)

Sec16A defines the site for vesicle budding from the endoplasmic reticulum on exit from mitosis

Hughes, H. & Stephens, DJ., Dec 2010, In : Journal of Cell Science. 123 (23), p. 4032 - 4038 7 p.

Research output: Contribution to journalArticle (Academic Journal)

14 Citations (Scopus)

Specific functions of BIG1 and BIG2 in endomembrane organisation

Boal, F. & Stephens, DJ., Mar 2010, In : PLoS ONE. 5 (3), p. e9898 - e9898

Research output: Contribution to journalArticle (Academic Journal)

26 Citations (Scopus)
2009

ER exit sites – Localization and control of COPII vesicle formation

Budnik, A. & Stephens, DJ., Dec 2009, In : FEBS Letters. 583 (23), p. 3796 - 3803 8 p.

Research output: Contribution to journalArticle (Academic Journal)

96 Citations (Scopus)

Imaging in cell and developmental biology

Stephens, D., Oct 2009, In : Seminars in Cell and Developmental Biology. 20 (8), p. 885 - 885 1 p.

Research output: Contribution to journalArticle (Academic Journal)

Organisation of human ER-exit sites: requirements for the localisation of Sec16 to transitional ER

Hughes, H., Budnik, A., Schmidt, K., Palmer, K. J., Mantell, J., Noakes, C., Johnson, A., Carter, D. A., Verkade, P., Watson, P. & Stephens, D. J., Aug 2009, In : Journal of Cell Science. 122 , 16, p. 2924 - 2934 11 p.

Research output: Contribution to journalArticle (Academic Journal)

97 Citations (Scopus)

Specificity of cytoplasmic dynein subunits in discrete membrane-trafficking steps

Palmer, K. J., Hughes, H. & Stephens, D. J., Jun 2009, In : Molecular Biology of the Cell. 20 , 12, p. 2885 - 2899 15 p.

Research output: Contribution to journalArticle (Academic Journal)

83 Citations (Scopus)

The retomer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network

Wassmer, T., Attar, N., Harterink, M., van Weering, J. R. T., Traer, C. J., Oakley, J., Gould, B., Stephens, D. J., Verkade, P., Korswagen, H. C. & Cullen, P. J., Jul 2009, In : Developmental Cell. 17 (1), 1, p. 110 - 122 13 p.

Research output: Contribution to journalArticle (Academic Journal)

189 Citations (Scopus)

Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers

Townley, AK. & Stephens, DJ., Aug 2009, In : F1000 Reports: Biology. 1 (65)

Research output: Contribution to journalArticle (Academic Journal)

2008

Assembly, organization, and function of COPII coat

Hughes, H. & Stephens, DJ., Feb 2008, In : Histochemistry and Cell Biology. 129 (2), p. 129 - 151 23 p.

Research output: Contribution to journalArticle (Academic Journal)

88 Citations (Scopus)

Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated degradation

Wakana, Y., Takai, S., Nakajima, K., Tani, K., Yamamoto, A., Watson, P., Stephens, DJ., Hauri, H-P. & Tagaya, M., May 2008, In : Molecular Biology of the Cell. 19 (5), p. 1825 - 1836 12 p.

Research output: Contribution to journalArticle (Academic Journal)

68 Citations (Scopus)

Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development

Townley, A. K., Feng, Y., Schmidt, K., Carter, D. A., Porter, R., Verkade, P. & Stephens, D. J., Sep 2008, In : Journal of Cell Science. 121 , 18, p. 3025 - 3034 10 p.

Research output: Contribution to journalArticle (Academic Journal)

108 Citations (Scopus)

Kinesin-1 (uKHC/KIF5B) is required for bidirectional motility of ER exit sites and efficient ER-to-Golgi transport

Gupta, V., Palmer, KJ., Spence, P., Hudson, A. & Stephens, DJ., Nov 2008, In : Traffic. 9 (11), p. 1850 - 1866 17 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)

Optimising the precision for localising fluorescent proteins in living cells by 2D Gaussian fitting of digital images: application to COPII-coated endoplasmic reticulum exit sites

Spence, P., Gupta, V., Stephens, DJ. & Hudson, AJ., Oct 2008, In : European Biophysics Journal. 37, 8, p. 1335-1349 15 p.

Research output: Contribution to journalArticle (Academic Journal)

6 Citations (Scopus)

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network

Spooner, RA., Watson, P., Smith, DC., Boal, F., Amessou, M., Johannes, L., Clarkson, GJ., Lord, JM., Stephens, DJ. & Roberts, LM., Sep 2008, In : Biochemical Journal. 414 (3), p. 471 - 484 14 p.

Research output: Contribution to journalArticle (Academic Journal)

33 Citations (Scopus)